Abstract: A method of designing a multifocal ophthalmic lens with one base focus and at least one additional focus, capable of reducing aberrations of the eye for at least one of the foci after its implantation, comprising the steps of: (i) characterizing at least one corneal surface as a mathematical model; (ii) calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model; (iii) modelling the multifocal ophthalmic lens such that a wavefront arriving from an optical system comprising said lens and said at least one corneal surface obtains reduced aberrations for at least one of the foci. There is also disclosed a method of selecting a multifocal intraocular lens, a method of designing a multifocal ophthalmic lens based on corneal data from a group of patients, and a multifocal ophthalmic lens.

Abstract: The present invention relates to devices, systems, and methods for optimizing peripheral vision. In particular, methods are disclosed which include utilizing particular characteristics of the retina in optimizing peripheral vision. Additionally, various IOL designs, as well as IOL implantation locations, are disclosed which optimize peripheral vision.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.

Abstract: Systems and methods for providing enhanced image quality across a wide and extended range of foci encompass vision treatment techniques and ophthalmic lenses such as contact lenses and intraocular lenses (IOLs). Exemplary IOL optics can include a circular surface structure with limited adjacent echelettes which act as a diffractive or phase shifting profile.

Abstract: An ophthalmic lens, such as an intraocular lens (IOL), a phakic IOL or a corneal implant, and a system and method relating to same, having coupled thereto one or more rotationally asymmetric and/or non-continuous diffractive zones, such as for providing improved multifocal vision correction.

Abstract: Systems and methods for providing enhanced image quality across a wide and extended range of foci encompass vision treatment techniques and ophthalmic lenses such as contact lenses and intraocular lenses (IOLs). Exemplary IOL optics can include a circular surface structure which acts as a diffractive or phase shifting profile. In some cases, a single ring IOL includes an anterior face and a posterior face, where a profile can be imposed on the anterior or posterior surface or face. The profile can have an inner portion such as a microstructure or central echelette, and an outer portion. Between the inner portion and the outer portion, there may be a transition zone that connects the inner and outer portions.

Abstract: A method of manufacturing an intraocular lens inside a capsular bag after the natural lens has been removed employs a sealing device comprising a plug part adapted to seal a rhexis in a capsular bag, thus preventing displacement through the rhexis of a lens-forming liquid material injected through the rhexis and adapted to replace the natural lens and form an intraocular lens implant. The plug part has a slightly larger area than the capsulorhexis and is made of a deformable polymer. The sealing device comprises an adjusting means connected to the plug part, the adjusting means having the function of positioning the plug part to a desired location.

Abstract: System, ophthalmic lens, and method for extending depth of focus includes an optic having a clear aperture disposed about a central axis. The optic includes a first surface and an opposing second surface. The first and second surfaces are configured to introduce an asymmetric aberration to the eye while maintaining the in-focus visual acuity.

Abstract: The invention relates to method of preparing a viscoelastic therapeutic liquid comprising a viscoelastic agent and a homogenously distributed therapeutically active agent, wherein the therapeutically active agent is distributed throughout the viscoelastic compound when the viscoelastic compound is in dry form. In one embodiment of the invention, the viscoelastic compound in dry form is mixed with an aqueous solution of the therapeutically active agent. The invention further relates to utilities of homogenous viscoelastic compositions in therapeutic applications including ophthalmic surgery.

Abstract: The present invention relates to devices, systems and methods for determination or selection of a lens power based on the postoperative vitreous length of an eye. The measurement of VLpre is highly predictive in calculating the postoperative vitreous length, from which the position of the implanted intraocular lens or optic can be derived, and then selection of the appropriate lens power.

Abstract: The present invention provides improved ophthalmic lenses and methods for their design and use. Monofocal and multifocal diffractive ophthalmic lenses having reduced light scatter and/or improved light energy distribution properties are provided. These properties are provided by the diffractive profiles of the invention, often having subtly shaped echelettes with appropriately curving profiles. Light scatter may be generated by the sharp corners associated with vertical steps between adjacent conventional diffractive echelettes. Smooth diffractive profiles of the invention reduce light scatter. Light energy directed towards non-viewing diffractive orders may have a unwanted effects on vision quality. Diffractive profiles of the invention may limit the light energy in certain, selected orders, thereby improving viewing quality and mitigating unwanted effects such as dysphotopsia.

