Abstract: An antenna array for use within a microwave imaging system to capture a microwave image of a target is selectively programmed to optimize one or more parameters of the microwave imaging system. The array includes a plurality of antenna elements, each capable of being programmable with a respective phase shift to direct a beam of microwave radiation toward the target such that the microwave radiation from each of the plurality of antenna elements arrives at the target substantially in-phase. To optimize a parameter of the microwave imaging system, the phase shifts of selective ones of the antenna elements are altered, while still maintaining the substantially in-phase microwave radiation at the target.

Abstract: Systems, methods and computer readable storage media for displaying a dense graph and details of a portion of the dense graph on a display are provided. A processor coupled to memory, an input device and a display are provided to perform operations including: locally distorting a portion of the dense graph identified by interaction through the input device, wherein the local distortion includes expanding the portion of the dense graph along a first dimension axis of the graph, compressing at least one adjacent portion of the dense graph adjacent the expanded portion, and maintaining a scale of all of the dense graph in a second dimension orthogonal to the first dimension. The dense graph and expanded and compressed portions are displayed on the display, wherein all of the graph represented by the display signal on the display prior to performing the local distortion operation is displayed after performing the local distortion operation. In at least one embodiment, the system comprises an oscilloscope.

Abstract: The invention relates to the generation and characterization of Archaeal DNA polymerase mutants with deficient 3?-5? exonuclease activity and reduced base analog detection activity. The invention further provides for Archaeal DNA polymerase mutants with deficient 3?-5? exonuclease activity and reduced base analog detection activity containing additional mutations that modulate other DNA polymerase activities including DNA polymerization or reverse transcriptase activity. The invention also discloses methods and applications of DNA polymerases with deficient 3?-5? exonuclease activity and reduced base analog detection activity.

Abstract: A fluidic chip device configured for processing a fluidic sample includes two outer boundary layers, and at least one reinforcing layer arranged between the two outer boundary layers and being at both of its opposing main surfaces laminated with directly adjacent layers to reinforce pressure resistance of the fluidic chip device by the lamination, in which at least a part of the layers of the fluidic chip device includes a hole forming at least a part of a fluidic conduit for conducting the fluidic sample under pressure.

Abstract: A method for preparing functionalized porous particles is disclosed, the method comprising contacting a plurality of porous silica particles with water, at least one of an ionic fluoride such as HF or NH4F or a basic activator, and a multifunctional organosilane. Also disclosed are functionalized porous silica particles produced from the methods disclosed herein.

Abstract: A fluidic device (100) comprising a substrate (101) and a transport medium (103) provided on the substrate (101) to define a transport path for transporting a fluidic sample (104) driven by an electric force.

Abstract: A thermal modulation device for a gas chromatography (GC) system a cold zone, a first hot zone and a second hot zone, which are located outside of a GC oven of the GC system, and a flexible capillary column. The cold zone includes a thermoelectric cooler assembly. The first hot zone is adjacent a first side of the cold zone, and has a corresponding first heat source. The second hot zone is adjacent a second side of the cold zone, and has a corresponding second heat source. The flexible capillary column includes a first segment, configured to move between the first hot zone and the cold zone in accordance with a modulation frequency, and a second segment, configured to move between the cold zone and the second hot zone in accordance with the modulation frequency.

Abstract: A method and system of providing a phase reference signal includes generating a reference signal having a reference frequency, modulating the reference signal at a modulation frequency lower than the reference frequency to obtain a modulated drive signal, receiving the modulated drive signal at a phase reference, and generating the phase reference signal based on the modulated drive signal. The phase reference signal including multiple reference tones having corresponding tone frequencies clustered around multiples of the reference frequency. A spacing between adjacent tones of the multiple reference tones is the same as the modulation frequency or an integer multiple of the modulation frequency.

Abstract: A signal bus includes multiple interconnects for transporting electronic signals. The interconnects have different physical path lengths and different structures to equalize the different the physical path lengths, so that the electronic signals traverse the corresponding interconnects in same period of time.

Abstract: Aspects of the invention include 2? protected nucleoside monomers that are protected at the 2? site with thiocarbon protecting groups. Thiocarbon protecting groups of interest include thiocarbonate, thionocarbonate, dithiocarbonate groups, as well as thionocarbamate protecting groups. Aspects of the invention further include nucleic acids that include the protecting groups of the invention, as well as methods of synthesizing nucleic acids using the protecting groups of the invention.

Abstract: An apparatus and method for determining if ringing in an output signal from a receiver that processes an input signal is the result of a bandwidth limitation in the receiver that processes an input signal rather than ringing in the input signal is disclosed. The apparatus includes the receiver and a ring suppression filter. The ring suppression filter receives the receiver output signal and generates a ring suppressed output signal therefrom. The receiver and the ring suppression filter provide a first aggregate system response such that the ring suppressed output signal does not include ringing introduced by the receiver. The first aggregate system response is linear in phase.

