Patents Assigned to Arrow International, Inc.
  • Patent number: 10368837
    Abstract: In an aspect, embodiments of the invention relate to the effective and accurate placement of intravascular devices such as central venous catheters, in particular such as peripherally inserted central catheters or PICC. One aspect of the present invention relates to vascular access. It describes devices and methods for imaging guided vascular access and more effective sterile packaging and handling of such devices. A second aspect of the present invention relates to the guidance, positioning and placement confirmation of intravascular devices without the help of X-ray imaging. A third aspect of the present invention relates to devices and methods for the skin securement of intravascular devices and post-placement verification of location of such devices. A forth aspect of the present invention relates to improvement of the workflow required for the placement of intravascular devices.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: August 6, 2019
    Assignee: ARROW INTERNATIONAL, INC.
    Inventors: Sorin Grunwald, Fiona Maria Sander, Wilfred J. Samson, Bradley Hill
  • Patent number: 10368830
    Abstract: A method of navigating and positioning an endovascular device in a vasculature is disclosed. Initially, a system including an endovascular device and at least one transducer is inserted into the lumen of a patient. An acoustic signal is then transmitted within the lumen. A reflected signal is pre-processed to extract one or more acoustic features. The one or more acoustic features are processed using a computer readable set of rules to produce an output related to guidance of the instrument within a blood vessel or a position of the instrument within the blood vessel.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: August 6, 2019
    Assignee: ARROW INTERNATIONAL INC.
    Inventors: Wenkang Qi, Bradley Hill
  • Patent number: 10335240
    Abstract: The endovascular navigation system includes an elongate flexible member configured to access the venous vasculature of a patient, a sensor disposed at a distal end of the elongate flexible member and configured to sense a physiological characteristic of the venous vasculature, a processor and an output device. The processor is configured to receive and process the physiological characteristic of the venous vasculature, and to determine that the position of the distal end of the elongate flexible member is within a predetermined structure within the venous vasculature. The output device is configured to display a visual indication that the distal end of the elongate flexible member is within the predetermined structure within the venous vasculature, where the visual indication is different from the physiological characteristic of the venous vasculature of the patient.
    Type: Grant
    Filed: November 29, 2015
    Date of Patent: July 2, 2019
    Assignee: ARROW INTERNATIONAL, INC.
    Inventors: Sorin Grunwald, Bradley Hill
  • Patent number: 10321890
    Abstract: An endovascular navigation system and method are disclosed. The endovascular navigation system includes an elongate flexible member, a endovascular electrogram lead disposed at a distal end of the elongate flexible member and configured to sense an endovascular electrogram signal, a processor and an output device. The processor is configured to receive the endovascular electrogram signal, to determine a peak amplitude of a P-wave in the endovascular electrogram signal, and to determine that the position of the distal end of the elongate flexible member is within a predetermined structure within the venous vasculature of the patient. The output device is configured to display a visual indication that the distal end of the elongate flexible member is within the predetermined structure within the venous vasculature of the patient, where the visual indication is different from the endovascular electrogram signal of the venous vasculature of the patient.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: June 18, 2019
    Assignee: ARROW INTERNATIONAL, INC.
    Inventors: Sorin Grunwald, Fiona M. Sander, Wilfred J. Samson, Bradley Hill, E. Tina Cheng
  • Patent number: 10271820
    Abstract: An endovascular navigation system and method are disclosed. The endovascular navigation system includes an elongate flexible member, a endovascular electrogram lead disposed at a distal end of the elongate flexible member and configured to sense an endovascular electrogram signal, a processor and an output device. The processor is configured to receive the endovascular electrogram signal, to determine a peak amplitude of a P-wave in the endovascular electrogram signal, and to determine that the position of the distal end of the elongate flexible member is within a predetermined structure within the venous vasculature of the patient. The output device is configured to display a visual indication that the distal end of the elongate flexible member is within the predetermined structure within the venous vasculature of the patient, where the visual indication is different from the endovascular electrogram signal of the venous vasculature of the patient.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: April 30, 2019
    Assignee: ARROW INTERNATIONAL, INC.
    Inventors: Sorin Grunwald, Fiona M. Sander, Wilfred J. Samson, Bradley Hill, E. Tina Cheng
  • Publication number: 20190010268
    Abstract: A photoactivatable fouling-resistant copolymer composed of a photoactivatable monomer and a hydrophilic monomer is disclosed. The photoactivatable monomer includes an aryl ketone derivative having one or more polar groups or alkyl groups.
    Type: Application
    Filed: August 12, 2016
    Publication date: January 10, 2019
    Applicant: ARROW INTERNATIONAL, INC.
