Patents Assigned to Acucela Inc.
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Publication number: 20230241410Abstract: A wearer adjustable apparatus is configured for a wearer to view an object and adjust stimuli projected into the eye by adjusting the location of the projection optics, for example with movement of the projection optics relative to one or more components of a support such as an eyeglass frame. In some embodiments, the projection system comprises an adjustable retainer for the wearer to adjust first active projection elements coupled to a first support in front of a first eye in relation to second projection optics coupled to a second support in front of a second eye of the wearer. In some embodiments, the apparatus comprises oculars comprising the projection optics and corrective lenses configured for the wearer to adjust positions of the lenses and projection optics in front of the wearer's eyes in order to project therapeutic spots onto a desired location relative to the wearer's retinas.Type: ApplicationFiled: February 2, 2023Publication date: August 3, 2023Applicant: ACUCELA INC.Inventors: Ryo KUBOTA, Benjamin CROOK, Stefan BAUER, Philip M. BUSCEMI, Amitava GUPTA, Jonas GERMANN
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Publication number: 20230210360Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.Type: ApplicationFiled: March 3, 2023Publication date: July 6, 2023Applicant: ACUCELA INC.Inventors: Lukas SCHEIBLER, Matthias PFISTER, Urban SCHNELL, Stefan TROLLER, Ryo KUBOTA
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Patent number: 11693259Abstract: Systems, devices, apparatuses and methods for an active projection system that may be incorporated into spectacles, contact lenses or provided as an add-on layer to existing spectacles or lenses. The active projection system operates to generate a stimulus or stimuli for viewing by a person's eye. The stimulus or stimuli creates an image that is defocused in front of the person's retina and can assist in slowing or stopping the progression of myopia or other refractive errors in the person.Type: GrantFiled: August 18, 2022Date of Patent: July 4, 2023Assignee: ACUCELA INC.Inventors: Philip M. Buscemi, Ryo Kubota
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Publication number: 20230206440Abstract: A neural network is trained to segment interferogram images. A first plurality of interferograms are obtained, where each interferograms corresponds to data acquired by an OCT system using a first scan pattern, annotating each of the plurality of interferograms to indicate a tissue structure of a retina, training a neural network using the plurality of interferograms and the annotations, inputting a second plurality of interferograms corresponding to data acquired by an OCT system using a second scan pattern and obtaining an output of the trained neural network indicating the tissue structure of the retina that was scanned using the second scan pattern. The system and methods may instead receive a plurality of A-scans and output a segmented image corresponding to a plurality of locations along an OCT scan pattern.Type: ApplicationFiled: March 2, 2023Publication date: June 29, 2023Applicant: ACUCELA INC.Inventors: Stephan WYDER, Matthias PFISTER, Cyril STOLLER, Philip M. BUSCEMI
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Publication number: 20230204980Abstract: An electronic case for electronic spectacles may include a base comprising a cavity formed therein. A first spectacle retention device may be located within the cavity. The first spectacle retention device may be configured to retain spectacles. An electrical control system may be included. An electrical connector may be configured to couple the electrical control system in electronic communication with the spectacles.Type: ApplicationFiled: February 28, 2023Publication date: June 29, 2023Applicant: ACUCELA INC.Inventors: Ryo KUBOTA, Philip M. BUSCEMI, Pascal LOSER, Ben CROOK, Massimo PINAZZA, Jim NIEBANCK, James PHILLIPS, Stefan BAUER
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Patent number: 11684254Abstract: An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. The scan pattern is a continuous pattern that includes a plurality of lobes. The measurement beam may be caused to move on the retina by the motion of a mirror that intercepts and redirects the measurement beam. The mirror position may be altered by the application of a drive signal to one or more actuators that respond to the drive signal by rotating the mirror about an axis or axes.Type: GrantFiled: May 9, 2022Date of Patent: June 27, 2023Assignee: ACUCELA INC.Inventors: Ryo Kubota, Stephan Wyder, Philip M. Buscemi, Matthias Pfister, Alexander Holzer
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Publication number: 20230168521Abstract: A soft contact lens comprises a plurality of light sources coupled to a plurality of optical elements. The plurality of light sources and the plurality of optical elements are embedded in a soft contact lens material. Each of said plurality of optical elements generates an image focused in front of a peripheral retina of a wearer. In some embodiments, each of the images is focused at a distance in front of the peripheral retina at a location, and each of the images comprises a depth of focus and a spatial resolution. The depth of focus can be less than the distance, and the spatial resolution greater than a spatial resolution of the peripheral retina at the location.Type: ApplicationFiled: January 26, 2023Publication date: June 1, 2023Applicant: ACUCELA INC.Inventors: Beat WYSS, Jean-Noel FEHR, Glenn NORONHA, Karim HAROUD, Julien SAUVET, Hans BERNHARD, Christian OGGENFUSS, Amitava GUPTA, Ryo KUBOTA
