Patents Assigned to AiCuris GmbH & Co. KG
  • Heterocyclylamide-substituted thiazoles, pyrroles and thiophenes
    Patent number: 8410090
    Abstract: The invention relates to heterocyclylamide-substituted thiazoles, pyrroles and thiophenes and processes for their preparation, to pharmaceutical compositions containing them, and to their use for the treatment and/or prophylaxis of diseases, in particular for the use as antiviral agents, especially against cytomegaloviruses.
    Type: Grant
    Filed: July 1, 2006
    Date of Patent: April 2, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Holger Zimmermann, David Brueckner, Kerstin Henninger, Martin Hendrix, Martin Radtke
  • SOLID DISPERSION COMPRISING AN ANTI-HIV AGENT
    Publication number: 20130072531
    Abstract: The present invention relates to solid dispersions comprising a compound of formula or a salt, a solvate or a solvate of a salt thereof, dispersed in a polymeric, inert, non-toxic, pharmaceutically acceptable excipient.
    Type: Application
    Filed: March 9, 2012
    Publication date: March 21, 2013
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Ellen VERHOEVEN, Jody Voorspoels, Yves Gonnissen, Yves Ruysschaert
  • Substituted (pyrazolylcarbonyl)imidazolidinones and their use
    Patent number: 8399682
    Abstract: The present invention relates to novel substituted (pyrazolylcarbonyl)imidazolidinones, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: March 19, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • SUBSTITUTED (THIAZOLYL-CARBONYL)IMIDAZOLIDINONES AND USE THEREOF
    Publication number: 20130045999
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: February 17, 2012
    Publication date: February 21, 2013
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Kersten Matthias Gericke, Steffen Wildum, Daniela Paulsen
  • Process for the preparation of dihydroquinazolines
    Patent number: 8372972
    Abstract: The present invention relates to a process for the preparation of dihydroquinazolines, for example, methyl (S)-{8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoro -methyl)-phenyl]-3,4-dihydroquinazolin-4-yl}acetate (2S,3S)-2,3-bis[(4-methylbenzoyl) -oxy]succinic acid salt, which are used for the production of antiviral medicaments.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: February 12, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Käthe Gooβen, Oliver Kuhn, Mathias Berwe, Joachim Kruger, Hans-Christian Militzer
  • Recombinant proteins of parapoxvirus ovis and pharmaceutical compositions therefrom
    Patent number: 8357363
    Abstract: The invention relates to polynucleotides coding for the PPVO viral genome, to fragments of the polynucleotides coding for the PPVO genome and to polynucleotides coding for individual open reading frames (ORFs) of the PPVO viral genome. The invention also relates to recombinant proteins expressed from the above mentioned polynucleotides and to fragments of said recombinant proteins, and to the use of said recombinant proteins or fragments for the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: January 22, 2013
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Olaf Weber, Sonja Maria Friederichs, Angela Siegling, Tobias Schlapp, Andrew Allan Mercer, Stephen Bruce Fleming, Hans-Dieter Volk
  • Heterocyclyl-substituted dihydroquinazolines and their use as antiviral agents
    Patent number: 8343981
    Abstract: The invention relates to heterocyclyl-substituted dihydroquinazolines of formula (I), to processes for their preparation, to medicaments containing them, and to methods for the treatment and/or prophylaxis of diseases, in particular, for use as anti-viral agents, in particular, against cytomegaloviruses.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: January 1, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Tobias Wunberg, Judith Baumeister, Mario Jeske, Peter Nell, Susanne Nikolic, Frank Suessmeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Joerg Keldenich, Dieter Lang
  • Parapoxviruses in combination with other antiviral agents for the treatment of viral diseases
    Patent number: 8343478
    Abstract: The present invention relates to the use of Parapoxviruses in combination with other agents for the treatment of viral diseases, and in particular HIV infections and AIDS. The invention also relates to methods for producing medicaments based on combinations of Parapoxviruses and other antiviral agents, and to such medicaments. In particular, the invention relates to the use of Parapoxviruses in combination with agents of the kind used for antiretroviral therapy and highly active antiretroviral therapy (HAART).
