Patents Assigned to American Cyanamid
  • Patent number: 6284762
    Abstract: The novel compounds of formula I: (R1, R2, R3, L1, L2 and Hal are defined in the specification) show selective fungicidal activity. These compounds may be processed with carriers, and optionally an adjuvant, to produce fungicidal compositions.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: September 4, 2001
    Assignee: American Cyanamid Company
    Inventor: Waldemar Pfrengle
  • Patent number: 6284519
    Abstract: This invention relates to novel modified host cells which express heterologous fused proteins and methods of screening for test samples having peptide-binding activity; wherein the modified host cell comprises: (a) a gene sequence encoding a heterologous fusion protein; said fusion protein comprising a first peptide of a peptide binding pair, or segment of said first peptide, which is joined to either a DNA binding domain or its corresponding transcriptional activation domain of a transcriptional activation protein; (b) a gene sequence encoding a heterologous fusion protein, said fusion protein comprising a second peptide of the peptide binding pair in (a), or a segment thereof, fused to either a DNA binding domain or its corresponding transcriptional activation domain, whichever one is not employed in (a); (c) a reporter gene operatively associated with the transcriptional activation protein, or a portion thereof; (d) optionally, a deletion or mutation in the chromosomal DNA of the host cell for the transcri
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: September 4, 2001
    Assignee: American Cyanamid Company
    Inventors: Kathleen H. Young, Bradley A. Ozenberger
  • Patent number: 6284256
    Abstract: The present invention is concerned with a vaccine for combating B. bronchiseptica infection in susceptible animals (such as dogs and swine), containing proteins or polypeptides typical of the fimbrial protein of B. bronchiseptica, or containing recombinant polynucleotides having as part thereof a polynucleotide coding for the protein or polypeptide, and also is concerned with the preparation of said proteins, polypeptides and polynucleotides.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: September 4, 2001
    Assignee: American Cyanamid Company
    Inventors: Paul Savelkoul, Willem Gaastra
  • Patent number: 6281168
    Abstract: The invention relates to methods for protecting cereal crops from injury caused by a herbicidally effective amount of a herbicide, in particular, herbicides selected from the group consisting of AHAS-inhibiting, ACCase-inhibiting and HPPD-inhibiting herbicides, which comprises applying to the crop plant, the seed of the crop, or the soil surrounding the crop or crop seed an effective non-phytotoxic antidotal amount of a benzothiazole derivative of formula I wherein A represents an alkyl, alkoxy, haloalkoxy, hydroxy, cyano or nitro group or a group of the formula  in which W represents O or S, and R represents a hydroxy, thiol, alkoxy, thioalkyl, amino, alkylamino or dialkylamino group; and X represents CH or N; Also included are safened herbicidal compositions comprising a herbicidally effective amount of a herbicide and an effective nonphytotoxic antidotal amount a benzothiazole derivative of formula I.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: August 28, 2001
    Assignee: American Cyanamid Co.
    Inventors: Dale Lester Shaner, Helmut Siegfried Baltruschat, Norbert Nelgen
  • Patent number: 6281219
    Abstract: The present invention provides compounds of Formula I methods for their preparation and their use as acaricidal and insecticidal agents.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: August 28, 2001
    Assignee: American Cyanamid Co.
    Inventors: Salvatore John Cuccia, William Wakefield Wood, Brian Lee Buckwalter, John Francis Chiarello, Linda Barbara Fleming
  • Patent number: 6281358
    Abstract: The invention relates to a process for the preparation of substituted pyrimidines of formula I, wherein R1, R2, R3, R4 and X are as defined in claim 1, which comprises reacting an amidine of formula II, or a salt thereof, with a 3,3-disubstituted vinylcarbonyl compound of formula III wherein L represent a halogen atom or a group of formula —X—R2, (a) in an inert solvent, in the presence of a base and a compound of formula IV H—X—R2  (IV) in the event that L represent a halogen atom, or (b) in an inert solvent and in the presence of a base, in the event that L represents a group of formula —X—R2.