Abstract: The invention features a novel isolated Family B DNA polymerase, a Thermococcus polymerase JDF-3, and mutant recombinant forms thereof. Mutant polymerases of the invention are deficient in 3? to 5? exonuclease activity and/or exhibit reduced discrimination against non-conventional nucleotides relative to the wild-type form of the polymerase.

Abstract: A valve arrangement is disclosed for providing a switchable fluid connection between a fluid delivery system for driving a mobile phase and a stationary phase adapted for separating compounds of a sample fluid comprised in the mobile phase.

Abstract: A contactless device for measuring at least the temperature of a rotor of a high-speed rotary machine, in particular a turbomolecular vacuum pump, comprises at least one magnetic capsule mounted on the rotor of the pump. The capsule comprises a permanent magnet and at least one pastille of ferromagnetic material having a Curie temperature slightly higher than a maximum temperature to be measured. The magnetic permeability of this material strongly depends on temperature. The pastille is intended to alter the magnetic field generated by the magnet. A detector carried by the stator of the pump generates pulses representative of the magnetic field varying with the rotor temperature, generated by the capsule, whenever the latter passes in front of the detector.

Abstract: A method for controlling operation of a pump unit, where the pump unit includes a primary piston pump having a primary piston and a secondary piston pump having a secondary piston. The primary piston pump is fluidically connected with the secondary piston pump. The primary piston pump includes an inlet valve and an outlet valve, and the pump unit operates periodically according to a pump cycle. The method includes determining a fluid pressure of fluid dispensed by the pump unit, and performing a closed loop control of a position of the primary piston in dependence on the fluid pressure of the fluid dispensed by the pump unit during a first time interval of the pump cycle.

Abstract: The present invention provides a method for detecting or enriching for a target deoxyribonucleic acid (DNA) present in a nucleic acid sample, said method comprising: (a) fragmenting a nucleic acid sample to generate nucleic acid fragments including a target fragment containing said target DNA; (b) rendering said fragments, including said target fragment, at least partially single-stranded, wherein the single-stranded portion includes an end portion and wherein the length of said single-stranded portion is sufficient to allow hybridisation of at least part of the single-stranded portion of said target fragment to the probe of step (c); (c) contacting the at least partially single-stranded fragments of step (b) with oligonucleotides A and B of a single target-specific nucleic acid probe, wherein: (i) oligonucleotide A is a single-stranded oligonucleotide comprising at one end a first target-specific part comprising at least 10 nucleotides complementary in sequence to at least part of said single-stranded portio

Abstract: A coupling device includes a fiber collimator, a wedge window pair and a plane window for coupling a light beam provided by a beam source to optical fiber. The fiber collimator is mounted to a base plate and includes a collimator lens, an end of the optical fiber being positioned at a focal point of the collimator lens. The wedge window pair is mounted to the base plate, and is configured to adjust the light beam to be parallel to an optical axis of the fiber collimator. The plane window is mounted to the base plate between the wedge window pair and the fiber collimator. The plane window is configured to align the parallel direction of the light beam with the optical axis of the fiber collimator.

Abstract: A nuclear magnetic resonance (NMR) probe circuit assembly includes one or more probe circuits in signal communication with one or more respective sample coils configured for transmitting and/or receiving radio-frequency (RF) energy to and/or from a sample of interest. One or more of the probe circuits have a suspended substrate configuration in which variable capacitors share a common dielectric substrate that is separated from a ground plane by an air gap. Each variable capacitor includes an electrode that is movable by a user-actuated adjusting device. One or more of the probe circuits may have a multiply resonant or broadband configuration, and may have one or more individual channels. One or more of the variable capacitors enable tuning to resonant frequencies of selected nuclei. One or more other variable capacitors may enable impedance matching.

Abstract: Aspects of the invention include 2? protected nucleoside monomers that are protected at the 2? site with orthoester-type protecting groups. The 2? protected monomers also include a second, aryl carbonate-type, protecting group. Aspects of the invention further include nucleic acids that include the protecting groups of the invention, as well as methods of synthesizing nucleic acids using the protecting groups of the invention.

Abstract: An apparatus includes a global synchronization interface and multiple modules. The global synchronization interface includes a global synchronization driver for driving a global synchronization signal. The modules include corresponding local synchronization interfaces, each local synchronization interface having a local synchronization driver for driving a local synchronization signal. In a local mode, the modules ignore the global synchronization signal and synchronize corresponding operations according to the local synchronization signal and a global reference signal. In a global mode, the modules ignore the local synchronization signal and synchronize the corresponding operations according to the global synchronization signal and the global reference signal.