Patents Assigned to Applied Precision, Inc.
  • Publication number: 20120033895
    Abstract: A system and method of image processing employ mathematical deconvolution to estimate the magnitude and location of a target object within an image. Both the nature of internal reflections and the convolution process by which each internal reflection contributes to blurring of the acquired image data may be measured and modeled. In accordance with mathematical deconvolution techniques, the combined effects of these internal reflections may be reduced to the extent that respective contributions of the target object and each individual reflection may be distinguished and quantified.
    Type: Application
    Filed: October 13, 2011
    Publication date: February 9, 2012
    Applicant: APPLIED PRECISION, INC.
    Inventor: CARL S. BROWN
  • Patent number: 8041146
    Abstract: A system and method of image processing employ mathematical deconvolution to estimate the magnitude and location of a target object within an image. Both the nature of internal reflections and the convolution process by which each internal reflection contributes to blurring of the acquired image data may be measured and modeled. In accordance with mathematical deconvolution techniques, the combined effects of these internal reflections may be reduced to the extend that respective contributions of the target object and each individual reflection may be distinguished and quantified.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: October 18, 2011
    Assignee: Applied Precision, Inc
    Inventor: Carl S. Brown
  • Publication number: 20100208061
    Abstract: An apparatus for scanning a biometric device includes a camera that scans the biometric device to generate images, and a computer that extracts data from the images. The computer measures three-dimensional locations of at least three different positions on a surface of the biometric device, determines one of a virtual approximation plane and a curved surface with respect to the surface of the biometric device based on the measured three-dimensional locations, determines imaging locations of two or more panels disposed on the biometric device based on the one of the virtual approximation plane and the curved surface, obtains individual images of the two or more panels by scanning the biometric device based on the determined imaging locations, and extracts overall data of the biometric device from the individual images of the two or more panels.
    Type: Application
    Filed: February 11, 2010
    Publication date: August 19, 2010
    Applicants: SAMSUNG ELECTRONICS CO., LTD., APPLIED PRECISION, INC.
    Inventors: Kyu-sang LEE, Carl S. BROWN, Kyla TEPLITZ, Steve GOODSON
  • Patent number: 7770402
    Abstract: A system and method of cooling a CCD camera may employ a composite material housing design that allows the cold side of a TEC to be mounted relatively close to the CCD and the hot side of the TEC to be isolated from the housing cavity in which the CCD resides. An efficient heat transfer path may facilitate cooling the CCD to a predetermined or selected operating temperature and isolate the CCD from the heat loads generated by operation the TEC.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: August 10, 2010
    Assignee: Applied Precision, Inc.
    Inventor: Steven C. Quarre
  • Patent number: 7705323
    Abstract: A microscope stage with a flexural axis may exhibit predictable flexure characteristics and limited cross-coupling translations. Z motion of a Z plate proximate to a Z actuator may be substantially linear, while a distal side of the Z plate may be allowed to rotate about a hinge axis associated with a flexural component.
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: April 27, 2010
    Assignee: Applied Precision, Inc.
    Inventors: Steven C. Quarre, John Malcolm
  • Patent number: 7683345
    Abstract: A system and method employing photokinetic techniques in cell biology imaging applications are disclosed. Systems and methods of acquiring image data of an object may comprise: selectively inducing photoactivation of material at a site on the object; performing an optical axis integration scan; simultaneously executing a time delay integration scan sequence; and processing acquired image data in accordance with one or more desired analyses. Various methodologies and applications may include, inter alia, selective photobleaching of a site on the object, diffusion rate, velocity, and wave-front propagation analyses, multi-dimensional analyses of dispersion characteristics, biomolecular binding in cellular organelles, and photoactivation assisted systematic image segmentation for the study of cellular components.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: March 23, 2010
    Assignee: Applied Precision, Inc.
    Inventors: Paul C. Goodwin, Carl S. Brown, Steven A. Reese
  • Publication number: 20090206238
    Abstract: A new optical substrate design allows a target to be illuminated with minimal illumination of undesired surfaces within the image collection ray path.