    Inventors: ZHENG ZHANG, FANNI TOROK, JUN LI, MICHAEL BOUCHARD, JOHN VICTOR
  • Patent number: 10117974
    Abstract: A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cm2 in a fibrinogen binding assay in which the modified surface is incubated for 60 minutes at 37° C. in 70 ?g/mL fibrinogen derived from human plasma containing 1.4 ?g/mL I-125 radiolabeled fibrinogen.
    Type: Grant
    Filed: November 3, 2014
    Date of Patent: November 6, 2018
    Assignee: ARROW INTERNATIONAL, INC.
    Inventors: Jun Li, Zheng Zhang, Chad C. Huval, Michael A. Bouchard, Christopher R. Loose, Arthur J. Coury
  • Patent number: 10016532
    Abstract: The present invention generally relates to articles of manufacture, such as medical devices, having a non-fouling surface comprising a grafted polymer material. The surface resists the adhesion of biological material.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: July 10, 2018
    Assignee: ARROW INTERNATIONAL, INC.
    Inventors: Zheng Zhang, Jun Li, Chad C. Huval, Michael A. Bouchard, Arthur J. Coury, Christopher R. Loose
  • Patent number: 9895469
    Abstract: Processes are described herein for preparing medical devices and other articles having a low-fouling surface on a substrate comprising a polymeric surface. The polymeric surface material may possess a range of polymeric backbones and substituents while providing the articles with a highly efficient, biocompatible, and non-fouling surface. The processes involve coating the substrate to conceal or reduce flaws on or in the surface of the medical device or other article substrate, and thereafter forming a grafted polymer layer on the treated substrate surface.
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: February 20, 2018
    Assignee: ARROW INTERNATIONAL, INC.
    Inventors: Karen A. Schultz, Zheng Zhang, Chad C. Huval, Michael A. Bouchard, Christopher R. Loose
  • Patent number: 9795762
    Abstract: Catheters and a method of preparation thereof, the catheter comprising a catheter body, a juncture hub, extension lines and connectors, the catheter body having a proximal end, a distal end, an exterior surface, a tip region having a length of 10 cm measured from the distal end of the catheter body, and at least two lumen, each of the catheter body lumen having a proximal end, a distal end, a Lumen Aspect Ratio of at least 3:1, and an intraluminal surface, the distal ends of the at least two catheter body lumen being (i) non-coterminus or (ii) laser-cut, the exterior surface of the catheter body in the tip region or the intraluminal surface of the two catheter body lumen comprising a hydrophilic polymer layer having an Average Dry Thickness of at least about 50 nanometers.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: October 24, 2017
    Assignee: ARROW INTERNATIONAL, INC.
    Inventors: Michael Bouchard, Zheng Zhang, Jun Li, Matt Skinner, Laurence Roth, Douglas Weaver, Eric W. Marchese, Robert Reed, Chad Huval, Christopher R. Loose
  • Patent number: 9694114
    Abstract: Catheters and a method of preparation thereof comprising a catheter body and at least one connector. The catheter body has an exterior surface and at least one lumen having an aspect ratio of at least 3:1 and an intraluminal surface comprising a hydrophilic polymer layer thereon, the hydrophilic polymer layer has an average dry thickness of at least about 50 nanometers, wherein the catheter body comprises one or more permeabilization agents and one or more antimicrobial agents.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: July 4, 2017
    Assignee: ARROW INTERNATIONAL, INC.
    Inventors: David Lucchino, Christopher R. Loose
  • Patent number: 9399367
    Abstract: A dual chamber container includes an inner hollow body containing a marker fluid which is adapted to be dispensed. The inner hollow body is at least partially surrounded by an outer hollow body containing a decorative fluid which is retained in the container as the marker fluid is dispensed.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: July 26, 2016
    Assignee: Arrow International, Inc.
    Inventors: Jim A. Schaffnit, Gary E. Johnston, Shannon K. Gallagher
  • Patent number: 9358326
    Abstract: Substrates, optionally coated with an undercoating, having grafted thereto one or more non-fouling materials are described herein. The non-fouling, polymeric material can be grafted to a variety of functionalized substrate materials, particularly polymeric substrates and/or polymeric undercoatings immobilized on a substrate. The compositions described herein are highly resistant protein absorption, particularly in complex media and retain a high degree of non-fouling activity over long periods of time. The compositions described herein may also demonstrate antimicrobial and/or anti-thrombogenic activity. The non-fouling material can be grafted to a functionalized substrate, or optionally from an undercoating on the substrate, preferably without significantly affecting the mechanical and/or physical properties of the substrate material.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: June 7, 2016
    Assignee: ARROW INTERNATIONAL, INC.
