Patents Assigned to Amano Enzyme Inc.
  • Oxidoreductase reaction control and use thereof
    Patent number: 9777299
    Abstract: The present invention is intended to prove a technique useful for controlling the reaction of oxidoreductase, and to provide a reaction system allowing efficient conversion from carbon dioxide to formic acid, and an efficient methanol production system including the reaction system. The reverse redox reaction is selectively promoted by carrying out the reaction catalyzed by an oxidoreductase using an artificial electron carrier. The reaction system is used for the production of methanol.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: October 3, 2017
    Assignee: AMANO ENZYME INC.
    Inventors: Yutaka Amao, Shusaku Ikeyama, Yuji Nakanishi, Tetsuya Takahashi, Satoshi Koikeda
  • MODIFIED ß-GALACTOSIDASE
    Publication number: 20170233705
    Abstract: The present invention has a purpose of providing a technique for increasing the heat resistance of a ?-galactosidase. According to the present invention, in a reference ?-galactosidase amino acid sequence which shows a 90% or more identity to the amino acid sequence of SEQ ID NO: 4, proline is substituted for one or more amino acids selected from the group consisting of the following amino acids: (1) an amino acid corresponding to lysine at position 166 of the amino acid sequence of SEQ ID NO: 4, (2) an amino acid corresponding to glycine at position 307 of the amino acid sequence of SEQ ID NO: 4, and (3) an amino acid corresponding to alanine at position 833 of the amino acid sequence of SEQ ID NO: 4.
    Type: Application
    Filed: August 13, 2015
    Publication date: August 17, 2017
    Applicant: Amano Enzyme Inc.
    Inventors: Kazuhiko Ishikawa, Satoru Ishihara, Shotaro Yamaguchi
  • Microbial-derived chondroitin sulfate
    Patent number: 9689010
    Abstract: Described is chondroitin sulfate obtained from microbial sources, and related compositions and methods.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: June 27, 2017
    Assignees: AMANO ENZYME USA, LTD., AMANO ENZYME, INC.
    Inventors: James F. Jolly, Krzysztof Klimaszewski, Yuji Nakanishi, Hirotaka Matsubara, Tetsuya Takahashi, Kyouichi Nishio
  • SACCHARIDE OXIDASE, AND PRODUCTION METHOD FOR SAME AND USE OF SAME
    Publication number: 20170137788
    Abstract: A protein having a novel saccharide oxidase activity capable of being subjected to various uses is provided. The present invention provides a protein having the following physicochemical characteristics: (1) effect: oxidizing a saccharide to produce a saccharic acid; (2) substrate specificity: acting on glucose, maltotriose, maltose, galactose, maltotetraose, lactose, and cellobiose; and, (3) [Km value of glucose]/[Km value of maltose]?1.
    Type: Application
    Filed: January 23, 2017
    Publication date: May 18, 2017
    Applicant: AMANO ENZYME INC.
    Inventors: Miho NAGAYA, Akiko SUGITA, Naoki MATSUMOTO, Masamichi OKADA
  • Modified alpha-glucosidase and applications of same
    Patent number: 9650619
    Abstract: The object is to provide an ?-glucosidase in which a transglycosylation activity predominates, and use thereof, and the like. A modified ?-glucosidase consisting of an amino acid sequence in which one or two or more of the amino acid(s) is selected from a group of specific amino acids.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: May 16, 2017
    Assignee: AMANO ENZYME INC.
    Inventor: Satoru Ishihara
  • Beta-galactosidase derived from
    Patent number: 9516888
    Abstract: Disclosed is a novel ?-galactosidase. Specifically disclosed are a ?-galactosidase derived from Bacillus circulans and a gene for the ?-galactosidase. The ?-galactosidase can be used, for example, in the production of milk, dairy products, fermented dairy products, galacto-oligosaccharides or supplements for foods.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: December 13, 2016
    Assignee: AMANO ENZYME INC.
