Abstract: A method for operating a data processing system having a touch enabled display screen that displays a plurality of waveforms to alter the display of one of the waveforms without altering the display of the remaining waveforms is disclosed. The method includes determining a selected waveform in response to a user touching the display screen in a first location thereby defining a touch area that determines the selected waveform. An operation that is to be performed on the selected waveform is then defined by a gesture on the screen. The selected waveform is determined by a touch area that is defined by the user touching the screen. If more than one waveform is defined by the touch area, the possible waveforms are sequentially selected until the correct one is presented to the user in response to the user repeating the touching that defines the touch area.

Abstract: An apparatus for holding a contact lens during in vitro testing includes a first support member, a second support member, an alignment rod, and a cage member. The first support member includes a first end cap and a body portion. The body portion includes grooves formed in a lateral surface extending from the first end cap. The alignment rod is configured for interconnecting the body portion and a second end cap of the second support member. The cage member is positionable about the body portion between the first and second end caps, and includes an inner surface, an outer surface, and a plurality of openings between the inner surface and the outer surface. The inner surface and the lateral surface cooperatively define an annular space therebetween and a plurality of fluid flow paths between the inner space and the openings. The annular space is configured for receiving the contact lens.

Abstract: A method of generating a trend graph comprises storing a stream of data elements in a buffer having a storage capacity corresponding to a first number of data elements, compressing the stored data elements to fit within a display having a size corresponding to a second number of data elements smaller than the first number of data elements, detecting an event, and as a consequence detecting the event, compressing the stored data elements to occupy a reduced portion of the buffer.

Abstract: Provided herein is method comprising: contacting an initial RNA sample containing a population of different RNA molecules with a divalent cation and a set of DNAzymes that are designed to cleave multiple target RNAs in the initial sample, thereby producing a product RNA sample that comprises: a) uncleaved RNA molecules and b) cleaved RNA fragments that contain a 2?,3?-cyclic-phosphate and a 5? hydroxyl as the result of DNAzyme cleavage.

Abstract: A measurement instrument receives an analog input signal from a measurement target, converts the input signal into a digital signal, scans the digital signal and comparing the scanned digital signal with a pattern signature using a flexible matching procedure implemented by hardware, and triggers the measurement instrument according to a result of the flexible matching procedure.

Abstract: An apparatus comprises a proportional valve, a first channel connected to the proportional valve, a flow sensor connected to the first channel and configured to measure gas flow in the first channel, a split channel connected to the first channel at a location between the proportional valve and the flow sensor, and a control component connected between the flow sensor and the proportional valve and configured to control gas flow in the first channel.

Abstract: A device includes a memory storing a persistence bit for each of a plurality of pixels of a display device, the persistence bit having a first value when a corresponding pixel should be illuminated for displaying a persistent image, and having a second value when the corresponding pixel should not be illuminated for the persistent image; a pseudorandom pixel value generator which during each video frame receives a seed value and generates pseudorandom pixel values for the plurality of pixels, each pseudorandom pixel value being not greater than a specified variable persistence value; a frame value generator outputting a frame value for each video frame; and a match detector which, during each video frame, compares the frame value to the pseudorandom pixel values for the plurality of pixels, and for each pixel where the comparison indicates a match, makes the persistence bit for the corresponding pixel have the second value.

Abstract: The present invention relates to an improved system for efficiently and accurately performing immunoassays, such as ELISAs. The invention provides an immunoassay assembly which includes a flow-through unit and an aspiration pump. The immunoassay flow-through unit includes an outer seal; at least one bed support; an inner seal; and a packed non-porous bed. The unit is releasably attached to an aspiration pump which enables the controlled flow rate of liquid passing through the packed bed of the flow-through unit. The invention also provides a method of using the immunoassay assembly to identify analytical targets of interest.

Abstract: A method of determining the mass-to-charge ratios of ions in a sample is disclosed. The method includes determining a data acquisition time, where the data acquisition time is a predetermined fraction of the greatest time of flight. The method also includes providing ions from a continuous beam of a sample to a time-of-flight mass analyzer at pulse intervals having a duration equal to the predetermined fraction of the greatest flight time. The method also includes measuring a peak width and a flight time value for each of the ion species in the sample after summing the data acquired during several pulse intervals and correcting the measured flight time values according to a correlation of measured peak width values with calibration data of peak width versus flight time.

Abstract: Pipette tips of different sizes may be coupled to a pipettor without needing to modify the pipettor. The same pipettor may thus be utilized to exchange different pipette tips, which may be done in an automated manner. Pipette tips may be coupled to adaptors that include proximal ends for interfacing with the pipettor and distal ends for interfacing with pipette tips. The proximal ends may all have the same geometry, matched with the same pipettor. The distal ends may have different geometries matched with different pipette tips. A pipettor may be part of a liquid handling apparatus and movable in an automated manner to different deck positions. The pipettor may include a locking mechanism for locking adaptors to the pipettor or locking pipette tips directly to the pipettors, and an ejection mechanism for ejecting pipette tips from corresponding adaptors.

