Abstract: Methods and devices described herein facilitate improved treatment of body organs.

Abstract: A pulsed field ablation effector comprising: (a) an electrode including an electrode surface for delivering electric current to anatomical tissue, and a deformable insulator selectively covering the electrode surface, the deformable insulator configured to deform when contacted by the anatomical tissue to expose the electrode surface. Also disclosed are methods and devices for carrying out electroporation and other forms of ablation concomitant with electroporation.

Abstract: A cryogenic probe, comprising: (a) a handle, (b) a shaft disposed distally on the handle, the shaft comprising a generally rigid proximal portion and a generally malleable distal portion, and (c) an active tip disposed distally on the shaft, where the shaft comprises a supply conduit configured to supply a cryogenic fluid to the active tip, an exhaust conduit configured to exhaust spent cryogenic fluid from the active tip, and a vacuum insulating layer disposed around the supply conduit and the exhaust conduit.

Abstract: Devices, systems, and methods for therapeutically treating tissue. The devices and methods are suitable for minimally invasive surgery or open surgical procedures. More particularly, methods and devices described herein permit treating large areas of tissue with a therapeutic device. In some variations, the method and devices allow for large area treatment without having to reposition the device. The methods and devices described herein discuss the treatment of cardiac tissue for purposes of illustration.

Abstract: Devices, systems, and methods for therapeutically treating tissue. The devices and methods are suitable for minimally invasive surgery or open surgical procedures. More particularly, methods and devices described herein permit accessing and/or treating areas of tissue with a therapeutic device.

Abstract: Methods and devices described herein facilitate diaphragm entry for posterior access of body organs.

Abstract: Tissue treatment systems for cardiac surgical procedures can include an ablation and monitoring assembly having a first ablation element, a second ablation element, and a monitoring mechanism. Treatment methods may involve placing an ablation and monitoring assembly of the tissue treatment system at a patient tissue treatment site, applying a first ablative energy to a first tissue location via the first ablation element and a second ablative energy to a second tissue location via the second ablation element, monitoring a condition of the first tissue location with the monitoring mechanism, and modulating application of the first ablative energy to the first tissue location in response to the condition of the first tissue location while maintaining application of the second ablative energy to the second tissue location. Embodiments also include techniques for assessing a conduction delay across a lesion that involve evaluating local activation rates on various sides of a lesion.

Abstract: Ablation systems, components thereof, and related methods are disclosed. An example ablation system may include a first ablation component including a first ablation component end effector configured to be positioned on a first side of a target tissue and a second ablation component including a second ablation component end effector configured to be positioned on a second side of the target tissue. The first ablation component may include a first ablation component permanent magnet that is translationally repositionable between an engaged configuration and a disengaged configuration. The second ablation component may include a second ablation component permanent magnet that is freely rotatable and is configured to rotatably self-orient into a magnetically attractive orientation with the first ablation component permanent magnet.

Abstract: Surgical instruments and devices for creating surgical working spaces and related methods are disclosed. An example surgical spacemaking device may include surgical spacemaking device an elongated connecting portion and an expandable spacemaking portion disposed distally on the connecting portion. The spacemaking portion may include an expandable lateral base portion. an expandable first vertical lateral portion configured to extend generally orthogonally from the lateral base portion, and an expandable second vertical lateral portion configured to extend generally orthogonally from the lateral base portion.

Abstract: Exemplary scope systems and methods involve a cannula assembly, a sheath assembly, and a tubing set. A cannula assembly, which may be a non-magnetic scope cap assembly, can include a cannula body, a proximal housing having a strap, an optical window, and a luer for suction or flushing. A cannula body may include a first lumen or scope channel for receiving a visualization device such as an endoscope or laparoscope, a distal end having suction or flushing flush apertures, and a second lumen for providing fluid communication between the apertures and the luer. Exemplary magnetic introducer systems and methods involve a cannula assembly, a sheath assembly, a tubing set. In some cases, the cannula assembly of a magnetic introducer system can be a magnetic scope cap assembly. In addition to cannula and sheath assemblies, magnetic introducer systems can include a magnetic introducer tubing assembly and a stylet assembly.

Abstract: Medical devices and instruments, particularly pericardial access systems and devices and related methods are disclosed. Some example pericardial access devices may include a distally located, expandable skirt configured to engage the pericardium. When extended, the skirt may be wider than the tubular body of the device. Some example pericardial access devices may include an at least partially transparent, repositionable tip.