    Inventors: Toru Katase, Yukiko Hoshi, Miho Nagaya, Shotaro Yamaguchi, Masashi Minoda, Kazuhiro Nakanishi
  • Use of proteases for gluten intolerance
    Patent number: 9498520
    Abstract: The present technology relates to an enzyme composition. The enzyme composition may be used to treat gluten intolerant subjects, including suffering from non-Celiac gluten intolerance and/or non-Celiac gluten sensitivity. The enzyme composition may also be used to reduce gluten exposure in certain individuals. For example, the enzyme composition may also be used as a prophylactic to reduce exposure to gluten oligopeptides.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: November 22, 2016
    Assignees: AMANO ENZYME INC., AMANO ENZYME USA CO. LTD.
    Inventors: James F. Jolly, Horoki Ido, Hirotaka Matsubara, Tetsuya Takahashi, Kyoichi Nishio
  • Modified ?-glucosidase and applications of same
    Patent number: 9493753
    Abstract: The object is to provide an ?-glucosidase in which a transglycosylation activity predominates, and use thereof, and the like. A modified ?-glucosidase consisting of an amino acid sequence in which one or two or more of the amino acid(s) is selected from a group of specific amino acids.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: November 15, 2016
    Assignee: AMANO ENZYME INC.
    Inventor: Satoru Ishihara
  • Stabilized transglutaminase and process for production thereof
    Patent number: 9487765
    Abstract: Disclosed is a transglutaminase having excellent stability. Also disclosed is a process for producing the transglutaminase. Specifically disclosed is a stabilized transglutaminase, which has such a structure in which a pro-sequence peptide of transglutaminase is bound to a mature transglutaminase. Also specifically disclosed is a process for producing stabilized transglutaminase, which includes the steps of culturing a microorganism capable of producing transglutaminase under the conditions where transglutaminase can be produced; and separating and collecting matured transglutaminase having a pro-sequence peptide bound thereto from a culture medium.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: November 8, 2016
    Assignee: AMANO ENZYME INC.
    Inventors: Masamichi Okada, Yoshiaki Kurono, Hitoshi Amano, Shotaro Yamaguchi
  • Mutant enzyme and application thereof
    Patent number: 9458434
    Abstract: An object is to provide a novel enzyme that exhibits glucose dehydrogenase activity. Furthermore, another object is to provide a novel method pertaining to enzyme modification. Provided is a mutated enzyme containing an amino acid sequence wherein one or at least two amino acids selected from a group are substituted with another amino acid in the amino acid sequence of a microorganism-derived glucose oxidase.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: October 4, 2016
    Assignee: AMANO ENZYME INC.
    Inventors: Kyoichi Nishio, Satoshi Koikeda
  • Method of classifying antibody, method of identifying antigen, method of obtaining antibody or antibody set, method of constructing antibody panel and antibody or antibody set and use of the same
    Patent number: 9388249
    Abstract: The present invention relates to an isolated antibody against HER1, an isolated antibody against CD147, an isolated antibody against CD73, and an isolated antibody against EpCAM; reagents and compositions including said antibodies; and uses of said reagents, compositions, and antibodies. The present invention also relates to nucleic acids and vectors expressing said antibodies. The invention further relates to transformants comprising said nucleic acids or vectors.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: July 12, 2016
    Assignee: AMANO ENZYME INC.
    Inventors: Atsushi Sugioka, Gene Kurosawa, Mariko Sumitomo, Yoshikazu Kurosawa
  • Dyeing of keratin fibers using indole analogue
    Patent number: 9358198
    Abstract: The problem is to provide a means for effectively dyeing keratin fibers while retaining high safety. Provided are a dyeing method and a dyeing agent, which include a combination of an oxidation dyeing agent consisting of an indole analog and a bilirubin oxidase derived from Myrothecium verrucaria or Bacillus Subtilis.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: June 7, 2016
    Assignee: AMANO ENZYME INC.
    Inventors: Yukihide Sato, Yoshihiko Hirose
  • MICROBIAL-DERIVED CHONDROITIN SULFATE
    Publication number: 20160024544
    Abstract: Described is chondroitin sulfate obtained from microbial sources, and related compositions and methods.
    Type: Application
    Filed: July 8, 2015
    Publication date: January 28, 2016
    Applicants: Amano Enzyme USA., Ltd., Amano Enzyme, Inc.
