Abstract: Certain embodiments provide a cover mounted on top of a manifold, the cover comprising an exhaust opening and an inner surface forming a space between the inner surface of the cover and an outer surface of the manifold, wherein the space is configured to receive pressurized gas at an inlet positioned on a first side of a valve. The valve is coupled to the outer surface of the manifold and positioned within the space. The exhaust opening is positioned on a second side of the valve opposite the first side of the valve such that pressurized gas circulates from the inlet around the valve and exits through the exhaust opening.

Abstract: An injection molding apparatus for manufacturing an ophthalmic lens mold having a front surface comprising a lens forming portion and a rear surface, comprises a first molding tool and a second molding tool. The first and second molding tools are movable towards and away from each other between a closed position and an open position. In the closed position the first mold forming portion of the first molding tool and the second mold forming portion of the second molding tool define a cavity between them corresponding in shape to the shape of the ophthalmic lens mold. The surface of the second mold forming portion, at least in a central zone thereof, has a surface roughness Sa in the range of 0.3 ?m to 2 ?m, and a surface roughness Sz in the range of 10 ?m to 50 ?m.

Abstract: Intraocular lens loading devices and methods of use. In some embodiment the devices are used to sequentially splay first and second haptics while loading the intraocular lens into a delivery lumen.

Abstract: Techniques for controlling data access using machine learning are provided. In one aspect, first, second, and third training data sets are generated from a set of historical access records and a set of historical data records, where the access records correspond to requests for data and comprise information identifying whether the request satisfies one or more data access rules, and the data records correspond to data elements and comprise information identifying whether the data element satisfies the one or more data access rules. One or more machine learning models are trained based on the first, second, and third training data sets to generate an output identifying whether requests for data should be granted.

Abstract: A system, method, and apparatus for performing intraocular lens implantation using real-time surgical reference indicium are disclosed. An example method includes recording a patient specific pre-operative still image of an eye prior to cyclorotation of the eye when a patient lies down for surgery and generating at least one real-time multidimensional visualization of at least a portion of the eye for display. The method further includes using the patient specific pre-operative still image to at least produce at least one virtual surgical reference indicium including an ocular natural vertical axis of the eye and align the at least one virtual surgical reference indicium to the eye in conjunction with the real-time multidimensional visualization of at least a portion of the eye. The patient specific pre-operative still image is captured under a dilation condition selected from the group consisting of natural dilation, chemical dilation, and no dilation.

Abstract: Systems and methods for initializing and calibrating an eye tracking system include an eye tracker configured to capture a first image of an eye from a first location and a second image of the eye from a second location, and a control processor configured to detect a first plurality of eye characteristics from the first image, the eye characteristics having first corresponding image coordinates, detect a second plurality of eye characteristics from the second image, the eye characteristics having second corresponding image coordinates, and determine a calibration offset and a calibration gain. The control processor may be further configured to determine an eye fixation position and orientation relative to an optical axis of the eye tracker based at least in part on the first corresponding image coordinates and/or the second corresponding image coordinates.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. In an exemplary aspect, the present disclosure is directed to a haptic optic management system. The haptic optic management system may include a housing. The haptic optic management system may further include a plate, wherein the plate is disposed within the housing. The haptic optic management system may further include a clip that engages the plate in the housing, wherein the clip comprises a clip body and a plurality of legs that extend from the clip body.

Abstract: An intraocular lens (IOL) configured to support a first optic for functioning as a single lens IOL and configured to support a second optic for functioning as a dual optic IOL. The base includes a first optic for providing a base power. A recess in an anterior rim of the base is configured for positioning a radial extension of a second optic. The geometry of the recess is configured to securely couple to the radial extension to prevent rotation of the second optic relative to the base and prevent tilting of the second optic relative to an optic axis.

Abstract: Systems and methods are presented for providing a vision simulation of a patient who has an eye condition. A composite image representing a real-world scene is obtained. The composite image includes multiple image layers, where each image layer represents objects that are at a particular viewing distance in the real-world scene. A first eye model representing the eye optics of the patient is generated. A second eye model representing the eye optics of a viewer is generated. The second eye model is modified by performing a mathematical function. A simulated image representing the vision of the patient is generated by convolving the first eye model and the modified second eye model with the composite image. In some embodiments, a tone mapping algorithm may also be applied to the simulated image to simulate a nighttime scene.

