Abstract: One aspect of the present disclosure is a pharmaceutical composition which includes (R)—N-[1-(3,5-difluoro-4-methansulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide as a first component and a cellulosic polymer as a second component, wherein the composition of one aspect of the present disclosure has a formulation characteristic in which crystal formation is delayed for a long time.

Abstract: The present disclosure relates to a nanoemulsion composition of oxygen gas sustained release and method for preparing the same, and provides a nanoemulsion composition of oxygen gas sustained release and method for preparing the same, including a water phase part containing water, and an oil phase part dispersed in the water phase part and made of nanoparticle containing a perfluorocarbon compound, wherein the oil phase part contains oxygen gas, and the oxygen gas is released in sustained release. According to the present disclosure, there are advantages of preventing hair loss or promoting hair growth by increasing the amount of oxygen gas supplied to the hair bulb and the oxygen release time from the hair bulb.

Abstract: Disclosed in this specification is a composition comprising polymer hyaluronic acid nanoparticles. In the present disclosure, the polymer hyaluronic acid is micronized to facilitate skin penetration without depolymerization of the polymer hyaluronic acid, and may be stably comprised in a formulation. In addition, the micronized polymer hyaluronic acid comprised in the composition of the present disclosure penetrates the skin and then is neutralized to pH of the skin and expanded in size again, which can provide excellent benefits for moisturizing the skin and improving skin elasticity.

Abstract: An aspect of the present disclosure relates to a composition for improving respiratory health exposed to particulate matter, which contains a green tea extract, a green tea polysaccharide and a green tea flavonol as active ingredients. The composition provided in an aspect of the present disclosure can improve respiratory health damaged by exposure to particulate matter by enhancing the effect of preventing adsorption of particulate matter to bronchial epithelial cells and activating the cilia of bronchial epithelial cells. The composition provided in an aspect of the present disclosure may decrease blood heavy metal level.

Abstract: Disclosed are an oil-dispersed composition and a cosmetic for lip care manufactured using the same. The oil-dispersed composition includes a water-soluble raw material, an ester oil including a glyceryl group and/or an isostearyl group, a paste, and a thickener, wherein the paste and thickener are included in an amount of greater than or equal to about 30 wt % based on the total amount of the oil-dispersed composition.

Abstract: Disclosed is to provide a composition for skin-whitening or preventing or improving skin wrinkles, comprising a green tea extract which has modified amounts of ingredients. More specifically, the extract and composition according to one aspect of the present disclosure are derived from natural plants that cause less irritation to the skin and are eco-friendly, thus they are safe, and thereby the extract and composition can exhibit excellent effects of effectively inhibiting melanin production and tyrosinase activity and preventing or improving skin whitening, and can exhibit excellent effects of effectively inhibiting the expression of MMP-1 and preventing or improving skin wrinkles.

Abstract: The present disclosure provides a composition for promoting hair growth including camellia kaempferol glycoside as an active ingredient. The composition for promoting hair growth according to an aspect of the present disclosure can promote hair growth by promoting the proliferation of hair follicle cells without side effects. In addition, the composition for promoting hair growth can promote hair growth and prevent hair loss by inhibiting the apoptosis of outer root sheath cells. Such a composition for promoting hair growth can be used as an external application to the skin, and can be used as a food, cosmetics or pharmaceutical composition.

Abstract: Disclosed are a method for extracting a compound represented by Chemical Formula 1 from ginseng, including anaerobic natural fermentation of ginseng, an anaerobic-naturally fermented ginseng extract including the compound represented by Chemical Formula 1 extracted by the method, and a method of enhancing the skin barrier including applying a composition including an effective amount of the anaerobic-naturally fermented ginseng extract. In Chemical Formula 1, each substituent is as defined in the specification.

Abstract: A stick-type product having a heating function is disclosed. According to one aspect of the present disclosure, there is provided the stick-type product that includes a handle part that is graspable by a user; a brush rod extending from the handle part; and an application part provided at one end of the brush rod and configured to apply a cosmetic article. The application part has portions of different temperatures by being provided with materials which are capable of heat generation and which have different thermal conductivities.

Abstract: A tip applicator is provided. The tip applicator according to one embodiment captures and applies a cosmetic on skin, and includes an application portion including an application surface for capturing and applying the cosmetic on a skin of a user, the application surface being formed in a surface of the application portion; a support portion which is connected to one side of the application portion to support the application portion; and a capture amount control portion which is formed on the application surface and changes a capture amount of the cosmetic captured by the application surface.