    Inventors: James F. Jolly, Krzysztof Klimaszewski, Yuji Nakanishi, Hirotaka Matsubara, Tetsuya Takahashi, Kyouichi Nishio
  • Reducing agent from microorganism belonging to genus and application for same
    Patent number: 9241507
    Abstract: The present invention is intended to provide a reducing agent effective for color development of meat and uses therefor. The present invention provides a reducing agent containing a heme reductase derived from a microorganism belonging to the genus Bacillus. Preferably, crushed bacterial cells of Bacillus subtilis, Bacillus amyloliquefaciens, Bacillus natto, Bacillus thuringiensis, or Bacillus mycoides are used.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: January 26, 2016
    Assignee: Amano Enzyme Inc.
    Inventors: Keita Okuda, Shotaro Yamaguchi
  • Stabilized transglutaminase and process for production thereof
    Patent number: 9217141
    Abstract: Disclosed is a transglutaminase having excellent stability. Also disclosed is a process for producing the transglutaminase. Specifically disclosed is a stabilized transglutaminase, which has such a structure in which a pro-sequence peptide of transglutaminase is bound to a mature transglutaminase. Also specifically disclosed is a process for producing stabilized transglutaminase, which includes the steps of: culturing a microorganism capable of producing transglutaminase under the conditions where transglutaminase can be produced; and separating and collecting matured transglutaminase having a pro-sequence peptide bound thereto from a culture medium.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: December 22, 2015
    Assignee: Amano Enzyme Inc.
    Inventors: Masamichi Okada, Yoshiaki Kurono, Hitoshi Amano, Shotaro Yamaguchi
  • Beta-amylase, gene coding therefor and manufacturing method thereof
    Patent number: 9157074
    Abstract: To provide novel ?-amylase derived from a microorganism and a gene thereof. ?-amylase derived from Bacillus flexus is provided.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: October 13, 2015
    Assignee: Amano Enzyme Inc.
    Inventors: Akiko Matsunaga, Hitoshi Amano, Shotaro Yamaguchi
  • Enzymatic methods of flavor modification
    Patent number: 9144249
    Abstract: Described are enzymatic methods of making food products and modifying food flavor using, for example, a lipase and a lactase, and related enzyme compositions and food products.
    Type: Grant
    Filed: June 22, 2009
    Date of Patent: September 29, 2015
    Assignees: AMANO ENZYME USA, LTD., AMANO ENZYME, INC.
    Inventor: James F. Jolly
  • SACCHARIDE OXIDASE, AND PRODUCTION METHOD FOR SAME AND USE OF SAME
    Publication number: 20150232813
    Abstract: A protein having a novel saccharide oxidase activity capable of being subjected to various uses is provided. The present invention provides a protein having the following physicochemical characteristics: (1) effect: oxidizing a saccharide to produce a saccharic acid; (2) substrate specificity: acting on glucose, maltotriose, maltose, galactose, maltotetraose, lactose, and cellobiose; and, (3) [Km value of glucose]/[Km value of maltose]?1.
    Type: Application
    Filed: September 13, 2013
    Publication date: August 20, 2015
    Applicant: AMANO ENZYME INC.
    Inventors: Miho Nagaya, Akiko Sugita, Naoki Matsumoto, Masamichi Okada
  • Microbial-derived chondroitin sulfate
    Patent number: 9109243
    Abstract: Described is chondroitin sulfate obtained from microbial sources, and related compositions and methods.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: August 18, 2015
    Assignees: AMANO ENZYME USA, LTD., AMANO ENZYME, INC.
    Inventors: James F. Jolly, Krzysztof Klimaszewski, Yuji Nakanishi, Hirotaka Matsubara, Tetsuya Takahashi, Kyouichi Nishio
  • Beta-amylase, gene coding therefor and manufacturing method thereof
    Patent number: 9090886
    Abstract: To provide novel ?-amylase derived from a microorganism and a gene thereof. ?-amylase derived from Bacillus flexus is provided.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: July 28, 2015
    Assignee: Amano Enzyme Inc.
    Inventors: Akiko Matsunaga, Hitoshi Amano, Shotaro Yamaguchi