Abstract: Provided herein are systems and method for using unit mass library searches for sample identification in accurate mass spectrometry. In general, the systems and methods described herein: (a) obtain an accurate mass spectrum of a sample; (b) calculate a unit mass spectrum based on the accurate mass spectrum; and (c) conduct a unit mass library search, based on the calculated unit masses, to obtain at least one candidate species to thereby identify the sample. The systems and methods may further: (d) calculate exact masses for each of a plurality of candidate species; and (e) eliminate candidate species due to ions that are outside a mass error window. The mass error window may be less than 500 ppm. The system and methods presented may be used in, for example, gas chromatrography mass spectrum and/or liquid chromatography mass spectrometry systems.

Abstract: A transverse volume magnetic resonance (MR) coil includes a cylindrical geometry of electrical conductors configured for generating a B1 field comprising nth mode spatial harmonics along a first transverse axis in a transverse plane orthogonal to a central axis of the coil, while being uniform along a second transverse axis orthogonal to the first transverse axis in the transverse plane, where n is an integer ranging from 1 or greater. The coil may be included with other coils in an array coil. The coil may be utilized to detect geometric echoes resulting from excitation of an MR sample.

Abstract: In a vibration damper of a turbomolecular vacuum pump, a vacuum tightness function and a vibration damping function are both performed by one or more toroidal rings made of an elastic material. The elastic rings assume a resting configuration while the vacuum pump is not operating and the damper is at atmospheric pressure, and they assume a compressed configuration while the vacuum pump is operating and the damper is under vacuum conditions. In the compressed configuration, the elastic rings are deformed due to a compression force. This deformation of the elastic rings prevents metal-to-metal contact between the vacuum pump and a vacuum chamber to which the pump is connected through the damper.

Abstract: A method for operating a display in a data processing system to provide a view of a portion of a data array on a display screen is disclosed. The method includes providing a first display window characterized by a first offset, a first horizontal gain, and a first vertical gain and receiving a feature input from a user indicating a selected feature in the first display window. The data processing system automatically provides a second display window characterized by a second offset and a second horizontal gain and a second vertical gain. The second offset, the second horizontal gain and the second vertical gain are chosen such that the feature is at a predetermined location in the second display window and the second horizontal gain and second vertical gain are chosen such that the selected feature occupies a predetermined portion of the second display window.

Abstract: A method of operating a first data processing system having a screen for responding to a vector gesture performed on that screen is disclosed. The method includes estimating a direction and assuming an identity for the vector gesture prior to the vector gesture being completed. A command that depends on the estimated direction and assumed identity is executed, the command being a command that would be required to update a current state of the first data processing system if the assumed identity of the vector gesture is correct. The command is executed prior to the vector gesture being completed. The current state of the first data processing system is then updated based on the data generated by the command. After the vector gesture has been determined to have been completed, the first data processing system is updated to a state indicated by the completed vector gesture.

Abstract: Provided herein is a proximity assay that, in certain embodiments, involves: (a) hybridizing a first oligonucleotide and a second oligonucleotide with a target nucleic acid, wherein the first oligonucleotide comprises: i. a region that is complementary to a first sequence in the target nucleic acid and ii. a barcode sequence; and the second oligonucleotide comprises i. a region that is complementary to a second region in the target and ii. the complement of the barcode sequence; and (b) detecting hybridization between the barcode sequence and the complement of the barcode sequence, wherein hybridization between the barcode sequence and the complement of the barcode sequence indicates that the first and second target sequences are proximal to one another in the sample.

Abstract: Non-rigid tape apparatus and fabrication methods for microfluidic processing applications such as gel electrophoresis are provided, where microfluidic processing is performed on selected areas. Parts of the tape are formed by high pressure plastic film forming. Membranes and other structures are self sealing during and after penetration by pipettes and electrical probes. Rigid exoskeleton elements protect the non-rigid parts during processing and facilitate transport of the tape.

Abstract: An apparatus and technique that reduces induced cross-talk current between transformer windings. The apparatus includes a transformer having a first secondary winding that provides a first voltage relative to earth ground, a second secondary winding that provides a second voltage relative to floating ground, and a shield disposed between the first and second secondary windings. A correction circuit connected to the first secondary winding is configured to generate a correction voltage. The correction voltage drives a shield to induce a correction current into the second secondary winding to reduce cross-talk current induced between the first and second secondary windings.

Abstract: A real-time spectrum analyzer for measuring time domain data sampled from an input signal includes a processing unit and a density histogram memory unit. The processing unit includes an FFT engine, a frequency mask detector and a frequency mask gate. The FFT engine performs FFTs on the sampled time domain data to provide FFT spectra, each FFT spectrum including multiple FFT points. The frequency mask detector determines whether each FFT point in each spectrum meets a trigger condition, and generates gate control signals corresponding to the FFT spectra based on the determinations. The frequency mask gate receives the FFT spectra and the gate control signals, and outputs only select FFT spectra that contain at least one FFT point that meets the trigger condition in response to the corresponding gate control signal. The density histogram memory unit stores the select FFT spectra for generating in a density histogram.

Abstract: A method of operating an electronic system comprises storing information corresponding to an input data stream in a first memory having a first operating rate, detecting an overflow condition of the first memory, generating overflow information in response to the detection of the overflow condition, storing the overflow information in a second memory having a second operating rate slower than the first operating rate, transferring the overflow information from the detector to a third memory at a first transfer rate corresponding to the first operating rate, temporarily storing the overflow information in the third memory, and transferring the stored overflow information to the second memory at a second transfer rate corresponding to the second operating rate, and combining the information stored in the first memory with the overflow information stored in the second memory to produce an output data stream.