Abstract: A method of treating dermal inflammation by topically administering to a patient an effective amount of a condensed pyrrole bearing a N-phenyl substituent and compositions containing an aforesaid pyrrole are described.

Abstract: Novel piperazinoalkylpyrrolobenzoxazalkanes, physiologically tolerable acid addition salts thereof and a method of preparing same are described. These compounds are useful as antihypertensive agents.

Abstract: New benzoylpiperidylalkylindoles and related compounds possessing tranquilizing, anti-hypertensive and analgesic properties and a process for the preparation thereof are described.

Abstract: Novel pyrrolobenzoxazalkanes, physiologically tolerable acid addition salts thereof and a method of preparing same are described. Compounds of the present invention are useful as analgesic, tranquilizing and anticonvulsant agents.

Abstract: Processing additives are incorporated in polyvinyl chloride resin by preparing an additive concentrate in free-flowing powder form and mixing an aliquot portion thereof with a batch of polyvinyl chloride powder in a high shear mixer to form a molding composition containing the additives in the desired proportions. The additive concentrate is made by preparing an aqueous emulsion of the lubricants and stabilizers which is then mixed with solid additives such as pigments and fillers to form the free-flowing additive concentrate powder. By using the additive concentrate the need for individual weighing of each additive to be added to each batch of polyvinyl chloride resin is avoided.

Abstract: Processing additives are incorporated in polyvinyl chloride resins to form molding compositions by preparing an aqueous emulsion wherein the additives such as lubricants and stabilizers are in the disperse phase and then mixing an aliquot portion of the emulsion with a polyvinyl chloride resin powder in a high shear mixer to incorporate the additives in the resin in the proper proportions. By using an aqueous emulsion of the additives, the need for separately weighing each additive to be added to each batch of polyvinyl chloride is avoided and uniform dispersion of the additives in the resin achieved. The heat generated during the mixing process evaporates most of the water of the emulsion and the relatively small amount of retained water improves the anti-static properties of the molding composition.

Abstract: A novel method for the preparation of 4-bromo-1,8-naphthalic acid anhydride is disclosed. This method is carried out by the bromination, with alkali metal bromide or molecular bromine in the presence of a hypohalite, of a di-alkali metal salt of 1,8-naphthalic acid in aqueous solution at a pH of between 6.5 and 9.5 and at a temperature of between 0.degree. and 30.degree. C. to a di-alkali metal salt of 4-bromo-1,8-naphthalic acid and cyclizing to produce 4-bromo-1,8-naphthalic acid anhydride. This novel direct bromination method produces the desired product in good yields and high purity. 4-Bromo-1,8-naphthalic acid anhydride is a valuable intermediate for the preparation of dyestuffs, pigments and optical brighteners.

Abstract: 3-[2-(Phenyloxycycloazalkyl)ethyl]indoles possessing antihypertensive, analgesic, and tranquilizing properties and process for their preparation are described.

Abstract: Novel 1,3-dihydro-heteroarylspiro[isobenzofuran]s and methods of preparing same are described. These compounds are useful as antidepressants and tranquilizers.

Abstract: Novel aminoalkylpyrrolobenzoxazalkanes, physiologically tolerable acid addition salts thereof, method of preparing same and novel intermediates in the preparation thereof are described. These compounds are useful as analgesic agents and tranquilizers.

Abstract: Oxothienobenzoxepin-acetic acids, esters thereof, novel precursors thereof, pharmaceutically acceptable salts thereof and process for their preparation are disclosed. These compounds are useful as antiinflammatory and analgesic agents.

Abstract: Novel 3-anilino-2,4-diazabicyclo[3.2.1]octenes, physiologically tolerable acid addition salts thereof and method of preparing same are described. These compounds are useful as tranquilizers, diuretics and antihypertensives.

Abstract: 1-[1-(Indol-3-ylethyl)-piperazin-4-yl]-3-substituted urea compounds, their physiologically tolerable acid addition salts, and a process for the preparation thereof are described. The compounds are useful as antihypertensive agents.

Abstract: Novel 1,3-dihydrospiro[isobenzofuran-1,4'-piperidine]s and methods of preparing the same are disclosed. These compounds are useful as analgetic, anticonvulsant and antidepressant agents.

Abstract: Novel phenylsulfenylpiperazines and a method of preparing the same are disclosed. These compounds are useful as antihypertensive agents.

Abstract: A method of controlling developer activity in the processing of photosensitized printing plates; comprising, exposing a photographic test film, comprising, a film adapted to pass substantial amounts of light through some portions thereof and substantially lesser amounts of light through other portions thereof, preferably transparent portions and opaque portions, and having a background area and a plurality of insets separated from one another and surrounded by and separated by the background area, the background area having a plurality of regularly spaced dots, having a relatively small total dot perimeter per unit area and a constant dot size and adapted to pass substantial amounts of light through said dots, separated by lines adapted to transmit substantially lesser amounts of light through said lines, each of the insets having a plurality of regularly spaced dots, having a larger total dot perimeter than the small dot perimeter and constant dot size and adapted to pass small amounts of light through said

Abstract: Substituted N-aminoalkylpyrroles of the formula: ##STR1## IN WHICH X, Z, R.sub.1, -R.sub.5 and n are as defined below, and their physiologically tolerable acid addition salts are disclosed to have antiarrhythmic, central nervous system depressant, antiinflammatory and antihypertensive activity. A process for their preparation is also disclosed.

Abstract: New 3-(4-acylaminopiperazin-1-ylalkyl)indole compounds, and their immediate precursors possessing antihypertensive and tranquilizing properties, their physiologically acceptable salts and a process for the preparation thereof are described; said compounds are of the general formula: ##STR1## wherein X represents hydrogen or hydroxy, n can vary from 0-1, R.sub.1 and R.sub.2 each represents hydrogen or alkoxy of 1-2 carbon atoms; R.sub.3 represents hydrogen or alkyl of 1-3 carbon atoms and Z represents hydrogen or ##STR2## and R.sub.4 is selected from a member of the group consisting of alkyl of 1-4 carbon atoms, benzhydryl, cycloalkyl of 6-10 carbon atoms; bridged cycloalkyl of 6-10 carbon atoms, phenyl, mono, di or tri substituted phenyl, and heterocyclic moieties such as pyridyl, furyl, pyrrolyl, thienyl, pyrazinyl.

Abstract: Novel 1,3-dihydro-1'-dimethylphosphinylalkyl-3-phenylspiro[isobenzofuran]s and methods of preparing the same are described. These compounds are useful as antidepressants.

Abstract: Apparatus for developing a printing plate, preferably a plate sensitized and imaged on both sides, including a pre-soak chamber containing a body of developer fluid, preferably a combination developer-finisher solution, and adapted to soften the areas of the plate coating to be removed as the plate passes through the chamber; a cleaning and scrubbing unit, including, a pair of rotatable brushes adapted to rotate in a direction opposite the direction that the plate travels through the apparatus, a pair of developer supply conduits mounted adjacent the brushes and behind the brushes, with respect to the direction of travel of the plate, and adapted to spray developer fluid on the bristles of the brushes at a time immediately before the latter contact the plate, a pair of deflectors mounted in contact with the brushes and ahead of the brushes, with respect to the direction of travel of the plate, and adapted to clean solid debris from the brushes and a pair of reciprocatable scrubber pads having a velour pad and