Patents Assigned to BASF Plant Science GmbH
  • Patent number: 8212111
    Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches or seed storage proteins.
    Type: Grant
    Filed: November 10, 2010
    Date of Patent: July 3, 2012
    Assignee: BASF Plant Science GmbH
    Inventors: Volker Mittendorf, Heiko A. Haertel, Petra Cirpus
  • Publication number: 20120156718
    Abstract: The present invention relates to optimized ketolase coding sequences, corresponding coding sequences and genetic constructs alone or in combination with beta-cyclase coding sequences, their use for the expression in plants, in particular in plants of the genus Tagetes, to such genetically modified plants, to a process for the preparation of carotenoid products by culturing the genetically modified plants. The present invention further relates to the expression of optimized ketolase coding sequences alone or in combination with beta-cyclase coding sequences under control of an Antirrhinum majus ANTHIRRHINUM FIDDLEHEAD (AFI) promoter, In addition the invention relates to the use of an AFI promoter for heterologous gene expression, preferably for flower-specific expression of genes in plants of the genus Tagetes, to the genetically modified plants of the genus Tagetes, and to a process for producing biosynthetic products by cultivating the genetically modified plants.
    Type: Application
    Filed: December 8, 2009
    Publication date: June 21, 2012
    Applicant: BASF Plant Science GmbH
    Inventors: Ralf Flachmann, Irina Wenderoth, Christel Renate Schopter, Bettina Tschiersch, Hannia Bridg-Giannakopoulos, Michael Leps, Ute Linemann, George Mather Sauer
  • Patent number: 8188339
    Abstract: Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana, Brassica napus, and Physcomitrella patens are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches, or seed storage proteins.
    Type: Grant
    Filed: November 10, 2010
    Date of Patent: May 29, 2012
    Assignee: BASF Plant Science GmbH
    Inventors: Volker Mittendorf, Heiko A. Haertel, Jörg Bauer, Oliver Oswald
  • Publication number: 20120124702
    Abstract: The present invention relates generally to the field of molecular biology and concerns a method for enhancing yield-related traits in plants, in particular for increasing plant yield and/or early vigour, relative to control plants. More specifically, the present invention concerns a method for enhancing yield-related traits comprising modifying the expression of a nucleic acid encoding a HAL3 polypeptide, MADS15 polypeptide, PLT transcription factor polypeptide, basic/helix-loop-helix (bHLH) transcription factor, or SPL15 transcription factor. The invention also provides constructs useful in the methods of the invention.
    Type: Application
    Filed: March 30, 2007
    Publication date: May 17, 2012
    Applicant: BASF PLANT SCIENCE GMBH
    Inventors: Christophe Reuzeau, Valerie Frankard, Ana Isabel Sanz Molinero
  • Patent number: 8178751
    Abstract: The invention relates to a method of generating or increasing a pathogen resistance in plants by reducing the expression of at least one stomatin polypeptide or a functional equivalent thereof. The invention relates to novel nucleic acid sequences coding for a Hordeum vulgare stomatin (HvSTM1) polynucleotide and describes homologous sequences (STM1) thereof, and to their use in methods for obtaining a pathogen resistance in plants, and to nucleic acid constructs, expression cassettes and vectors which comprise these sequences and which are suitable for mediating a fungal resistance in plants. The invention furthermore relates to transgenic organisms, in particular plants, which are transformed with these expression cassettes or vectors, and to cultures, parts or transgenic propagation material derived therefrom.
    Type: Grant
    Filed: January 4, 2007
    Date of Patent: May 15, 2012
    Assignee: BASF Plant Science GmbH
    Inventors: Markus Frank, Patrick Schweizer, Dimitar Douchkov
  • Patent number: 8134046
    Abstract: The present invention relates to a process for producing arachidonic acid and/or eicosapentaenoic acid in transgenic useful plants by introducing into the plant nucleic acids coding for polypeptides having ?6-desaturase, ?6-elongase or ?5-desaturase activity. Furthermore, a gene coding for an ?3-desaturase is advantageously expressed in said useful plants. In another advantageous embodiment of the process, further nucleic acid sequences coding for polypeptides of fatty acid or lipid metabolism biosynthesis may be expressed in the plants. Particularly advantageous nucleic acid sequences here are those coding for a ?8-desaturase, ?12-desaturase, ?15-desaturase, ?4-desaturase, ?9-elongase and/or ?5-elongase activity. The invention further relates to the use of the oils, lipids and/or fatty acids produced in the process according to the invention in feedstuffs or foodstuffs, cosmetics or pharmaceuticals.