    Type: Application
    Filed: December 30, 2008
    Publication date: August 20, 2009
    Applicant: Applied Precision, Inc. Delaware corporation
    Inventors: Carl S. Brown, Steven A. Reese
  • Publication number: 20090109416
    Abstract: Methods and apparatus are described for delivering index-matching immersion liquid in high numerical-aperture optical microscopy and lithography. An array of immersion liquid droplets is delivered to a specimen substrate or specimen substrate cover by an immersion liquid printing apparatus. An immersion liquid reservoir provides immersion liquid to the printer by a precision pump. The printer delivers immersion liquid to the substrate or substrate cover in arrays of immersion liquid droplets of defined volumes and array patterns. The volumes and patterns of array droplets delivered to the substrate or substrate cover are optimized to maintain adequate immersion liquid between the substrate or substrate cover and an immersion objective while avoiding the formation of air bubbles in the immersion liquid and the accumulation of excess volumes of immersion liquid.
    Type: Application
    Filed: September 11, 2008
    Publication date: April 30, 2009
    Applicant: APPLIED PRECISION, INC.
    Inventors: WILLIAM M. DOUGHERTY, Paul C. Goodwin, Steven A. Reese, David A. Stewart
  • Publication number: 20090097110
    Abstract: A system and method of generating and acquiring phase contrast microscope images while minimizing interference with the intensity and optical quality of other microscopy modalities employing polarization and attenuation strategies for phase microscopy applications. A plane polarizing objective phase ring may be used in conjunction with a phase microscopy apparatus. Attenuated light may be controlled such that transparency may be selectively provided with respect to light in a predetermined plane. Illumination outside of the predetermined plane may be selected for phase microscopy applications. Accordingly, a polarizing objective phase ring effective for enabling polarized phase microscopy may reduce interfere with normal usage of the microscope for other applications such as, for example, fluorescence microscopy.
    Type: Application
    Filed: December 16, 2008
    Publication date: April 16, 2009
    Applicant: Applied Precision, Inc.
    Inventor: PAUL C. GOODWIN
  • Patent number: 6414477
    Abstract: A method for quantitatively determining probe card errors relying on merging data sets from a probe card analysis machine and a scrub mark analysis machine. Minimizing error values related to the data sets provides an indication of probe card/probe machine combination tolerance.
    Type: Grant
    Filed: June 7, 1999
    Date of Patent: July 2, 2002
    Assignee: Applied Precision, Inc.
    Inventor: John Strom
  • Patent number: 5899437
    Abstract: A cam actuated valve method and apparatus utilize an electronically controlled stepper motor driving a cam. A diaphragm type low flow, high accuracy diaphragm valve is positioned off axis with respect to the cam. A transmission translates linear motion of the cam to the valve diaphragm. High accuracy is maintained because the transmission is preloaded by pressure within the valve and the valve diaphragm.
    Type: Grant
    Filed: December 12, 1997
    Date of Patent: May 4, 1999
    Assignee: Applied Precision, Inc.
    Inventor: Steven C. Quarre
  • Patent number: 5831443
    Abstract: A probe card array check plate is provided with transition zones to prevent a semi-conductor probe from impacting an epoxy joint in the check plate during an over travel test. The transition zone is in the form of beveled edges or tapers between first and second testing surfaces. In alternate embodiments, two or more different types of testing surfaces are juxta positioned, or an optical measurement window is made sufficiently large to prevent an over traveling probe tip from entering an epoxied area.
    Type: Grant
    Filed: June 5, 1996
    Date of Patent: November 3, 1998
    Assignee: Applied Precision, Inc.
    Inventors: Steven C. Quarre, John P. Stewart
  • Patent number: 5812310
    Abstract: A high accuracy, orthogonal motion stage for microscopes and the like uses three frames for orthogonal motion. The lower most frame has provided thereon a series of downwardly depending ramps. An actuator plate having correspondingly positioned, upwardly directed ramps is translated with respect to the lower most frame to raise and lower the frames.
    Type: Grant
    Filed: October 16, 1996
    Date of Patent: September 22, 1998
    Assignee: Applied Precision, Inc.
