Patents Assigned to Angiotech International AG
  • Compositions and methods for coating medical implants
    Patent number: 8425927
    Abstract: Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: April 23, 2013
    Assignee: Angiotech International AG
    Inventors: William L. Hunter, David M. Gravett, Philip M. Toleikis, Richard T. Liggins, Troy A. E. Loss
  • Compositions and methods for coating medical implants
    Patent number: 8372420
    Abstract: Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: February 12, 2013
    Assignee: Angiotech International AG
    Inventors: William L. Hunter, David M. Gravett, Philip M. Toleikis, Richard T. Liggins, Troy A. E. Loss
  • Compositions and methods for coating medical implants
    Patent number: 8313760
    Abstract: Medical implants are provided which release a fluoropyrimidine or an analog thereof, thereby inhibiting or reducing the incidence of infection associated with the implant.
    Type: Grant
    Filed: April 22, 2008
    Date of Patent: November 20, 2012
    Assignee: Angiotech International AG
    Inventors: William L Hunter, David M Gravett, Philip M Toleikis, Richard T Liggins, Troy A. E. Loss
  • POLYMER COMPOSITIONS AND METHODS FOR THEIR USE
    Publication number: 20120052040
    Abstract: Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
    Type: Application
    Filed: March 22, 2011
    Publication date: March 1, 2012
    Applicant: Angiotech International AG
    Inventors: William L. Hunter, Philip M. Toleikis, David M. Gravelt, Arpita Maiti, Richard T. Liggins, Aniko Takacs-Cox, Rui Avelar, Troy A.E. Loss, Dechi Guan, Kaiyue Wang
  • ANTI-INFECTIVE CATHETERS
    Publication number: 20110150961
    Abstract: Anti-infective catheters are provided. Such catheters comprise a composition that comprises a pyrimidine analog, polyurethane, and cellulose or a cellulose-derived polymer, for example, in form of a coating. In addition, anti-infective compositions and methods of making and using anti-infective catheters are provided.
    Type: Application
    Filed: February 18, 2009
    Publication date: June 23, 2011
    Applicant: Angiotech International AG
    Inventors: Joy Erann Perry, Alexandra M. Chamberlain, Scott F. Rosebrough
  • ELECTRICAL DEVICES AND ANTI-SCARRING AGENTS
    Publication number: 20100268288
    Abstract: Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the devices are implanted within an animal.
    Type: Application
    Filed: February 10, 2010
    Publication date: October 21, 2010
    Applicant: Angiotech International AG
    Inventors: William L. Hunter, David M. Gravett, Philip M. Toleikis, Arpita Maiti
  • SILK STENT GRAFTS
    Publication number: 20100222863
    Abstract: Silk-containing stent grafts are provided comprising an endoluminal stent and a graft, wherein the silk induces the in vivo adhesion of the stent graft to vessel walls, or, otherwise induces or accelerates an in vivo fibrotic reaction causing said stent graft to adhere to vessel wall. Also provided are methods for making and using such stent grafts.
    Type: Application
    Filed: March 31, 2010
    Publication date: September 2, 2010
    Applicant: Angiotech International AG
    Inventors: David M. Gravett, Pierre E. Signore, Kaiyue Wang, Philip M. Toleikis, Dechi Guan, Zengxuan Hu, Arpita Maiti
  • IMPLANTABLE SENSORS AND IMPLANTABLE PUMPS AND ANTI-SCARRING AGENTS
    Publication number: 20100092536
    Abstract: Pumps and sensors for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the pumps and sensors are implanted within an animal.
    Type: Application
    Filed: May 11, 2009
    Publication date: April 15, 2010
    Applicant: Angiotech International AG
    Inventors: William L. Hunter, David M. Gravett, Philip M. Toleikis, Arpita Maiti
  • COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS
    Publication number: 20100082003
    Abstract: Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.
    Type: Application
    Filed: September 3, 2009
    Publication date: April 1, 2010
    Applicant: Angiotech International AG
    Inventors: William L. Hunter, David M. Gravett, Philip M. Toleikis, Richard T. Liggins, Troy A.E. Loss
  • electrical devices, anti-scarring agents, and therapeutic compositions
    Publication number: 20090280153
    Abstract: Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the devices are implanted within an animal.
    Type: Application
    Filed: March 31, 2006
    Publication date: November 12, 2009
    Applicant: Angiotech International AG
    Inventors: William L. Hunter, Philip M. Toleikis, David M. Gravett, Arpita Maiti, Richard T. Liggins, Aniko Takacs-Cox, Rui Avelar, Pierre E. Signore, Troy A. E. Loss, Anne Hutchinson, Gaye McDonald-Jones, Fara Lakhani
  • SOFT TISSUE IMPLANTS AND ANTI-SCARRING AGENTS
    Publication number: 20090214652
    Abstract: Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.
