Patents Assigned to AJINOMOTO CO. IN
  • Method of analyzing L-tryptophan in biological samples, and kit used therein
    Patent number: 9695460
    Abstract: Disclosed is a method for quantifying L-tryptophan involving a step for mixing a specimen, L-tryptophan oxidase, and water, a step for allowing the obtained reaction solution to stand a predetermined period of time in the presence of oxygen, and a step for measuring the reaction product resulting from action of enzymes present in the reaction solution after allowing to stand. Also disclosed are a kit used to quantify the L-tryptophan containing L-tryptophan oxidase, and an enzyme sensor using the L-tryptophan oxidase. This method, kit and enzyme sensor use an L-tryptophan-specific enzyme, so are capable of quantifying L-tryptophan even in the presence of other amino acids.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: July 4, 2017
    Assignees: Public University Corporation Toyama Prefectural University, Ajinomoto Co., Inc.
    Inventors: Yasuhisa Asano, Masafumi Kameya, Hiroyasu Onaka
  • MOISTURIZER AND COSMETIC CONTAINING SAME
    Publication number: 20170181947
    Abstract: The present invention provides a composition containing (A) and (B), which shows a decreased peculiar odor of acylproline and a salt thereof, has a moist feeling and is superior in the stability: (A) acylproline represented by the formula (1) or a salt thereof (wherein an acyl group represented by R1—CO— is an acyl group induced from saturated or unsaturated fatty acid having 3-23 carbon atoms) (B) a zinc salt of pyrrolidone carboxylate.
    Type: Application
    Filed: March 10, 2017
    Publication date: June 29, 2017
    Applicant: AJINOMOTO CO., INC.
    Inventors: Nana HARAYA, Eiko OSHIMURA
  • Resin composition for sealing
    Patent number: 9676978
    Abstract: A sealing resin composition simultaneously having good transparency, resistance to moisture permeability, and adhesiveness resistant to heat and humidity, and a sealing resin composition sheet obtained therefrom. Using a resin composition containing (A) a styrene-isobutylene modified resin and (B) a tackifier resin as a sealing resin composition, a resin composition layer composed of the resin composition may be formed on a support to give a sealing resin composition sheet.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: June 13, 2017
    Assignee: AJINOMOTO CO., LTD.
    Inventor: Yuichi Kageyama
  • Method for producing gamma-glutamylvalylglycine or a salt thereof
    Patent number: 9677106
    Abstract: A method for producing ?-Glu-Val-Gly comprising the step of reacting Val-Gly with a ?-glutamyl group donor in the presence of a ?-glutamyltransferase, a microorganism containing the enzyme, or a processed product thereof to generate ?-Glu-Val-Gly, wherein the ?-glutamyltransferase consists of a large subunit and a small subunit, and the small subunit has a specific mutation.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: June 13, 2017
    Assignee: Ajinomoto Co., Inc.
    Inventors: Hiroyuki Nozaki, Isao Abe, Jun Takakura, Rie Takeshita, Hideyuki Suzuki, Shunichi Suzuki
  • Diphenylmethane compound
    Patent number: 9670121
    Abstract: The present invention aims to provide a compound superior in broad utility and stability, which is useful as a protecting reagent (anchor) of amino acid and/or peptide in liquid phase synthesis and the like of a peptide having a C-terminal etc., which are of a carboxamide (—CONHR)-type, an organic synthesis reaction method (particularly peptide liquid phase synthesis method) using the compound, and a kit for peptide liquid phase synthesis containing the compound, and has found that the object can be achieved by a particular compound having a diphenylmethane skeleton.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: June 6, 2017
    Assignee: AJINOMOTO CO., INC.
    Inventor: Daisuke Takahashi
  • RESIN COMPOSITION
    Publication number: 20170154841
    Abstract: Resin compositions containing (A) an epoxy resin, (B) a curing agent, and (C) an inorganic filler in which the content of (C) the inorganic filler is 55% by mass or higher with respect to 100% by mass of a non-volatile component within the resin composition, the average particle diameter of (C) the inorganic filler is 0.05 to 0.35 ?m, the product of the specific surface area (m2/g) of (C) the inorganic filler and the true density of (C) the inorganic filler is 1 to 77 m2/g and the moisture permeation of a cured product obtained by thermally cured the resin composition is 0.05 to 2.8 g˜mm/m2·24 h are useful for making printed wiring boards.
    Type: Application
    Filed: November 29, 2016
    Publication date: June 1, 2017
    Applicant: Ajinomoto Co., Inc.
    Inventors: Shigeo NAKAMURA, Kazuhiko TSURUI, Shiro TATSUMI
  • Lung cancer evaluating apparatus, method, system, and program and recording medium therefor
    Patent number: 9664681
    Abstract: According to the method of evaluating lung cancer, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a lung cancer state in the subject is evaluated based on the concentration value of at least one of Orn, Lys, ABA, Arg, Glu, His, Tau, Pro, Ala, Cit and Ile contained in the measured amino acid concentration data of the subject.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: May 30, 2017
    Assignee: Ajinomoto Co., Inc.
