Abstract: A catheter assembly for performing a thrombectomy and methods of use, the catheter assembly including a catheter sheath and a dilation and capture assembly slidably positioned within the catheter sheath. The dilation and capture assembly includes a catheter having a balloon portion at a distal end of the catheter, and a retrieval basket. The balloon portion is selectively inflatable and deflatable between respectively a maceration orientation and a delivery orientation. The retrieval basket is deployable from a delivery configuration mounted to the balloon portion and a retrieving configuration axially displaced from the distal end of the catheter.

Abstract: Embodiments herein are directed to a tissue sampling device. The tissue sampling device includes a housing and a sub-frame positioned within the housing. A stylet hub is movably coupled to the sub-frame and has an outer surface and a resilient member extending from the outer surface. The resilient member is configured to transition between an unflexed state and a flexed state. The stylet hub is movable between a cocked position and an activated position along a central axis with respect to the sub-frame. A cannula hub is movably coupled to the sub-frame and movable between the cocked position the activated position the central axis with respect to the sub-frame. The resilient member is actuated between the flexed state and the unflexed state when the resilient member is in contact with a portion of the sub-frame as a function of a kinetic energy input exerted on the resilient member.

Abstract: A venous thrombectomy device includes a net assembly and a dislodger assembly that are operated independent of each other. The net assembly includes a wire and an expandable net secured at a distal end of the wire, wherein, when in an expanded state, the expandable net defines an interior collection volume with a mouth that opens proximally when the net is advanced distally beyond the thrombus and expanded. The dislodger assembly includes at least one node secured at a distal end of a shaft, wherein the wire of the net assembly extends through a lumen of the shaft such that the dislodger assembly may translate axially over and rotate about the wire, relative to the net.

Abstract: Refreshing stylets, catheter systems, and methods thereof. The refreshing stylet can be configured to fit within a lumen of a catheter such as hemodialysis catheter. The refreshing stylet can include an elongated hollow body having a proximal portion coupled to a needleless connector, a distal portion ending in a distal tip, an interior surface, an exterior surface, and a side hole. The exterior surface can be coated with a sustained-release formulation including one or more anti-thrombotic agents. The sustained-release formulation can be configured to contact a luminal surface of the catheter and prevent thrombus formation thereon. The side hole can be configured to provide a locking solution to the lumen of the catheter for locking the catheter between uses.

Abstract: An implant for use in a lung access procedure to aid in preventing pneumothorax includes a tubular body that has a lumen, a proximal end, and a distal end portion that terminates at a distal end. The tubular body has a longitudinal axis and has a side wall that radially surrounds the lumen. The side wall has an exterior surface. An anchor member is connected to the tubular body, wherein the anchor member is movable relative to the tubular body from a collapsed state to a deployed state. At least one suture is connected to the tubular body, wherein the at least one suture extends in a proximal direction from the proximal end of the tubular body.

Abstract: A medical sealant applicator device for delivery of a multi-component sealant including a first body having a base, a first syringe plunger, a second syringe plunger, and a longitudinal channel, laterally interposed between the first syringe plunger and the second syringe plunger. Each of the first syringe plunger and the second syringe plunger is oriented to extend in a first direction from the base. The first syringe plunger has a first free end having a first proximal plunger piston. The second syringe plunger having a second free end having a second proximal plunger piston. A second body of the medical sealant application device has a first syringe chamber, a second syringe chamber, and a longitudinal fluid chamber laterally interposed between the first syringe chamber and the second syringe chamber. The longitudinal fluid chamber has a proximal end and a distal end.

Abstract: Disclosed are compositions, dispensers, and methods thereof for establishing a urine passageway through a ureter. For example, a composition can include, in some embodiments, a primary solid phase and a secondary solid phase. The primary solid phase can include a monomer, a pre-polymer, or a mixture thereof configured to commence polymerization into a polymeric form in the ureter when contacted with a fluid such as urine or saline. The secondary solid phase is dispersed in the primary solid phase. The secondary solid phase can include a leachable component. The leachable component is configured to leach from the polymeric form when contacted with a sufficient amount of a same or different fluid. The leachable component is also configured to form pores of an open-pore network throughout the polymeric form when leached from the polymeric form, thereby establishing the urine passageway through the ureter.

