Abstract: Solvent free epoxy system that includes: a hardener compound H comprising: a molecular structure (Y1—R1—Y2), wherein R1 is an ionic moiety Y1 is a nucleophilic group and Y2 nucleophilic group; and an ionic moiety A acting as a counter ion to R1; and an epoxy compound E comprising: a molecular structure (Z1—R2—Z2), wherein R2 is an ionic moiety, Z1 comprises an epoxide group, and Z2 comprises an epoxide group; and an ionic moiety B acting as a counter ion to R2. In embodiments, the epoxy compound E and/or the hardener H is comprised in a solvent-less ionic liquid. The systems can further include accelerators, crosslinkers, plasticizers, inhibitors, ionic hydrophobic and/or super-hydrophobic compounds, ionic hydrophilic compounds, ionic transitional hydrophobic/hydrophilic compounds, biological active compounds, and/or plasticizer compounds. Polymers made from the disclosed epoxy systems and their methods of used.
Type:
Grant
Filed:
April 9, 2021
Date of Patent:
January 2, 2024
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Inventors:
Cody Friesen, Jose Antonio Bautista-Martinez, Mykhaylo Goncharenko, Paul Johnson
Abstract: In certain embodiments, the present invention provides a poultry vaccine comprising an antigenic protein comprising a PlcC protein unit that is operably linked to a peptide linker that is operably linked to a NetB protein unit, where the vaccine is effective in stimulating a protective cellular and/or humoral immune response to C. perfringens. Methods are also provided for making the vaccine and for vaccinating poultry by administering such a vaccine.
Type:
Grant
Filed:
December 27, 2022
Date of Patent:
January 2, 2024
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF ARIZONA STATE UNIVERSITY
Inventors:
Kenneth Roland, Andrew Diamos, Hugh Mason
Abstract: A wireless multi-channel implantable device. In some embodiments, the system includes: a wireless reception element, for receiving power wirelessly through tissue of a subject; a power management and storage circuit, for storing a portion of the received power; and a control circuit for controlling the delivery of current from the power management and storage circuit to each of a plurality of stimulation electrodes individually, based on a modulation of the received power.
Type:
Application
Filed:
June 27, 2023
Publication date:
December 28, 2023
Applicant:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Inventors:
Jennifer BLAIN CHRISTEN, Shiyi LIU, Ahmed Abed BENBUK, Daniel GULICK
Abstract: Iridium, rhodium, and platinum complexes suitable for use as phosphorescent emitters or as delayed fluorescent and phosphorescent emitters having the following structures:
Type:
Grant
Filed:
March 25, 2021
Date of Patent:
December 26, 2023
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Abstract: Provided herein are methods of detecting exosomes, including unlabeled exosomes. In some embodiments, the methods include disposing a fluidic sample that comprises a plurality of exosomes in a chamber that is positioned at least partially within a fluidic device in which an inner surface of the chamber comprises a first set of exosome binding moieties that are capable of binding the exosomes. In some embodiments, the methods also include binding a portion of the plurality of exosomes to a portion of the first set of exosome binding moieties to produce surface-bound exosomes, introducing an incident light toward the inner surface of the chamber prior to, concurrent with, and/or after, producing the surface-bound exosomes, and detecting light scattered by the surface-bound exosomes to produce a set of exosome imaging data. Related fluidic devices, systems, and computer readable media are also provided.
Type:
Application
Filed:
June 1, 2023
Publication date:
December 21, 2023
Applicant:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: An additive manufacturing process for forming a metallic layer on the surface of the substrate includes fabricating a substrate from a polymerizable composition by a stereolithographic process, and contacting the reactive surface with an aqueous solution including a metal precursor. The metal precursor includes a metal, and the polymerizable composition includes a multiplicity of multifunctional components. Each multifunctional component includes a reactive moiety extending from a surface of the substrate to form a reactive surface. An interface between the reactive surface and the aqueous solution is selectively irradiated to form nanoparticles including the metal in a desired pattern. The nanoparticles are chemically coupled to the reactive surface by reactive moieties, thereby forming a metallic layer on the surface of the substrate.
