Abstract: The instant application provides methods and related compositions pertaining to the identification of resistance to anticancer treatment in. a patient. In a particular embodiment, the invention provides biomarkers for the identification of resistance to anticancer treatment in a breast cancer patient, wherein a reduced expression of a MEDIATOR and/or SWI/SNF complex gene in the breast cancer cells of the patient indicates that the breast cancer cells in the patient may be successfully treated with a PI3K and/or mTOR inhibitor.
Type:
Application
Filed:
April 4, 2012
Publication date:
September 25, 2014
Applicant:
Stichting het Nederlands Kanker Instituut - Antoni van Leeuwenhoek ziekenhuis
Inventors:
Rene Bernards, Sidong Huang, Michael Holzel, Katrien Berns
Abstract: A pair of complementary articles of clothing, such as socks, that can be detachably connected to each other. The detachable connection can be made by first and second complementary connecting elements, which are each fastened to the article of clothing by a carrier element, wherein one of the ends of each carrier element forms a gripping area without a connecting function, so that the connection between the first and the second connecting element can be detached by pulling on the gripping areas of the carrier elements.
Abstract: A method for detecting the on and off states of a Parkinson patient, including obtaining inertial data from a patient and verifying if the patient is in an on or off state by using a transformation of the obtained inertial data which uses a model derived from a set of stored data referred to patients in on state and patients in off state.
Type:
Application
Filed:
January 8, 2010
Publication date:
July 14, 2011
Applicants:
FUNDACIO PRIVADA HOSPITAL COMARCAL DE SANT ANTONI ABAT DE VILANOVA I LA GELTRU, UNIVERSITAT POLITECNICA DE CATALUNYA
Inventors:
Manuel Alejandro RODRÍGUEZ MOLINERO, Joan Cabestany Moncusi, David Andrés Pérez Martínez, Albert Samà Monsonís, César Pavel Gálvez Barrón, Andreu Catalá Mallofré, Cecilio Angulo Bahón, Carlos Pérez López, Jaime Romagosa Cabús
Abstract: The invention relates to a device for washing of eggs in order to remove adhering dirt in which egg transport means and egg guiding means are present. The egg transport means and egg guiding means cooperate and form egg rotation means which cause an egg to rotate substantially around its shortest main axis; dirt removal is achieved with use of one or more brushes and a washing liquid. The egg's longest main axis thereby remains substantially in a plane parallel to the direction of transport of the eggs, said plane being perpendicular to the plane going through the centerlines of the egg guiding means.
Type:
Grant
Filed:
April 4, 1986
Date of Patent:
June 14, 1988
Assignee:
Antonis
Inventors:
Hermanus C. Poel, Martinus J. M. Boumans, Metheus E. Antonis