Abstract: A cauterization device includes a handpiece configured to be grasped by a user. The handpiece includes a housing, a heat control circuit, and a control switch. A cannula has a cannula lumen, a cannula side wall surrounding the cannula lumen, a cannula proximal end portion, and a cannula distal end. The cannula proximal end portion is coupled to the housing of the handpiece. A stylet has a shaft portion and a distal heat conductive body. The distal heat conductive body is electrically coupled to the heat control circuit. The distal heat conductive body has a first end and a tapered portion that distally terminates at a second end. The shaft portion is located, at least in part, in the cannula lumen. The insulator member is configured to thermally separate the cannula distal end from the distal heat conductive body of the stylet.

Abstract: A rotational atherectomy device includes an elongate flexible shaft and an abrasive element connected to a distal end of the elongate flexible shaft. A handle includes a housing that includes an electric motor operatively connected to the elongate flexible shaft to rotate the elongate flexible shaft. A power source is electrically connected to the electric motor for supplying power thereto. A controller is configured to monitor a motor supply current of the electric motor and monitor a speed of the electric motor using a signal from a sensor. If the motor supply current is above a first predetermined threshold, the controller reduces a speed of the electric motor while attempting to maintain motor supply current of the electric motor. Then, if the motor supply current is above a second predetermined threshold higher than the first predetermined threshold, the controller stops the electric motor.

Abstract: A catheter for removal of material from hollow bodies is provided. The catheter may include a catheter body defining an opening and a cutting ribbon extending around the catheter body. The cutting ribbon extends out of the opening of the catheter body and has an expanded configuration having a relatively large hoop size and a retracted configuration having a relatively small hoop size. The cutting ribbon includes an elongated ribbon body, and a blade disposed at a side edge of the ribbon body.

Abstract: An adjustable interface device for connecting two components of a medical device includes an elongate body and an elongate member. The elongate body has a first end, a second end, an interior channel, and a side wall that surrounds the interior channel. The side wall defines a first connector portion adjacent the second end. The first connector portion attaches to a respective one of the components of the medical device. The elongate member has a head end portion and a shaft portion that longitudinally extends from the head end portion. The shaft portion is located at least partially in the interior channel of the elongate body. The shaft portion is configured to slidably move axially along the longitudinal axis to adjust a length of the adjustable interface device. The head end portion defines a second connector portion that attaches to another of the components of the medical device.

Abstract: The present disclosure relates to ultrasonic catheters including vibration wires that are positionable in a retracted position and an extended position, and their methods of use. In operation, catheters according to the present disclosure are operable in an occlusion crossing mode, in which the catheter emits ultrasonic energy with the vibration wires in the retracted position and in an atherectomy mode, in which the catheter emits ultrasonic energy with the vibration wires in the extended position, causing the vibration wires to oscillate. The vibration wires may directly or indirectly engage plaque within an artery, causing the plaque to break free from the artery wall. The oscillation of the vibration wires may be less abrasive than conventional cutting elements used in atherectomy procedures, such that catheters according to the present disclosure may cause less trauma to artery walls as compared to conventional atherectomy devices.

Abstract: A vascular device insertion system includes a support catheter having a hub, a flexible elongate member that extends distally from the hub, and a catheter lumen that extends through the hub and the flexible elongate member. An insertion module housing is configured to contain a motor having a hollow motor shaft. The hollow motor shaft has a proximal end, a distal end, a distal end portion, and an elongate opening that extends from the proximal end to the distal end. The distal end portion of the hollow motor shaft is configured to couple to the hub of the support catheter. The elongate opening of the hollow motor shaft and the catheter lumen of the support catheter together define a continuous passage. A motor controller is electrically coupled to the motor, and is configured to rotationally oscillate the hollow motor shaft to in turn rotationally oscillate the support catheter.

Abstract: A thrombectomy device for removing a material from a subject includes a catheter, a diaphragm, and a vacuum. The catheter includes an outer body defining a lumen extending therethrough. The diaphragm is coupled to the catheter and is moveable between an open diaphragm configuration and a closed diaphragm configuration. The diaphragm allows movement of the material through the lumen when in the open diaphragm configuration and prevents movement of the material through the lumen when in the closed diaphragm configuration. The vacuum is in communication with the lumen and is operable to exert a vacuum pressure on the diaphragm. The vacuum pressure is operable to move the diaphragm from the open diaphragm configuration to the closed diaphragm configuration.