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: January 1, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Daniela Paulsen, Helga Ruebsamen-Schaeff, Amar Kureishi, Gerhard Hunsmann, Christiane Stahl-Hennig, Andreas Meyerhans, Alexandra Schuetz, Olaf Weber
  • Substituted furancarboxamides, and use thereof
    Patent number: 8324268
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: December 4, 2012
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • Substituted arylsulfonamides as antiviral agents
    Patent number: 8318761
    Abstract: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: November 27, 2012
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Niels Svenstrup, Holger Zimmermann, Dagmar Karthaus, Andreas Goeller, Dirk Heimbach, Kerstin Henninger, Dieter Lang, Daniela Paulsen, Bernd Riedl, Rudolf Schohe-Loop, Joachim Schuhmacher, Tobias Wunberg
  • Substituted pyrazolamides and their use
    Patent number: 8314089
    Abstract: The present invention relates to novel substituted pyrazolamides, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: November 20, 2012
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Rudolf Schohe-Loop, Reinhold Welker, Arnold Paessens, Marcus Bauser, Friederike Stoll, Frank Dittmer, Kerstin Henninger, Daniela Paulsen, Dieter Lang
  • Substituted dihydroquinazolines II
    Patent number: 8314113
    Abstract: The invention relates to substituted dihydroquinazolines and to a method for the production thereof, the use thereof for treating and/or preventing diseases and for producing drugs for treating and/or preventing diseases, in particular for the use of the inventive dihydroquinazolines in the form of antiviral agents, in particular against cytomegaloviruses.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: November 20, 2012
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Tobias Wunberg, Judith Baumeister, Mario Jeske, Peter Nell, Susanne Nikolic, Frank Suessmeier, Holger Zimmermann, Rolf Grosser, Guy Hewlett, Jorg Keldenich, Dieter Lang, Kerstin Henninger
  • Substituted azaquinazolines having an antiviral action
    Patent number: 8198282
    Abstract: This invention relates to substituted azaquinazolines, to a process for their preparation, to pharmaceutical compositions containing them, and to their use for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, in particular against cytomegaloviruses.
    Type: Grant
    Filed: December 24, 2009
    Date of Patent: June 12, 2012
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Tobias Wunberg, Judith Baumeister, Mario Jeske, Frank Suessmeier, Holger Zimmermann, Kerstin Henninger, Dieter Lang
  • PROCESS FOR THE PREPARATION OF DIHYDROQUINAZOLINES
    Publication number: 20120130072
    Abstract: The present invention relates to a process for the preparation of dihydroquinazolines, which are used for the production of medicaments.
    Type: Application
    Filed: November 30, 2011
    Publication date: May 24, 2012
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kãthe Gooßen, Oliver Kuhn, Mathias Berwe, Joachim Krüger, Hans-Christian Militzer
  • SUBSTITUTED (THIOPHENYL-CARBONYL)IMIDAZOLIDINONES, AND USE THEREOF
    Publication number: 20120022123
    Abstract: The present invention relates to novel substituted (thiophenyl-carbonyl)imidazolidinones, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: June 16, 2011
    Publication date: January 26, 2012
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai THEDE, Susanne GRESCHAT, Steffen WILDUM, Daniela PAULSEN
  • SUBSTITUTED FURANCARBOXAMIDES, AND USE THEREOF
    Publication number: 20120022059
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: June 16, 2011
    Publication date: January 26, 2012
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai THEDE, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • Process for the preparation of dihydroquinazolines
    Patent number: 8084604
    Abstract: The present invention relates to a process for the preparation of dihydroquinazolines, for example {8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl}acetic acid, which are used as antiviral agents in the production of medicaments.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: December 27, 2011
    Assignee: Aicuris GmbH & Co., KG
    Inventors: Käthe Gooβen, Oliver Kuhn, Mathias Berwe, Joachim Krüger, Hans-Christian Militzer
  • Lysobactin amides
    Patent number: 8076285
    Abstract: The invention relates to lysobactin amides and methods for their preparation, as well as their use for manufacturing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infectious diseases.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: December 13, 2011
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Franz Von Nussbaum, Hartmut Beck, Nina Brunner, Rainer Endermann, Johannes Koebberling, Jacques Ragot, Joachim Telser, Joachim Schuhmacher, Sonja Anlauf, Yolanda Cancho-Grande, Susanne Greschat, Hans-Christian Militzer, Guido Schiffer
  • SUBSTITUTED PYRAZOLAMIDES AND THEIR USE
    Publication number: 20110172207
    Abstract: The present invention relates to novel substituted pyrazolamides, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: September 16, 2010
    Publication date: July 14, 2011
    Applicant: AiCuris Gmbh & Co. KG
    Inventors: Rudolf SCHOHE-LOOP, Reinhold Welker, Arnold Paessens, Marcus Bauser, Friederike Stoll, Frank Dittmer, Kerstin Henninger, Daniela Paulsen, Dieter Lang
  • Substituted quinolones III
    Patent number: 7977349
    Abstract: The invention relates to substituted quinolones and to methods for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: July 12, 2011
    Assignee: Aicuris GmbH & Co. KG
    Inventors: Chantal Fuerstner, Kai Thede, Holger Zimmermann, David Brueckner, Kerstin Henninger, Dieter Lang, Rudolf Schohe-Loop