Abstract: A cosmetic composition for makeup removal and its use for removing facial make-up are disclosed. The composition includes a water-soluble surfactant and an oil-soluble surfactant and. The composition, more specifically, includes, as an active ingredient, a mixture of a water-soluble surfactant having a hydrophile-lipophile balance (HLB) value of 13 or more and an oil-soluble surfactant having an HLB value of 12 or less. The composition can excellently remove makeup residues resulting from using a makeup product, can excellently improve the transparency of the composition, and is excellent in feeling of use on the skin.

Abstract: The present invention relates to a core-shell network structure formed using a biocompatible biopolymer and to a composition comprising same. Said structure can be used as an alternative to synthetic chemical materials, such as polyethylene glycol (PEG), to effectively disperse an insoluble effective substance within a composition, thus addressing safety issues, and formulations can be preserved stably for a long time through said network structure. Furthermore, said structure and the composition comprising same may provide useful benefits for the skin in terms of skin barrier enhancement, skin moisturization, skin regeneration, or the like.

Abstract: Disclosed in the present specification is a liquid lipid composite composition comprising ceramide, cholesterol, a C10-30 unsaturated fatty acid having three or fewer double bonds, and natural oil or wax containing a C10-60 fatty acid ester or C10-60 fatty acid ester at a weight ratio of 1:0.03-3:2.5-12:0.3-6. The liquid lipid composite composition comprises a high content of ceramide and is present in a liquid state during storage at normal temperature, and thus can be easily applied as a formulation of a hair cosmetic composition. The liquid lipid composite composition, when used to treat hair, has excellent hair condition improving effects, such as improving the softness of the hair, enhancing the elasticity and strength of the hair, and increasing the shininess of the hair.

Abstract: Disclosed is to provide a composition for skin-whitening or preventing or improving skin wrinkles, comprising a green tea extract which has modified amounts of ingredients. More specifically, the extract and composition according to one aspect of the present disclosure are derived from natural plants that cause less irritation to the skin and are eco-friendly, thus they are safe, and thereby the extract and composition can exhibit excellent effects of effectively inhibiting melanin production and tyrosinase activity and preventing or improving skin whitening, and can exhibit excellent effects of effectively inhibiting the expression of MMP-1 and preventing or improving skin wrinkles.

Abstract: A container for dispensing solid contents is disclosed. The container includes: a housing configured to store a plurality of solid contents having a predetermined shape; a dispensing member having a dispensing opening from which the solid contents are dispensed; and a rotating member provided on the upper side of the dispensing member to allow relative rotation with the dispensing member and configured to move at least some of the plurality of solid contents to the dispensing opening.

Abstract: Disclosed is a method for preventing or treating atopic dermatitis using TRPV1 receptor antagonist. More specifically, it may be possible to prevent and/or treat the atopic dermatitis without any side effects such as an increase in body temperature, epidermal atrophy, and the like by percutaneously administrating a composition for external use on the skin containing the TRPV1 receptor antagonist.

Abstract: This disclosure relates to a refillable cosmetic container. According to an aspect of the disclosure, a refillable cosmetic container can be provided, which includes a refill container configured to store a content, and a container body selectively coupled with the refill container, wherein in the refill container, a fixing groove is formed, and wherein in the container body, an elastic part is formed, which is provided to be elastically deformable by an external force applied by the refill container, and which is configured to be fixed in the fixing groove via the relative rotation between the refill container and the container body.

Abstract: A cosmetic container including an impregnation member having the surface intaglio-patterned by laser beam machining is provided. The surface of the impregnation member is heated and burned by a laser to form an intaglio-pattern, and an intaglio-pattern part having the intaglio-pattern is formed with a width of 0.1 mm to 5.0 mm so that the intaglio-pattern part formed by the laser is maintained in the open cell structure and has the large discharge surface area, so a user easily adjusts an amount of discharged cosmetic material according to force applied to the impregnation member and use the cosmetic material. The cosmetic container includes an outer container having an open upper portion, an outer container lid coupled to the outer container, an inner container mounted inside the outer container, the impregnation member in the inner container and impregnated with cosmetic material and an inner container lid hinged with the inner container.

Abstract: A method for reducing absorption of a microplastic in a body, including administering a composition including an effective amount of a green tea extract to a subject in need thereof is disclosed in the specification. One aspect of the present disclosure is the composition may be a food composition or a pharmaceutical composition.

Abstract: The present disclosure relates to a method for preparing hyaluronic acid nanoparticle and to hyaluronic acid nanoparticle prepared by the method. In one aspect of the present disclosure, the method for preparing hyaluronic acid nanoparticle can minimize the size of the hyaluronic acid nanoparticle, and the hyaluronic acid nanoparticle prepared by the method has low viscosity characteristics and is excellent in spreadability, and can penetrate the stratum corneum evenly when applied to the skin.