Abstract: Disclosed herein are intrasacular aneurysm occlusion devices with nested proximal and distal meshes. A proximal mesh covers the aneurysm neck. A flexible distal mesh expands to fill even an irregularly-shaped aneurysm sac when it is expanded by the insertion of embolic members and/or material.

Abstract: This invention can be embodied in a method and device for therapeutically-occluding a cerebral aneurysm. A method embodiment includes radially-constraining a tubular mesh to form proximal and distal convex portions of the mesh, collapsing the proximal portion into a concave (e.g. bowl) shape, and expanding the distal portion of the mesh within an aneurysm sac by filling it with embolic members and/or material. The expanded distal portion of the mesh holds the concave proximal portion securely against the aneurysm neck and conforms to the wall contours of even an irregularly-shaped aneurysm sac.

Abstract: Disclosed herein are intrasacular aneurysm occlusion devices with nested proximal and distal meshes. A proximal mesh covers the aneurysm neck. A flexible distal mesh expands to fill even an irregularly-shaped aneurysm sac when it is expanded by the insertion of embolic members and/or material.

Abstract: Disclosed herein is an intrasacular aneurysm occlusion device with a proximal bowl-shaped mesh which covers the neck of an aneurysm sac and a distal globular mesh between the proximal bowl-shaped mesh and the dome of the aneurysm sac. The proximal bowl-shaped mesh blocks blood flow into the aneurysm sac and the distal globular mesh holds the bowl-shaped mesh in place against the aneurysm neck.

Abstract: This invention is an intrasacular aneurysm occlusion device with a longitudinal mesh ribbon having a series of loops or segments with distal-to-proximal variation in their sizes, shapes, or orientations. For example, loops or segments can be progressively smaller in size and/or progressively more curved as one views the series in a distal-to-proximal direction. The device may also enable a user to selectively and remotely bend, steer, or elongate the loops or segments in real time as the ribbon is being deployed into an aneurysm sac.

Abstract: Disclosed herein is an intrasacular aneurysm occlusion device with a linearly-aligned proximal-to-distal stack of embolic structures which is configured to be inserted into an aneurysm sac and then radially-expanded and longitudinally-contracted. The stack can be shaped like a 3D revolution of three single phases (or one and half full phases) of a sine wave around its central longitudinal axis. There can be openings in the stack which allow insertion of embolic material (e.g. coils, hydrogels, or congealing material) into the embolic structures.

Abstract: This invention is an intrasacular aneurysm occlusion device with nested structures, including an inner embolic structure (e.g. inner mesh, net, braid, and/or stent) which is nested inside an outer embolic structure (e.g. outer mesh, net, braid, and/or stent). The inner embolic structure can have an ellipsoidal, toroidal, inverted jug, or inverted bottle shape. The outer embolic structure can have a spherical shape. The device can also have an opening and valve through which embolic material is inserted into the aneurysm sac.

Abstract: This intrasacular aneurysm occlusion device includes a neck bridge with a closeable opening through which embolic material is inserted into an aneurysm sac. After the neck bridge has been expanded within the aneurysm sac, a catheter is inserted through the opening and embolic material is delivered through the catheter into the aneurysm sac. After the aneurysm sac has been filled with embolic material, the catheter is then withdrawn and the opening is closed so that embolic material does not escape out of the aneurysm sac.

Abstract: Disclosed herein is a method for occluding a cerebral aneurysm which includes: delivering a flexible implant in a compressed first configuration to a cerebral aneurysm through a catheter; inserting the flexible implant into the aneurysm sac wherein the flexible implant self-expands to a second configuration; and then delivering embolic members and/or embolic material into the flexible implant to expand further the flexible implant into a third configuration which conforms to the walls of even an irregularly-shaped aneurysm sac.

Abstract: This invention is an intrasaccular aneurysm occlusion device comprising: a net or mesh with a self-expanding resilient proximal portion (which is deployed close to the aneurysm neck) and an expandable flexible distal portion (which is deployed close to the aneurysm dome); and a “string of pearls” of embolic members which are inserted into the net or mesh.

