Abstract: A lancing device according to the present invention includes: a housing; a moving body movable relatively to the housing for forward movement of a needle; a driving mechanism for forward movement of the moving body; a hollow pressing portion at a front end of the housing for contact with a part where a puncture is to be made; and a pump mechanism capable of causing a vacuum to act inside the pressing portion. The pump mechanism is capable of adjusting the vacuum. The pump mechanism includes for example: a moving portion capable of reciprocating in a first direction and a second direction away from the first direction. Preferably, the adjustment of the vacuum is made by changing the number of reciprocations of the moving part in the first and the second directions.

Abstract: A fine channel flowmeter A1 is provided for measuring the amount of a blood sample DS through a channel 10. The flowmeter includes at least two electrode groups 62Aa, 62Ab each including a pair of electrodes 62a, 62b, and a conduction detector 7 for detecting electrical conduction between the paired electrodes 62a, 62b included in each of the electrode groups 62Aa, 62Ab. Each of the electrodes 62a, 62b is exposed in the channel 10 at least partially, and the electrode groups 62Aa, 62Ab are spaced from each other in the flow direction of the channel 10.

Abstract: A process for analyzing a sample by a capillary electrophoresis method is provided that allows the apparatus to be reduced in size, allows a high analytical precision to be obtained, and can be carried out easily. The analytical process of the present invention is a process for analyzing a sample by a capillary electrophoresis method. The process includes a step of preparing a capillary channel to be used for the capillary electrophoresis method and a step of electrophoresing a complex of a sample and an anionic group-containing compound that are bonded together, in the capillary channel, wherein the capillary channel includes an A layer that is coated on an inner wall thereof and a B layer that is coated on the A layer.

Abstract: A method of measuring HbA1c is provided that, even with a whole blood sample after storage, measurement accuracy substantially equal to a whole blood sample right after collection can be maintained. Whole blood is stored in a presence of a glycolytic inhibitor and protease is added to the stored whole blood sample to cleave hemoglobin in the whole blood sample. Then a glycated part of a hemoglobin fragment thereby obtained is treated with fructosyl amine oxidase. Thereafter, a glycation degree of HbA1c is determined by measuring a redox reaction between the glycated part and the fructosyl amine oxidase. Further, instead of storage of the whole blood in a presence of the glycolytic inhibitor, a strong electrolyte substance such as KCl, K2SO4, KNO, NaCl, Na2SO4, NaNO, MgCl2, MgSO4, Mg(NO)2, etc. is added to the whole blood after storage and a protease treatment is performed in a presence of the strong electrolyte substance.

Abstract: A new mutant gene related to the onset of CMPD, particularly, the new mutant gene related to the onset of CMPD in patients who develop CMPD despite of JAK2V617F-negative, and an evaluation method for evaluating CMPD are provided. By detecting the following mutation in a JAK2 gene or an EPOR gene in a biological sample of human origin, the possibility of CMPD is evaluated. (a) a mutation from G at the 2116th position to A in a base sequence of SEQ ID NO: 1, (b) a deletion of a nucleotide residue from the 2121st to 2126th position in a base sequence of SEQ ID NO: 1, (c) a mutation from C at the 1641st position to G in a base sequence of SEQ ID NO: 4.

Abstract: The present invention provides a sample measuring device capable of allowing not only one but more than one kind of samples to react with a reagent, and enhancing a reliability in photometric analysis accuracy by reliably mixing and agitating the sample and the reagent prior to the photometric analysis. The device includes a reagent melting/mixing means, a sample supply chamber positioned on the upstream side of, and communicating with, the reagent melting/mixing means when the sample is allowed to flow into the reagent melting/mixing means, and at least one measuring chamber positioned on the downstream side of, and communicating with, the reagent melting/mixing means, wherein the sample supply chamber, the reagent melting/mixing means, and the measuring chamber are arranged sequentially from the upstream to the downstream directions of the flow passage, with the sample supply chamber positioned on the upstream side with respect to the sample flow by a sample moving means.

Abstract: A test apparatus is disclosed for measuring a component. The test apparatus maintains the amount of a specimen to be used for a reaction with a reagent at a constant value by allowing all of a fluid specimen to be measured and thus improves the accuracy and reproducibility of a test. The test apparatus includes a solution storage unit capable of holding a solution beforehand or allowing a solution to be filled therein, a capillary having a first end part and a second end part for storing the fluid specimen, and a test piece for measuring the component to be measured in the specimen. The solution storage unit and the second end part of the capillary are communicable with each other, and the first end part of the capillary is placed so as to be in contact with the test piece.

Abstract: In a medical device that measures a condition of a living body, a recess is formed on the exterior (first and second surfaces) of its casing. An attachment member is attached to the inside of the recess. In the case where a display screen that displays a measurement result is provided on the casing, it is preferable that the first and second surfaces are adjacent to a third surface on which the display screen is provided. Preferably, the attachment member includes an adhesive material layer, a print layer, and an anti-slip layer that is formed of at least one of a resin material and a rubber material, and the adhesive material layer, the print layer, and the anti-slip layer are stacked in sequence.

Abstract: The present invention is directed to the described capillary electrophoresis apparatus and methods of using such apparatus for separating and analyzing components of a sample.

Abstract: A medical device measures a condition of a living body. The medical device includes a main body containing a measuring device inside, and a sheet member. The sheet member displays information on a user on one principal surface, with the other principal surface being attached to an outer surface of the main body. The sheet member may include a sheet-like base, a protective layer formed on one principal surface of the base, and an adhesive material layer formed on the other principal surface of the base. At this time, it is preferable that the protective layer is formed of a material having optical transparency, and that the information on the user is displayed on the one principal surface of the base.

