Abstract: Among other things, one or more techniques and/or systems are described for defining imaging modes and for operating a photon counting radiation imaging system. A set of imaging modes with different counting schemes may be defined such that counting schemes will count detection events of a set of radiation events in different manners. For example, a first counting scheme may count primary detection events in a primary counter and secondary detection events in a secondary counter. A second counting scheme may count primary and secondary detection events in the primary counter. A third counting scheme may merely count detection events occurring within a primary detector cell associated with the primary counter. A fourth counting scheme may combine energy of detection events into merged energy. A selected imaging mode may be applied to the photon counting radiation imaging system in order to achieve desired image scanning characteristics (e.g., spatial resolution, dose savings, spectral ability).

Abstract: A subject target tissue specific template device (300) that includes a block of material (302) and a plurality of apertures (310) in the material. An aperture of the plurality of apertures is located in the block of material at a location that corresponds to an area of interest identified in an image of an anatomical region of interest of a subject and transferred to an image of block of material with no aperture, which is geometrically aligned with the image of the anatomical region of interest of the subject. A method includes aligning, with a computing system, an image of anatomical tissue of interest with an image of a grid, marking at least one area of interest of tissue of interest within the image of tissue of interest, transferring the marking to the image of the grid, and saving the image of a grid with the marking as a file in an electronic format.

Abstract: A multi-zone digital-to-analog device is provided with a digital-to-analog (D/A) stage having an input to accept a digital input signal with a data bandwidth of M Hertz (Hz), a clock input to accept a clock signal with a clock frequency of P Hz, and an output to supply an analog value having a bandwidth of M Hz. An upsampling stage has an input to accept the analog value and a clock input to accept the clock signal. The upsampling stage has a device bandwidth of L Hz to supply an analog output signal with a full power bandwidth of K Hz, where (P/2)=M and M<K<L. The upsampling stage supplies analog output signal images in a plurality of Nyquist zones. In one aspect, the D/A stage supplies N deinterleaved analog values having a combined bandwidth of M Hz, where N×(P/2)=M.

Abstract: A method includes obtaining first 3D imaging data for a volume of interest. The first 3D imaging data includes structural imaging data and a target tissue of interest. The method further includes obtaining 2D imaging data. The 2D imaging data includes structural imaging data for a plane of the volume of interest. The plane includes at least three fiducial markers of a set of fiducial markers. The method further includes locating a plane, including location and orientation, in the first 3D imaging data that corresponds to the plane of the 2D imaging data by matching the at least three fiducial markers with corresponding fiducial markers identified in the first 3D imaging data and using the map. The method further includes visually displaying the first 3D imaging data with the 2D imaging data superimposed over at the corresponding plane located in the first 3D imaging data.

Abstract: A method for determining an allelic ladder signal for DNA analysis includes obtaining a measured allelic ladder signal for an allelic ladder substance, which includes a plurality of fragments, obtaining a reference set of expected fragment sizes of fragments of the ladder substance, and generating a signal identifying whether a peak for a fragment size of the measured ladder signal is a true peak of the ladder substance based on the reference set of expected fragment sizes, wherein the allelic ladder signal for DNA analysis includes the true peaks identified in the signal.

Abstract: A power delivery system includes a rotary transformer having a primary winding and a secondary winding and configured to transfer power between stationary coupling elements on a stationary side and rotational coupling elements on a rotational side. The rotational coupling elements share a central axis with the stationary coupling elements, and are adapted to rotate with respect to the stationary coupling elements. The power delivery system includes an isolation transformer that drives the primary winding of the rotary transformer, and a plurality of power inverter stages whose outputs are adapted to be summed and coupled to the rotary transformer. A plurality of output power converters receive transmitted power from the rotary transformer. A plurality of control elements, disposed on the rotating side, are configured to close a feedback loop on desired and actual performance of the output power converters, and to control the power inverter stages.