Abstract: Disclosed herein is a bowl-shaped neck bridge with a distal-facing concavity and a central lumen. The neck bridge is inserted and expanded within a cerebral aneurysm. The, embolic members (such as embolic coils, embolic ribbons, or string-of-pearls embolic strands) are inserted through the central lumen into the aneurysm sac.

Abstract: This invention is an intrasacular aneurysm occluding device with a flexible outer mesh and a resilient inner structure inside the outer mesh, wherein embolic members are inserted between the flexible outer mesh and the resilient inner structure.

Abstract: This invention is an intrasacular aneurysm occlusion device with a proximal stent which is expanded to a globular shape within an aneurysm sac and then compressed into a bowl shape which covers the aneurysm neck. The device further comprises embolic members and/or embolic material which is inserted into a distal portion of the aneurysm sac. The proximal stent component covers the aneurysm neck so as to reduce blood flow into the aneurysm sac and the accumulated embolic members and/or embolic material in the distal portion of the aneurysm sac keeps the proximal stent in place.

Abstract: Disclosed herein is a method for occluding a cerebral aneurysm which includes: delivering a flexible implant in a compressed first configuration to a cerebral aneurysm through a catheter; inserting the flexible implant into the aneurysm sac wherein the flexible implant self-expands to a second configuration; and then delivering embolic members and/or embolic material into the flexible implant to expand further the flexible implant into a third configuration which conforms to the walls of even an irregularly-shaped aneurysm sac.

Abstract: This invention is an intrasacular aneurysm occlusion device with a longitudinal mesh ribbon having a series of loops or segments with distal-to-proximal variation in their sizes, shapes, or orientations. For example, loops or segments can be progressively smaller in size and/or progressively more curved as one views the series in a distal-to-proximal direction. The device may also enable a user to selectively and remotely bend, steer, or elongate the loops or segments in real time as the ribbon is being deployed into an aneurysm sac.

Abstract: This invention is an intrasacular aneurysm occlusion device with an embolic-filled flexible mesh which is formed from a tubular mesh by encircling, pinching, inverting, and/or everting the tubular mesh at one or more longitudinal locations using one or more rings, bands, or cylinders. Embolic material is inserted into the flexible mesh through the rings, bands, or cylinders.

Abstract: This invention is an intrasacular aneurysm occlusion device comprising a flexible net or mesh with a proximal portion and a distal portion which is inserted into and expanded within an aneurysm sac. The proximal portion is stiffer and/or less flexible than the distal portion. The device also includes an opening through which embolic members and/or embolic material is inserted into the flexible net or mesh. Insertion of embolic members and/or material causes the flexible net or mesh to expand and conform to the walls of even an irregularly-shaped aneurysm sac.

Abstract: This invention is an intrasacular aneurysm occlusion device with a proximal stent which is expanded to a globular shape within an aneurysm sac and then compressed into a bowl shape which covers the aneurysm neck. The device further comprises embolic members and/or embolic material which is inserted into a distal portion of the aneurysm sac. The proximal stent component covers the aneurysm neck so as to reduce blood flow into the aneurysm sac and the accumulated embolic members and/or embolic material in the distal portion of the aneurysm sac keeps the proximal stent in place.

Abstract: This invention is an intrasaccular aneurysm occlusion device with a flexible net or mesh which is deployed into an aneurysm sac and then expanded by the insertion of polymer longitudinal embolic members (e.g. polymer tubular strands) into the net or mesh. As the net or mesh expands, it comes into contact with the walls of the aneurysm sac and conforms to the shape of even an irregularly-shaped aneurysm sac.

Abstract: This intrasacular aneurysm occlusion device includes a neck bridge with a closeable opening through which embolic material is inserted into an aneurysm sac. After the neck bridge has been expanded within the aneurysm sac, a catheter is inserted through the opening and embolic material is delivered through the catheter into the aneurysm sac. After the aneurysm sac has been filled with embolic material, the catheter is then withdrawn and the opening is closed so that embolic material does not escape out of the aneurysm sac.