    Inventors: Akira Imaizumi, Nobukazu Ono, Ryosei Sakai, Toshihiko Ando, Naoyuki Okamoto, Fumio Imamura, Masahiko Higashiyama
  • Method for analysis of compounds with amino group and analytical reagent therefor
    Patent number: 9658234
    Abstract: The present invention provides a method for the analysis of a compound with amino group (e.g., an amino acid or peptide) contained in a sample and convenient manner with a high sensitivity. The compound with amino group in a sample containing the compound with amino group is labeled with a specific carbamate compound such as p-trimethylammonium anilyl-N-hydroxysuccinimidyl carbamate iodide to enhance the selectivity and sensitivity. The present invention is preferably used in conjunction with mass spectrometry such as MS/MS method to facilitate quantitative analysis. The present invention further provides labeling reagents for mass spectrometry.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: May 23, 2017
    Assignee: AJINOMOTO CO., INC.
    Inventors: Hiroshi Miyano, Akihisa Yahashi, Kazutaka Shimbo, Masakazu Nakazawa, Kazuo Hirayama
  • MEDIUM-CHAIN ACYL BASIC AMINO ACID DERIVATIVE
    Publication number: 20170137372
    Abstract: The present invention aims to provide a medium-chain acyl basic amino acid derivative which, when blended in a liquid 5 cosmetic such as skin lotion, skin milk and the like, suppresses gelation while maintaining affinity to the skin and the like and can afford a stable preparation. The present invention relates to a compound represented by the formula (1) wherein each symbol is as described in the DESCRIPTION, or a salt thereof.
    Type: Application
    Filed: January 27, 2017
    Publication date: May 18, 2017
    Applicant: AJINOMOTO CO., INC.
    Inventors: Shun KOBAYASHI, Masayuki Kuramoto
  • COATED PARTICLES
    Publication number: 20170137563
    Abstract: An object of the present invention is to provide curing agent composite particles for epoxy resin, which are less likely to aggregate, and are excellent in storage stability and solvent resistance. Coated particles of the present invention comprise (A) curing agent particles for epoxy resin, and (B) an alkoxy oligomer, wherein the surfaces of the curing agents for epoxy resin particle are coated with the alkoxy oligomer.
    Type: Application
    Filed: November 11, 2016
    Publication date: May 18, 2017
    Applicant: AJINOMOTO CO., INC.
    Inventors: Takayuki TANAKA, Eriko SATOU, Yuji KOSHIMA, Junji OHASHI
  • L-amino acid-producing bacterium and a method for producing an L-amino acid
    Patent number: 9644009
    Abstract: An L-amino acid is produced by culturing a microorganism of the family Enterobacteriaceae which has the ability to produce an L-amino acid and which has been modified so as to increase the expression of the evgA gene, the gadE gene, and/or the ydeO gene. These genes encode a transcription factor involved in the EvgAS two-component system regulon. The culture takes place in a medium, and the L-amino acid is collected from the medium or cells.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: May 9, 2017
    Assignee: AJINOMOTO CO., INC.
    Inventors: Shintaro Iwatani, Akira Imaizumi, Yoshihiro Usuda, Kazuhiko Matsui
  • Method for Producing L-Amino Acid of Glutamate Family
    Publication number: 20170121743
    Abstract: A method for producing an L-amino acid of glutamate family such as L-glutamic acid is provided. An L-amino acid of glutamate family is produced by culturing a coryneform bacterium having an ability for producing an L-amino acid of glutamate family, which has been modified so that the activity of an ?-ketoglutaric acid (?-KG) uptake carrier is increased, in a medium, and collecting the L-amino acid of glutamate family from the medium.
    Type: Application
    Filed: October 26, 2016
    Publication date: May 4, 2017
    Applicant: AJINOMOTO CO., INC.
    Inventors: Seiko Hirano, Kazuyuki Hayashi, Hitoshi Takayashiki, Keita Fukui
  • Standard solution for use in analysis of amino acid in plasma
    Patent number: 9638706
    Abstract: An external standard solution for use in the analysis of amino acid in plasma, containing, (1) at least one amino acid selected from the following components A, at a concentration of 0.0007 M to 0.49 M, and (2) (i) at least one amino acid selected from the following components B, at a concentration of 0.2 to 0.9 times of the lowest-concentration amino acid among the amino acids selected from components A, (ii) at least one amino acid selected from the following components C, at a concentration of 0.1 to 0.4 times of the lowest-concentration amino acid among amino acids selected from the components A, or (iii) at least one amino acid selected from the following components D, at a concentration of 0.05 to 0.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: May 2, 2017
    Assignees: WAKO PURE CHEMICAL INDUSTRIES, LTD., AJINOMOTO CO., INC.
    Inventors: Masako Hayakawa, Kazutaka Shimbo, Hiroo Yoshida
  • COSMETIC COMPOSITION
    Publication number: 20170112751
    Abstract: A method for perming or coloring hair, in which hair is treated with a cosmetic composition including a protein-glutaminase and not including an alkaline substance. A method of enhancing hair-permeation of an active ingredient included in a cosmetic composition, in which a protein glutaminase is included in the cosmetic composition. The cosmetic composition does not include an alkaline substance, and the active ingredient is at least one of a hair perm agent and a hair coloring agent.
