Abstract: An intrasacular aneurysm occlusion device can be a peanut, hourglass, and/or hyperbolic shaped mesh which is inserted and expanded within an aneurysm sac. The proximal lobe of the device reduces blood flow into the sac through the aneurysm neck and the distal lobe of the device contacts the dome of the sac so as to keep the proximal lobe from shifting. The narrow center portion of the peanut, hourglass, or hyperbolic mesh can bend so that the device at least partially conforms to the interior of an irregularly-shaped aneurysm sac.

Abstract: Disclosed herein is a bowl-shaped neck bridge with a distal-facing concavity and a central lumen. The neck bridge is inserted and expanded within a cerebral aneurysm. The, embolic members (such as embolic coils, embolic ribbons, or string-of-pearls embolic strands) are inserted through the central lumen into the aneurysm sac.

Abstract: This invention is a “bowl-of-spaghetti” type intrasacular aneurysm occlusion device including: a catheter; embolic coils; a bowl or cup shaped neck bridge; an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. It is a called a “bowl-of-spaghetti” type device because the neck bridge can look like a bowl and the embolic coils can look like spaghetti noodles in the bowl.

Abstract: This invention is an intrasaccular aneurysm occlusion device comprising: a net or mesh with a self-expanding resilient proximal portion (which is deployed close to the aneurysm neck) and an expandable flexible distal portion (which is deployed close to the aneurysm dome); and a “string of pearls” of embolic members which are inserted into the net or mesh.

Abstract: This invention is a method which uses 3D medical imaging to estimate the optimal amount of embolic material: to be inserted into a flexible net, mesh, bag, liner, or stent within a cerebral aneurysm sac in order to optimally occlude the aneurysm; or to be inserted directly into the sac in order to optimally occlude the aneurysm.

Abstract: This invention can be embodied in a device for occluding a cerebral aneurysm comprising a series of proximally-and-distally-connected coil loops. This invention can further comprise a stretchable mesh which spans the interiors of these loops. These loops (and the stretchable mesh) overlap to create a coil-and-mesh mass within the aneurysm sac which occludes the aneurysm.

Abstract: This invention is an intrasacular aneurysm occlusion device with a proximal resilient stent which becomes wider than the aneurysm neck and a distal flexible net which is expanded by being filled with embolic members. The stent and the net work together. The stent occludes the aneurysm neck and prevents the device from slipping out. The net conforms to the walls of even an irregularly-shaped aneurysm sac and keeps the stent pressed against the inside of the aneurysm neck. This has advantages over the prior art, especially for aneurysms with irregularly-shaped sacs.

Abstract: This invention is an intrasacular aneurysm occlusion device comprising: two longitudinal wires which are inserted into an aneurysm sac; and mesh which spans between the wires. In an example, the wires can be sinusoidal. In an example, the wires can intersect multiple times to form loops which are spanned by mesh. In an example, the wires can converge and diverge multiple times to form arcuate areas between them which are spanned by mesh. In an example, the device can further comprise a third wire between the first and second wires.

Abstract: This invention gives physicians in situ control to create differences in wall porosity between different areas of a stent wall. This enables a physician to customize the stent within a blood vessel to selectively block blood flow to an aneurysm with a low-porosity area of the stent wall, but allow blood flow to nearby branching vessels through one or more high-porosity areas of the stent wall. The method comprises inserting a stent into a blood vessel and, in situ, expanding the stent in a non-uniform manner, thereby causing one or more areas of the stent wall to have a lower post-expansion porosity than the rest of the stent wall. With this invention, physicians can selectively block blood flow into an aneurysm while maintaining blood flow into nearby branching vessels, even in tortuous and complex vessel configurations.

Abstract: This invention can be embodied in a device for occluding a cerebral aneurysm comprising a series of proximally-and-distally-connected coil loops. This invention can further comprise a stretchable mesh which spans the interiors of these loops. These loops (and the stretchable mesh) overlap to create a coil-and-mesh mass within the aneurysm sac which occludes the aneurysm.

Abstract: This invention is an aneurysm occlusion device with a sequence of shape-changing embolic members which travel through a lumen into an aneurysm sac. The longest axes of these members are substantially parallel to the lumen as within the lumen and longest axes of these members are substantially parallel to the circumference of the neck of the aneurysm after the member exit the lumen. This device can fill a greater percentage of an aneurysm sac, better reduce blood circulation into the aneurysm sac, and better conform to an irregularly-shaped aneurysm sac than coils or single hollow mesh structures.

Abstract: This invention is a stent to reduce blood flow to an aneurysm comprising: (a) an inner member, wherein this inner member is expanded from a first configuration to a second configuration within the parent vessel of an aneurysm, wherein the circumference of the second configuration is larger than the circumference of the first configuration; and (b) an outer member, wherein this outer member is less porous than the inner member, wherein this outer member covers or surrounds a first percentage of the surface area of the inner member when the inner structure is in the first configuration, wherein this outer member covers or surrounds a second percentage of the surface area of the inner member when the inner structure is in the second configuration, and wherein the second percentage less than the first percentage.

Abstract: This invention is a device for occluding an aneurysm comprising: a rotating member that is inserted into, and then rotated within, the aneurysm; and one or more fill members that are dispensed outwards from one or more openings in the rotating member toward the aneurysm walls. Coordination of the rate of rotation of the rotating member with the rate at which the one or more fill members are dispensed from the rotating member can create a densely-packed spiraling mass that fills a higher percentage of the volume of the aneurysm interior than is possible with deployment of coils in the less-directed, relatively-random manner used in the prior art.

Abstract: A device to treat an aneurysm can include a plurality of soft and compressible fill members. A flow conduit can carry the fill members in a liquid flow. A flexible, expandable, and liquid-permeable net or mesh enclosure can be inserted into and to fit within the aneurysm. The net or mesh enclosure can receive and retain the plurality of fill members while openings in the net or mesh enclosure allow enough liquid flow through the net or mesh enclosure to transport the fill members into the net or mesh enclosure. A resulting accumulation of the plurality of fill members within the net or mesh enclosure causes the net or mesh enclosure to expand and to come into contact with and generally conform with an interior wall of the aneurysm. This can substantially occlude the aneurysm and retain the net or mesh enclosure within the aneurysm.

Abstract: This invention is a device and method for reducing blood flow into an aneurysm, especially a cerebral aneurysm, in order to promote therapeutic embolization of the aneurysm. The device comprises: at least one core member that is inserted into the aneurysm; and at least one longitudinal flexible member that is wound repeatedly around the core member within the aneurysm. The longitudinal flexible member is wound around the core member until the rotational accumulation of the flexible member reduces blood flow into the aneurysm and promotes therapeutic embolization of the aneurysm.

Abstract: A device to treat an aneurysm can include a plurality of soft and compressible fill members. A flow conduit can carry the fill members in a liquid flow. A flexible, expandable, and liquid-permeable net or mesh enclosure can be inserted into and to fit within the aneurysm. The net or mesh enclosure can receive and retain the plurality of fill members while openings in the net or mesh enclosure allow enough liquid flow through the net or mesh enclosure to transport the fill members into the net or mesh enclosure. A resulting accumulation of the plurality of fill members within the net or mesh enclosure causes the net or mesh enclosure to expand and to come into contact with and generally conform with an interior wall of the aneurysm. This can substantially occlude the aneurysm and retain the net or mesh enclosure within the aneurysm.