Type:
Application
Filed:
July 27, 2023
Publication date:
December 21, 2023
Applicant:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: A full-stack neural network obfuscation framework obfuscates a neural network architecture while preserving its functionality with very limited performance overhead. The framework includes obfuscating parameters or “knobs”, including layer branching, layer widening, selective fusion and schedule pruning, that increase the number of operators, reduce/increase the latency, and number of cache and DRAM accesses. In addition, a genetic algorithm-based approach is adopted to orchestrate the combination of obfuscating knobs to achieve the best obfuscating effect on the layer sequence and dimension parameters so that the architecture information cannot be successfully extracted.
Type:
Application
Filed:
June 9, 2023
Publication date:
December 14, 2023
Applicant:
Arizona Board of Regents on behalf of Arizona State University
Abstract: Provided herein are qPCR-based methods for quantitatively detecting and differentiating between live and dead pathogenic bacteria such as carbapenem-resistant Enterobacteriaceae (CRE). Also provided herein are simple, fast, and reliable genomic DNA extraction methods with improved efficiency.
Type:
Grant
Filed:
June 11, 2021
Date of Patent:
December 12, 2023
Assignees:
Arizona Board of Regents on behalf of Arizona State University, Mayo Foundation for Medical Education and Research
Inventors:
Joshua LaBaer, Vel Murugan, Merica Vorachitti, Rahul Pannala, Douglas Faigel
Abstract: Described herein are systems and methods for the depolymerization of polyethylene-based plastics. In one embodiment, a method is disclosed that comprises combining a polyethylene-based plastic with a solvent in a reactor to generate a plastic solvent mixture, heating the plastic solvent mixture in the reactor, and fractionating the plastic solvent mixture into a gas phase product, a solid phase product, and a liquid phase product. In another embodiment, a system is disclosed that comprises a solvent, and a reactor configured to receive the polyethylene-based plastic and the solvent and convert the polyethylene-based plastic into a gas phase product, a solid phase product, and a liquid phase product, the reactor being configured to operate at a temperature greater than 275° C. and at a pressure greater than 2 megapascals.
Type:
Grant
Filed:
July 7, 2022
Date of Patent:
December 12, 2023
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: A computer-implemented SynF (Synthetic Infrastructure) model is designed to estimate the location and characteristics of urban water and power distribution networks, estimate how those networks are interconnected and connect to buildings and transportation systems, and assess how failures propagate within and across the systems. The model was designed using Phoenix metro area cities but has been extended to other cities.
Type:
Application
Filed:
June 2, 2023
Publication date:
December 7, 2023
Applicant:
Arizona Board of Regents on Behalf of Arizona State University
Inventors:
Mikhail Chester, SK Nasir Ahmad, Nathan Johnson, Ryan Hoff
Abstract: This disclosure includes systems and methods for extracting water vapor from atmospheric air and, more particularly, but not by way of limitation, systems and methods for optimizing liquid water production from air, in some instances, taking into account diurnal variations. The systems comprise an adsorption zone and a desorption zone, an actuator to move a desiccant between the adsorption zone and the desorption zone. The liquid water production is optimized based, at least in part, on measurements of one or more of: an ambient air temperature, ambient air relative humidity, and a level of solar insolation.
Type:
Application
Filed:
June 6, 2023
Publication date:
December 7, 2023
Applicant:
Arizona Board of Regents on Behalf of Arizona State University
Abstract: A method for deep learning video microscopy-based antimicrobial susceptibility testing of a bacterial strain in a sample by acquiring image sequences of individual bacterial cells of the bacterial strain in a subject sample before, during, and after exposure to each antibiotic at different concentrations. The image sequences are compressed into static images while preserving essential phenotypic features. Data representing the static images is input into a pre-trained deep learning (DL) model which generates output data; and antimicrobial susceptibility for the bacterial strain is determined from the output data.