Abstract: Among other things, one or more techniques and/or systems are described herein for transferring communication information between a stationary unit and a movable (e.g., rotating) unit, or between two movable units without contact between the units. A transmitter is configured to translate digital information into an analog signal which may be fed to an input coupler positioned within a channel of an electrically conductive member (e.g., on a first unit, such as a stationary unit). The current of the signal induces a signal in an output coupler (e.g., on a second unit, such as a movable unit). Voltage characteristics of the induced signal (e.g., which substantially correspond to voltage characteristics of the signal fed into the input coupler) may subsequently be used to reconstruct the digital data at a receiver. In this manner, information can be communicated between two non-contacting units.

Abstract: Among other things, one or more techniques and/or systems are described for presenting images derived from a photon counting imaging modality. Initially, a first image is derived by binning native projection data in a first manner to create first binned data and generating the first image using the first binned data. A region-of-interest within the object may be identified from the first image, and, based upon the identified region-of-interest, the native projection data may be rebinned in a second, different, manner to create second binned data. Because the second manner of binning the native projection data is different than the first manner, an image resulting from the second binned data may be different than the first image. Moreover, a user interface may be provided for assisting a user in selecting a region-of-interest and/or for specifying desired properties of the second image.

Abstract: A method includes generating a real-time ultrasound image of anatomy of interest. At least a sub-portion of the anatomy of interest is deformed from an initial location to a different location by pressure applied by an external force. The method further includes obtaining a 2-D slice, which corresponds to a same plane as the real-time ultrasound image, from 3-D reference image data, wherein a corresponding sub-portion is at the initial location. The method further includes determining displacement fields for the sub-portion from the sub-portion, the corresponding sub-portion and other anatomy not-deformed in the real-time ultrasound image and the 3-D reference image data. The method further includes deforming the 3-D reference image data using the displacement fields, which creates deformed 3-D reference image data based on the different location.

Abstract: A sample processing apparatus (102) includes a plurality of processing stations (108) configured to process a sample that includes a DNA sample and an ILS substance carried by a sample carrier. One of the plurality of processing stations includes an electrophoresis processing station. The sample processing apparatus further includes an optical reader (110) that generates a plurality of DNA sample color group signals and an ILS signal based on a result of the electrophoresis processing station. One of the DNA sample color group signals includes at least the locus amelogenin X-peak. The sample processing apparatus further includes an ILS signal validator (112) that validates peaks of the ILS signal as true peaks of the ILS signal only if the amelogenin X-peak of the one of the DNA sample color group signals is found between two peaks of the ILS signal.

Abstract: Systems, apparatus and methods for localizing and/or determining the relative position of surgical instruments during a surgical procedure are disclosed. A method includes capturing an image depicting at least a portion of a first surgical instrument disposed at a first position with respect to a target tissue, and at least a portion of a second surgical instrument disposed at a second position with respect to the target tissue, the second position different from the first position. The method includes transforming the image to a three-dimensional model so the first position of the portion of the first surgical instrument is rendered with the three-dimensional model, and the second position of the portion of the second surgical instrument is rendered with the three-dimensional model. The method includes calculating distance between the portion of the first surgical instrument and the portion of the second surgical instrument based on the three dimensional model.

Abstract: A CT scanning system may include a multi-pixel x-ray source, and a detector array. The multi-pixel x-ray source may have a plurality of pixels that are disposed along a z-axis, and that are sequentially activated so as to controllably emit x-rays in response to incident electrons. The detector array may have one or more rows of x-ray detectors that detect the x-rays that are emitted from the pixels and have traversed an object, and generate data for CT image reconstruction system. In third generation CT scanning systems, the number of detector rows may be reduced. Multi-pixel x-ray source implementation of saddle curve geometry may render a single rotation single organ scan feasible. Using a multi-pixel x-ray source in stationary CT scanning systems may allow x-ray beam design with a minimal coverage to satisfy mathematical requirements for reconstruction.

Abstract: Among other things, an energy shield (212) for a radiation system, such as a security imaging system, is provided. The energy shield is comprised of one or more flaps (300). At least one flap defines an aperture (320) providing a demarcation between a first flap segment (322) of the flap and a second flap segment (324) of the flap. The aperture (e.g., and a flexible member (326) positioned spatially proximate the aperture) provide for (e.g., facilitate) movement of the second flap segment relative to the first flap segment. In this manner, an amount of force required to be applied by an object to pass by the flap may be reduced when the object is small and merely contacts the second flap segment, for example. In this manner, baggage jams may be mitigated, for example, by reducing the likelihood that certain objects will be impeded from passing through the energy shield.