Abstract: A method for enhancing digital images during a microsurgery, e.g., an eye surgery, includes collecting digital images of target anatomy using a digital camera as the target anatomy is illuminated by warm white light. The method includes identifying, via a processor in communication with the digital camera, a predetermined stage of the microsurgery. Within the images, the processor digitally isolates a first pixel region, e.g., a pupil pixel region, from a second pixel region, e.g., an iris pixel region, and adjusts a characteristic of constituent pixels thereof. The method, possibly recorded as instructions in a computer-readable medium, may be used to enhance a red reflex at predetermined stages of an eye surgery. A system includes a lighting source for emitting warm white light having a color temperature of less than about 4000° K, the camera, and the processor.

Abstract: Methods and devices are adapted for implanting into the eye. An incision is formed in the cornea of the eye and a shunt is inserted through the incision into the anterior chamber of the eye. The shunt includes a fluid passageway. The shunt is passed along a pathway from the anterior chamber through the scleral spur of the eye into the suprachoroidal space and positioned in a first position such that a first portion of the fluid passageway communicates with the anterior chamber and a second portion of the fluid passageway communicates with the suprachoroidal space to provide a fluid passageway between the suprachoroidal space and the anterior chamber.

Abstract: Polymeric eye inserts are provided that may be dissolvable when placed in the cul-de-sac of the eye. These inserts may contain one or more mucoadhesive polymers, a biodegradable polymer as well as softener/plasticizer so that, when inserted into the eye, they may absorb tears, and dissolve and slowly release lubricant into the tear film to lubricate and protect the ocular surface for an extended duration of time. The biodegradable polymer containing eye insert may increase dissolution time on the ocular surface for longer lasting relief, may reduce dosing frequency and patient burden typically associated with topical drop usage. These polymeric eye inserts also may include one or more pharmaceutically active agents.

Abstract: In certain embodiments, a system for tracking movement of an eye comprises a camera system, a computer system, and an output device. The camera system generates images of the eye. The computer system stores the images and at least one of the images as a reference image. The computer system also tracks movement of the eye within a tracking range by comparing a current image with the reference image, and by determining a movement of the eye from the comparison of the current image and the reference image. The tracking range has one or more alert points. The computer system also determines an orientation of the eye relative to at least one alert point of the tracking range. The output device outputs a range indicator that indicates the orientation of the eye relative to the at least one alert point of the tracking range.

Abstract: Intraocular lens delivery devices and methods of use.

Abstract: Systems and methods for creating multi-spot laser light beams, multiplexing an illumination light and the multi-spot laser light beams, and delivering the multiplexed light to a surgical handpiece via a multi-core optical fiber cable.

Abstract: Systems and methods for creating multi-spot laser light beams, multiplexing an illumination light and the multi-spot laser light beams, delivering the multiplexed light to a surgical handpiece via a multi-core optical fiber cable, and delivering the multiplexed light onto patient anatomy.

Abstract: A gas mixture apparatus includes a measurement control system, an activation system, a pressurized chamber with one or more gases, and a mixing chamber. A filter can be preattached to an outlet of the mixture apparatus, allowing excess gas to be discharged therethrough and then atmospheric air to be drawn into the mixture apparatus through the filter for creating a therapeutic gas mixture.

Abstract: Systems and methods for intraocular lens selection include receiving, by one or more computing devices implementing a prediction engine, pre-operative multi-dimensional images of an eye; extracting, by the prediction engine, pre-operative measurements of the eye based on the pre-operative images; estimating, by the prediction engine using a prediction model based on a machine learning strategy, a post-operative position of an intraocular lens based on the extracted pre-operative measurements; selecting a power of the intraocular lens based on the estimated post-operative position of the intraocular lens; and selecting the intraocular lens based on the selected power. In some embodiments, the systems and methods further include receiving post-operative multi-dimensional images of the eye after implantation of the selected intraocular lens, extracting post-operative measurements of the eye, and updating the prediction model based on the pre-operative measurements and the post-operative measurements.

Abstract: A method of removing a lens forming material deposited on a lens forming surface (1) of a reusable glass mold for forming ophthalmic lenses, in particular contact lenses or intraocular lenses, comprises the steps of providing a plasma (2), exposing the lens forming surface (1) of the reusable glass mold to the plasma (2) for removing the lens forming material deposited on the lens forming surface (1). The plasma (2) is generated under atmospheric pressure and potential-free, or is generated under reduced pressure.

Abstract: Delivery devices for delivering an ophthalmic device into an eye. In some embodiments the delivery devices are adapted to deliver an intraocular lens into an eye.