    Type: Grant
    Filed: August 1, 2006
    Date of Patent: March 13, 2012
    Assignee: BASF Plant Science GmbH
    Inventors: Petra Cirpus, Jörg Bauer, Xiao Qiu, Guohai Wu, Nagamani Datla, Martin Truksa
  • Publication number: 20120054922
    Abstract: The invention relates to methods for the identification and use of introns with gene expression enhancing properties. The teaching of this invention enables the identification of introns causing intron-mediated enhancement (IME) of gene expression. The invention furthermore relates to recombinant expression construct and vectors comprising said IME-introns operably linked with a promoter sequence and a nucleic acid sequence. The present invention also relates to transgenic plants and plant cells transformed with these recombinant expression constructs or vectors, to cultures, parts or propagation material derived there from, and to the use of same for the preparation of foodstuffs, animal feeds, seed, pharmaceuticals or fine chemicals, to improve plant biomass, yield, or provide desirable phenotypes.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 1, 2012
    Applicant: BASF Plant Science GmbH
    Inventors: Hee-Sook Song, Christian Dammann, Marc Morra, Jeffrey A. Brown, Liqun Xing, Hongmei Jia
  • Patent number: 8119861
    Abstract: The invention relates to nucleic acid derived from Perkinsus marinus which encodes a 9-elongase, a ?8-desaturase and a ?5-desaturase enzyme. All of the coding sequences can be transcribed as a single transcript.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: February 21, 2012
    Assignee: BASF Plant Science GmbH
    Inventors: Johnathan A. Napier, Olga Sayanova, Monica Venegas Caleron
  • Publication number: 20120030836
    Abstract: The present invention relates generally to the field of molecular biology and concerns a method for increasing various plant yield-related traits by increasing expression in a plant of a nucleic acid sequence encoding a Brevis Radix-like (BRXL) polypeptide. The present invention also concerns plants having increased expression of a nucleic acid sequence encoding a BRXL polypeptide, which plants have increased yield-related traits relative to control plants. The invention additionally relates to nucleic acid sequences, nucleic acid constructs, vectors and plants containing said nucleic acid sequences.
    Type: Application
    Filed: November 26, 2009
    Publication date: February 2, 2012
    Applicant: BASF Plant Science GmbH
    Inventors: Yves Hatzfeld, Valerie Frankard, Christophe Reuzeau, Ana Isabel Sanz Molinero, Koen Bruynseels
  • Publication number: 20120017332
    Abstract: The present invention relates to a new process for the production of arachidonic acid and/or eicosapentaenoic acid in plants through the co-expression of a ?-12-/?-15-desaturase, ?-9-elongase, ?-8-desaturase and a ?-5-desaturase and a process for the production of lipids or oils having an increased content of unsaturated fatty acids, in particular ?-3 and ?-6 fatty acids having at least two double bonds and a 18 or 20 carbon atom chain length. Preferably the arachidonic acid and eicosapentaenoic acid are produced in at least a 1:2 ratio. The invention furthermore relates to the production of a transgenic plants, preferably a transgenic crop plant, having an increased content of arachidonic acid and/or eicosapentaenoic acid, oils or lipids containing C18- or C20-fatty acids with a double bond in position ?5, 8, 9, 11, 12, 14, 15 or 17 of the fatty acid produced, respectively due to the expression of the ?-12-/?-15-desaturase, of the ?-9-elongase, of the ?-8-desaturase and of the ?-5-desaturase in the plant.
    Type: Application
    Filed: July 19, 2011
    Publication date: January 19, 2012
    Applicant: BASF Plant Science GmbH
    Inventors: Johnathan A. Napier, Olga Sayanova
  • Patent number: 8097769
    Abstract: A transgenic crop plant transformed by a 1-AminoCyclopropane-1-Carboxylate Deaminase-like Polypeptide (ACCDP) coding nucleic acid, wherein expression of the nucleic acid sequence in the crop plant results in the plant's increased root growth, and/or increased yield, and/or increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic crop plants. Also provided are isolated novel ACCDPs, and isolated novel nucleic acids encoding ACCDPs, and vectors and transgenic plant containing the same.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: January 17, 2012
    Assignee: BASF Plant Science GmbH
    Inventors: Rodrigo Sarria-Millan, Eric R. Garr, Jamie Haertel, Damian Allen, Bryan McKersie
  • Publication number: 20120011618
    Abstract: The present invention relates to a new process for the production of arachidonic acid and/or eicosapentaenoic acid in plants through the co-expression of a ?-12-/?-15-desaturase, ?-9-elongase, ?-8-desaturase and a ?-5-desaturase and a process for the production of lipids or oils having an increased content of unsaturated fatty acids, in particular ?-3 and ?-6 fatty acids having at least two double bonds and a 18 or 20 carbon atom chain length. Preferably the arachidonic acid and eicosapentaenoic acid are produced in at least a 1:2 ratio. The invention furthermore relates to the production of a transgenic plants, preferably a transgenic crop plant, having an increased content of arachidonic acid and/or eicosapentaenoic acid, oils or lipids containing C18- or C20-fatty acids with a double bond in position 5, 8, 9, 11, 12, 14, 15 or 17 of the fatty acid produced, respectively due to the expression of the ?-12-/?-15-desaturase, of the ?-9-elongase, of the ?-8-desaturase and of the ?-5-desaturase in the plant.
