Abstract: A tissue treatment system configured to ablate a tissue, the system comprising: (a) a clamp assembly comprising a first jaw mechanism and a second jaw mechanism configured to receive and compress a tissue therebetween; (b) a first electrode disposed on the first jaw mechanism and configured to contact the tissue; and (c) a second electrode disposed on the second jaw mechanism and configured to contact the tissue, where the first electrode and the second electrode are configured so that at least one of an ablation energy output of the first electrode and an ablation energy output of the second electrode is automatically adjusted to accommodate variable tissue thicknesses between the first electrode and the second electrode.

Abstract: Methods of performing surgical operations and associated devices are disclosed. An example method may include locating a first position on a first surface of a biological tissue; locating a second position on a second opposing surface of the biological tissue, the second position corresponding to the first position; and marking the second position on the second surface. The second surface may be generally opposite the first surface. An example method may include, after marking the second position, performing a therapeutic procedure on the biological tissue in the vicinity of the second position.

Abstract: Systems and methods for forming a lesion on an endocardial tissue of a patient's heart involve placing an ablation assembly inside of the heart and adjacent to the endocardial tissue, and placing a guiding assembly outside of the heart. An ablation assembly includes an ablation element and a first attraction element, and a guiding assembly includes a second attraction element. First and second attraction elements can be attracted via magnetism. Techniques involve forming an ablation on the cardiac tissue of a patient's heart with an ablation element of the ablation assembly. Optionally, techniques may include moving the second attraction element of the guiding assembly relative to the patient's heart, so as to effect a corresponding movement of the ablation element of the ablation assembly.

Abstract: Methods for using a surgical device integrating a suction mechanism with a coagulation mechanism for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue with at least one diagnostic element coupled to an energy transfer element of the device. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source and a fluid source to passively transport fluid along the contacted soft tissue surface in order to push the maximum temperature deeper into tissue.

Abstract: A medical instrument comprising: (A) a first joint comprising a first member and a second member, the first member configured to be repositionable with respect to the second member in an X-Y plane; (B) a second joint operatively coupled to the first joint, the second joint comprising a third member and a fourth member, the third member configured to be repositionable with respect to the fourth member in a Y-Z plane perpendicular to the X-Y plane; and, (C) a controller operatively coupled to the first joint and the second joint, the controller including a first control configured to direct repositioning of at least one of the first member and the second member, and a second control configured to direct repositioning of at least one of the third member and the fourth member.

Abstract: Disclosed are devices for pericardial access to the heart, including direct access to the left atrium. In certain embodiments, the device may comprise a device and/or an atrial appendage (AA) portal having a configuration such that the distal end of the device and/or the portal can access an atrial appendage while the proximal end of the device and/or portal can extend to outside of the subject. The devices and methods may also include a pericardial portal for emplacement of the device and/or the AA portal. Also, methods for using such devices and/or AA portals and pericardial portals to perform surgery on the heart, and systems (e.g., kits) comprising these devices and/or portals in combination with other therapeutic devices are disclosed.

Abstract: A medical instrument comprising an end effector comprising a first jaw configured to be repositionable with respect to a second jaw, the first and second jaws removably mounted to an open-ended occlusion clip, the end effector configured to configured to be removably coupled to an open-ended occlusion clip with a pair of terminal ends and first and second robotic arms, and wherein the end effector includes at least one of a cavity and a projection configured to be engaged by at least one of the first and second robotic arms.

Abstract: Cryosurgical devices, such as cryosurgical probes (cryoprobes) are disclosed. Some example embodiments may include a cryogenic probe comprising an elongated tube at least partially housing or delineating a fluid supply conduit and a fluid exhaust conduit, the elongated tube including a distal ablation section terminating at a closed distal end, the elongated tube including at least one stagnant fluid pocket interposing an exterior of the conduit and at least one of the fluid supply conduit and the fluid exhaust conduit, and a housing at least partially circumscribing at least a portion of a proximal end of the elongated tube and receiving or delineating at least a portion of the fluid supply conduit and a portion of the fluid exhaust conduit.

Abstract: Methods and devices described herein facilitate improved treatment of body organs.

Abstract: Pericardiotomy devices are disclosed. An example pericardiotomy device includes an elongated shaft and an end effector disposed distally on the shaft. The end effector includes a tip portion and a penetrating element. The tip portion includes an opening configured to engage a target portion of a pericardium and is configured, upon application of vacuum to the tip portion, to separate the target portion of the pericardium from an external surface of a heart. The penetrating element is disposed within the tip portion so that, with vacuum applied to the tip portion, the penetrating element is operative to create an opening in the target portion of the pericardium.

Abstract: Electrosurgical pericardiotomy devices are disclosed. An example electrosurgical pericardiotomy device configured to create an opening through a pericardium may include an end effector comprising a tip portion and at least one electrosurgical electrode. The tip portion may include an opening configured to engage a target portion of a pericardium, and the tip portion may be configured, upon application of vacuum to the tip portion, to separate the target portion of the pericardium from an external surface of a heart. The electrosurgical electrode may be disposed proximate the tip portion so that, with vacuum applied to the tip portion, the target portion of the pericardium contacts the electrosurgical electrode. The electrosurgical electrode may be configured to create an opening through the target portion of the pericardium using electrosurgical energy.