Abstract: Embodiments herein are directed to an occlusion device that includes a body, a pair of lobes, and an adjustment assembly. One of the pair of lobes positioned at a distal portion of the body and the other one is positioned at a proximal portion. The body includes an adjustment assembly positioned between the distal and the proximal portions to change a distance between the pair of lobes. The adjustment assembly includes a receiving member and an elongated member. The elongated member is configured to move the body between an extended position and a retracted position, such that in the retracted position, the elongated member is received within an inner diameter of the receiving member. In the extended position, the elongated member is extended away from a first end of the receiving member such that the distance between the pair of lobes is increased.

Abstract: A damping assembly for a core wire of an ultrasonic catheter assembly includes a body for receiving the core wire. The body includes a bore extending from a proximal end of the body. The bore is defined by an interior surface of the body and includes an insertion region at the proximal end and a compression region disposed distal to the insertion region. A plurality of compression members are disposed within the compression region of the bore. A retention member extends at least partially into the compression region to axially compress the plurality of compression members. The interior surface of the body defining the insertion region of the bore corresponds in shape to at least a portion of an exterior surface of the retention member to facilitate insertion of the retention member into the bore.

Abstract: Disclosed herein is a catheter defining a first lumen and a second lumen. A proximal portion of the catheter can be configured to separate along a longitudinal axis to allow a proximal portion of the first lumen to be trimmed to a different length than a proximal portion of the second lumen. The catheter can include a septum disposed laterally between the first lumen and the second lumen configured to facilitate separation of the first lumen from the second lumen. The septum can include grooves, perforations, and can be formed of different materials to facilitate separation. Further the septum can include a wire configured to facilitate separation of the first lumen from the second lumen. Separation and/or trimming of the lumens positions the subcutaneous access ports in a spaced apart relationship to differentiate between infusion and aspiration lumens of the catheter.

Abstract: An implantable device for treating hypervolemia includes an expandable chamber, a rigid chamber coupled to the expandable chamber, a first valve in fluid communication with both the expandable chamber and the rigid chamber, a second valve in fluid communication with the rigid chamber and an exterior of the implantable device, and an osmotic fluid. The expandable chamber includes a first semipermeable membrane. The rigid chamber includes a piston. The first valve has an open position to permit fluid flow between the expandable chamber and the rigid chamber. The second valve has an open position to permit fluid flow from the rigid chamber to the exterior of the implantable device. The osmotic fluid has a higher osmotic concentration than bodily fluid. The osmotic fluid is designed to absorb water from the bodily fluid through the first semipermeable membrane.

Abstract: Delivery devices, as well as systems incorporating the same and methods of using the same are disclosed. A needle assembly includes a hub having first and second input ports and an auxiliary port, and an injection needle assembly. The injection needle assembly includes an elongate hollow stylet extending distally from the hub that includes an outer side wall defining an outer lumen fluidly coupled to the auxiliary port, a first inner side wall defining a middle lumen disposed within the outer lumen that is fluidly coupled to the first input port, a second inner side wall defining an inner lumen disposed within the middle lumen that is fluidly coupled to the second input port, and a mixing chamber fluidly coupled to the outer lumen, the middle lumen, and the inner lumen.

Abstract: A drainage system includes a fluid-receiving container that includes an inlet and a drainage conduit communicatively coupled to the inlet of the fluid-receiving container. A first one-way valve is along the drainage conduit that provides a one-way fluid flow direction through the drainage conduit into the fluid-receiving volume. A displacement body is out-of-line with the drainage conduit and fluidly connected to the drainage conduit. The displacement body is configured to be actuated and released to provide a negative pressure to a fluid-receiving passageway through the drainage conduit. Actuation of the displacement body displaces air within the fluid-receiving passageway, the air being forced into the fluid-receiving volume by a second one-way valve and inhibited from escaping the fluid-receiving volume by the first one-way valve.