    Type: Application
    Filed: April 16, 2009
    Publication date: August 27, 2009
    Applicant: Angiotech International AG
    Inventors: William L. Hunter, David M. Gravett, Philip M. Toleikis, Arpita Maiti
  • COMPOSITIONS AND METHODS FOR TREATING CONTRACTURE
    Publication number: 20090203632
    Abstract: A method for treating contracture is provided that includes administering to a patient in need thereof a composition that includes a therapeutic agent effective in treating contracture. Compositions, devices, and kits for use in treating contracture are also described.
    Type: Application
    Filed: October 8, 2008
    Publication date: August 13, 2009
    Applicant: Angiotech International AG
    Inventors: Rui Avelar, Richard T. Liggins, Philip M. Toleikis, Troy A. E. Loss, David M. Gravett, Arpita Maiti
  • COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS
    Publication number: 20090060973
    Abstract: Medical implants are provided which release a fluoropyrimidine or an analog thereof, thereby inhibiting or reducing the incidence of infection associated with the implant.
    Type: Application
    Filed: April 22, 2008
    Publication date: March 5, 2009
    Applicant: Angiotech International AG
    Inventors: William L. Hunter, David M. Gravett, Philip M. Toleikis, Richard T. Liggins, Troy A.E. Loss
  • COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS
    Publication number: 20080241217
    Abstract: Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.
    Type: Application
    Filed: February 22, 2008
    Publication date: October 2, 2008
    Applicant: Angiotech International AG
    Inventors: William L. Hunter, David M. Gravett, Philip M. Toleikis, Richard T. Liggins, Troy A.E. Loss
  • Compositions and methods for treating or preventing imflammatory diseases
    Publication number: 20080153900
    Abstract: Methods and compositions for treating or preventing inflammatory diseases such as psoriasis or multiple sclerosis are provided, comprising the step of delivering to the site of inflammation an anti-microtubule agent, or analogue or derivative thereof.
    Type: Application
    Filed: August 10, 2007
    Publication date: June 26, 2008
    Applicant: Angiotech International AG
    Inventor: William L. Hunter
  • Compositions and methods for coating medical implants
    Publication number: 20080145514
    Abstract: Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.
    Type: Application
    Filed: July 31, 2007
    Publication date: June 19, 2008
    Applicant: Angiotech International AG
    Inventors: William L. Hunter, David M. Gravett, Philip M. Toleikis, Richard T. Liggins, Troy A. E. Loss
  • Microparticles With High Loadings Of A Bioactive Agent
    Publication number: 20080124400
    Abstract: The present invention discloses compositions, devices and methods for the production, use and administration of compositions that comprise microparticles that are loaded with a drug at a concentration of greater than 50% (weight drug/weight microparticle).
    Type: Application
    Filed: June 24, 2005
    Publication date: May 29, 2008
    Applicant: Angiotech International AG
    Inventors: Richard T. Liggins, Philip M. Toleikis, Dechi Guan
  • Compositions and methods for treating or preventing inflammatory diseases
    Publication number: 20080113035
    Abstract: Methods and compositions for treating or preventing inflammatory diseases such as psoriasis or multiple sclerosis are provided, comprising the step of delivering to the site of inflammation an anti-microtubule agent, or analogue or derivative thereof.
    Type: Application
    Filed: August 10, 2007
    Publication date: May 15, 2008
    Applicant: Angiotech International AG
    Inventor: William L. Hunter
  • Compositions and methods for coating medical implants
    Publication number: 20080113000
    Abstract: Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.
    Type: Application
    Filed: July 31, 2007
    Publication date: May 15, 2008
    Applicant: Angiotech International AG
    Inventors: William L. Hunter, David M. Gravett, Philip M. Toleikis, Richard T. Liggins, Troy A.E. Loss
  • Stents combined with paclitaxel derivatives
    Patent number: H2260
    Abstract: Stents are used in combination with a paclitaxel derivative in order to inhibit scarring that may otherwise occur when the implant is placed within an animal. Suitable implants include vascular stents, esophageal stents, tracheal or bronchial stents, gastrointestinal stents, genital-urinary stents, nasal and sinus stents, and ENT stents.
    Type: Grant
    Filed: February 17, 2006
    Date of Patent: July 5, 2011
    Assignee: Angiotech International AG
    Inventor: Philip M. Toleikis