Type:
Grant
Filed:
April 5, 2018
Date of Patent:
December 5, 2023
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Abstract: Platinum complexes suitable for use as phosphorescent emitters or as delayed fluorescent and phosphorescent emitters having the following structure:
Type:
Grant
Filed:
March 25, 2021
Date of Patent:
December 5, 2023
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Abstract: Provided herein are methods of detecting and measuring disease-associated analytes such as proteins and antibodies in a sweat sample. Also provided are methods of determining and monitoring the disease state or physiological condition of a subject using small sweat samples.
Type:
Grant
Filed:
July 11, 2017
Date of Patent:
December 5, 2023
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Inventors:
Benjamin Katchman, Karen Anderson, Jennifer Blain Christen
Abstract: Various embodiments of a system and associated method for determining a volume of surgical freedom using a plurality of three-dimensional extrema points along a surgical corridor in relation to a structure of interest are disclosed herein.
Type:
Grant
Filed:
September 10, 2021
Date of Patent:
December 5, 2023
Assignees:
Dignity Health, Arizona Board of Regents on Behalf of Arizona State University
Inventors:
Lena Mary Houlihan, David Naughton, Mark C. Preul
Abstract: A device for neurostimulation having an extendable headband having first and second arms each having a proximal end and a distal end, the two arms connected to one another at the proximal ends via an extension mechanism, an electrode band having first and second ends, the first end rotatably connected to a point on the first arm, and the second end rotatably connected to a point on the second arm, and first and second electrodes slidably positioned on the electrode band configured to deliver neurostimulation to a subject. A method of encouraging a behavior of a subject, for example physical activity, is also described.
Type:
Application
Filed:
May 26, 2023
Publication date:
November 30, 2023
Applicant:
Arizona Board of Regents on behalf of Arizona State University
Abstract: Adhering to the objective of modelling and selecting the most optimal winding configuration for a high frequency planar transformer (HFPT) for auxiliary charging systems for more electric aircrafts (MEA) this disclosure elucidates numerous fabrication and design-based constraints and correlations to enable parametric modelling of various magnetic components. This disclosure characterizes possible winding configurations for HFPT employed in a bidirectional CUE DC/DC converter. A detailed analytical study is presented for each component and verified using several instances of 3D Finite Element Analysis (FEA) based model to synthesize the effective field and current density distribution in the windings. Several design-based trade-offs are graphically explained with various criteria pertaining to optimal winding selection to study the interdependence of the resultant parameters on hardware specifications, such as the PCB thickness and its fabrication layout, air gaps and conductor thickness.
Type:
Application
Filed:
May 25, 2023
Publication date:
November 30, 2023
Applicant:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: The operational characteristics of a cyber-physical system (CPS) may deviate from the certified system due to intended (in case of cheating) or unintended (wear and tear) reasons. A computer-implemented certification system makes test case search aware of the multidimensional interactions between the cyber and physical subsystems and addresses practical dynamical system problems like Zeno behavior and dynamical model divergence. The system dynamically modulates an input search space by predicting and limiting input variations that can potentially cause divergence or Zeno behavior.
Type:
Application
Filed:
May 25, 2023
Publication date:
November 30, 2023
Applicant:
Arizona Board of Regents on Behalf of Arizona State University
Abstract: The present invention relates to a truncated form of chlorotoxin and chlorotoxin-like protein that are useful for glioma immunotherapy, in particular the treatment of glioblastoma. Thus, the invention also encompasses a therapeutic fusion protein comprising the truncated form of chlorotoxin and chlorotoxin-like protein, its methods of use, and its method of production.
Type:
Application
Filed:
May 25, 2023
Publication date:
November 30, 2023
Applicant:
Arizona Board of Regents on Behalf of Arizona State University
Inventors:
Tsafrir S. LEKET-MOR, Braeden SCHAEFER, Rebecca COOK, Joseph BLATTMAN