Abstract: An occlusion clip comprising: (a) a spring; (b) a first runner including a first open top and a first open end adjacent the first open top, the first runner including a first interior camming surface partially delineating a first interior cavity that is open by way of the first open top and the first open end; (c) a second runner including a second open top and a second open end adjacent the second open top, the second runner including a second interior camming surface partially delineating a second interior cavity that is open by way of the second open top and the second open end, where the spring is configured to be coupled to the first runner and the second runner, where the first interior cavity is configured to receive a first portion of the spring, where the second interior cavity is configured to receive a second portion of the spring, where the first camming surface is configured to engage a first cam of the spring, and where the second camming surface is configured to engage a second cam of the sprin

Abstract: Devices, systems, and methods for therapeutically treating tissue. The devices and methods are suitable for minimally invasive surgery or open surgical procedures. More particularly, methods and devices described herein permit accessing and/or treating areas of tissue with a therapeutic device.

Abstract: A medical instrument comprising: (a) a first joint comprising a first member and a second member, the first member configured to be repositionable with respect to the second member in a first degree of freedom; (b) a second joint operatively coupled to the first joint, the second joint comprising a third member and a fourth member, the third member configured to be repositionable with respect to the fourth member in a second degree of freedom; (c) a pair of repositionable jaws operatively coupled to the first joint and the second joint; (d) an open-ended occlusion clip detachably mounted to the pair of repositionable jaws; and, (e) a controller operatively coupled to the first joint, the second joint, and the pair of repositionable jaws, the controller including a first control configured to direct repositioning of at least one of the first member and the second member, and a second control configured to direct repositioning of at least one of the third member and the fourth member, and a third control config

Abstract: Described here are devices for closing one or more tissues, and handles for controlling these devices. Generally, the devices described here comprise a snare loop assembly, wherein the snare loop assembly comprises a snare loop and a suture loop, and a handle for controlling the snare loop assembly. In some variations the snare loop assembly may comprise a retention member that may releasably connect the suture loop to the snare loop. In other variations the devices comprise one or more force-reducing suture locks to help prevent the suture loop from inadvertently disengaging from the snare loop assembly. In still other variations, the excess-suture management features. The handles described here may be configured to remove excess suture from a suture loop, and may also be configured to release the suture loop from the snare loop assembly.

Abstract: Medical devices and related methods, and, more specifically, cryogenic surgical systems and related methods are disclosed. Some example cryogenic surgical systems may include a cryosurgical control unit configured to cool a cryosurgical probe to a temperature colder than a temperature at which flow of cryogenic fluid to the probe is stopped. Some example tank level indicating systems may utilize the pressure of the fluid in the tank and a temperature of the exterior wall of the tank to indicate liquid level.

Abstract: Delivery devices configured to deliver therapeutic and visualization devices to a surgical site are disclosed. An example delivery device may include a proximally disposed handle; a shaft extending distally from the handle, the shaft including a therapeutic device lumen configured to deliver a working end of a therapeutic device therethrough, a first portion of the shaft being steerable; and a space-making element disposed proximate a distal end portion of the shaft and configured to separate biological tissues to create or expand a working space. At least a portion of the space-making element may be reconfigurable between a retracted configuration and an expanded configuration.

Abstract: Embodiments of the present invention encompass systems and methods to prevent complications from atrial fibrillation by preventing or reducing the likelihood of blood flow out of the left atrial appendage, to eliminate a possible source of aberrant electrical circuits, or both. Accordingly, techniques are provided for delivering ligature loops or closure means to the left atrial appendage, and to other anatomical structures of a patient which may be desirable in other surgical procedures.

Abstract: Methods and devices described herein facilitate improved access of locations within the body.

Abstract: A laparoscopic device comprising: (a) a housing operatively coupled to a first control and a second control; (b) an end effector operatively coupled to the first control, the end effector comprising a first component and a second component selectively repositionable with respect to one another within an X-Y plane, the end effector also including a third component selectively repositionable with respect to the second component within an Y-Z plane; (c) a laparoscopic conduit extending between the housing and the end effector; and, (d) an occlusion clip deployment device operatively coupled to the end effector and the second control.