Abstract: Among other things, one or more rotating members of a radiation imaging modality, such as a CT system, are described herein. The rotating member may be configured to support at least one of a radiation source or a detector array and comprises at least one element configured to facilitate the transfer of power to the rotating member and at least one element configured to facilitate the transfer of information between the rotating member and a stator. The rotating member may also comprise one or more positioning elements that are formed within the rotating member and are configured to facilitate determining a rotation angle of the rotating member. The rotating member may further comprise, among other things, a bearing structure, antenna assembly for transferring image data, and/or a drive mechanism for facilitating rotation of the rotating member, for example.

Abstract: Among other things, radiation systems and techniques for generating volumetric data and projections images of an object(s) under examination are provided. The radiation system comprises at least two detector arrays and at least one radiation source. During an examination, the radiation source and at least one detector array are rotated about the object while a second detector array is substantially fixed in place. In one embodiment, the radiation source is configured to, at times, illuminate the first detector array and, at times, illuminate the second detector array. For example, the radiation source may illuminate the first detector array during nearly all of the rotation while the second detector array is merely illuminated at a single gantry rotation angle. Information generated by the second detector array may be utilized to yield volumetric data while information generated by the first detector array may be utilized to yield a projection image, for example.

Abstract: A sample carrier (102) includes a sample support region (104) that supports a sample to be processed by a sample carrier processing apparatus and storage and communications circuitry (106) that includes a wireless interface (502) that wirelessly communicates with a storage component reader of the sample processing apparatus when the sample carrier is loaded in the sample processing apparatus for processing. A sample carrier processing apparatus (100) includes a plurality of sample carrier receiving regions (116) respectively configured to receive individual sample carriers carrying samples to be processed by the sample carrier processing apparatus and a plurality of storage component readers (120), one for each of the plurality of sample carrier receiving regions and respectively configured to wirelessly communicate, one to one, with the sample carrier in a corresponding one of the sample carrier receiving regions.

Abstract: A CT scanner comprises: at least one source of X-rays and a multi-row detector array of arbitrary geometry, both supported so as rotate around an axis of rotation during a scan of an object translated along the axis, wherein data for each detector is generated as a function of the X-ray energy received; and a data processor configured so as to perform resampling of the data onto curves in a virtual detector array. The curves project onto tilted lines in a virtual flat detector as to enable tangential filtering of the data.

Abstract: Among other things, one or more systems and/or techniques for identifying an occlusion region in an image representative of an object subjected to examination is provided for herein. Such systems and/or techniques may find particular application in the context of object recognition analysis. An image is generated of the object and an orientation of the object is determined from the image. Based upon the determined orientation of the object relative to the direction the object is translated during examination, one or more parameters utilized for segmenting a second image of the object, identifying features in the image, and/or determining if the image comprises an occlusion region may be adjusted. In this way, the parameters utilized may be a function of the determined orientation of the object, which may mitigate false positives of detected occlusion regions.

Abstract: Multi-energy imaging is afforded with a single detector array by generating a first data set, indicative of a first radiation energy spectrum, using a first set of cells of the array, and by generating a second data set, indicative of a second radiation energy spectrum, using a second set of cells of the array (e.g., where substantially more cells are in the first set than the second). The first data set is comprised of measured data from the first set of cells and estimated data that would have been yielded from the second set of cells had the second set been configured to detect the first energy spectrum. The second data set is comprised of measured data yielded from the second set of cells and estimated data that would have been yielded from the first set of cells had the first set been configured to detect the second energy spectrum.

Abstract: A method includes calibrating color bleed factors of optical detector channels of a sample processing apparatus through processing a color bleed calibration substance which includes a plurality of different size fragments replicated from different groups of DNA loci, wherein fragments in a same group are labeled with a same fluorescent dye, and fragments in different groups are labeled with different fluorescent dyes having different emission spectra, wherein the different size fragments are processed during different acquisition times.