Patents Assigned to Bayer Healthcare AG
  • Pharmaceutical Composition
    Publication number: 20080248957
    Abstract: A pharmaceutical composition is provided comprising an active pharmaceutical composition and a water-soluble eutectic composition, the resultant mixture being formed into a solid, water-soluble dosage form.
    Type: Application
    Filed: August 27, 2005
    Publication date: October 9, 2008
    Applicant: BAYER HEALTHCARE AG
    Inventors: Ernest Schay, Walter Focke, Lushane Walbrugh
  • Use of Substituted 2-Thio-3,5-Dicyano-4-Phenyl-6-Aminopyridines In the Treatment of Nausea and Vomiting
    Publication number: 20080249133
    Abstract: The present invention relates to the use of substituted 2-thio-3,5-dicyano-4-phenyl-6-amino-pyridines of the formula (I) for production of a medicament for the prophylaxis and/or treatment of nausea and vomiting.
    Type: Application
    Filed: June 23, 2005
    Publication date: October 9, 2008
    Applicant: Bayer Healthcare AG
    Inventors: Thomas Krahn, Wolfgang Thielemann, Ulrich Rosentreter, Nicole Diedrichs, Thomas Kramer
  • Pyrrolopyridine-Substituted Benzol Derivatives for Treating Cardiovascular Diseases
    Publication number: 20080249105
    Abstract: The invention relates to heteroaryl-substituted benzenes, to a process for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular cardiovascular disorders.
    Type: Application
    Filed: November 26, 2004
    Publication date: October 9, 2008
    Applicant: Bayer Healthcare AG
    Inventors: Samir Bennabi, Heike Heckroth, Hartmut Schirok, Joachim Mittendorf, Raimund Kast, Johannes-Peter Stasch, Mark Jean Gnoth, Klaus Minter, Dieter Lang, Santiago Figueroa Perez, Marcus Bauser, Achim Feurer, Heimo Ehmke
  • Pharmaceutical Composition for the Treatment of Cancer
    Publication number: 20080242707
    Abstract: The present invention pertains to a pharmaceutical composition comprising the compound of the formula (I) in a high concentration and at least one pharmaceutically acceptable excipient, the use of the composition for the treatment of hyper-proliferative diseases, such as cancer, either as a sole agent, or in combination with other anti-cancer therapies, and the process for preparing of said composition.
    Type: Application
    Filed: February 22, 2006
    Publication date: October 2, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Fritz Schuckler, Axel Wollenschlager
  • Morpoline-bridged indazole derivatives
    Patent number: 7427617
    Abstract: The present invention relates to novel morpholine-bridged indazole derivatives having the formula which stimulate soluble guanylate cyclase, to a process for the preparation thereof, and to pharmaceutical compositions containing them. These compounds are useful for the treatment of disorders of the central nervous system.
    Type: Grant
    Filed: September 16, 2003
    Date of Patent: September 23, 2008
    Assignee: Bayer Healthcare AG
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard König, Johannes-Peter Stasch, Frank Wunder, Dieter Lang, Elke Stahl, Thomas Schenke, Rudy Schreiber
  • Hydroxy-tetrahydro-naphthalenylurea derivatives
    Patent number: 7423175
    Abstract: This invention relates to hydroxy-tetrahydro-naphthalenylurea derivatives and salts thereof which are useful as active ingredients of pharmaceutical preparations. The hydroxy-tetrahydro-naphthalenylurea derivatives of the present invention have an excellent activity as VR1 antagonist and are useful for the prophylaxis and treatment of diseases associated with VR1 activity, in particular for the treatment of urinary incontinence, urge urinary incontinence, overactive bladder, chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, inflammatory disorders, asthma and COPD.