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Publication number: 20230144121Abstract: A device to stimulate the retina comprises one or more light sources coupled to one or more optical elements. The one or more optical elements is configured to illuminate the retina with one or more images at a location away from a fovea of a wearer. In some embodiments, each of the one or more images comprises a depth of focus and a spatial resolution. The one or more images can be formed at a distance anterior to the retina, at a distance posterior to the retina or on the retina. In some embodiments, the depth of focus is less than the distance, and the spatial resolution greater than a spatial resolution of the retina at the location.Type: ApplicationFiled: January 11, 2023Publication date: May 11, 2023Applicant: ACUCELA INC.Inventors: Ryo KUBOTA, Karim HAROUD, Beat WYSS, Hans BERNHARD, Jean-Noel FEHR, Patrizia WEBER, Moritz HAEBERLI, Amitava GUPTA
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Publication number: 20230118068Abstract: A contact lens configured to decrease dark adaptation comprises one or more LEDs and directs light from the LED away from the fovea and toward the parafovea or perifoveal regions of the retina. In some embodiments, soft contact lens embedded with one or more arrays of microLEDs and electronics operating the LEDs is configured to be worn at night in order to inhibit dark adaptation and reduce oxygen consumption by the rods. The contact lens may be made of a single layer of a contact lens material or multiple layers sandwiching a flexible transparent plastic layer comprising the electronics and the LED arrays. The contact lens may be made of a hydrophilic hydrogel material that is biocompatible to the human cornea, or a silicone hydrogel material. The contact lens may be spherical and may provide refractive correction to the eye of the wearer.Type: ApplicationFiled: December 16, 2022Publication date: April 20, 2023Applicant: ACUCELA INC.Inventors: Amitava GUPTA, Ryo KUBOTA
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Patent number: 11627874Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.Type: GrantFiled: February 10, 2021Date of Patent: April 18, 2023Assignee: ACUCELA INC.Inventors: Lukas Scheibler, Matthias Pfister, Urban Schnell, Stefan Troller, Ryo Kubota
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Patent number: 11630329Abstract: An electronic case for electronic spectacles may include a base comprising a cavity formed therein. A first spectacle retention device may be located within the cavity. The first spectacle retention device may be configured to retain spectacles. An electrical control system may be included. An electrical connector may be configured to couple the electrical control system in electronic communication with the spectacles.Type: GrantFiled: August 17, 2022Date of Patent: April 18, 2023Assignee: ACUCELA INC.Inventors: Ryo Kubota, Philip M. Buscemi, Pascal Loser, Ben Crook, Massimo Pinazza, Jim Niebanck, James Phillips, Stefan Bauer
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Publication number: 20230110912Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.Type: ApplicationFiled: December 12, 2022Publication date: April 13, 2023Applicant: ACUCELA INC.Inventors: Christian OGGENFUSS, Karim HAROUD, Lukas SCHEIBLER, Matthias PFISTER, Urban SCHNELL, Stefan TROLLER, Ryo KUBOTA, Philip BUSCEMI
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Patent number: 11624937Abstract: A contact lens configured to decrease dark adaptation comprises one or more LEDs and directs light from the LED away from the fovea and toward the parafovea or perifoveal regions of the retain. In some embodiments, soft contact lens embedded with one or more arrays of microLEDs and electronics operating the LEDs is configured to be worn at night in order to inhibit dark adaptation and reduce oxygen consumption by the rods. The contact lens may be made of a single layer of a contact lens material or multiple layers sandwiching a flexible transparent plastic layer comprising the electronics and the LED arrays. The contact lens may be made of a hydrophilic hydrogel material that is biocompatible to the human cornea, or a silicone hydrogel material. The contact lens may be spherical and may provide refractive correction to the eye of the wearer.Type: GrantFiled: July 3, 2019Date of Patent: April 11, 2023Assignee: ACUCELA INC.Inventors: Amitava Gupta, Ryo Kubota
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Patent number: 11619831Abstract: A soft contact lens comprises a plurality of light sources coupled to a plurality of optical elements. The plurality of light sources and the plurality of optical elements are embedded in a soft contact lens material. Each of said plurality of optical elements generates an image focused in front of a peripheral retina of a wearer. In some embodiments, each of the images is focused at a distance in front of the peripheral retina at a location, and each of the images comprises a depth of focus and a spatial resolution. The depth of focus can be less than the distance, and the spatial resolution greater than a spatial resolution of the peripheral retina at the location.Type: GrantFiled: June 10, 2022Date of Patent: April 4, 2023Assignee: ACUCELA INC.Inventors: Beat Wyss, Jean-Noël Fehr, Glenn Noronha, Karim Haroud, Julien Sauvet, Hans Bernhard, Christian Oggenfuss, Amitava Gupta, Ryo Kubota
