Abstract: A microchannel 4 for transporting a specimen S using capillary phenomenon includes an analysis chamber 6 having a cross-sectional area larger than those of portions located in front of and behind the analysis chamber 6 in the direction of flow, an inflow opening 5 through which the specimen S flows into the analysis chamber 6, and a discharge portion 7 through which the specimen S is discharged from the analysis chamber 6. The discharge portion 7 includes a pair of discharge openings 71a and 71b located opposite to each other with respect to the inflow opening 5. With this structure, impairment of transport of the specimen S due to the presence of a residual air bubble is avoided.

Abstract: The present invention relates to an analysis system including a laser beam oscillator 60 that emits a laser beam for extracting bodily fluid from the skin, and one or more analysis tools 2 that are used for analyzing a specific ingredient in the bodily fluid and that have a through hole 23 through which the laser beam passes. The analysis tool 2 includes plural conductors 20, 21 layered in a state in which they are electrically insulated from each other. The analysis tool 2 further includes an insulation layer 26 interposed between adjacent conductors 20, 21, and insulation layers 27, 28 which covers an outer surface of at least one of two outermost conductors located on the outermost portions among the plural conductors 20, 21.

Abstract: An analyzing device which fits an analyzing instrument 2 thereinto for use and has a disposal mechanism 5 for disposing of the analyzing instrument 2 after completion of analysis, wherein the disposal mechanism 5 inputs a load in a direction different from a disposal direction D1 of the analyzing instrument 2 to dispose of the analyzing instrument 2. In the analyzing device 1 having a connector portion 4 having a terminal to be brought into contact with a terminal of the analyzing instrument 2, the disposal mechanism 4 is arranged below the connector portion 4.

Abstract: This invention is regard to an analysis device that analyze a specific component in bodily fluid extracted from the skin using an analysis tool. The analysis device comprise a laser beam oscillation section that emits a laser beam for extracting the bodily fluid from the skin, and a detection mechanism that detects whether or not the analysis tool exists at a target position. The analysis device is adapted to emit the laser beam from the laser beam oscillation section when the analysis tool is detected by the detection mechanism.

Abstract: A precursor of molecular probe for imaging of pancreatic islets is provided. A polypeptide represented by any one of the following formulae (1) to (4), or a polypeptide having a homology with the foregoing polypeptide. *-DLSK*?QMEEEAVRLFIEWLK*?NGGPSSGAPPPSK-NH2 (1) ?*-LSK*?QMEEEAVRLFIEWLK*?NGGPSSGAPPPSK-NH2 (2) ??*-SK*?QMEEEAVRLFIEWLK*?NGGPSSGAPPPSK-NH2 (3) ???*-K*?QMEEEAVRLFIEWLK*?NGGPSSGAPPPSK-NH2, (4) wherein *- indicates that an ?-amino group at an N-terminus is protected by a protecting group or modified with a modifying group having no electric charge; K* indicates that an amino group of a side chain of a lysine is protected by a protecting group; and —NH2 indicates that a carboxyl group at a C-terminus is amidated.

Abstract: A liquid droplet introducing tank 3A includes a tank body 31, which is formed by mutually opposing top surface 31a and bottom surface 31b, and a side surface 31c. The tank also includes an injection hole 32 that is opened in the top surface 31a. Liquid droplets Dr are injected from the injection hole 32. The center of the injection hole 32 is closer to the side surface 31c than the center of the top surface 31a. The liquid droplet introducing tank 3A enables liquid droplets to be suitably injected therein and is suitable for reducing size.

Abstract: The present invention provides a measurement reagent that is capable of suppressing nonspecific aggregation even when the amount of antibody to be carried is increased, and is capable of measuring in a wide measurement concentration range with high measurement sensitivity; an immunoturbidimetric assay using the same; and a method of producing thereof. A method of producing an insoluble carrier particle of the present invention is a method of producing an insoluble carrier particle carrying an antibody or an antigen on a particle surface thereof. The method includes a sensitization reaction processes in which the antibody or the antigen is brought into contact with the insoluble carrier particle in the presence of an amino acid with a charged polar side chain in a sensitization reaction solution. The insoluble carrier particles obtained by the producing method of the present invention show favorable dispersibility because nonspecific aggregation is suppressed. As can be seen from Examples 1-1 to 1-4 in FIG.

Abstract: The present invention relates to a method for forming a reagent layer in an analytical tool including a first step of holding a reagent-containing liquid onto a substrate, and a second step of drying the reagent-containing liquid. A liquid containing a tetraborate as a drying accelerator is used as the reagent-containing liquid. A content of a tetraborate in the reagent-containing liquid is, for example 1 g or more based on 100 mL of the reagent-containing liquid. The tetraborate is, for example, tetrasodium borate or tetrapotassium borate.

Abstract: The present invention provides a method for analyzing leukocytes, by which the leukocytes can be classified and measured stably with high accuracy even when a dilution ratio of a sample containing the leukocytes is low or a flow velocity during the analysis is slow, and an analysis reagent used for the analysis method. The analysis method of the present invention includes the steps of mixing a sample containing leukocytes and erythrocytes and an analysis reagent containing a surfactant that reacts with leukocytes; and measuring the leukocytes by passing a mixed solution of the sample and the analysis reagent through a fine through-hole, measuring a signal detected when the mixed solution passes through the fine through-hole, and classifying and counting the leukocytes in the sample. The analysis reagent further contains a nonionic surfactant, and the nonionic surfactant has a sugar residue as a hydrophilic region and an aliphatic chain as a hydrophobic region.