    Type: Grant
    Filed: February 5, 2004
    Date of Patent: September 9, 2008
    Assignee: Bayer Healthcare AG
    Inventors: Takeshi Yura, Muneto Mogi, Hiroshi Fujishima, Klaus Urbahns, Tsutomu Masuda, Yasuhiro Tsukimi, Masaomi Tajimi, Noriyuki Yamamoto, Nagahiro Yoshida, Toshiya Moriwaki
  • Substituted Benzyloxy-Phenylmethylamide Derivatives
    Publication number: 20080214654
    Abstract: The present invention relates to novel substituted benzyloxy-phenylmethylamide derivatives, processes for their preparation, and their use in medicaments, especially for the prophylaxis and treatment of diseases associated with Cold Menthol Receptor 1 (CMR-1) activity, in particular for the treatment of urological diseases or disorders, such as detrusor overactivity (overactive bladder), urinary incontinence, neurogenic detrusor oeractivity (detrusor hyperflexia), idiopathic detrusor overactivity (detrusor instability), benign prostatic hyperplasia, and lower urinary tract symptoms; chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, and inflammatory disorders such as asthma and chronic obstructive pulmonary (or airways) disease (COPD).
    Type: Application
    Filed: October 12, 2005
    Publication date: September 4, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Thomas Lampe, Cristina Alonso-Alija, Beatrix Stelte-Ludwig, Peter Sandner, Marcus Bauser, Hartmut Beck, Klemens Lustig, Ulrich Rosentreter, Elke Stahl, Hiroko Takagi
  • Parasiticidal Compositions
    Publication number: 20080214632
    Abstract: The present invention relates to products comprising a macrocylic lactone and an amidine, which products are suitable for controlling parasites, in particular ectoparasites, on animals.
    Type: Application
    Filed: March 5, 2005
    Publication date: September 4, 2008
    Applicant: BAYER HEALTHCARE AG
    Inventors: Hans-Dieter Hamel, Josef Heine, Christoph Hubo, Wolfgang Jiritschka, Dirk Mertin
  • Cyclic Iminocarbamates And Their Use
    Publication number: 20080214533
    Abstract: The invention relates to novel cyclic iminocarbamates of formula (I), wherein R1, R2, R3, A, Z, and n have the meanings recited in the description, to a method for the production thereof, to pharmaceutical compositions containing such materials, and to methods for the treatment and/or prophylaxis of thromboembolic diseases using them.
    Type: Application
    Filed: November 22, 2005
    Publication date: September 4, 2008
    Applicant: BAYER HEALTHCARE AG
    Inventors: Susanne Rohrig, Jens Pohlmann, Sabine Arndt, Mario Jeske, Metin Akbaba, Elisabeth Perzborn, Christoph Gerdes, Karl-Heinz Schlemmer, Arounarith Tuch, Mario Lobell, Peter Nell, Nils Burkhardt
  • N-Biarylamides
    Publication number: 20080214602
    Abstract: The invention relates to N-biarylamides useful for the prophylaxis and/or treatment of impairments of perception, concentration, learning and/or memory, and to processes for preparing them, and pharmaceutical compositions containing them.
    Type: Application
    Filed: April 7, 2008
    Publication date: September 4, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Timo Flessner, Frank-Gerhard Boss, Frank-Thorsten Hafner, Joachim Luithle, Christoph Methfessel, Leila Telan
  • Dermally Applicable Formulations For Treating Skin Diseases in Animals
    Publication number: 20080207670
    Abstract: The invention relates to pharmaceutical formulations comprising a tricyclic compound for the dermal treatment of skin diseases in animals.
    Type: Application
    Filed: September 2, 2005
    Publication date: August 28, 2008
    Applicant: BAYER HEALTHCARE AG
    Inventors: Kirkor Sirinyan, Holger Lehmann
  • Pyrimidine Carboxylic Acid Derivatives and Use Thereof
    Publication number: 20080194598
    Abstract: The present application relates to pyrimidinecarboxylic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, in particular dyslipidaemias and arteriosclerosis.