Abstract: The present invention provides improved ophthalmic lenses and methods for their design and use. Monofocal and multifocal diffractive ophthalmic lenses having reduced light scatter, improved light energy distribution properties, and/or other improvements in optical performance are provided. These properties are provided, at least in part, by the diffractive profiles of the invention, often having subtlety shaped echelettes with appropriately curving profiles. Smooth diffractive profiles may be used reduce light scatter. Diffractive profiles may be configured to limit the light energy in certain selected orders, thereby improving viewing quality and mitigating unwanted effects such as dysphotopsia. Diffractive profiles of may additionally or alternatively vary the light energy distributed between individual echelettes, providing additional advantages in various viewing situations.

Abstract: A sealing device for use inside a capsular bag after the natural lens has been removed comprises a plug part adapted to seal a rhexis in a capsular bag, thus preventing displacement through the rhexis of a lens-forming liquid material injected through the rhexis and adapted to replace the natural lens and form an intraocular lens implant. The plug part has a slightly larger area than the capsulorhexis and is made of a deformable polymer. The sealing device further comprises a removable adjusting means connected to the plug part, the adjusting means protruding anteriorly from an outer surface of the plug part and being capable of positioning the plug part to a desired location.

Abstract: The present invention relates to devices, systems and methods for determination or selection of a lens power based on the postoperative vitreous length of an eye. The combined measurements of VLpre, ACDpre, AL, and/or LT are highly predictive in calculating the postoperative vitreous length, from which the position of the implanted intraocular lens or optic can be derived, and then selection of the appropriate lens power.

Abstract: An intraocular lens for providing a subject with vision at various distances includes an optic having a first surface with a first shape, an opposing second surface with a second shape, a multifocal refractive profile, and one or more diffractive portions. The optic may include at least one multifocal diffractive profile. In some embodiments, multifocal diffractive and the multifocal refractive profiles are disposed on different, distinct, or non-overlapping portions or apertures of the optic. Alternatively, portions of the multifocal diffractive profiles and the multifocal refractive profiles may overlap within a common aperture or zone of the optic.

Abstract: The present invention provides improved ophthalmic lenses and methods for their design and use. Monofocal and multifocal diffractive ophthalmic lenses having reduced light scatter, improved light energy distribution properties, and/or other improvements in optical performance are provided. These properties are provided, at least in part, by the diffractive profiles of the invention, often having subtlety shaped echelettes with appropriately curving profiles. Smooth diffractive profiles may be used reduce light scatter. Diffractive profiles may be configured to limit the light energy in certain selected orders, thereby improving viewing quality and mitigating unwanted effects such as dysphotopsia. Diffractive profiles of may additionally or alternatively vary the light energy distributed between individual echelettes, providing additional advantages in various viewing situations.

Abstract: The invention relates to devices and methods for selecting IOLs for implantation and eye models useful with the methods. One method comprises the steps of determining the axial eye length, the pupil size at a desired light level; the desired postoperative refraction; determining an aspheric representation of the corneal curvature and determining the location of the plane of fixation of the IOL following implantation.

Abstract: An intraocular lens, and a system and method of providing an intraocular lens, having at least one characteristic of the intraocular lens customized in accordance with a modified regression that includes a modification for corneal spherical aberration. The lens, system and method may indicate measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration of the eye, applying at least one empirically derived regression calculation, and predictively estimating, in accordance with an output of the at least one empirically derived regression calculation, the at least one characteristic of the intraocular lens to obtain the desired postoperative condition.

Abstract: An apparatus, system and method including an ophthalmic lens having an optic with an anterior surface, a posterior surface, and an optical axis. The ophthalmic lens further includes a first region having a first optical power and a second region having a second optical power. The ophthalmic lens further includes a third region having an optical power that progresses from the first optical power to the second optical power. The progression may be uniform or non-uniform. Each of the first, second and progression optical power may include a base power and an optical add power. Each of the first, second and progression regions may provide a first focus, a second focus and a plurality of third foci, respectively.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.