    Inventors: John P. Stewart, Thurmond R. Smith, Gary M. Gunderson
  • Patent number: 5744884
    Abstract: A linear motion micropositioning device employs a housing containing fixed, electrically excited stators. A rotating permanent magnet rotor is directly attached to a spindle of a precision lead screw. The stators are provided with sufficient axial depth to permit the rotor to rotate and reciprocate axially while under continuous magnetic influence of the stators.
    Type: Grant
    Filed: October 17, 1995
    Date of Patent: April 28, 1998
    Assignee: Applied Precision, Inc.
    Inventor: Gregory J. Gerhard
  • Patent number: 5684628
    Abstract: An orthogonal motion stage provides Z axis motion, along an optical axis independently of translational motion in an orthogonal, X-Y axis reference plane. Conversely, motion in the X-Y reference plane does not induce unwanted motion in the Z axis. Straight line mechanisms interconnect the Z axis carrier to a base plate. Flexible connections are used in the straight line mechanisms to ensure accurate orthogonal motion.
    Type: Grant
    Filed: February 15, 1995
    Date of Patent: November 4, 1997
    Assignee: Applied Precision, Inc.
    Inventor: Gregory J. Gerhard
  • Patent number: 5508629
    Abstract: A method and apparatus for inspecting integrated circuit probe cards in which the probe points of the probe card are scanned across a checkplate having a conductivity transition border. The impedances between the probe points and the checkplate as they cross the conductivity transition border are measured to determine when the probe points cross the border. The positions of the probe card when each of the probe points crosses the border are measured to determine the positions of the probe points relative to each other. In one embodiment, the checkplate is formed by a square conductive plate having three quadrants of insulated material and a single quadrant of conductive material mounted on its upper surface. These conductive strips connected to the conductive plate are positioned between the quadrants of insulative material to form the conductivity transition border. In other embodiments, multiple parallel strips or a single dot of conductive material are surrounded by insulative material.
    Type: Grant
    Filed: April 22, 1991
    Date of Patent: April 16, 1996
    Assignee: Applied Precision, Inc.
    Inventors: John P. Stewart, Ronald C. Seubert, Donald B. Snow
  • Patent number: 5060371
    Abstract: A method and apparatus for inspecting integrated circuit probe cards in which the probe points of the probe card are scanned across a checkplate having a conductivity transition border. The impedances between the probe points and the checkplate as they cross the conductivity transition border are measured to determine when the probe points cross the border. The positions of the probe card when each of the probe points crosses the border are measured to determine the positions of the probe points relative to each other. In one embodiment, the checkplate is formed by a square conductive plate having three quadrants of insulated material and a single quadrant of conductive material mounted on its upper surface. These conductive strips connected to the conductive plate are positioned between the quadrants of insulative material to form the conductivity transition border. In other embodiments, multiple parallel strips or a single dot of conductive material are surrounded by insulative material.
    Type: Grant
    Filed: March 1, 1990
    Date of Patent: October 29, 1991
    Assignee: Applied Precision, Inc.
    Inventors: John P. Stewart, Ronald C. Seubert, Donald B. Snow
  • Patent number: 4918374
    Abstract: A method and apparatus for inspecting integrated circuit probe cards in which the probe points of the probe card are scanned across a checkplate having a conductivity transition border. The impedances between the probe points and the checkplate as they cross the conductivity transition border are measured to determine when the probe points cross the border. The positions of the probe card when each of the probe points crosses the border are measured to determine the positions of the probe points relative to each other. In one embodiment, the checkplate is formed by a square conductive plate having three quadrants of insulated material and a single quadrant of conductive material mounted on its upper surface. These conductive strips connected to the conductive plate are positioned between the quadrants of insulative material to form the conductivity transition border. In other embodiments, multiple parallel strips or a single dot of conductive material are surrounded by insulative material.
    Type: Grant
    Filed: October 5, 1988
    Date of Patent: April 17, 1990
    Assignee: Applied Precision, Inc.
    Inventors: John P. Stewart, Ronald C. Seubert, Donald B. Snow