Abstract: The invention relates to a nucleic acid molecule that binds and/or is complementary to the nucleotide molecule having sequence 5?-GUGGCUAACAGAAGCU (SEQ ID NO 1) and to its use in a method for inducing skipping of exon 44 of the DMD gene in a DMD patient.

Abstract: A multi-purpose beverage pod holder for a beverage brewing apparatus is disclosed comprising a flange adapted to be received in a slot in the brewing apparatus, a screen disposed orthogonal with the flange for allowing fluid to pass therein through, a first cylindrical wall encircling the screen on a first surface of the pod holder, the first cylindrical wall having a first diameter and defining a first packet retainer, and a second cylindrical wall encircling the screen on an opposite surface of the pod holder, the second cylindrical wall having a second diameter that is larger than the first diameter and defining a second packet retainer. The pod holder can be used to brew both espresso and coffee in the same machine depending upon the orientation of the pod holder.

Abstract: Method and apparatus for processing slaughtered poultry that is conveyed in a slaughter line of a slaughter house, in order to establish at the start of said slaughter line whether the poultry was alive or dead on arrival at the slaughter house. Such can include the detection of a body parameter of the slaughtered poultry when the poultry is suspended by the legs in the slaughter line after stunning said poultry, and wherein an absorption spectrum of blood of the slaughtered poultry is determined.

Abstract: A fiber Bragg grating interrogator assembly, comprising: an optical fiber including a fiber Bragg grating (FBG; 122) having a variable Bragg wavelength (?B) and a dynamic range of interest (??dyn,B) over which the Bragg wavelength (?B) can shift during use; —a light source operably connected to the optical fiber, and configured to illuminate the fiber Bragg grating to solicit a response therefrom; and an response analyzer, including: a spectrally selective device having an input port and a plurality of output ports (149-n), wherein the input port is operably connected to the optical fiber and wherein each of the output ports is associated with a respective spectral range (??n), said spectrally selective device being configured to provide a spectral energy distribution of a response of the fiber Bragg grating received on the input port onto said output ports.

Abstract: The present invention relates to a process for preparing a statin precursor, which process comprises a first reaction step, wherein a hydroxy-pyrimidine-carbonitrile is reacted with an organic sulfonyl halide to form the sulfonate-pyrimidine-carbonitrile; a second reaction step, wherein the sulfonate-pyrimidine-carbonitrile is reacted with N-methylmethane sulfonamide to form a pyrimidinyl-sulfonamide; and optionally a third reaction step, wherein the pyrimidinyl-sulfonamide is reacted with a reducing agent. All steps are conducted in toluene as the main solvent.

Abstract: A heater block adapted to be installed in a plasma deposition or plasma etching apparatus that includes a showerhead and a reaction chamber, the heater block being adapted to be arranged in the reaction chamber to support a substrate and includes: at least one through-hole passing through the heater block, and on its upper face a plurality of surfaces separated from each other and defined by a continuous concavity; and the continuous concavity including: a plurality of main concaves or depressions, a plurality of concave channels connecting substantially every two adjacent main concaves or depressions, and a concave or depression, at the center of the heater block, of a different shape or size from the plurality of main concaves or depressions.

Abstract: A lithographic apparatus includes a first table to support a substrate; a second table, not being configured to support a substrate, including a sensor unit to sense a property of a patterned beam of radiation from a projection system, the second table to move under the projection system when the first table is moved out from under the projection system during a substrate exchange, the first and second tables being independently movable from each other; and a liquid supply system to supply a liquid to a space between the projection system and the substrate, the first table, and/or the second table, wherein the second table is configured to provide a confining surface at a bottom of a liquid confinement structure when the first table is removed from under the projection system so as to prevent the liquid from leaking out into the remainder of the lithographic apparatus.

Abstract: A method, apparatus and computer program product are provided to disambiguate probe points within an ambiguous probe regions to permit more reliable association with a road segment. In regards to a method, probe trajectory identifiers (IDs) of probe points along at least a portion of the first and second branches that lead away from an ambiguous probe region are separately identified and form first and second sets of probe trajectory IDs, respectively. For the ambiguous probe region, the probe trajectory IDs of probe points along a third branch that leads toward the ambiguous probe region are identified and form a third set of probe trajectory IDs. The method also includes classifying probe trajectory IDs from the third set as being associated with the first branch or the second branch in an instance in which the probe trajectory IDs are additionally included in the first set or the second set, respectively.