    Type: Grant
    Filed: April 12, 2000
    Date of Patent: August 28, 2001
    Assignee: American Cyanamid Company
    Inventors: Oliver Meyer, Dieter Gutheil
  • Patent number: 6281365
    Abstract: Organic platinum complexes active as anti-tumor agents in warm-blooded animals, and methods for synthesis of same, are described.
    Type: Grant
    Filed: May 26, 1989
    Date of Patent: August 28, 2001
    Assignee: American Cyanamid Company
    Inventors: Ralph Grassing Child, Panayota Bitha, Joseph John Hlavka, Yang-I Lin
  • Patent number: 6277885
    Abstract: Hydroxamic acids having the formula are useful in treating disease conditions mediated by TNF-&agr;, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: August 21, 2001
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, James M. Chen
  • Patent number: 6277857
    Abstract: The novel compounds of formula I: wherein (R1, R2, R3, A, X, L and n through L5 are defined in the specification) show high fungicidal activity. The new compounds are processed with carriers and adjuvants to fungicidal compositions.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: August 21, 2001
    Assignee: American Cyanamid Company
    Inventors: Waldemar Pfrengle, Klaus-Juergen Pees
  • Patent number: 6277787
    Abstract: The present invention provides a method for the synergistic control of undesirable plants such as Ipomoea, Cyperus, Sida and Euphorbia which comprises applying to the plants or their locus a synergistically effective amount of a combination of glyphosate and an imidazolinone compound. Further provided are synergistic herbicidal compositions comprising glyphosate and an imidazolinone compound.
    Type: Grant
    Filed: September 14, 1999
    Date of Patent: August 21, 2001
    Assignee: American Cyanamid Co.
    Inventors: Timothy Malefyt, Robert M. Watkins, Frederick P. Salzman
  • Publication number: 20010011064
    Abstract: The invention relates to novel compounds of formula I: 1
    Type: Application
    Filed: January 12, 2001
    Publication date: August 2, 2001
    Applicant: American Cyanamid Company
    Inventors: Thomas Maier, Stefan Scheiblich, Helmut S. Baltruschat
  • Patent number: 6268371
    Abstract: The invention relates to fungicidal composition comprising an acceptable carrier and/or surface active agent and synergistically effective amounts of (a) at least one azolopyrimidine of formula I  in which R1 through R2, L, A and n have the meaning given in claim 1; (b) and at least one melanin biosynthesis inhibitor (MBI), preferably a phenoxyamide of formula II  wherein R5 through R9, Y and m have the meaning given in claim 2; and to a method of controlling the growth of phythopathogenic fungi at a locus which comprises applying synergistically effective amounts of at least one azolopyrimidine of formula I (a) and at least one MBI (b) to the locus.
    Type: Grant
    Filed: September 9, 1999
    Date of Patent: July 31, 2001
    Assignee: American Cyanamid Co.
    Inventors: Ewald Sieverding, Leslie May
  • Patent number: 6263928
    Abstract: A container for use in a closed application system includes a valve mounted to a discharge opening of the container and rotatable with the container for controlling the discharge of material from the container. The valve includes an element for engaging corresponding structure in a receptacle for receiving the contents of the container. The element engages and locks the valve in the receptacle when the valve is opened and the contents are being discharged from the container into the receptacle. The valve element and the corresponding structure on the receptacle cooperate so that the container can only be received in and removed from the receptacle when the valve is closed. In this manner, the contents in the container can be discharged only when the container is received within the receptacle and the container is rotated in a direction to open the valve.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: July 24, 2001
    Assignee: American Cyanamid Company
    Inventor: Keith F. Woodruff
  • Patent number: 6262319
    Abstract: A process and intermediate compounds for the preparation of fluoroolefin compounds which are useful as pesticidal agents.
    Type: Grant
    Filed: December 21, 1998
    Date of Patent: July 17, 2001
    Assignee: American Cyanamid Co.
