Patents Assigned to Advanced Neuromodulation Systems, Inc.
  • Patent number: 11135434
    Abstract: The present disclosure provides systems and methods for protection circuitry for an implantable pulse generator (IPG) of a neurostimulation system. The protection circuitry is coupled to an IPG ground, a plurality of electrodes, and an IPG case, and operable to protect IPG stimulation and sensing circuitry from damage during electrostatic discharge and cardiac defibrillation, and to mitigate unintended stimulation during electromagnetic interference. The protection circuitry includes an IPG ground connection, a plurality of protection Zener diodes, wherein one of the protection Zener diodes is electrically coupled between the IPG case and a float Zener diode, and wherein the remaining protection Zener diodes are electrically coupled between the plurality of electrodes and the float Zener diode, and the float Zener diode electrically coupled between the plurality of protection Zener diodes and the IPG ground.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: October 5, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Steven Boor
  • Patent number: 11135431
    Abstract: An implantable medical device (IMD) includes multiple stimulation engines for independently stimulating respective electrode sets of a lead system while avoiding collisions and/or channel contention during stimulation delivery. A first voltage multiplier is configured to generate an adjustable target voltage having sufficient headroom at an output node that is commonly coupled to anodic nodes of respective stimulation engines. Each stimulation engine includes a secondary voltage multiplier to drive the respective anode and a current regulator powered by a floating voltage supply, wherein the current regulator is coupled to a cathodic node and configured to control how much stimulation current is pulled from the patient tissue.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: October 5, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Daran DeShazo, Steven Boor
  • Patent number: 11135439
    Abstract: Embodiments are directed to an implantable medical device comprising therapeutic stimulation circuitry for controlling delivery of a medical therapy to a patient, the therapeutic stimulation circuitry having at least one lead having electrodes for delivering the medical therapy. The implantable medical device further comprises measurement circuitry for determining characteristics of the at least one lead, a processor for controlling the IMD according to executable code, and memory for storing data and executable code, wherein the executable code comprises instructions for causing the processor to receive a plurality of voltage measurements associated with the electrodes, and calculate values for an impedance model of the electrode/tissue interface.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: October 5, 2021
    Assignee: ADVANCED NEUROMODULATION SYSTEMS, INC.
    Inventors: Daran DeShazo, Steven Boor, Vidhi Desai
  • Patent number: 11133113
    Abstract: A system and method for facilitating remote care management involving a patient having an implantable medical device (IMD). Upon establishing a remote care session between a patient controller device and a clinician programmer, wherein the clinician and the patient are remotely located with respect to each other, input from the patient or the clinician may be received via a user interface control associated with a particular functionality or aspect of the remote care session, including audiovisual (AV) communications, remote therapy programming, and related context. Responsive to the user input, a dialog interface is effectuated at one of the patient controller device and/or the clinician programmer. A user characterization label is received via the dialog interface from the user, wherein the user characterization label is indicative of a subjective assessment of the particular functionality of the remote care session, which may be used in generating user-labeled data pertaining thereto.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: September 28, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Scott DeBates, Douglas Alfred Lautner, Tucker Tomlinson, James Nagle
  • Patent number: 11121624
    Abstract: A configurable multi-output charge pump for power supply generation includes one or more flying capacitors (FCs) arranged to be switchably connected into a plurality of circuit configurations operative to provide respective output voltages at a common charging node. A configuration logic circuit is operative to generate one or more configuration setting control signals to effectuate a particular circuit configuration. One or more storage capacitors (SC) are independently and individually connectable to the common charging node depending on a selection control logic having a configurable duty cycle, wherein each SC is operative to supply a respective voltage output to drive a corresponding electrical load.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: September 14, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Daran DeShazo
  • Publication number: 20210252291
    Abstract: An implantable medical device (IMD) includes multiple stimulation engines (SEs) for independently stimulating respective electrode sets of a lead system. A voltage multiplier (VM) is configured to generate an adjustable target voltage at an output node. Each stimulation engine includes first switching circuitry to switchably connect an anodic node of the SE to the VM output node and second switching circuitry to switchably connect a cathodic node of the SE to a current sink circuit. Discharge switching circuitry may be disposed between the anodic and cathodic nodes of each SE. A selector and associated digital control logic block are operative to generate control signals for independently controlling respective SEs such that each SE may be activated to stimulate or discharge a corresponding select set of electrodes independently from or in concert with remaining SEs.
    Type: Application
    Filed: February 13, 2020
    Publication date: August 19, 2021
    Applicant: Advanced Neuromodulation Systems, Inc.