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Patent number: 11620749Abstract: A neural network is trained to segment interferogram images. A first plurality of interferograms are obtained, where each interferograms corresponds to data acquired by an OCT system using a first scan pattern, annotating each of the plurality of interferograms to indicate a tissue structure of a retina, training a neural network using the plurality of interferograms and the annotations, inputting a second plurality of interferograms corresponding to data acquired by an OCT system using a second scan pattern and obtaining an output of the trained neural network indicating the tissue structure of the retina that was scanned using the second scan pattern. The system and methods may instead receive a plurality of A-scans and output a segmented image corresponding to a plurality of locations along an OCT scan pattern.Type: GrantFiled: June 3, 2022Date of Patent: April 4, 2023Assignee: ACUCELA INC.Inventors: Stephan Wyder, Matthias Pfister, Cyril Stoller, Philip M. Buscemi
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Publication number: 20230089006Abstract: A contact lens may include a body of contact lens material extending between a first surface and a second surface. An electromechanical component may be supported in the contact lens material between the first surface and the second surface. A support comprising a plurality of pillars may be formed of the contact lens material and may extend from at least one of the first surface and the second surface to the electromechanical component.Type: ApplicationFiled: November 1, 2022Publication date: March 23, 2023Applicant: ACUCELA INC.Inventors: Ryo KUBOTA, Gordon Frederick MACCABEE, Ferry WIDJAJA, Amitava GUPTA
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Publication number: 20230063265Abstract: A contact lens charging case comprises a container sized and shaped to receive an electronic contact lens (“eCL”) and charging coil to couple to a coil of the eCL. In some embodiments, the charging coil comprises a diameter larger than a diameter of the coil of the eCL, so as to decrease sensitivity of the location and orientation of the eCL in the container and improve coupling between the coils. In some embodiments, the charging coil is dimensioned so as to extend at least partially around the container that receives the eCL.Type: ApplicationFiled: February 19, 2021Publication date: March 2, 2023Applicant: ACUCELA INC.Inventors: Ryo KUBOTA, Patrizia WEBER, Marco BURGENER, Jonas BUTSCHER, Praveenth SANMUGARAJAH, Hans BERNHARD, Amitava GUPTA
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Patent number: 11583696Abstract: A device to stimulate the retina comprises one or more light sources coupled to one or more optical elements. The one or more optical elements is configured to illuminate the retina with one or more images at a location away from a fovea of a wearer. In some embodiments, each of the one or more images comprises a depth of focus and a spatial resolution. The one or more images can be formed at a distance anterior to the retina, at a distance posterior to the retina or on the retina. In some embodiments, the depth of focus is less than the distance, and the spatial resolution greater than a spatial resolution of the retina at the location.Type: GrantFiled: May 5, 2022Date of Patent: February 21, 2023Assignee: ACUCELA INC.Inventors: Ryo Kubota, Karim Haroud, Beat Wyss, Hans Bernhard, Jean-Noël Fehr, Patrizia Weber, Moritz Haeberli, Amitava Gupta
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Patent number: 11576572Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.Type: GrantFiled: May 4, 2022Date of Patent: February 14, 2023Assignee: ACUCELA INC.Inventors: Christian Oggenfuss, Karim Haroud, Lukas Scheibler, Matthias Pfister, Urban Schnell, Stefan Troller, Ryo Kubota, Philip M. Buscemi
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Publication number: 20230026567Abstract: A stimulus is configured to treat astigmatism with changes in retinal thickness, independently of, or in combination with, treatment for myopia. In some embodiments, a stimulus pattern is arranged with respect to an astigmatic axis of the eye to decrease ocular growth in relation to the astigmatic axis. In some embodiments, the apparatus is configured to direct light to regions of retina outside the macula in relation to the astigmatic axis of the eye. In some embodiments, the intensity is modulated to provide the effect. A lens, such as a contact lens or spectacle lens may be configured with a plurality of light sources, such as projection units having a light source and focusing optics that work together to project anteriorly or posteriorly defocused images onto the retina at locations eccentric to the fovea.Type: ApplicationFiled: September 28, 2022Publication date: January 26, 2023Applicant: ACUCELA INC.Inventors: Philip M. BUSCEMI, Ryo KUBOTA