Abstract: The present invention provides a highly controlled complex comprising an antibody and ferritin particles. More specifically, the present invention provides the inventions of a complex or salt thereof comprising (A) one IgG antibody and (B) two human ferritin particles comprising one or more human ferritin H chains linked thereto; and methods for producing the same.

Abstract: A bacteriophage which consists of the nucleotide sequence represented by SEQ ID NO: 1 or a nucleotide sequence having 90% or more identity thereto, as its genome, is capable of infecting and lysing a diabetes-inducible bacterium belonging to Fusimonas intestini,containing a cyclic single-stranded DNA.

Abstract: A resin sheet including a support and a resin composition layer formed on the support, in which the resin composition layer contains (A) an epoxy resin, (B) an organic solvent, (C) an inorganic filler, and (D) a stress relaxing material, in which a content of an aromatic solvent having a boiling point of lower than 120° C. in the (B) component is in the range of 0 to 9% by mass relative to 100% by mass of total of the (B) component, can suppress an irregularity after lamination and a warpage after curing.

Abstract: Resin compositions including (A) a hollow organic polymer particle, (B) an epoxy resin, and (C) a curing agent provide cured products having a superior smear removal properties.

Abstract: A method for producing RNA is provided. Objective RNA is produced by culturing a coryneform bacterium having an expression unit for the objective RNA, which has been modified so that the activity of ribonuclease III is reduced, in a medium, to express the objective RNA and accumulate the objective RNA in cells of the bacterium, and collecting the objective RNA from the cells.

Abstract: A frozen shumai in which hardening of a part of a shumai wrapper which is not in contact with a shumai filling is suppressed, and deterioration of texture during eating is improved even when the frozen shumai taken out from a freezer is heated as it is in a microwave oven without a treatment or operation of spraying water on the surface of the frozen shumai or covering the frozen shumai with a food wrap film is provided. Specifically, a frozen shumai containing a shumai wrapper and a shumai filling, wherein a water content of a part of the shumai wrapper which is not in contact with the shumai filling is 35 wt % to 80 wt % after heating the shumai as it is in a microwave oven until a core temperature of the shumai reaches 50° C. to 90° C. is provided.

Abstract: Provided is a quick and simple method for screening dimerized cyclic peptides, a library therefor, and molecules including cyclic peptides that can be used in the method and the library. For example, the method for screening dimerized cyclic peptides includes (1) a step in which, in a cell-free expression system, a cyclic peptide, a dimerization domain including a cysteine residue and a leucine zipper region, and at least one polypeptide including a peptide linker existing between the cyclic peptide and the dimerization domain are synthesized, and a dimer of the polypeptide is prepared, and (2) a step in which activity based on binding between the dimer and a target molecule is measured.

Abstract: Livestock meat flavor-imparting agents containing a heated product of crude sugar, and cysteine or a salt thereof are useful for imparting livestock meat flavors without containing livestock meat materials.

Abstract: Oxidizing an oligonucleotide precursor having a phosphite ester bond or a phosphonate ester bond with an oxidant, wherein the oxidant is a compound represented by the formula (I) excluding 2,2-dipyridyl disulfide: wherein the symbols are as defined in the specification is useful for producing an oligonucleotide having a phosphate ester bond.

Abstract: the present invention provides a method for producing a protein having a supramolecular structure in which a bioactive substance is encapsulated, comprising: (I) bringing a subunit of a protein, which forms a supramolecular structure, a bioactive substance, and a solution for forming the protein having the supramolecular structure from the subunit into contact with one another in a flow micro mixer.

Abstract: A feeding management system for a free stall cow barn includes an evaluation-related information storage unit, an association information storage unit, an evaluating unit, a selecting unit, a transmission unit, a reading unit, a feed information acquiring unit, a device information acquiring unit, and a control information transmitting unit.

Abstract: A desired antibody or antibody composition may be obtained by modifying a thiol group chemically introduced to an antibody to obtain an antibody composition comprising (A) an antibody intermediate or a salt thereof having a bioorthogonal functional group which may be protected, which is represented by the following formula (A): AbS-L-R]n??(A) wherein Ab is a certain antibody, S is a sulfur atom, L is a divalent group, R is a bioorthogonal functional group which may be protected, and n is an integer from 1 to 8, and (B) a thiol group-introduced antibody or a salt thereof, which is represented by the following formula (B): AbSH]n??(B) wherein Ab and n are the same as formulae (A), and SH is a thiol group; and the like.

Abstract: Compounds and salts thereof represented by the following formula (I): wherein X indicates a leaving group, Y indicates an affinity peptide having a binding region to a CH2 domain in an immunoglobulin unit containing two heavy chains and two light chains, O indicates an oxygen atom, S indicates a sulfur atom, W indicates an oxygen atom or a sulfur atom, La indicates a first linker, Lb indicates a second linker, and the total number of atoms constituting a main chain in the first linker and atoms constituting a main chain in the second linker are 5 to 7, facilitate regioselective modification of an antibody with a functional substance and control of the bonding ratio of the antibody to the functional substance within a desired range.

Abstract: To provide a set for microwave heating that is capable of giving a crispy texture to a food by using a heating element configured to generate heat by microwave irradiation and is capable of maintaining softness of a portion in a surface of a food other than a fried face if any, and to provide a package including the set for microwave heating and an outer packaging bag configured to accommodate the set for microwave heating. Provided is a set for microwave heating, comprising: a tray; a food accommodated in the tray; and a heating laminate comprising a heating element configured to generate heat by microwave irradiation, and a substrate, wherein the heating laminate is disposed in such a way that the heating element side faces the food, and the substrate is laminated on a face of the heating element, the face being opposite to another face of the heating element, the another face being to be or come in contact with the food.

Abstract: The present invention provides a coated-type feed additive composition for improving body weight gain of livestock or feed conversion ratio for livestock comprising: a core containing a physiologically active substance having a property of strengthening a membrane of intestinal epithelial cells; and a core coating agent.

Abstract: Culture media, which contain albumin carrying a reduced amount of fatty acid, are useful for culturing stem cells.

Abstract: A mixing apparatus is configured to efficiently input noodles coated with an additive to a receiving tray, with no need to perform weighing again after the noodles are input to the receiving tray. The mixing apparatus includes at least two hoppers that each house falling noodles and that allows the noodles to fall through rotation of the hoppers. A supply device supplies a sauce to the noodles in the hoppers, and the two hoppers are spaced from one another in the falling direction.

Abstract: Provided is a method of producing an L-amino acid such as L-glutamic acid and the like. An L-amino-acid is produced by cultivating a coryneform bacterium having L-amino acid-producing ability in a culture medium, which has been modified so as to have one or more of the following modifications: (A) a modification for increasing activity of acetate kinase, (B) a modification for increasing activity of fructose-1,6-bisphosphatase, (C) a modification for decreasing activity of pyruvate dehydrogenase, (D) a modification for decreasing activity of aspartate transaminase, and (E) a modification for decreasing activity of malic enzyme; and collecting the L-amino acid from the culture medium and/or the bacterial cells.

Abstract: The present invention provides a 2-OST mutant exhibiting a high activity.

Abstract: A microorganism useful as an expression host for ?-Glu-Val synthetase and a method for producing ?-Glu-Val-Gly using ?-Glu-Val synthetase expressed in the microorganism are provided. By using ?-Glu-Val synthetase expressed in a bacterium, such as Escherichia bacteria, modified so that the activity of a protein encoded by a ybdK gene (YBDK) is reduced as an expression host, ?-Glu-Val-Gly is produced from Glu, Val, and Gly as raw materials.