Abstract: A lancing member (2) is integrally provided with a cap (29) for covering a needle (21). Upon or after being attached to a holder (5) of a lancing device (A), the lancing member (2) is rotated relative to a cap (29) by a rotator (C). As a result, the boundary (28) between the cap (29) and the lancing member (2) is broken easily to expose the needle (21).

Abstract: The present invention relates to an analyzing instrument (1A) which includes a capillary (31), a fluid feed port (20) for introducing a sample liquid to the capillary (31), and a fluid feed promoter (6) for promoting the introduction of the sample liquid into the feed port (20). The capillary (31) of the analyzer (1A) may be formed on a substrate (2) for example. The fluid feed promoter (6) may include at lease one of a water-absorbing layer having a higher water-absorbing capacity than the substrate (2) and an adhesive layer having a greater adhesion to the skin than the substrate (2).

Abstract: The present invention provides a dry testing tool with which a metal in the various types of samples such as biological samples, food, and the like can be measured very easily, rapidly, high sensitively, and specifically by a simple colorimetric method and a method for measuring the metal. The dry testing tool of the present invention is a dry testing tool for measuring a metal in a sample, including a porous support and a chelate dye, wherein the chelate dye is bound to the porous support by a hydrophobic bond. The measuring method of the present invention is a method for measuring a metal in a sample, including the steps of: forming a composite of the chelate dye and the metal in the sample by supplying the sample to the porous support to which a chelate dye is bound by a hydrophobic bond; and detecting the metal in the sample using a developed color of the composite.

Abstract: A fluid agitation method is provided, whereby a swirling flow is generated in a trace amount of fluid, thereby agitating the fluid. The fluid agitation method includes introducing the fluid into an agitation chamber (3) including a wall having an uneven mass distribution, and applying oscillation (F) to the wall with frequencies varying in a predetermined frequency range. The uneven mass distribution of the wall is attained, for example, by arranging a plurality of thickened portions (11 to 18) of different thicknesses in a ring.

Abstract: A medical device includes a casing, a cover member that covers a portion on one-direction side of the same, and a sheet member interposed therebetween. The cover member includes on its periphery a hook part having a hook-like portion and a protrusion. The casing includes a latch part configured to engage with the hook part and a fitted portion for the protrusion to fit in. The sheet member includes an alignment part for aligning itself with the cover member. The cover member preferably has optical transparency. The casing preferably includes a recess shaped to fit with an outer shape of the cover member at a portion to be covered by the cover member.

Abstract: The present invention provides a stabilizer that can stabilize a salt of 10-(carboxymethylaminocarbonyn-3,7-bis(dimethylamino)phenothiazine or a derivative thereof even under the existence of moisture or under light irradiation. A compound described in at least one of (1) and (2) below is used as the stabilizer of the salt of 10-(carboxymethylaminocarbonyl)-3,7-bis(dimethylamino)phenothiazine or the derivative thereof.

Abstract: An albumin denaturing agent for digesting an albumin by a protease efficiently is provided. The albumin denaturing agent contains quaternary ammonium having a hydrocarbon group with a carbon number of 12 or more, or a salt of the quaternary ammonium. The albumin in a sample is digested by the protease in the presence of the albumin denaturing agent, a glycated part of the thus obtained albumin digestion product and a FAOD effect a reaction, and a redox reaction between the glycated part and the FAOD is measured, thereby determining a ratio (GA (%)) of the glycated albumin of the glycated albumin with respect to the albumin.

Abstract: The present invention provides a liquid delivery control method for delivering a liquid 8 by generating, in a microchannel 3 in which the liquid 8 is present, a differential pressure with respect to the liquid 8 by using a pump 6. The microchannel 3 is provided with a pressure loss varying portion 31 in which pressure loss changes in the direction of flow. The leading end 8a of the liquid 8 is judged to have reached the pressure loss varying portion 31 by detecting a change in pressure between the liquid 8 and the pump 6. With this arrangement, the location of the leading end of the liquid 8 can be properly detected without causing the structure that forms the microchannel 3 to become complex.

Abstract: A sample analysis device is provided in which a target component to be analyzed is prevented from being contaminated by a sample itself, which can be formed in an appropriate size, and which has excellent operability. In a sample analysis device 1 in which a sample is to be held in a porous sheet 13, supporting films 11 and 12 are stuck on front and rear faces of the porous sheet 13, respectively, and a sample supply hole 14 is formed in a part of the supporting films.

Abstract: The present invention relates to a technique for analyzing the concentration of a specific component in a sample liquid, such as a method for analyzing a sample. The analyzing method includes a first detection step for irradiating light from a light source (50) onto a reaction system to detect a response from the reaction system (56) as a first detection result. The reaction system contains a sample liquid and a reagent. The method also includes a second detection step for irradiating light onto a reference board (54) to detect a response from the reference board as a second detection result. The response from the reference board under light irradiation is dependent on wavelength. The method further includes a calculation step for calculating the concentration of the specific component in the sample liquid based on the first and second detection results.

Abstract: The present invention relates to a test piece supplying device (1) comprising a container (4) for containing a plurality of test pieces, and also includes a movable body (3) moving relative to the container (4) with the test piece accommodated in a recess (30) so as to take the test piece out of the container (4). The container (4) includes a sweeping portion (41) for interfering with the test pieces, in the container (4), located above the test piece accommodated in the recess (30), when the movable body (3) moves relative to the container (4). When a warped test piece accommodated in the recess (30) is moved relative to the container (4), the interfering portion (41) flattens the test strip to be accommodated in the recess (30) so that the test piece is easily taken out of the container (4).