Patents Assigned to AJINOMOTO CO. IN
  • MANUFACTURING METHOD FOR IMPROVED PROTEIN-CONTAINING FOOD AND FORMULATION FOR IMPROVING PROTEIN-CONTAINING FOOD
    Publication number: 20160309746
    Abstract: A method for producing a modified food containing a protein and a preparation for modifying a food containing a protein are provided. A food raw material containing a protein is treated by using an oxidizing agent and/or an oxidoreductase in combination with a metal and/or a metal-containing substance to produce a food containing a protein.
    Type: Application
    Filed: July 5, 2016
    Publication date: October 27, 2016
    Applicant: AJINOMOTO CO., INC.
    Inventors: Hiroaki SATO, Hiroyuki NAKAGOSHI, Masao KOTANI, Yoshie KOBAYASHI
  • Method for Producing L-Isoleucine Using a Bacterium of the Family Enterobacteriaceae Having Overexpressed the cycA Gene
    Publication number: 20160312254
    Abstract: The present invention provides a method for producing L-isoleucine by fermentation using a bacterium belonging to the family Enterobacteriaceae which has been modified to overexpress the cycA gene. The method also allows reducing the amount of byproduct amino acids that are produced during fementative production of L-isoleucine using Enterobacteriaceae bacterium having an L-isoleucine-producing ability.
    Type: Application
    Filed: April 13, 2016
    Publication date: October 27, 2016
    Applicant: AJINOMOTO CO., INC.
    Inventors: Christina Dmitrievna Hook, Valery Vasilievich Samsonov, Natalia Sergeevna Eremina, Natalia Viktorovna Stoynova, Tatiyana Sergeevna Sidorova
  • Method for producing L-amino acid using microorganism having increased phosphate transporter activity
    Patent number: 9476076
    Abstract: A method for producing an L-amino acid is provided. An L-amino acid is produced by culturing a coryneform bacterium having an L-amino acid-producing ability, which is modified so that the activity of a phosphate transporter is increased, in a medium, and collecting the L-amino acid from the medium.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: October 25, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Seiko Hirano, Kazuyuki Hayashi
  • FOOD CONTAINING HISTIDINE AND USE THEREOF
    Publication number: 20160295904
    Abstract: Ingesting a food etc. which is in a unit package form per meal and contains, in the unit, not less than 0.3 g of histidine as an ingestion amount per meal is effective for improving mental energy and biorhythm.
    Type: Application
    Filed: April 7, 2016
    Publication date: October 13, 2016
    Applicant: AJINOMOTO CO., INC.
    Inventors: Tetsuro SHIBAKUSA, Mayu SUGITA, Ikuko SASAHARA, Naoto KOYAMA, Shinobu SEKI
  • Method for inactivating viruses with slightly acidic arginine
    Patent number: 9462810
    Abstract: The present invention provides a method for conveniently producing a protein formulation in which viruses are inactivated, without impairing the quality of the obtained protein formulation, characterized by including the step of exposing the protein formulation contaminated with the viruses to a 0.1-2M aqueous solution of arginine, an arginine derivative, or a mixture thereof, the aqueous solution being adjusted to pH 3.5 to 5. The present invention also provides a virus inactivation method characterized by including the step of contacting a virus-containing object with a 0.1-2M aqueous solution of arginine, an arginine derivative, or a mixture thereof, the aqueous solution being adjusted to pH 3.5 to 5.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: October 11, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Hajime Koyama, Tsutomu Arakawa, Daisuke Ejima
  • Acyl dipeptide derivative
    Patent number: 9464110
    Abstract: An acyl dipeptide derivative represented by the formula (1): wherein an acyl group represented by R1—CO— is a saturated or unsaturated, straight or branched chain acyl group having 2-24 carbon atoms, R2 and R3 are each independently a hydrogen atom, an OH group or an OR5 group, R5 is a saturated or unsaturated, straight or branched chain hydrocarbon group having 1-6 carbon atoms, and R4 is a hydrogen atom, or a saturated or unsaturated, straight or branched chain hydrocarbon group having 1-6 carbon atoms, or a salt thereof has a superior antimicrobial effect, and a composition containing the compound is superior in the sensory feel.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: October 11, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventor: Takanori Sugimoto
  • Poly ?-amino acid and ferroelectric memory element using same
    Patent number: 9464167
    Abstract: Ferroelectric memory elements which contain a poly ?-amino acid which is a copolymer containing a glutamic acid-?-ester unit represented by the formula (I), defined herein, and a glutamic acid-?-ester unit represented by the formula (II), defined herein, in a molar ratio of units of formula (I) to units of formula (II) of 10/90-90/10 are useful as recording elements such as RFID and the like.