    Inventors: Keith Douglas Barnes, Yulin Hu, David Allen Hunt
  • Patent number: 6251602
    Abstract: This invention relates to novel modified host cells which express heterologous fused proteins and methods of screening for test samples having peptide-binding activity; wherein the modified host cell comprises: (a) a gene sequence encoding a heterologous fusion protein; said fusion protein comprising a first peptide of a peptide binding pair, or segment of said first peptide, which is joined to either a DNA binding domain or its corresponding transcriptional activation domain of a transcriptional activation protein; (b) a gene sequence encoding a heterologous fusion protein, said fusion protein comprising a second peptide of the peptide binding pair in (a), or a segment thereof, fused to either a DNA binding domain or its corresponding transcriptional activation domain, whichever one is not employed in (a); (c) a reporter gene operatively associated with the transcriptional activation protein, or a portion thereof; (d) optionally, a deletion or mutation in the chromosomal DNA of the host cell for the transcri
    Type: Grant
    Filed: March 8, 1999
    Date of Patent: June 26, 2001
    Assignee: American Cyanamid Company
    Inventors: Kathleen H. Young, Bradley A. Ozenberger
  • Patent number: 6251397
    Abstract: The present invention provides a purified preparation containing, for example, a polynucleic acid encoding at least one polypeptide selected from the group consisting of proteins encoded by one or more open reading frames (ORF's) of an Iowa strain of porcine reproductive and respiratory syndrome virus (PRRSV), antigenic regions of such proteins which are at least 5 amino acids in length and which effectively protect a porcine host against a subsequent challenge with a PRRSV isolate, and combinations thereof in which amino acids non-essential for antigenicity may be conservatively substituted. The present invention also concerns a polypeptide encoded by such a polynucleic acid; a vaccine comprising an effective amount of such a polynucleic acid or protein; antibodies which specifically bind to such a polynucleic acid or protein; methods of producing the same; and methods of protecting a pig against a PRRSV and treating a pig infected by a PRRSV.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 26, 2001
    Assignees: Iowa State University Research Foundation, Inc., American Cyanamid Company
    Inventors: Prem S. Paul, Xiang-Jin Meng, Patrick Halbur, Igor Morozov
  • Patent number: 6251912
    Abstract: This invention provides compounds of formula 1 having the structure wherein: X, R1, R2, R3, R4, Z, X, and n are as defined hereinbefore in the specification, which are useful as antineoplastic agents and in the treatment of certain kidney diseases, such as polycystic kidney disease.
    Type: Grant
    Filed: July 29, 1998
    Date of Patent: June 26, 2001
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Hwei-Ru Tsou, Bernard D. Johnson, Philip R. Hamann, Nan Zhang
  • Patent number: 6242647
    Abstract: The present invention provides N-biphenylthiohydrazone derivatives of formula I and compositions and methods for the use thereof in the control of insect and acarid pests and for the protection of crops therefrom.
    Type: Grant
    Filed: December 3, 1998
    Date of Patent: June 5, 2001
    Assignee: American Cyanamid Company
    Inventors: Robert Eugene Diehl, David Allen Hunt, Susan Hensen Trotto
  • Patent number: 6242613
    Abstract: The present invention relates to arylpyrrole particles which are prepared by a process in which the particles are aged and milled, and pesticidal suspension concentrate compositions comprising them. The size of the particles of this invention remains surprisingly stable during storage.
    Type: Grant
    Filed: April 6, 1999
    Date of Patent: June 5, 2001
    Assignee: American Cyanamid Co.
    Inventors: Mimi Yih-Pei Chou Schaaf, Steven Brunt, Jian James Xu, Andrew Evelyn Goldsmith, Anthony Francis Walker, Patrick C. Mowery, Edward S. Donoghue, Srinivasan Rajan
  • Patent number: 6235762
    Abstract: The present invention relates to 2-aryl-&Dgr;2-1,3,4-(oxa and thia)diazoline compounds having the structural formula and compositions and methods comprising those compounds for the control of insect and acarid pests.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: May 22, 2001
    Assignee: American Cyanamid Company
    Inventors: James Jan Takasugi, Brian Lee Buckwalter