    Type: Application
    Filed: July 19, 2011
    Publication date: January 12, 2012
    Applicant: BASF Plant Science GmbH
    Inventors: Johnathan A. Napier, Olga Sayanova
  • Publication number: 20120005777
    Abstract: The present invention relates to a process for the production of fine chemicals in a microorganism, a plant cell, a plant, a plant tissue or parts thereof. The invention furthermore relates to nucleic acid molecules, polypeptides, nucleic acid constructs, vectors, antisense molecules, antibodies, host cells, plant tissue, propagtion material, harvested material, plants, microorganisms as well as agricultural compositions and to their use.
    Type: Application
    Filed: July 12, 2011
    Publication date: January 5, 2012
    Applicant: BASF Plant Science GmbH
    Inventors: Gunnar Plesch, Piotr Puzio, Astrid Blau, Ralf Looser, Birgit Wendel, Beate Kamlage, Agnes Chardonnens, Amber Shirley, Xi-Qing Wang, Rodrigo Sarria-Millan, Bryan McKersie, Ruoying Chen
  • Patent number: 8088971
    Abstract: The invention relates to methods for the identification and use of introns with gene expression enhancing properties. The teaching of this invention enables the identification of introns causing intron-mediated enhancement (IME) of gene expression. The invention furthermore relates to recombinant expression construct and vectors comprising said IME-introns operably linked with a promoter sequence and a nucleic acid sequence. The present invention also relates to transgenic plants and plant cells transformed with these recombinant expression constructs or vectors, to cultures, parts or propagation material derived there from, and to the use of same for the preparation of foodstuffs, animal feeds, seed, pharmaceuticals or fine chemicals, to improve plant biomass, yield, or provide desirable phenotypes.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: January 3, 2012
    Assignee: BASF Plant Science GmbH
    Inventors: Hee-Sook Song, Marc Morra, Liqun Xing, Hongmei Jia
  • Patent number: 8088974
    Abstract: The present invention relates to a method for the production of unsaturated fatty acids with at least two double bonds. The invention furthermore relates to the use of nucleic acid sequences SEQ ID NO: 1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 11 encoding polypeptides having desaturase activity in the method and for generating a transgenic organism, preferably a transgenic plant or a transgenic microorganism, with an increased content of fatty acids, oils or lipids with unsaturated C18-, C20-, or C22-fatty acids, and to their homologs or derivatives, to gene constructs encompassing these genes, and to their use alone or in combination with biosynthesis genes of polyunsaturated fatty acids. The invention also relates to multiexpression cassettes for seed-specific expression, and to vectors or organisms which encompass a desaturase gene alone or in combination with further desaturases and/or elongase genes or homologs using said expression cassettes.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: January 3, 2012
    Assignee: BASF Plant Science GmbH
    Inventors: Jens Lerchl, Andreas Renz, Ernst Heinz, Frederic Domergue, Ulrich Zähringer
  • Publication number: 20110321196
    Abstract: The present invention pertains transgenic plant cells and mature plants comprising Oxidoreductase Stress Related Proteins (ORSRP) resulting in increased tolerance and/or resistance to environmental stress as compared to non-transformed wild type cells and methods of producing such plant cells or plants. Further object of the present invention are isolated ORSRPs or ORSRP encoding nucleic acids from plants.
    Type: Application
    Filed: April 29, 2011
    Publication date: December 29, 2011
    Applicant: BASF Plant Science GmbH
    Inventors: Agnes Chardonnens, Piotr Puzio
  • Publication number: 20110321197
    Abstract: A method for producing a plant with increased yield as compared to a corresponding wild type plant whereby the method comprises at least the following step: increasing or generating in a plant or a part thereof one or more activities selected from the group consisting of 17.6 kDa class I heat shock protein, 26.
    Type: Application
    Filed: October 2, 2009
    Publication date: December 29, 2011
    Applicant: BASF Plant Science GmbH
    Inventors: Hardy Schön, Oliver Thimm, Gerhard Ritte, Oliver Bläsing, Koen Bruynseels, Yves Hatzfeld, Valerie Frankard, Ana Isabel Sanz Molinero, Christophe Reuzeau, Steven Vandenabeele
  • Patent number: 8076142
    Abstract: Disclosed herein are rooted plant assay systems, methods of making rooted plant assay systems, and methods of using rooted plant assay systems for high throughput screening of test polynucleotides for their ability to effect phenotypic traits having agricultural value.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: December 13, 2011
    Assignee: BASF Plant Sciences GmbH
    Inventors: Xiang Huang, Ming Cheng, Haiping Hong, Yan Liu, Kangfeng Mei
  • Patent number: 8071383
    Abstract: The present invention relates to improved methods and means for transformation of soybean (Glycine max) based on a D-alanine and/or D-serine selection.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: December 6, 2011
    Assignee: BASF Plant Science GmbH
    Inventors: Diana Arias, Sara Price, Leslie Grist, Ming Cheng, Haiping Hong, Libby Bernal, Paula Olhoft, Hee-Sook Song, Luke Mankin
  • Patent number: 8067668
    Abstract: The invention relates to methods for generating or increasing a pathogen resistance in plants by reducing the expression, activity or function of an NADPH oxidase.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: November 29, 2011
    Assignee: BASF Plant Science GmbH
    Inventors: Karl-Heinz Kogel, Ralph Hückelhoven, Marco Trujillo