Abstract: Surgical devices and related methods are disclosed. An example end effector for a surgical device may include a first jaw, a second jaw, and an articulating mechanism operable to move the first jaw between an open position, an intermediate position, and a closed position. An example articulating mechanism may include a first jaw mount coupled to the first jaw so that movement of the first jaw mount along a path causes rotation and translation of the first jaw mount and the first jaw. A pivotably mounted crank may operably couple an actuator linkage to the first jaw mount so that moving the actuator linkage rotates the crank, and rotation of the crank may move the first jaw mount along the path.

Abstract: In at least one embodiment, a medical device can comprise an elongate outer sheath that extends along a sheath longitudinal axis and defines a central lumen extending therethrough, the elongate outer sheath can comprise a proximal sheath portion and a distal sheath portion. A first guidewire can comprise a first guidewire end and a second guidewire end, the first guidewire can extend from the first and second guidewire ends through the central lumen and can form a distal looped portion. An occlusion device can be disposed at a distal end of an elongate flexible shaft. The elongate flexible shaft can extend from the proximal sheath portion through the central lumen. The occlusion device can include a guide lumen through which the first guide wire passes.

Abstract: A medical instrument comprising an end effector comprising a first jaw configured to be repositionable with respect to a second jaw, the first and second jaws removably mounted to an open-ended occlusion clip, the end effector configured to configured to be removably coupled to an open-ended occlusion clip with a pair of terminal ends and first and second robotic arms, and wherein the end effector includes at least one of a cavity and a projection configured to be engaged by at least one of the first and second robotic arms.

Abstract: Cryosurgical devices, such as cryosurgical probes (cryoprobes) are disclosed. Some example embodiments may include an elongated shaft at least partially housing or delineating a fluid supply conduit and a fluid exhaust conduit, the elongated shaft including a distal ablation section terminating at a closed distal end, a housing at least partially circumscribing at least a portion of a proximal end of the elongated shaft and receiving or delineating at least a portion of the fluid supply conduit and a portion of the fluid exhaust conduit; and/or a flow restricting element in fluid communication with the fluid exhaust conduit, the flow restricting element regulating the flow of fluid through at least a portion of the fluid exhaust conduit.

Abstract: Various methods of treating a heart of a patient having a cardiac arrhythmia are disclosed. The method can comprise dissecting tissue at an inferior aspect of a right inferior pulmonary vein of the patient to create an oblique sinus defect, dissecting tissue to open a space between a superior vena cava and a left atrium, and dissecting tissue to open a space across a transverse sinus between a pulmonary artery and a roof of the left atrium. The method can further comprise passing a catheter through an oblique sinus defect underneath the heart and beyond a left ventricle and passing a first flexible guiding device across the transverse sinus and under the superior vena cava and the pulmonary artery.

Abstract: Exclusion devices for anatomical structures, and related instruments and related methods, are disclosed. An application instrument for an exclusion device may include an end effector including a head configured to be disposed distally on a shaft, a stationary jaw fixedly disposed on the head and configured to releasably couple to a first clamping portion of an exclusion device, the exclusion device being biased in a closing direction, and a movable jaw movably disposed on the head and configured to releasably couple to a second clamping portion of the exclusion device. The movable jaw may be movable relative to the stationary jaw to reconfigure the exclusion device from a closed configuration to an open configuration. The movable jaw may be oriented generally parallel to the stationary jaw when the exclusion device is in the open configuration and the closed configuration.

Abstract: Exclusion devices for anatomical structures, and related instruments and related methods, are disclosed. An exclusion device for an anatomical structure may include a first beam, a second beam, and/or a first spring operatively coupled to the first beam and the second beam to exert a closing force on the first beam and the second beam. The first spring may be generally U-shaped and/or may include a first end portion and a second end portion generally opposite a connecting portion.

Abstract: Exclusion devices for anatomical structures, and related instruments and related methods, are disclosed. An exclusion device may include a first clamping portion, a second clamping portion opposing the first clamping portion, and/or a biocompatible fabric cover at least partially sheathing the first clamping portion and/or the second clamping portion. The cover may be generally tubular and/or may define a relaxed circumference when the first clamping portion and the second clamping portion are in a closed configuration. At least a portion of the cover may be configured to stretch to a stretched circumference of about 2× to about 3× the relaxed circumference when the first clamping portion and the second clamping portion are reconfigured from the closed configuration to an open configuration.

Abstract: Exclusion devices for anatomical structures, and related instruments and related methods, are disclosed. An exclusion device for an anatomical structure may include a first beam, a second beam, and/or at least one spring operatively coupled to the first beam and the second beam to exert a closing force on the first beam and the second beam and bias the first beam and the second beam in a closing direction. The spring may be operatively coupled to the first beam by a crimp connection.