Abstract: Methods and systems are provided for detecting mechanophore damage in a composite material where the mechanophores are embedded in a matrix of the composite material. A mechanical load is applied to the composite material. A damage precursor signal is generated as a result of the mechanical load and is detected before yield of the mechanophore embedded composite material. Detecting the damage precursor signal may include illuminating the mechanophore embedded composite material with UV light to excite the embedded mechanophores, capturing fluorescent emissions of the embedded mechanophores with a UV camera, and filtering light received at the UV camera based on an emission wavelength of the mechanophores. Alternatively, the damage precursor signal may be detected using spectra from an evanescent wave distorted by the mechanophore embedded composite material using an attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) system.

Abstract: Ligands and methods for selectively binding hypermethylated DNA from a sample. The ligands include a CG-region binding molecule-conjugated resin derived from the aminoglycoside antibiotic amikacin. Furthermore, the CG-region binding molecule may be conjugated to the resin with a crosslinker and/or may be modified with one or more of long chain and short chain alkyl, aryl, piperazinyl, piperidyl, and pyrrolidyl groups. Such ligands are used in methods for contacting a sample to thereby selectively bind hypermethylated DNA.

Abstract: Various embodiments of a four-step intra-LayBack handover protocol within a given gateway in an SDN-LayBack architecture are disclosed. The intra-LayBack handover reduces the signaling load by 60% in comparison with conventional LTE handover within a given serving gateway.

Abstract: Methods for antibody profiling and epitope mapping are provided herein. More particularly, methods for screening and mapping epitopes of candidate antibodies and protein target identification are provided herein.

Abstract: Systems and methods are described for facilitating non-verbal communication. An electronic processor receives data from the hand-gesture sensor indicative of one or more gestures performed by a user, determines at least one word or phrase corresponding to the data from the hand-gestures sensor, and outputs a text representation of the at least one word or phrase on the display screen. Some systems output the text representation as a natural language sentence based on the data from the hand-gesture sensor and linguistic prosody information determined based, at least in part, on image data of the user captured while performing the one or more gesture. Some systems also includes at least one brain sensor and generate an alternative natural language text sentence in response to detecting a signal from the brain sensor indicative of a contradiction response after displaying the natural language text sentence on the display screen.

Abstract: Compounds and methods involving inhibition of the enzymatic activity of QSOX1 (FIG. 13). The compounds and methods can be used in treatment of neoplastic cells, for example, to suppress tumor growth and invasion in a variety of cancers, including but not limited to myeloma and cancers of the breast, kidney, and pancreas.

Abstract: Large intelligent surfaces (LISs) with sparse channel sensors are provided. Embodiments described herein provide efficient solutions for these problems by leveraging tools from compressive sensing and deep learning. Consequently, an LIS architecture based on sparse channel sensors is provided where all LIS elements are passive reconfigurable elements except for a few elements that are active (e.g., connected to baseband). Two solutions are developed that design LIS reflection matrices with negligible training overhead. First, compressive sensing tools are leveraged to construct channels at all the LIS elements from the channels seen only at the active elements. These full channels can then be used to design the LIS reflection matrices with no training overhead.

Abstract: Embodiments of an improved light-direction detection (LDD) device are described herein. The LDD device includes a substrate and at least one predefined structure formed along the substrate by stacking metal layers, contacts, and vias available in the manufacturing process of the device. The predefined structure is formed along a photodiode pair to collectively define an optical sensor configured to detect direction of incident light without need for off-chip components. The device accommodates light direction detection in two or more orthogonal planes.

Abstract: Various embodiments of systems and methods for adaptive video subsampling for energy-efficient object detection are disclosed herein.

Abstract: A method for affine abstraction of intention models of vehicles is disclosed.

Abstract: Various embodiments of systems and methods for mobile crowd sensing applications are disclosed herein.

Abstract: A field-programmable gate array (FPGA) with reconfigurable threshold logic gates for improved performance, power, and area (PPA) is provided. This disclosure describes a new architecture for an FPGA, referred to as threshold logic FPGA (TLFPGA), that integrates a conventional lookup table (LUT) with a complementary metal-oxide-semiconductor (CMOS) digital implementation of a binary perceptron, referred to as a threshold logic cell (TLC). The TLFPGA design described herein, combined with a new logic mapping algorithm that exploits the presence of both conventional LUTs and TLCs within the basic logic element (BLE) block, achieves significant improvements in all the metrics of PPA. The TLCs of embodiments described herein are capable of implementing a complex threshold function, which if implemented using conventional gates would require several levels of logic gates. The TLCs only require seven static random-access memory (SRAM) cells and are significantly faster than the conventional LUTs.

Abstract: An improved method for bounded error estimation of vehicle states is disclosed.

Abstract: Tetradentate platinum complexes of Formulas I and II suitable for phosphorescent or delayed fluorescent and phosphorescent emitters in display and lighting applications.

Abstract: Embodiments of a vehicular system with an L-shaped infotainment display for reducing driver distraction and improving safety are disclosed.

Abstract: The invention provides compounds having the general formula I: and pharmaceutically acceptable salts thereof, wherein the variables R1, R2, R3, R4, subscript m and n, have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

Abstract: Power converter circuitry includes a direct current (DC) input comprising a first DC input node and a second DC input node, an alternating current (AC) output comprising a first AC output node coupled to the first DC input node and a second AC output node, a first boost switch coupled between the second DC input node and a boost intermediate node, a second boost switch coupled between the boost intermediate node and a common node, a boost inductor coupled between the boost intermediate node and the first DC input node, a link capacitor coupled between the second DC input node and the common node, a first half-bridge switch coupled between the second DC input node and a half-bridge intermediate node, a second half-bridge switch coupled between the half-bridge intermediate node and the common node, and a half-bridge inductor coupled between the half-bridge intermediate node and the second AC output node.

Abstract: Various embodiments for a three-dimensional in-the-air finger motion based user login framework for gesture interface are disclosed.

Abstract: A system and method for passive collection of atmospheric carbon dioxide is disclosed. The system includes a harvest chamber having a first opening and a sorbent regeneration system. The system also includes a capture body coupled to and movable by a support structure. The capture body includes a sorbent material and is movable by the support structure to be in a collection configuration wherein at least a portion of the capture body is in contact with a natural airflow outside the harvest chamber such that atmospheric carbon dioxide is captured by the sorbent material, and a release configuration wherein at least a portion of the capture body holding captured carbon dioxide is operated upon by the regeneration system inside the harvest chamber such that captured carbon dioxide is released to form an enriched gas.

Abstract: Provided herein are methods of estimating subject-specific parameters of growth dynamics of a cancer tumor in a subject having cancer. The methods can be used to personalize treatment protocols for a subject, stage the given disease in the subject, measure response to therapy, phenotype for patient selection to participate in drug trials, measure stability of an anatomical structure, or predict rate of change of the given disease. Also provided are methods of predicting growth dynamics of a cancer tumor, and computer systems and computer-implemented methods for estimating subject-specific parameters of growth dynamics of a cancer tumor in a subject having cancer.