Abstract: A method for treating or preventing a disease, condition or state in a subject in need thereof by administering to the subject an effective amount of the (?)-enantiomer of perhexyline or a pharmaceutically acceptable salt, prodrug or derivative thereof, substantially free of the (+)-enantiomer, or pharmaceutical composition containing same. The disease, condition or state may be associated with altered tissue energetics, impaired tissue energetics, altered cardiac tissue energetics, impaired cardiac tissue energetics, altered hepatic tissue energetics, impaired hepatic tissue energetics, and diabetes.

Abstract: The present invention relates to a method of modulating repair of a wound. The method includes modulating expression and/or activity of Flightless I in cells involved in repair of the wound.

Abstract: A method for estimating the activity topology of a set of sensed data windows is described. Each of the sensed data windows related to a corresponding sensed region. The method includes the steps of determining a subset of sensed data windows that are not connected; and excluding the subset of sensed data windows from the set of sensed data windows. In one embodiment, the sensed data windows corresponding to image windows such as would be provided by a visual surveillance system.

Abstract: The present invention relates to a method of modulating apoptosis of a granulosa cell. The method includes one or more of the following steps: (i) modulating the concentration and/or activity of BMP-15 and/or BMP-6 that the granulosa cell is exposed to; (ii) modulating activity of a BMP-15 dependent signalling pathway in the granulosa cell; and (iii) modulating activity of a BMP-6 dependent signalling pathway in a granulosa cell.

Abstract: Certain negative effects of medication overuse headache (MOH) are relieved by administering ibudilast or a pharmaceutically acceptable salt thereof.

Abstract: The invention describes a method and product for chelating micronutrients when used to provide the micronutrients to a plant, which comprises applying to an area of the plant or soil/substrate surrounding the plant an effective amount of a plant fertiliser composition comprising a chelating polymer having the general formula (I), capable of forming coordinate bonds with the micronutrients, transporting the micronutrients across a membrane of the plant and releasing the micronutrients for use by the plant.

Abstract: A method for estimating the activity topology of a set of sensed data windows is described. Each of the sensed data windows related to a corresponding sensed region. The method includes the steps of determining a subset of sensed data windows that are not connected; and excluding the subset of sensed data windows from the set of sensed data windows. In one embodiment, the sensed data windows corresponding to image windows such as would be provided by a visual surveillance system.

Abstract: A sensor based on optical fiber technology is described. The sensor includes an elongate core for propagating light having an excitation wavelength; an interaction region that includes a fluorescent material for excitation by the propagated light to produce fluorescent light; and an interface region defining a boundary between the elongate core and the interaction region. The elongate core of the sensor is adapted to increase an intensity of the propagated light at the interface region to increase the amount of captured fluorescent light in the elongate core.

Abstract: The present invention relates generally to transcriptional control sequences. Generally, the present invention relates to transcriptional control sequences that specifically or preferentially direct expression of a nucleotide sequence of interest in a plant egg cell. The present invention is predicated, in part, on the identification of transcriptional control sequences derived from EC1 genes which, in preferred embodiments, direct preferential expression in an egg cell of at least one plant taxon.

Abstract: The present invention relates generally to transcriptional control sequences for effecting expression of a nucleotide sequence of interest in a plant. The present invention is predicated, in part, on the identification and functional characterization of transcriptional control sequences derived from genes which encode polypeptides comprising the amino acid sequence set forth in SEQ ID NO: 1 and homologs thereof. Among other things, the present invention has identified that transcriptional control sequences derived from the subject genes can effect specific or preferential expression of an operably connected nucleotide sequence in a reproduction-associated plant part such as a seed or anther.

Abstract: According to the present invention, there is provided a method of sequestering micronutrients when used to provide the micronutrients to a plant, which comprises applying to an area of the plant or soil/substrate surrounding the plant an effective amount of a plant fertilizer composition comprising a surfactant, such as general formula (III), that is capable of forming coordinate bonds with micronutrients.

Abstract: The present invention relates to a method of comparing at least one chromosome or part thereof from a cell with a first karyotype with the corresponding chromosome or part thereof from a cell with a second karyotype.

Abstract: The present disclosure provides an optical detector for detecting radiation. The optical detector includes an optical light guide that incorporates a sensing region. The sensing region includes a sensing material that emits luminescence light when the sensing material is exposed to suitable ionizing radiation and accrues trapped charge which is released and produces optically stimulated luminescence (OSL) when the sensing material is optically stimulated. The optical detector also includes a light source for optically stimulating the sensing material and a light detector for detecting the OSL. The optical light guide is arranged to guide light through the sensing region and between the sensing region and the luminescence light detector.

Abstract: The present invention relates generally to transcriptional control sequences. Generally, the present invention relates to transcriptional control sequences that specifically or preferentially direct expression of a nucleotide sequence of interest in a plant egg cell. The present invention is predicated, in part, on the identification of transcriptional control sequences derived from EC1 genes which, in preferred embodiments, direct preferential expression in an egg cell of at least one plant taxon.

Abstract: The present invention is predicated on the discovery that a polysaccharide transferase purified from barley seedlings can catalyze the formation of covalent bonds between different polysaccharides, including between xyloglucans and cellulose, and between xyloglucans and (1,3;1,4)-?-D-glucans. The present invention thus provides, among other things, an isolated or substantially purified polysaccharide transferase, wherein said polysaccharide transferase is capable of catalyzing the formation of a covalent bond between a donor polysaccharide and an acceptor polysaccharide; or a functionally active fragment or variant of said polysaccharide transferase.

Abstract: A method and system for assessing the condition of a pipe carrying a fluid is disclosed. The method includes the steps of generating a pressure wave in the fluid being carried along the pipe and detecting a pressure wave interaction signal resulting from an interaction of the pressure wave with a localised variation in pipe condition. The method then involves determining from the timing of the pressure wave interaction signal the location of the localised variation in pipe condition and the extent of the localised variation in pipe condition based on a characteristic of the pressure wave interaction signal.

Abstract: A vineyard trellis system that includes a ground anchored upright post, at least one foliage wire passing by the post and having a supporting interengagement with the post, and lifting means arranged to effect a lifting or lowering of the wire in relation to the post where said lifting means include a support member slidably engaging with the post and engaging with the foliage wire, and a winch arrangement adapted to assist in a lifting or lowering of the support member to effect a change in height of the foliage wire with respect to the post.

Abstract: A method of forming a nanowire is disclosed. In one embodiment, a primary preform is formed comprising at least one central region and a support structure. The primary preform is then drawn to a cane, which is then inserted into an outer portion, to form a secondary preform. The secondary preform is then drawn until the at least one central portion is a nanowire. The method can produce nanowires of far greater length than existing methods, and can reduce the likelihood of damaging the nanowire when handling.

Abstract: A method of forming a nanowire is disclosed. In one embodiment, a primary preform is formed comprising at least one central region and a support structure. The primary preform is then drawn to a cane, which is then inserted into an outer portion, to form a secondary preform. The secondary preform is then drawn until the at least one central portion is a nanowire. The method can produce nanowires of far greater length than existing methods, and can reduce the likelihood of damaging the nanowire when handling.

Abstract: A sensor based on optical fiber technology is described. The sensor includes an elongate core for propagating light having an excitation wavelength; an interaction region that includes a fluorescent material for excitation by the propagated light to produce fluorescent light; and an interface region defining a boundary between the elongate core and the interaction region. The elongate core of the sensor is adapted to increase an intensity of the propagated light at the interface region to increase the amount of captured fluorescent light in the elongate core.