Patents Assigned to Ambrx, Inc.
  • Compositions Containing, Methods Involving, and Uses of Non-Natural Amino Acids and Polypeptides
    Publication number: 20080118464
    Abstract: Disclosed herein are non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of possible functionalities, but typical have at least one aromatic amine group. Also disclosed herein are non-natural amino acid polypeptides that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such polypeptides. Typically, the modified non-natural amino acid polypeptides include at least one alkylated amine group. Further disclosed are methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses.
    Type: Application
    Filed: October 26, 2007
    Publication date: May 22, 2008
    Applicant: AMBRX, INC.
    Inventors: Zhenwei Miao, Junjie Liu, Thea Norman
  • Human Interferon Molecules and Their Uses
    Publication number: 20080119640
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 26, 2007
    Publication date: May 22, 2008
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria A. HAYS, Bruce E. KIMMEL, Ho Sung CHO, Bee-Cheng SIM, David C. LITZINGER, Roberto MARIANI, Vadim KRAYNOV, Nick Knudsen, Thomas O. DANIEL, Alan KODER, Stuart BUSSELL, Junjie LIU, Zhenwei MIAO, Theresa MORROW
  • Formulations of Human Growth Hormone Comprising a Non-Naturally Encoded Amino Acid
    Publication number: 20080113912
    Abstract: Formulations of modified human growth hormone polypeptides are provided.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria HAYS, Ying BUECHLER, David C. LITZINGER
  • Modified Human Interferon Polypeptides and Their Uses
    Publication number: 20080114155
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Anna-Maria HAYS, Troy WILSON
  • Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses
    Publication number: 20080113412
    Abstract: Modified human plasma polypeptides or Fc and uses thereof are provided.
    Type: Application
    Filed: October 29, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Joseph SHEFFER, Thea NORMAN, Richard D. DIMARCHI, Anna-Maria A. HAYS PUTNAM, Feng TIAN, Stephanie CHU, Denise KRAWITZ, Ho Sung CHO
  • Modified Human Interferon Polypeptides and Their Uses
    Publication number: 20080114154
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho CHO, Thomas DANIEL, Anna-Maria HAYS, Troy WILSON
  • Formulations of Human Growth Hormone Comprising a Non-Naturally Encoded Amino Acid
    Publication number: 20080113913
    Abstract: Formulations of modified human growth hormone polypeptides are provided.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria HAYS, Ying BUECHLER, David C. LITZINGER
  • Biosynthetic Polypeptide Fusion Inhibitors
    Publication number: 20080112943
    Abstract: Modified biosynthetic polypeptide fusion inhibitors, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Roberto MARIANI, Bruce E. KIMMEL
  • Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses
    Publication number: 20080113411
    Abstract: Modified human plasma polypeptides or Fc and uses thereof are provided.
    Type: Application
    Filed: October 29, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Joseph SHEFFER, Thea NORMAN, Richard D. DIMARCHI, Anna-Maria A. HAYS PUTNAM, Feng TIAN, Stephanie CHU, Denise KRAWITZ, Ho Sung CHO
  • Formulations of Human Growth Hormone Comprising a Non-Naturally Encoded Amino Acid
    Publication number: 20080113914
    Abstract: Formulations of modified human growth hormone polypeptides are provided.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria HAYS, Ying BUECHLER, David C. LITZINGER
  • Biosynthetic Polypeptide Fusion Inhibitors
    Publication number: 20080113408
    Abstract: Modified biosynthetic polypeptide fusion inhibitors, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Roberto MARIANI, Bruce E. KIMMEL
  • Modified Human Growth Hormone
    Publication number: 20080107680
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 8, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung Cho, Thomas Daniel, Richard DiMarchi, Anna-Maria Hays, Troy Wilson, Bee-Cheng Sim, David Litzinger
  • Modified Human Growth Hormone Polypeptides and Their Uses
    Publication number: 20080108797
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 8, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Richard DIMARCHI, Anna-Maria HAYS, Troy WILSON, Bee-Cheng SIM, David LITZINGER
  • Modified Human Interferon Polypeptides and Their Uses
    Publication number: 20080108791
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 8, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho CHO, Thomas DANIEL, Anna-Maria HAYS, Troy WILSON
  • Human Interferon Molecules and Their Uses
    Publication number: 20080108792
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 26, 2007
    Publication date: May 8, 2008
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria Hays, Bruce Kimmel, Ho Sung Cho, Bee-Cheng SIM, David Litzinger, Roberto Mariani, Vadim Kraynov, Nick Knudsen, Thomas Daniel, Alan Koder, Stuart Bussell, Junjie Liu, Zhenwei Miao, Theresa Morrow
  • Modified Human Growth Hormone
    Publication number: 20080102124
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 1, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Richard DIMARCHI, Anna-Maria HAYS, Troy WILSON, Bee-Cheng SIM, David LITZINGER
  • Modified Human Growth Hormone Polypeptides and Their Uses
    Publication number: 20080103294
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 1, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Richard DIMARCHI, Anna-Maria HAYS, Troy WILSON, Bee-Cheng SIM, David LITZINGER
  • Modified Human Growth Hormone
    Publication number: 20080102125
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Application
    Filed: October 25, 2007
    Publication date: May 1, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Richard DIMARCHI, Anna-Maria HAYS, Troy WILSON, Bee-Cheng SIM, David LITZINGER
  • Modified Human Growth Hormone Polypeptides and Their Uses
    Publication number: 20080103293
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 1, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Richard DIMARCHI, Anna-Maria HAYS, Troy WILSON, Bee-Cheng SIM, David LITZINGER
  • Modified Human Four Helical Bundle Polypeptides and Their Uses
    Publication number: 20080097083
    Abstract: Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 18, 2007
    Publication date: April 24, 2008
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas DANIEL, Richard DIMARCHI, Anna-Maria HAYS, Troy WILSON, Bee-Cheng SIM, David LITZINGER