Abstract: An ink composition comprising an oxygen sensitive dye capable of fluorescing in a manner proportional to oxygen content; and a polymer matrix for the dye, the polymer matrix having units with pendant sulphonic acid or phosphonic acid groups or salts or esters of such groups, can be used with an appropriate meter to measure the oxygen content of packages in a non-invasive manner.

Abstract: An apparatus to remove ions from water. The apparatus may include a stack having a first electrode including a first current collector, a spacer on top of the first electrode, and a second electrode on top of the spacer. The stack may have a tray to hold and position the stack within a housing of the apparatus and thus may improve the manufacturability of the apparatus.

Abstract: The invention relates to a procatalyst for polymerization of olefins. The invention also relates to a process for preparing said procatalyst. Furthermore, the invention is directed to a catalyst system for polymerization of olefins comprising the said procatalyst, a co-catalyst and optionally an external electron donor; a process of preparing polyolefins by contacting an olefin with said catalyst system and to polyolefins obtained or obtainable by said process. The invention also relates to the use of said procatalyst in the polymerization of olefins.

Abstract: A power supply is disclosed. The power supply includes a switch to regulate an input voltage and a current sense transistor to sense current through the switch. The power supply further includes a switching control to control a switching frequency of the switch. A programmable pulse skip circuit coupled to the switching control is also included. The switching control is configured to alter the switching frequency based on a pulse skip control signal received from the programmable pulse skip circuit. The programmable pulse skip circuit produces the pulse skip control signal based on an external control signal inputted to the programmable pulse skip circuit and the sensed current by the current sense transistor.

Abstract: This invention relates to a device comprising a routing controller for routing messages to a plurality of node devices of a network, the routing controller comprising at least one global instance enabling the routing of messages to a routing set of node devices, at least one local instance for routing packets to a neighbor node device neighboring the device, wherein the neighbor node device is selected regardless whether the neighbor node device belongs to the routing set of node devices, and wherein the routing controller is configured to use the local instance for routing of multicast messages to the node devices.

Abstract: A vehicle accelerometer system comprises an accelerometer for installation in a vehicle, a processor for selection of accelerometer output data items for inclusion in an accelerometer output data set representative of measurements by the accelerometer at a plurality of different vehicle locations, each accelerometer output data item being representative of a respective measurement by the accelerometer, and a storage device for storing the accelerometer output data set, wherein the processor is configured to process the accelerometer output data set to determine an orientation output representative of the orientation of the accelerometer with respect to the vehicle.

Abstract: A core element is provided, having the shape of a block with a first surface, a second surface situated opposite the first surface, mutually facing longitudinal side faces, and mutually facing transverse side faces. The first surface is provided with the first groove that is a continuous groove which extends parallel to the longitudinal side faces. The longitudinal side faces are provided with the side wall grooves, the side wall grooves being continuous side wall grooves which extend between the first surface and the second surface and are separated from the first groove in the first surface.

Abstract: The present invention provides a hypo-allergenic cross-linked protein for use in the prevention of an allergy against milk proteins, or for use in the induction of oral tolerance for milk proteins, said cross-linked protein being selected from cross-linked casein, cross-linked caseinate and combinations thereof. The invention further provides a nutritional composition for use in the prevention of an allergy against milk proteins or for use in the induction of oral tolerance against milk proteins.

Abstract: A new and distinct cultivar of Hydrangea plant named ‘HP217902’, characterized by its compact, upright and rounded plant habit; vigorous growth habit and rapid growth rate; freely branching habit with strong, thick and sturdy stems; early, freely and uniformly flowering habit; broadly pyramidal inflorescences with numerous yellow green-colored sterile flowers; and good garden performance.

Abstract: A new and distinct cultivar of Calibrachoa plant named ‘Docabloroq’, characterized by its semi-upright to outwardly spreading, trailing and decumbent plant habit; vigorous growth habit; freely branching habit; early and freely flowering habit; large flowers with light purple and red purple bi-colored petals; and good garden performance.