    Type: Grant
    Filed: November 11, 2013
    Date of Patent: October 11, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Satoru Ohashi, Sei Uemura, Manabu Kitazawa, Toshihide Kamata
  • Method of evaluating prostatic disease
    Patent number: 9465031
    Abstract: According to the method of evaluating prostatic disease of the present invention, amino acid concentration data on concentration values of amino acids in blood collected from a subject to be evaluated is measured, and the state of prostatic disease including at least one of prostatic cancer and prostatic hypertrophy in the subject is evaluated based on the concentration value of at least one of Tau, Thr, Ser, Asn, Glu, Pro, Gly, Ala, Cit, ABA, Val, Met, Ile, Leu, Phe, His, Trp, Orn, Lys, and Cys2 contained in the measured amino acid concentration data of the subject.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: October 11, 2016
    Assignee: Ajinomoto Co., Inc.
    Inventors: Naoyuki Okamoto, Takeshi Miura, Yohei Miyagi, Akira Imaizumi, Hiroshi Yamamoto, Takayuki Tanaka, Takahiko Muramatsu, Toshihiko Ando, Noriko Takahashi
  • Novel Gene and Method for Producing L-Amino Acids
    Publication number: 20160289716
    Abstract: The present invention describes a bacterium which has an ability to produce an amino acid and in which the rhtC gene encoding a protein having an enhanced activity of imparting L-threonine resistance to a bacterium expressing the protein. Preferably, the bacterium further includes an rhtB gene encoding for a protein having an enhanced activity of imparting to a bacterium L-homoserine resistance expressing the protein. The present invention also describes a method of cultivating the bacterium in a culture medium to produce and accumulate amino acids in the medium, and the amino acid is recovered from the medium.
    Type: Application
    Filed: June 17, 2016
    Publication date: October 6, 2016
    Applicant: AJINOMOTO CO., INC.
    Inventors: Vitaliy Arkadyevich Livshits, Natalia Pavlovna Zakataeva, Vladimir Veniaminovich Aleshin, Alla Valentinovna Belareva, Irina Lyvovna Tokhmakova
  • ANTI-FATIGUE COMPOSITION
    Publication number: 20160287616
    Abstract: Compositions and foods which contain (1) histidine and (2) vitamin B6 and/or carnosine are useful for treating, improving, and recovering from fatigue.
    Type: Application
    Filed: April 7, 2016
    Publication date: October 6, 2016
    Applicant: AJINOMOTO CO., INC.
    Inventors: Tetsuro SHIBAKUSA, Mayu SUGITA
  • 1,5-PENTAMETHYLENE DIAMINE AND PRODUCTION METHOD THEREFOR
    Publication number: 20160289165
    Abstract: A biomass resource-derived 1,5-pentamethylene diamine produces a polyamide resin composition having a good color tone. The 1,5-pentamethylene diamine in which a total of the contents of an acetamide, 2,3,4,5-tetrahydropyridine, 2-piperidone, ?-amino-?-caprolactam, lysine and ornithine that the 1,5-pentamethylene diamine contains as impurities is less than or equal to 150 weight ppm.
    Type: Application
    Filed: November 18, 2014
    Publication date: October 6, 2016
    Applicants: Toray Industries, Inc., Ajinomoto Co., Inc.
    Inventors: Yoshiaki Murata, Takahiro Kuribayashi, Fumito Onishi, Takehiro Hiura
  • L-amino acid-producing bacterium and a method for producing an L-amino acid
    Patent number: 9458206
    Abstract: A bacterium belonging to the family Enterobacteriaceae, which has an ability to produce an amino acid such as L-cysteine and has been modified to have specific mutation in the yeas gene, is cultured in a medium, and the L-amino acid is collected from the medium.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: October 4, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Kazuhiro Takumi, Gen Nonaka
  • Moisturizer and cosmetic agent containing same
    Patent number: 9456971
    Abstract: Provided is a moisturizer having hygroscopicity and water retention ability, and also provided is a composition superior in antiseptic property and feeling on application, in addition to moisturizing property, and free of coloration and odorization. A moisturizer containing acylproline represented by the formula (1) wherein an acyl group represented by R1—CO— is an acyl group derived from a saturated or unsaturated fatty acid having 3-23 carbon atoms, or a salt thereof, and a composition containing (A) acylproline represented by the above formula (1) or a salt thereof and (B) bisphosphonate.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: October 4, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Takanori Sugimoto, Nana Haraya, Masatoshi Saito
  • Polyester compound
    Patent number: 9458288
    Abstract: Polyester compounds obtained by reaction of a compound represented by formula (1): (defined herein) with a compound represented by formula (2): (defined herein) exhibit high thermal resistance.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: October 4, 2016
    Assignee: Ajinomoto Co., Inc.
