Abstract: A novel senotherapy peptide and a method for senotherapy are disclosed. The method for sentherapy includes administering an effective amount thereof to a subject in need thereof. The novel senotherapy peptide suppresses the interaction between p53 and FOXO4 in the nucleus due to a better binding force with p53 than FOXO4, thereby allowing p53 to be released out of the nucleus and move to mitochondria to induce apoptosis of senescent cells and selectively induce the apoptosis of senescent cells in the skin cells.

Abstract: The present disclosure relates to a smart mirror, a controlling method thereof, and a system for purchasing a cosmetic. According to an aspect of the present disclosure, a smart mirror comprising: a terminal unit including a sensor capable of recognizing a user; a lighting unit including an LED capable of irradiating light to the user; and a control module capable of controlling at least one of the amount of light and the color temperature of the light irradiated from the lighting unit so that the skin of the user represents the light amount and the color temperature in a preset range by the light irradiated from the lighting unit may be provided.

Abstract: A composition including APsulloc 331261 (accession number: KCCM11179P) strain of Lactobacillus plantarum, a lysed product thereof, a culture thereof, an extract thereof, or mixtures thereof is disclosed. The composition has an activity of improving or treating disorders of the digestive system caused by alcohol or inflammation to facilitate the recovery of and improve the welfare of relevant patients. A method of preventing, improving, or treating gastrointestinal disorders by using the composition is disclosed.

Abstract: Disclosed herein is a method for senotherapy; prevention, improvement or treatment of aging-related disease; improvement of skin elasticity or wrinkles; improvement of skin barrier; or improvement of skin pigmentation, containing administering an effective amount of tea tree (Camellia Sinensis) root extract to a subject in need thereof. In one aspect, a senotherapy composition containing the tea tree (Camellia Sinensis) root extract has an excellent senolytic effect to selectively remove senescent cells and an excellent senomorphic effect to inhibit the production of senescence associated secretory phenotype (SASP) of senescent cells.

Abstract: An applicator for applying a patch to the skin is disclosed. A representative exemplary applicator for attaching a patch to the skin has the advantage that a patch can be easily removed and easily and effectively attached to the skin, by including a supporting unit and a patch-attaching unit. The supporting unit can elastically deform in one direction and then restores in the other direction, and the patch-attaching unit, supported by the supporting unit, has a first adhesive surface formed on one side for temporarily adhering a patch.

Abstract: Embodiments relate to a skin diagnosis system and method based on image analysis using deep learning, containing: a face recognition model that derives shape or location information of a facial structure by recognizing feature points capable of identifying an individual in an acquired face image; a de-identification model that de-identifies a face image on the basis of the shape or location information of the facial structure such that personal information of an analysis target cannot be identified; and a plurality of artificial neural network models for each of at least one item among diagnoses for wrinkles, pigmentation, pores, erythema, and aging.

Abstract: Disclosed is to provide a composition for skin-whitening or preventing or improving skin wrinkles, comprising a green tea extract which has modified amounts of ingredients. More specifically, the extract and composition according to one aspect of the present disclosure are derived from natural plants that cause less irritation to the skin and are eco-friendly, thus they are safe, and thereby the extract and composition can exhibit excellent effects of effectively inhibiting melanin production and tyrosinase activity and preventing or improving skin whitening, and can exhibit excellent effects of effectively inhibiting the expression of MMP-1 and preventing or improving skin wrinkles.

Abstract: Disclosed herein is a method for inhibiting lipogenesis; inhibiting fat accumulation; promoting fat breakdown; reducing body fat; and/or preventing, improving or treating obesity or metabolic diseases. In one aspect, Gallocatechin Gallate (GCG) and Isoquercitrin (IQC) of the present invention have excellent lipid metabolism control effects, can increase mitochondria in adipocytes, and promote the production of brown fat. Therefore, in one aspect, the present invention can provide a method for preventing, improving, or treating obesity or metabolic diseases.

Abstract: In one aspect, the present disclosure provides a complex containing kojyl methylenedioxycinnamate; a compound containing an ethylene glycol moiety or a propylene glycol moiety; a surfactant containing a saccharide moiety; and an antioxidant, and an emulsion formulation containing the complex. In another aspect, the present disclosure provides a method for manufacturing the complex, comprising: (a) adding kojyl methylenedioxycinnamate, a compound containing an ethylene glycol moiety or a propylene glycol moiety, a surfactant containing a saccharide moiety, and an antioxidant; and (b) homomixing the result of the (a).

