Abstract: Pump priming systems and chromatography systems containing the same are, disclosed. Methods of making and methods of using pump priming systems are also disclosed. In conventional chromatography instrumentation, pump priming is performed in a manual mode where the operator manually opens a mechanical valve and uses a syringe to move liquid through the pump until the lines and the pump are filled with liquid.
Type:
Application
Filed:
October 25, 2013
Publication date:
September 24, 2015
Applicant:
Alltech Associates, Inc.
Inventors:
Romulus Gaita, Washington Mendoza, James Anderson, JR., Melissa Golde, Raaidah Saari-Nordhaus
Abstract: Chromatography systems and components suitable for use in chromatography systems are disclosed. Methods of making chromatography systems and components suitable for use in chromatography systems and methods of using chromatography systems and components suitable for use in chromatography systems are also disclosed.
Type:
Grant
Filed:
December 10, 2009
Date of Patent:
July 21, 2015
Assignee:
Alltech Associates, Inc.
Inventors:
Josef Bystron, Dirk Helgemo, James Anderson, Jr., Washington Mendoza, Raaidah Saari-Nordhaus, Steve Lewis, Sheldon Nelson, Bruce Frohman, Nick Klein
Abstract: Automated sample injection apparatus, multiport valves, and chromatography systems containing an automated sample injection apparatus and/or a multiport valve are disclosed. Methods of making and using automated sample injection apparatus and multiport valves within chromatography systems are also disclosed.
Type:
Application
Filed:
January 9, 2015
Publication date:
May 7, 2015
Applicant:
Alltech Associates, Inc.
Inventors:
Raaidah Saari-Nordhaus, Washington Mendoza, Josef Bystron, Neil Picha, Bruce Black
Abstract: Components suitable for use in an evaporative light scattering detector and other devices are disclosed. Methods of making and using components suitable for use in an evaporative light scattering detector and other devices are also disclosed.
Type:
Grant
Filed:
February 27, 2007
Date of Patent:
March 25, 2014
Assignee:
Alltech Associates, Inc.
Inventors:
Raaidah B. Saari-Nordhaus, Washington J. Mendoza, Michael F. Wicnienski, Alexandra M. Kuch, James M. Anderson
Abstract: The present invention relates to a chromatographic method of separating biological material comprising, providing chromatographic media comprising inorganic oxide particles having an average diameter of about 2 microns or less and an average pore diameter of 300 ? or more; applying a solvent comprising said biological material to said media, wherein said biological material is reversibly bonded to said media; and eluting said biological material from said media with a solvent in less than about 2 minutes for biological material having a molecular weight of less than about 100,000 Daltons.
Type:
Grant
Filed:
February 21, 2008
Date of Patent:
November 12, 2013
Assignee:
Alltech Associates, Inc.
Inventors:
Reno T. Nguyen, Scott Anderson, Ian Chappell
Abstract: Chromatography columns are disclosed. Methods of making chromatography columns and methods of using chromatography columns are also disclosed.
Abstract: Methods and apparatus for analyzing a sample using at least one detector are disclosed.
Type:
Grant
Filed:
December 4, 2008
Date of Patent:
February 14, 2012
Assignee:
Alltech Associates, Inc.
Inventors:
James M. Anderson, Jr., Raaidah B. Saari-Nordhaus, Washington J. Mendoza, Josef P. Bystron, Dirk Helgemo, Sheldon Nelson, Bruce D. Black, Neil R. Picha, Dennis K. Mc Creary, Carl H. Poppe
Abstract: The present invention is directed to a system for converting between single flow and split flow evaporative light scattering detection devices for detecting samples in a mobile phase. Included in the system is a evaporative light scattering detection device, a low temperature adaptor, and a connection tube for providing a fluid connection between the evaporative light scattering detection device and the low temperature adaptor.
Type:
Grant
Filed:
September 7, 1999
Date of Patent:
February 28, 2006
Assignee:
Alltech Associates, Inc.
Inventors:
James M. Anderson, Jr., Raaidah Saari-Nordhaus, Bart C. Benedict, Melissa Wilcox, Ronald Krob, Arnold Williams
Abstract: The present invention relates to a solid and method useful in separating chemical components in a complex mixture when at least one of the chemical components of the mixture is capable of being selectively adsorbed. The solid of the present invention comprises an inorganic substance and moieties (R10) located on at least one surface of the inorganic substance, wherein said inorganic substance is an inorganic oxide and the surface moiety is selected from the group consisting of —CH2OH, —CH(OH)2, —CH(OH)CH3, —CH2CH2OH, —C(OH)2CH3, —CH2CH(OH)2 and —CH(OH)CH2(OH). Binding moiety, optionally attached to the inorganic substance via a linker, can also be located on the surface of the solid.
Abstract: A method and apparatus is provided for generating a high purity eluant suitable for use in chromatography. The high purity eluant may be generated by providing water and a first stationary phase comprising exchangeable cations. Electrolysis ions are generated by the electrolysis of water. The electrolysis ions are selected from the group consisting of hydronium ions and hydroxide ions. The hydronium ions are passed through the first stationary phase so that the hydronium ions replace the cations in the first stationary phase. Thereafter, a source of desired ions is combined with the cations to form a high purity eluant containing the desired ions.
Type:
Application
Filed:
April 23, 2003
Publication date:
October 28, 2004
Applicant:
Alltech Associates, Inc.
Inventors:
James M. Anderson, Raaidah Saari-Nordhaus
Abstract: An ion exchange chromatography apparatus includes a first stationary phase and a second stationary phase. The first stationary phase has at least one complexing agent functional group capable of forming a complex with at least one ion present in a sample that contains at least two ions when the sample contacts the first stationary phase. The second stationary phase is distinct from the first stationary phase and has at least one non-complexing agent functional group capable of exchanging with the ions present in the sample, other than the one complexed by the complexing agent functional group.
Type:
Grant
Filed:
April 28, 2003
Date of Patent:
July 6, 2004
Assignee:
Alltech Associates, Inc.
Inventors:
James M. Anderson, Jr., Raaidah Saari-Nordhaus
Abstract: An integrated suppressor and detector for suppressed ion chromatography includes a stationary phase, a fluid flow path, at least first and second regeneration electrodes, and at least first and second sensor electrodes. Methods of suppressed ion chromatography using the integrated suppressor and detector are also described.
Type:
Grant
Filed:
April 8, 2003
Date of Patent:
March 23, 2004
Assignee:
Alltech Associates, Inc.
Inventors:
James M. Anderson, Jr., Raaidah Saari-Nordhaus