    Inventors: Fumi Shozui, Ryotaro Nakaya, Takashi Ineyama, Keiichi Yokoyama
  • Polyester compound
    Patent number: 9458289
    Abstract: Polyester compounds obtained by reaction of a compound represented by formula (1): (defined herein) with a compound represented by formula (2): (defined herein) exhibit high thermal resistance.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: October 4, 2016
    Assignee: Ajinomoto Co., Inc.
    Inventors: Fumi Shozui, Ryotaro Nakaya, Takashi Ineyama, Keiichi Yokoyama
  • Method of evaluating breast cancer, breast cancer-evaluating apparatus, breast cancer-evaluating method, breast cancer-evaluating system, breast cancer-evaluating program and recording medium
    Patent number: 9459255
    Abstract: According to the method of evaluating breast cancer of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a breast cancer state in the subject is evaluated based on the concentration value of at least one of Ser, Gln, Val, Cys, Orn, Arg, Ile and ABA contained in the measured amino acid concentration data of the subject.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: October 4, 2016
    Assignee: Ajinomoto Co., Inc.
    Inventors: Akira Imaizumi, Toshihiko Ando, Naoyuki Okamoto
  • Modified leucine dehydrogenase
    Patent number: 9453206
    Abstract: The present invention provides a means and method useful for measurement of a total branched-chain amino acid concentration. Specifically, the present invention provides a modified enzyme in which at least one amino acid residue is mutated so as to improve a property of a leucine dehydrogenase which is associated with the measurement of the total branched-chain amino acids, such as, for example, substrate specificities of leucine dehydrogenase for total branched-chain amino acids, activity of leucine dehydrogenase for any branched-chain amino acids, and thermal stability of leucine dehydrogenase; and a method of analyzing the total branched-chain amino acids, comprising measuring the total branched-chain amino acids contained in a test sample using the modified enzyme.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: September 27, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Wataru Hoshino, Yuya Kodama, Toshimi Mizukoshi, Uno Tagami
  • Method for producing 3-acetylamino-4-hydroxybenzoic acid
    Patent number: 9447443
    Abstract: The present invention provides a method for conveniently and efficiently producing a 3-acetylamino-4-hydroxybenzoic acid-type compound that is a stable compound by a process using a microorganism. Specifically the present invention provides a microorganism having an ability to produce 3-amino-4-hydroxybenzoic acid, that is modified so as to increase an activity to form 3-amino-4-hydroxybenzoic acid from dihydroxyacetone phosphate and aspartate semialdehyde, wherein the microorganism is modified so as to increase an N-hydroxyarylamine O-acetyltransferase (NhoA) activity, as well as a method for producing the 3-acetylamino-4-hydroxybenzoic acid-type compound using such a microorganism.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: September 20, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Fumi Shozui, Yoshinori Tajima, Keiichi Yokoyama
  • Piezoelectric element
    Patent number: 9450174
    Abstract: Poly(?-amino acid) which contain: (A) a glutamic acid ?-ester unit represented by formula (I): and (B) one or more kinds of units selected from a glutamic acid ?-ester unit represented by formula (II), an alanine unit, a phenylalanine unit and an N?-benzyloxycarbonyllysine unit, represented by formula (III), and a glutamic acid ?-ester unit represented by formula (IV) can be dissolved in various solvents and are useful for preparing piezoelectric elements which exhibit superior piezoelectricity.
    Type: Grant
    Filed: August 13, 2014
    Date of Patent: September 20, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Satoru Ohashi, Sei Uemura, Manabu Kitazawa, Toshihide Kamata, Yoshinori Wada
  • METHOD FOR PRODUCING PEPTIDE HYDRAZIDE, PEPTIDE AMIDE, AND PEPTIDE THIOESTER
    Publication number: 20160264626
    Abstract: An object of the present invention is to provide a method for producing a peptide thioester compound, a peptide hydrazide compound, and a peptide amide compound. The present invention provides a method for producing a peptide hydrazide compound or a peptide amide compound by using a compound represented by Formula (2): wherein R1, R2, R3, and X are as defined in the specification, and using a hydrazine compound or an ammonia compound as a reaction reagent. The present invention also provides a method for producing a peptide thioester compound from the peptide hydrazide compound.
    Type: Application
    Filed: May 4, 2016
    Publication date: September 15, 2016
    Applicant: AJINOMOTO CO., INC.
    Inventors: Akira OTAKA, Akira Shigenaga, Masakazu Sugiyama, Hidemi Fujii