Abstract: According to an aspect of this disclosure, there is provided a fluid processing apparatus including: a housing with a space formed therein; a fluid receiving part removably coupled to the housing and receiving a fluid therein; and a conveying part accommodated in the space of the housing and coupled to the fluid receiving part to be in fluid communication therewith, wherein the conveying part includes: a pump member coupled to the fluid receiving part and providing a conveying force to the fluid; and a mixing nozzle which is in communication with the pump member, and into which the fluid flows after having passed through the pump member.

Abstract: The present disclosure is directed to providing a moldable solid washing agent composition and an article molded from the same. The composition of the present disclosure can be stored easily at room temperature for a long time. It is applicable to a system that can be manufactured on site and can satisfy customer needs because it can be molded immediately by a simple method and the shape, size, etc. can be controlled. In addition, the solid washing agent composition disclosed in the present specification has superior compatibility with water.

Abstract: The present specification describes a method for manufacturing porous inorganic particles and a light-reflecting composition comprising porous inorganic particles. According to an embodiment of the present disclosure it is possible to provide a method for manufacturing porous inorganic particles capable of selective transmission or scattering of light having a specific wavelength range by controlling pore size and shell thickness.

Abstract: The present disclosure relates to a method for lowering blood sugar including administering an effective amount of a green tea peptide composition to a subject in need thereof, and specifically, the green tea peptide composition according to the present disclosure exhibits a blood sugar-lowering effect through excellent stimulation of glucose transport in adipocytes, inhibition of gluconeogenesis in hepatocytes, and DPP-4 inhibitory activity, and can be applied to various health functional food compositions and pharmaceutical compositions.

Abstract: A cosmetic composition containing a multiple emulsion formulation is provided. The multiple emulsion formulation contains droplets including an inner phase and an outer phase and an outermost phase, and an outermost phase. The inner phase may be an oil phase and the outer phase may be an aqueous phase, and the outermost phase includes silicon-based oil. The cosmetic composition may provide excellent formulation stability due to the distribution of the droplets very close to the outermost phase.

Abstract: Provided are a reelin and/or VEGF-C production and/or activation promoter including a compound represented by Chemical Formula 1 and/or a ginseng extract containing the compound, as an active ingredient, and a skin external composition including the same. In Chemical Formula 1, each substituent is as defined in the specification.

Abstract: A composition contains, as an effective component, theasinensin A, an enantiomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a solvate thereof. The composition has an excellent stability and provides wrinkle-reducing or skin elasticity-enhancing benefits, and skin-brightening benefits by containing theasinensin A, an enantiomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a solvate thereof, as an effective component.

Abstract: The present disclosure relates to a composition for preventing gray hair, promoting black hair and preventing, improving or treating vitiligo or hypochromatism, which contains fructose 1,6-bisphosphate or a salt, a solvate, a stereoisomer or a hydrate thereof as an active ingredient, and has been contrived to solve the problem of the prior art that appreciable effect cannot be achieved due to insignificant effect on melanin production. The composition of the present disclosure, which contains fructose 1,6-bisphosphate or a salt, a solvate, a stereoisomer or a hydrate thereof, provides superior effect of preventing gray hair, promoting black hair and treating vitiligo or hypochromatism.

Abstract: A water-in-silicone cosmetic composition is disclosed. The water-in-silicone cosmetic composition contains a water- or silicone-poorly soluble substance. Specifically, the water-in-silicone cosmetic composition can contain a high content of a substance that is poorly soluble in water or silicone by stably dispersing the substance in a silicone phase or aqueous phase, and has excellent long-term stability.

Abstract: The present specification relates to a composition for alleviating skin damage due to hypoxia, which contains one or more selected from the group consisting of a Saccharomyces cerevisiae strain; its lysate; its culture; and an extract of the strain, lysate, or culture as an active ingredient, and a novel Saccharomyces cerevisiae strain, and the composition, which contains one or more selected from the group consisting of a Saccharomyces cerevisiae strain; its lysate; its culture; and an extract of the strain, lysate, or culture as an active ingredient, according to an aspect of the present invention is effective in inhibiting the expression of MMP1 and COX2 overexpressed in skin in a hypoxic environment, and is thus excellently effective in improving skin damaged by exposure to a hypoxic environment for a long period of time or repeatedly or alleviating skin damage due to hypoxia.

Abstract: One aspect of the present disclosure relates to a pharmaceutical composition, containing (R)-N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide as a first ingredient and containing a vinylpyrrolidone-based polymer as a second ingredient. The composition of one aspect of the present disclosure has a formulation characteristic in which the crystal formation of a compound represented by chemical formula 1 is delayed for a long time.