    Type: Application
    Filed: March 7, 2006
    Publication date: August 14, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Elisabeth Woltering, Arounarith Tuch, Elke Dittrich-Wengenroth, Axel Kretschmer, Lars Barfacker, Marcus Bauser, Peter Ellinghaus, Klemens Lustig, Elisabeth Pook, Olaf Weber
  • 4-amino-substituted pyrimidine derivatives
    Patent number: 7410973
    Abstract: The present invention relates to novel 4-amino-substituted pyrimidine derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of central nervous system diseases.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: August 12, 2008
    Assignee: Bayer Healthcare AG
    Inventors: Achim Feurer, Joachim Luithle, Stephan-Nicholas Wirtz, Gerhard König, Johannes-Peter Stasch, Elke Stahl, Rudy Schreiber, Frank Wunder, Dieter Lang
  • Formulations With Controlled Release Of Active Ingredient
    Publication number: 20080187588
    Abstract: The present invention relates to novel pharmaceutical dosage forms with controlled release of active ingredient which comprise the PDE 5 inhibitor vardenafil and/or pharmaceutically acceptable salts, hydrates, solvates and/or polymorphic forms thereof as active ingredient, and to the production thereof. The invention further relates to the use of these novel pharmaceutical dosage forms as medicaments, and to their use for producing medicaments for the treatment and/or prevention of disorders in humans and animals.
    Type: Application
    Filed: May 10, 2005
    Publication date: August 7, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Susanne Zuleger, Peter Serno, Helmut Haning, Kerstin Pauli, Roland Heinig
  • Antibacterial macrocycles
    Patent number: 7405201
    Abstract: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions comprising them, and their use in the treatment of diseases in humans or animals.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: July 29, 2008
    Assignee: Bayer Healthcare AG
    Inventors: Berthold Hinzen, Heike Brötz-Oesterhelt, Rainer Endermann, Kerstin Henninger, Holger Paulsen, Siegfried Raddatz, Thomas Lampe, Veronika Hellwig, Andreas Schumacher
  • DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH OXYTOCIN RECEPTOR (OXTR)
    Publication number: 20080176234
    Abstract: The invention provides a human OXTR which is associated with lung cancer and colon cancer. The invention also provides assays for the identification of compounds useful in the treatment or prevention of lung cancer and colon cancer.
    Type: Application
    Filed: September 28, 2007
    Publication date: July 24, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Stefan GOLZ, Ulf Bruggemeier, Andreas Geerts
  • Phenyl Acetamides
    Publication number: 20080176898
    Abstract: The present invention relates to phenylacetamides, to a process for their preparation and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, especially of cardiovascular disorders.
    Type: Application
    Filed: April 14, 2005
    Publication date: July 24, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Michael Harter, Frank Wunder, Lars Barfacker, Gunter Karig, Walter Hubsch, Hanna Tinel, Eva-Maria Becker
  • Cinnamic acid amides
    Patent number: 7402683
    Abstract: The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: July 22, 2008
    Assignee: Bayer HealthCare AG
    Inventors: Nina Brunner, Christoph Freiberg, Thomas Lampe, Ben Newton, Michael Otteneder, Josef Pernerstorfer, Jens Pohlmann, Guido Schiffer, Mitsuyuki Shimada, Niels Svenstrup, Rainer Endermann, Peter Nell
  • Reduction of Digestibility of Phosphorus
    Publication number: 20080160163
    Abstract: The present invention relates to novel animal feeds containing lanthanide compounds, as well as to the use of lanthanide compounds for reducing the digestibility of phosphorus contained in animal feeds.
    Type: Application
    Filed: February 21, 2006
    Publication date: July 3, 2008
    Applicant: BAYER HEALTHCARE AG
    Inventors: Bernard Schmidt, Ute Spiecker-Hauser, Dirk Mertin
  • Hetaryloxy-Substituted Phenylamino Pyrimidines as Rho Kinase Inhibitors
    Publication number: 20080139595
    Abstract: The invention relates to hetaryloxy-substituted phenylaminopyrimidines, to a process for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular cardiovascular disorders.
    Type: Application
    Filed: March 30, 2005
    Publication date: June 12, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Hartmut Schirok, Martin Radtke, Joachim Mittendorf, Raimund Kast, Johannes-Peter Stasch, Mark Jean Gnoth, Klaus Munter, Dieter Lang, Santiago Figueroa Perez, Michael Thutewohl, Samir Bennabi, Heimo Ehmke