Abstract: The invention relates to a novel carrier protein for use as a vaccine comprising the outer membrane protein C (OmpC) of Salmonella typhi Ty2 for conjugation with VI polysaccharide.

Abstract: The present invention provides an oligonucleotide primer pair having SEQ ID NO: 3 and SEQ ID NO: 4 for amplification of Early Secretory Antigenic Target (esat)-6-gene of Mycobacterium species. The invention also provides a method for detecting M .tuberculosis in a sample based on the amplification of esat-6 gene, comprising isolating DNA template from the sample, amplifying with the above oligonucleotide primer pair and subjecting the amplified DNA product to separation and staining to detect the presence of amplified DNA product for identifying Mycobacterium tuberculosis in the sample. The invention further provides a diagnostic kit for detection of Mycobacterium tuberculosis.

Abstract: Oligonucleotide primers for specific amplification of the hupB gene of Mycobacterium species selected from the group consisting of Seq ID No. 1, Seq ID No. 2, Seq ID No. 3, Seq ID No. 4, Seq ID No. 5 and a method for differentiating Mycobacterium species based on target gene encoding for histone like proteins such as hupB comprising of (a) obtaining DNA from culture or from clinical samples, b) amplifying a part of the target gene encoding for histone like proteins such as hupB of Mycobacterium species using DNA as a template in a polymerise chain reaction with a pair of oligonucleotide primers, c) detecting said amplified fragment of the hupB gene to detect the presence of Mycobacterial species or not and differentiating Mycobacterium tuberculosis from Mycobacterium bovis based on the size of the amplified fragment.

Abstract: The present invention relates to analysis of the alterations in p21waf1/cip1 gene and its expression in relation to p53 status in esophageal cancer, a method for screening of subjects having or at risk of having esophageal cancer by detection of the polymorphism in p21waf1/cip1 gene, and use thereof as a diagnostic marker.

Abstract: Aspermatogenesis is achieved in mammalian species without disturbance of libido and hormone level by intratesticular injection of Bacillus of Calmette and Guerin. The procedure is applicable to a wide variety of mammalian species.

Abstract: A vaccine comprising a conjugate of an antigenic carrier with beta sub-unit of human chorionic gonadotropin, or derivatives or fragments thereof, purified by procedures which minimize cross-reactivity with LH, such as immunosorption with heterologous LH antiserum prior to conjugation, and a process for making the vaccine. In addition, a process for preventing pregnancy using said vaccine is described.