Abstract: A measurement device A includes a display section 10 capable of displaying measurement data obtained by measurement means 12, 13, 14a, a clock function section 16, an event time setting means 14b, 15 capable of setting the time of an event, and an elapsed time display processing means 14c that starts measurement of the elapsed time from the time of the event to the current time when the time of the event is set by the event time setting means and causes the display section 10 to display the elapsed time. With this arrangement, the user does not need to perform a troublesome task of calculating the elapsed time, and the measurement of a sample in a proper period of time after the event is promoted.

Abstract: The present invention relates to a method for measuring the concentration of a particular component in a blood sample containing blood cells based on a variable correlated with the concentration of the particular component. In the present invention, a concentration (S) in blood plasma obtained by removing blood cell components from the blood sample, a concentration (DI) in the blood sample computed by a differential method and a concentration (EP) in the blood sample computed by an equilibrium point method are expressed by a relational expression which is unrelated to the proportion of the blood cell components in the blood sample, and the concentration of the particular component is computed by using the relational expression.

Abstract: The invention relates to an analyzing apparatus including an installation portion having an insertion port 43 and provided for installing an analytical tool 20, a light measuring mechanism 22 and 23 irradiating light to the analytical tool 20 and receiving the light making progress from the analytical tool 20 for analyzing a sample in accordance with an optical method, and a light shielding means 63 for limiting an incoming radiation of an external light from the insertion port 43. The light shielding means 63 is structured such as to limit the incoming radiation of the external light via the insertion port 43 after starting the insertion of the analytical tool 20 to the installation portion before the light measurement of the analytical tool 20 is finished in the light measuring mechanism 22 and 23.

Abstract: In order to provide a liquid crystal display device which can detect a defective indication due to short circuit which occurs between a common electrode and a counter electrode by a conductive impurity enters into a liquid crystal display panel, and an analysis device including the same, a blood glucose meter includes a display section and a microcomputer. For performing an inspection for a defective indication on a liquid crystal display panel of the display section, the microcomputer uses ports as input/output ports for a defective indication inspection. The microcomputer detects whether an inspection signal sent from the port can be received at the other port or not to perform the inspection for a defective indication.

Abstract: In order to provide a liquid crystal display device which can detect a defective indication due to short circuit which occurs between a common electrode and a counter electrode by a conductive impurity enters into a liquid crystal display panel, and an analysis device including the same, a blood glucose meter includes a display section and a microcomputer. For performing an inspection for a defective indication on a liquid crystal display panel of the display section, the microcomputer uses ports as input/output ports for a defective indication inspection. The microcomputer detects whether an inspection signal sent from the port can be received at the other port or not to perform the inspection for a defective indication.

Abstract: An electrophoresis chip that can be small and simple and that can analyze a sample with high accuracy is provided. The electrophoresis chip includes an upper substrate 4, a lower substrate 1, an introduction reservoir 2a, a recovery reservoir 2b and a capillary channel for sample analysis 3x. The introduction reservoir 2a and the recovery reservoir 2b are formed in the lower substrate 1. The introduction reservoir 2a and the recovery reservoir 2b are in communication with each other via the capillary channel for sample analysis 3x. The introduction reservoir 2a receives a sample to be measured. The sample is electrophoretically introduced directly into the capillary channel for sample analysis 3x by creating a potential difference between the introduction reservoir 2a and the recovery reservoir 2b, and is also analyzed in the capillary channel for sample analysis 3x during the separation of the sample while the sample is being continuously supplied.

Abstract: A process for producing glucose dehydrogenases. This process comprises transferring a DNA containing a sequence represented by SEQ ID NO:1 which encodes an ? subunit having a glucose dehydrogenase activity and a ? subunit being an electron transfer protein into a microorganism belonging to the genus Pseudomonas to thereby construct a transformant, and culturing this transformant so as to allow the production of a first glucose dehydrogenase containing the above-described ? subunit and a second glucose dehydrogenase free from the ? subunit. The ? subunit as described above has a molecular weight of about 60 kDa measured by, for example, SDS-polyacrylamide gel electrophoresis under reducing conditions, while the ? subunit as described above has a molecular weight of about 43 kDa measured by, for example, SDS-polyacrylamide gel electrophoresis under reducing conditions.

Abstract: In order to provide a high-performance electrophoresis chip and an electrophoresis unit having the same that can restrain the diffusion of sample at an intersection between the electrophoresis groove and the sample introduction groove and prevent decrease in contrast and decrease in resolution, an electrophoresis chip is provided with a sample introduction groove, an electrophoresis groove, and a through hole. The sample introduction groove, the electrophoresis groove, and the through hole are formed on different substrates. In the electrophoresis chip, by combining the substrates, the sample introduction groove and the electrophoresis groove are located in different planes.

Abstract: A pellet used for spectrometry is manufactured by, for example, mixing polyethylene powder having an average particle size not greater than 35 ?m with powder of an analysis target, and compressing the mixture. A sample pellet (B) prepared by compacting only polyethylene powder having an average particle size not grater than 35 ?m exhibits a high transmittance in the wave number range of 10-340 cm?1. In spectrometry using a pellet of the present invention, spectrum waveform of the analysis target material at a range of wave number 140-250 cm?1 is measured.

Abstract: In order to provide a high-performance electrophoresis chip and an electrophoresis unit having the same that can restrain the diffusion of sample at an intersection between the electrophoresis groove and the sample introduction groove and prevent decrease in contrast and decrease in resolution, an electrophoresis chip is provided with a sample introduction groove, an electrophoresis groove, and a through hole. The sample introduction groove, the electrophoresis groove, and the through hole are formed on different substrates. In the electrophoresis chip, by combining the substrates, the sample introduction groove and the electrophoresis groove are located in different planes.