    Inventors: Daran DeShazo, Steven Boor, Gavin L Rade
  • Patent number: 11090496
    Abstract: In one embodiment, an implantable medical device (IMD) comprises: therapeutic circuitry for controlling delivery of a medical therapy to a patient; a processor for controlling the IMD according to executable code; wireless communication circuitry for conducting wireless communications; and memory for storing data and executable code, wherein the executable comprises code for causing the processor to (1) communicate with an external programming device to define therapeutic settings for operation of the IMD, (2) perform validation operations on one or more instances of therapeutic settings by determining whether a respective instance of therapeutic settings is accompanied by permanent validation data or temporary validation data, wherein the validation operations comprise analyzing temporary validation data against at least one key of a plurality of cryptographic keys stored by the IMD.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: August 17, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Christopher S. L. Crawford
  • Publication number: 20210244948
    Abstract: A system and method for extracting ETI load parametric data relative to one or more electrodes of an implanted stimulation lead system associated with an IPG. A Kelvin connection scheme is provided for measuring induced voltages present at stimulated electrodes during a stimulation ramping sequence, which may be used for determining the ETI parametric data using a number of techniques, including, without limitation, a waveform analysis.
    Type: Application
    Filed: February 6, 2020
    Publication date: August 12, 2021
    Applicant: Advanced Neuromodulation Systems, Inc.
    Inventors: Daran DeShazo, Steven Boor
  • Patent number: 11083900
    Abstract: In one embodiment, a method for operating a system for management of implantable medical devices (IMDs), comprises: conducting communication sessions with a plurality of clinician programmer devices while the clinician programmer devices are engaged in respective programming sessions with IMDs; receiving and storing second programming data from a plurality of clinician programmer devices, wherein the second programming data was created during programming sessions with IMDs without network connectivity to the system for management of IMDs; reconciling programming of the plurality of IMDs that were programmed with the second programming data with data stored by the system for management of IMDs; and communicating second signed validation data to cause IMDs to conduct therapeutic operations according to programming data validated by respective instances of second validation data.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: August 10, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Christopher S. L. Crawford
  • Publication number: 20210236822
    Abstract: An implantable medical device (IMD) includes multiple stimulation engines for independently stimulating respective electrode sets of a lead system while avoiding collisions and/or channel contention during stimulation delivery. A first voltage multiplier is configured to generate an adjustable target voltage having sufficient headroom at an output node that is commonly coupled to anodic nodes of respective stimulation engines. Each stimulation engine includes a secondary voltage multiplier to drive the respective anode and a current regulator powered by a floating voltage supply, wherein the current regulator is coupled to a cathodic node and configured to control how much stimulation current is pulled from the patient tissue.
    Type: Application
    Filed: January 31, 2020
    Publication date: August 5, 2021
    Applicant: Advanced Neuromodulation Systems, Inc.
    Inventors: Daran DeShazo, Steven Boor
  • Patent number: 11071864
    Abstract: An apparatus and method for providing split stimulation currents in a pulse generator. In one embodiment, a current regulator of the pulse generator includes a digitally-programmable analog voltage generator coupled to a first input of an error amplifier that receives a second input controlled by a programmable resistor network configured to control a programmable total stimulation current output. A plurality of current splitting switches are operative to split the programmable total stimulation current output into a corresponding plurality of split current segments, which may be individually mapped to a selected set of lead electrodes across one or more implantable leads associated with the pulse generator.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: July 27, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Steven Boor, Daran DeShazo
  • Patent number: 11065449
    Abstract: Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy are disclosed. In one embodiment, a system and/or method may apply electromagnetic stimulation to a patient's nervous system over a first time domain according to a first set of stimulation parameters, and over a second time domain according to a second set of stimulation parameters. The first and second time domains may be sequential, simultaneous, or nested. Stimulation parameters may vary in accordance with one or more types of duty cycle, amplitude, pulse repetition frequency, pulse width, spatiotemporal, and/or polarity variations. Stimulation may be applied at subthreshold, threshold, and/or suprathreshold levels in one or more periodic, aperiodic (e.g., chaotic), and/or pseudo-random manners. In some embodiments stimulation may comprise a burst pattern having an interburst frequency corresponding to an intrinsic brainwave frequency, and regular and/or varying intraburst stimulation parameters.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: July 20, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Bradford Evan Gliner, Allen Wyler, Brad Fowler, W. Douglas Sheffield, Richard Kuntz, Kent Leyde, Leif R. Sloan
  • Patent number: 11033733
    Abstract: In one embodiment, a method for fabricating a neurostimulation stimulation lead comprises: providing a plurality of ring components and hypotubes in a mold; placing an annular frame with multiple lumens over distal ends of the plurality of hypotubes to position a portion of each hypotube within a respective lumen of the annular frame; molding the plurality of ring components and the hypotubes to form a stimulation tip component for the stimulation lead, wherein the molding fills interstitial spaces between the plurality of ring components and hypotubes with insulative material; and forming segmented electrodes from the ring components after performing the molding.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: June 15, 2021
    Assignee: ADVANCED NEUROMODULATION SYSTEMS, INC.