    Type: Application
    Filed: January 5, 2017
    Publication date: April 27, 2017
    Applicant: AJINOMOTO CO., INC.
    Inventors: Keiichi YOKOYAMA, Eiko OSHIMURA, Masayo DATE, Yukiko UMEZAWA
  • Nutrition composition
    Patent number: 9629386
    Abstract: The present invention can provide a nutrition composition useful for patients with renal diseases, which has an effective prophylactic or improving effect for various symptoms of malnutrition, inflammation, arteriosclerosis, abnormal lipid metabolism and oxidative stress, associated with renal diseases, or for diabetic nephropathy. The nutrition composition of the present invention m contains one or more kinds of free amino acids selected from the group consisting of valine, leucine, isoleucine and histidine, and a lipid comprising ?-3 fatty acid and ?-6 fatty acid at a weight ratio (?-6 fatty acid to ?-3 fatty acid) of 0.5-5.5. In addition, the composition further contains a soybean protein or a hydrolysate thereof together with the aforementioned lipid or instead of the aforementioned lipid.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: April 25, 2017
    Assignee: AJINOMOTO CO., INC.
    Inventors: Shinji Somekawa, Tomoyuki Mine, Naoki Hayashi
  • SWEETNESS RECEPTOR ANTAGONIST
    Publication number: 20170101372
    Abstract: Sweetness receptor antagonists represented by formula (I): wherein each symbol is described herein, are useful for the prophylaxis or treatment of metabolic syndrome, diabetes, obesity and the like.
    Type: Application
    Filed: December 23, 2016
    Publication date: April 13, 2017
    Applicant: AJINOMOTO CO., INC.
    Inventors: Yoshiro KITAHARA, Koji OHSUMI, Seiji KITAJIMA, Shimpei OGAWA
  • Method for producing 1,5-pentanediamine
    Patent number: 9617202
    Abstract: A simple and efficient method for producing 1,5-pentanediamine in a free form is provided. The method for producing 1,5-pentanediamine in a free form from a salt of 1,5-pentanediamine includes a step of adsorbing 1,5-pentanediamine in a free form onto a column of an ion exchange resin by applying a solution of salt of 1,5-pentanediamine to the column of the ion exchange resin, and a step of eluting a solution of the 1,5-pentanediamine in a free form from the ion exchange resin by applying an eluent solution to the column of the ion exchange resin onto which the 1,5-pentanediamine in a free form is absorbed.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: April 11, 2017
    Assignee: AJINOMOTO CO., INC.
    Inventors: Takehiro Hiura, Akifumi Hasegawa, Takehiko Chikamori
  • Method for producing protein by precipitation
    Patent number: 9617299
    Abstract: A method of purifying a fusion protein, including: (1) adjusting the pH of an aqueous phase, containing a fusion protein which is a fusion of a protein having a self-assembly capability and a tamet protein, and which aqueous phase has a first pH, to a second pH, to obtain a remaining aqueous phase and a solid fraction containing an amount of the fusion protein; (2) separating the solid fraction from the remaining aqueous phase, to obtain a separated solid fraction; and (3) dissolving the separated solid fraction in a solution having a pH of 12 or lower but higher than the second pH by at least 0.1 pH units, wherein the protein having a self-assembly capability is a cell surface protein.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: April 11, 2017
    Assignee: AJINOMOTO CO., INC.
    Inventors: Takahiro Nonaka, Teruhisa Mannen, Noriko Tsurui
  • COSMETIC COMPOSITION CONTAINING 3-O-ALKYL-L-ASCORBIC ACID OR SALT THEREOF
    Publication number: 20170087078
    Abstract: The present invention provides a cosmetic composition containing (A) 3-O-alkyl-L-ascorbic acid wherein the alkyl group has 8-12 carbon atoms or a salt thereof, (B) one or more kinds of nonionic surfactants selected from the group consisting of polyoxyethylene polyoxypropylene alkyl ether, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene alkyl ether and polyoxyethylene alkenyl ether, and having an HLB value of 12.5-17, and (C) one or more kinds of oil agents selected from the group consisting of amino acid ester, dimer acid ester, hydroxy acid ester, alkyl glyceryl ether and alkenyl glyceryl ether, which is superior in solubilization stability, preservation stability and sense of use, and free of time-dependent development of an odor which poses a problem when in use.
    Type: Application
    Filed: December 9, 2016
    Publication date: March 30, 2017
    Applicant: AJINOMOTO CO., INC.
    Inventor: Mandai YAMADA
  • Process for producing material for food or beverage
    Patent number: 9603375
    Abstract: Heating an oil from a plant or animal while supplying oxygen at a dissolved oxygen supply speed of not less than 0.058 mg/L/min to the oil from plant or animal is a convenient production method of a material for food or drink, which is capable of imparting an aroma and/or a flavor, which are/is mellow and rich in variety, to a food or drink.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: March 28, 2017
    Assignee: AJINOMOTO CO., INC.
    Inventors: Hideki Yamamoto, Yukiko Takakura, Makoto Yamada