Abstract: An apparatus to treat a patient comprises a laser beam, a measurement module, a scanner and a curved patient interface lens. The curved patient interface is measured with a pattern so as to determine a plurality of distances of the curved surface at a plurality of measurement locations. The measurement pattern may comprise the plurality of measurement locations distributed about a central measurement axis corresponding to the laser treatment axis. The plurality of measurement locations of the curved surface may correspond to a portion of a planned treatment profile, such that the measured distances correspond to alignment of the planned treatment. The plurality of distances can be used to determine an apex of the curved surface of the patient interface and to align the laser treatment axis with the apex of the curved surface.

Abstract: Methods, software, and systems are provided for determining an ablation target shape for a treatment for an eye of a patient. Techniques include determining wavefront information from the eye of the patient with a wavefront eye refractometer, determining anterior corneal shape information from the eye with a corneal topography device, and combining the wavefront information and the anterior corneal shape information to determine the ablation target shape.

Abstract: Systems, methods, and computer program products are provided for the administration of ablation profiles during refractive surgery treatments. Basis data framework techniques enable the implementation of ablation profiles having various shapes, resulting in increased ablation efficiency when treating certain vision conditions. Exemplary basis data architecture approaches are configured to efficiently operate with annular, elliptical, and slit laser beam shapes, for example, and to account for position-dependent ablation features.

Abstract: A scanning lens component includes a primary and transverse axis stages and motors. The primary axis motor includes a first coil moving along the primary axis in the first direction along with the primary axis stage and a first magnet configured to move in a second, opposite direction, in response to movement of the first coil a first distance that exceeds a threshold primary axis distance. The transverse axis stage is adjacent and coupled to the primary axis stage and moves along a transverse axis in a third direction. The transverse axis motor includes a second coil for moving along the transverse axis in the third direction with the transverse axis stage, and a second magnet configured to move in a fourth, opposite direction, in response to movement of the second coil along the transverse axis in the third direction a second distance that exceeds a threshold transverse axis distance.

Abstract: Deconvolution systems and methods based on cornea smoothing can be used to obtain an ablation target or treatment shape that does not induce significant high-order aberrations such as spherical aberration. Exemplary ablation targets or treatment shapes can provide a post-operative spherical aberration that is equal to or below a naturally occurring amount of spherical aberration.

Abstract: Treatment table verification techniques involve comparing intended refraction information with expected optical refraction information, and validating or qualifying the treatment table based on such comparisons. Systems and methods for verifying treatment tables provide enhanced safety for laser vision correction treatments.

Abstract: System and method of intrastromal refractive correction. The system includes a laser source operable to produce a pulsed beam, a scanner operable to direct the pulsed beam at the eye, and a controller coupled to the laser source and the scanner. The controller determines an intrastromal incision pattern based on a refractive condition of an eye, and directs the scanner to intrastromally incise the pattern in an applanated cornea with the pulsed beam. Following de-applanation, the cornea is reshaped in response to the intrastromal incision pattern to correct the refractive condition.

Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.

Abstract: A system for interfacing a surgical laser with an eye includes a first sensing element to couple to an output surface of the laser, an interface lens having second sensing element coupled to a first surface of the interface lens, and a detector coupled to the first sensing element. A second surface of the interface lens contacts the eye. The detector determines when the first sensing element contacts the second sensing element. A method for aligning the laser with the eye includes coupling the laser to the patient interface, sensing an electrical change indicating a position of the output surface with the interface lens, comparing the electrical change with a predetermined value to produce a correction, and re-positioning the laser with the correction.

Abstract: Methods, software, and systems are provided for determining an ablation target shape for a treatment for an eye of a patient. Techniques include determining wavefront information from the eye of the patient with a wavefront eye refractometer, determining anterior corneal shape information from the eye with a corneal topography device, and combining the wavefront information and the anterior corneal shape information to determine the ablation target shape.

Abstract: An ophthalmic patient interface system includes an interface device and an ocular device. The interface device includes a frame having a first end and a second end, a lens disposed at the first end, and a skirt affixed to the first end. The second end is adapted to couple with a surgical laser system, and the skirt is adapted to seal against an anterior surface of an eye. The ocular device includes magnifying optics and is adapted to be removably seated within the second end. The magnifying optics image a region on a corneal side of the lens when the ocular device is seated within the second end.