    Inventors: Ryan Sefkow, Christopher A. Crawford, Jeffrey Mitchell, Kevin Wilson, Raymond P. Bray, John R. Gonzalez
  • Patent number: 11033732
    Abstract: In some embodiments, a clinician programmer device for controlling a deep brain stimulation (DBS) system is adapted to assist a clinician to conduct an electrode screening review for the DBS system including screening of segmented electrodes. The clinician programmer stores software code for conducting a screening review in memory. The software code may comprise: code for providing one or more interface screens for guiding the user of the device through testing of electrode configurations of the implantable stimulation lead, wherein the code for providing applies at least one testing progression for guiding the user of the device through a defined testing order.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: June 15, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventors: Binith J. Cheeran, Jonathan P. Avedikian, Brittany L. Boudreau, Jason Pounds
  • Patent number: 10967190
    Abstract: In one embodiment, a method for operating a system for management of implantable medical devices (IMDs), comprises: conducting communications sessions with a plurality of clinician programmer devices, wherein some of the communication sessions occur while the plurality of clinician programmer devices are engaged in respective programming sessions with IMDs; conducting communications sessions with a plurality of patient controller devices, wherein the communication sessions with the patient controller devices include communication of data pertaining to offline programming of IMDs; reconciling programming session data received from the plurality of clinician programmer devices with programming session data received from patient controller devices to identify instances of unauthorized IMD programming; and distributing revocation data to patient controller devices to be downloaded to corresponding IMDs, wherein the revocation data identifies cryptographic keys that are no longer trusted.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: April 6, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Christopher S. L. Crawford
  • Patent number: 10946199
    Abstract: A neurostimulation system (NS) includes an array of electrodes positioned within a patient with an active cathode electrode located proximate to target neural tissue. A control circuit is controls delivery of therapy during a therapy delivery interval, with the therapy being delivered between an anode electrode and the active electrode. A current regulator circuit (CRC) is connected to the cathode electrode and controls current flow through the cathode electrodes. The control circuit manages the CRC to control a discharge current flow over the discharge operation to discharge developed residual voltage between the anode electrode and the active electrode in a manner that follows an actively emulated passive discharge (AEPD) profile. During the discharge operation, the CRC is connected to the inactive electrode, and receives, as a first input, an EMI feedback signal.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: March 16, 2021
    Assignee: ADVANCED NEUROMODULATION SYSTEMS, INC.
    Inventors: Steven Boor, Daran DeShazo
  • Patent number: 10933231
    Abstract: Disclosed herein is a lead insertion tool for inserting a lead connector end of an implantable lead into a lead receptacle of a header of an implantable pulse generator, the implantable lead including a lead body extending distally from the lead connector end. The tool includes a lead pathway and an engagement mechanism. The lead pathway extends through the tool and is configured to receive the implantable lead. The engagement mechanism includes an engaged state and a self-biasing non-engaged state. When the engagement mechanism is self-biased into the non-engaged state, the implantable lead is free to displace along the lead pathway. When the engagement mechanism is forced into the engaged state, the lead cannot displace along the lead pathway.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: March 2, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Aaron Raines
  • Patent number: 10894166
    Abstract: A multi-lead stimulation lead connector for facilitating electrical and mechanical connectivity between one or more stimulation leads and a pulse generator, e.g., an EPG used in a test stimulation system. One or more cam lock assemblies are disposed in a housing, each cam lock assembly comprising a cam knob and a cam shaft and having a longitudinal channel defined therein for accepting a proximal end of a respective stimulation lead, the proximal end having a plurality of terminal contact electrodes. By actuating a rotational movement of the cam knob, the cam lock assembly is unlocked in a first direction for guiding the proximal end and locked in a second direction for securely holding the proximal end and effectuating electrical connectivity with a plurality of conductors encapsulated in a cable for interfacing with the EPG.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: January 19, 2021
    Assignee: Advanced Neuromodulation Systems, Inc.
    Inventor: Aaron Raines
  • Patent number: 10894159
    Abstract: The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a combination of burst and tonic stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: January 19, 2021
    Assignee: ADVANCED NEUROMODULATION SYSTEMS, INC.
    Inventor: Dirk De Ridder
  • Patent number: 10792502
    Abstract: The systems and methods described herein generally relate to adjusting a neurostimulation (NS) therapy based on drug pharmacokinetics of a patient. The systems and methods deliver an NS therapy to a portion of electrodes of a lead positioned proximate to neural tissue of interest, which is associated with a target region. The NS therapy is defined by stimulation parameters. The systems and methods determine a trigger event indicative of a drug being administered to a patient. The drug is configured to affect at least one of the neural tissue of interest or the target region. The systems and methods adjust one or more of the stimulation parameters based on the PS profile.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: October 6, 2020
    Assignee: ADVANCED NEUROMODULATION SYSTEMS, INC.
    Inventor: Filippo Agnesi