    Inventors: Zheng Zhang, Chad Huval, William Shannan O'Shaughnessey, Michael Hencke, Trevor Squier, Jun Li, Michael Bouchard, Christopher R. Loose
  • Publication number: 20150050066
    Abstract: A dual chamber container includes an inner hollow body containing a marker fluid which is adapted to be dispensed. The inner hollow body is at least partially surrounded by an outer hollow body containing a decorative fluid which is retained in the container as the marker fluid is dispensed.
    Type: Application
    Filed: August 12, 2014
    Publication date: February 19, 2015
    Applicant: ARROW INTERNATIONAL, INC.
    Inventors: Jim A. Schaffnit, Gary E. Johnston, Shannon K. Gallagher
  • Patent number: 8895047
    Abstract: Implantable catheters are provided which comprise an antimicrobial agent incorporated in a coating or bulk distributed, in combination with a fibrinolytic agent incorporated in a top coating.
    Type: Grant
    Filed: May 21, 2008
    Date of Patent: November 25, 2014
    Assignee: Arrow International, Inc.
    Inventors: Nisha Gupta, Joel Rosenblatt, Daniel J. Spangler
  • Publication number: 20140114284
    Abstract: An embodiment in accordance with the present invention provides an integrated syringe-device which can store a volume of fluid for infusion, can connect via an air-tight connector to another device (such as a luer connector), can flush fluid through the connector into the other device, and can deliver a cap that forms an air-tight closure to the device connector.
    Type: Application
    Filed: December 31, 2013
    Publication date: April 24, 2014
    Applicant: ARROW INTERNATIONAL, INC.
    Inventors: David T. ROWE, Rodney W. DENLINGER, Joel S. ROSENBLATT, Nisha GUPTA, Joseph A. RUNKLE, Jeffrey M. VITULLO, Philip D. SCHMIDT, William J. VOJTASEK
  • Patent number: 8617120
    Abstract: An embodiment in accordance with the present invention provides an integrated syringe-device which can store a volume of fluid for infusion, can connect via an air-tight connector to another device (such as a luer connector), can flush fluid through the connector into the other device, and can deliver a cap that forms an air-tight closure to the device connector.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: December 31, 2013
    Assignee: Arrow International, Inc.
    Inventors: David T. Rowe, Rodney W. Denlinger, Joel S. Rosenblatt, Nisha Gupta, Joseph A. Runkle, Jeffrey M. Vitullo, Philip D. Schmidt, William J. Vojtasek
  • Patent number: 8611993
    Abstract: A stimulating needle and catheter system, including components, is provided such that the position of the stimulating needle or the stimulating catheter may be identified after insertion into the body of a patient by electrically stimulating and thus locating a specific nerve. Use of the needle and catheter system is eased by providing the system to the medical practitioner in a unitary structure. That is, the needle and catheter are connected by a catheter lock. The catheter lock is attached to the hub of the needle and can be actuated to either firmly grip the catheter or allow the catheter to move axially with respect to the lock and needle assembly. Thus, supplying the catheter to the practitioner already locked into the catheter lock allows the practitioner to insert the needle into the patient and, when ready, release the catheter for disposal through the needle into the patient. This and other disclosed features allow the medical practitioner to focus attention on the medical procedure.
    Type: Grant
    Filed: March 8, 2005
    Date of Patent: December 17, 2013
    Assignee: Arrow International, Inc.
    Inventors: Jeffrey M. Vitullo, Fred Hafer, Mark J. Spinka, Richard L. Harding
  • Patent number: 8577943
    Abstract: A method and apparatus for generating a plurality of unique configurations of indicia is provided. A first set of indicia is provided, including a plurality of first groups of indicia. Then a second set of indicia is provided that has a plurality of second groups of indicia. The first set of indicia is then combined with the second set of indicia in a pairwise fashion, wherein a number of the first groups of indicia is relatively prime in relation to an number of the second groups of indicia.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: November 5, 2013
    Assignee: Arrow International, Inc.
    Inventor: Gregory T. Pollock
  • Patent number: 8204582
    Abstract: The present invention provides methods and apparatus for generating a trigger from the R wave of an electrocardiogram (ECG) waveform using a threshold that adapts to the slope of the R wave while still within the leading edge of the R wave.
    Type: Grant
    Filed: December 6, 2006
    Date of Patent: June 19, 2012
    Assignee: Arrow International, Inc.
    Inventors: George N. Zantos, Patricia Hanlon-Pena