Abstract: Systems and methods for fine-tuning refractive shapes for vision treatment are provided. Techniques encompass determining a variable index of refraction for a cornea of the eye, and determining the refractive treatment shape for the eye based on the variable index of refraction. Techniques also encompass determining a variable radius of curvature of an anterior surface of a cornea of the eye, and determining the refractive treatment shape for the eye based on the variable radius of curvature.

Abstract: Systems, methods, computer program products, and kits involving deformation mechanisms are provided for the removal of corneal tissue in optical vision treatments. According to exemplary embodiments, deformation mechanisms may be used in combination with the administration of femtosecond photoalteration lasers to create or define volumetric tissue portions for such removal.

Abstract: Systems and methods related to corneal ablation for treatment of one or more high-order optical aberrations are provided. A method includes providing a defect-correcting prescription, determining an ablation profile to impose the prescription on the cornea, and determining a sequence of laser-energy ablations to impose the ablation profile on the cornea. The prescription comprises a high-order optical correction. The ablation profile includes a first-segment profile and a second-segment profile. The second-segment profile corresponds to at least one high-order optical correction. The ablation sequence includes applying ablations corresponding to the first-segment profile prior to applying ablations corresponding to the second-segment profile.

Abstract: Systems and methods for measuring a topography of an optical tissue surface of an eye are provided by combining a measured elevation of the surface with a priori information of the surface to provide an estimate of mean and covariance of post-measurement orthogonal polynomial sequence amplitudes associated with the surface, determining a variance of elevation of the surface from the estimate, and constructing the topography from the estimate of mean and covariance of post-measurement amplitudes based on a comparison of the variance of elevation of the surface with a pre-determined threshold. The a priori information includes an estimate of mean and covariance of pre-measurement orthogonal polynomial sequence amplitudes associated with the surface.

Abstract: Wavefront measurements of eyes are typically taken when the pupil is in a first configuration in an evaluation context. The results can be represented by a set of basis function coefficients. Prescriptive treatments are often applied in a treatment context, which is different from the evaluation context. Hence, the patient pupil can be in a different, second configuration, during treatment. Systems and methods are provided for determining a transformed set of basis function coefficients, based on a difference between the first and second configurations, which can be used to establish the vision treatment.

Abstract: Embodiments of the invention provide methods and systems for analyzing the ophthalmic anatomy of a patient posterior to the cornea. The method may include scanning a focus of a femtosecond laser beam along a path within the patient's eye. A portion of the path may be disposed posterior to the patient's cornea. The method may also include acquiring a first reflectance image and a second reflectance image associated with the focus disposed respectively at a first location of the path and a second location of the path. The method may further include determining the presence or absence of an ophthalmic anatomical feature of the eye based on a comparison between the first reflectance image and the second reflectance image.

Abstract: Wavefront measurements of eyes are often taken when the pupil is in a first configuration in an evaluation context. The results can be represented by a set of basis function coefficients. Prescriptive treatments are often applied in a treatment context, which is different from the evaluation context. Hence, the patient pupil can be in a different, second configuration, during treatment. Systems and methods are provided for determining a transformed set of basis function coefficients, based on a difference between the first and second configurations, which can be used to establish the vision treatment.

Abstract: Systems and methods for measuring a topography of an optical tissue surface of an eye are provided by combining measured elevations of the surface with a priori information of the surface to provide an estimate of mean and covariance of post-measurement orthogonal polynomial sequence amplitudes associated with the surface, determining a variance of elevation of the surface from the estimate, and constructing the topography from the estimate of mean and covariance of post-measurement amplitudes based on a comparison of the variance of elevation of the surface with a pre-determined threshold. The a priori information includes an estimate of mean and covariance of pre-measurement orthogonal polynomial sequence amplitudes associated with the surface.

Abstract: Systems and methods for fine-tuning refractive shapes for vision treatment are provided. Techniques encompass determining a variable index of refraction for a cornea of the eye, and determining the refractive treatment shape for the eye based on the variable index of refraction. Techniques also encompass determining a variable radius of curvature of an anterior surface of a cornea of the eye, and determining the refractive treatment shape for the eye based on the variable radius of curvature.