Patents Assigned to Bayer HealthCare, LLC
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Patent number: 11938093Abstract: A fluid path connector for a medical fluid delivery system, the fluid path connector including a first connector element comprising a body, a first lumen, a first flexible leg, and a second flexible leg, and a second connector element comprising a body defining an undercut, a second lumen, a channel defined in the body, and at least one sealing element positioned within the channel, in which the first flexible leg comprises a first flange and the second flexible leg comprises a second flange, and in which, upon engagement of the first connector element with the second connector element, the first flange and the second flange engage with the undercut of the body of the second connector element to prevent disengagement of the first connector element and the second connector element.Type: GrantFiled: February 18, 2021Date of Patent: March 26, 2024Assignee: BAYER HEALTHCARE LLCInventors: Michael Spohn, Kevin Cowan, James Dedig, John Haury
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Publication number: 20240091158Abstract: The present disclosure relates generally to bilayer tablets comprising a combination of two active pharmaceutical ingredients, and more specifically to bilayer tablets comprising acetylsalicylic acid, pseudoephedrine, and a dissolution aid. The bilayer tablets utilize a combination of granulated and non-granulated acetylsalicylic acid along with a unique distribution of sodium carbonate as a dissolution aid that provide acetylsalicylic acid and pseudoephedrine in a single dosage form having rapid dissolution and long-term storage stability (low degradation). The present disclosure also provides methods of preparing and of using the bilayer tablets.Type: ApplicationFiled: June 22, 2023Publication date: March 21, 2024Applicant: Bayer HealthCare LLCInventor: Harsh MEHTA
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Patent number: 11931555Abstract: A power injector system having a power injector for enabling delivery of fluid in an injection procedure to be performed on a patient may include one or more processors; a first user interface; and a second user interface. The first user interface and the second user interface may be configured to accept a plurality of user inputs associated with control of a plurality of operations of the power injector system and display information associated with the plurality of operations. One of the first user interface and the second user interface may be proximate to the power injector and the other may be remote from the power injector. The one or more processors may be programmed and/or configured to independently control the first user interface and the second user interface based on a first user input and a next user input received from the first user interface and/or the second user interface.Type: GrantFiled: July 28, 2021Date of Patent: March 19, 2024Assignee: BAYER HEALTHCARE LLCInventors: John Volkar, Corey Kemper, Samantha Parker, James Hoon Yoo, Leona Mulcahy, Michael Brooks, Richard Sokolov
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Publication number: 20240082958Abstract: The present disclosure is directed to capsules, for example, softgel capsules for oral administration that have on their surface laser etching that penetrates at least partially into the surface of the capsule, reduces the structural integrity of the capsule while preventing exposure of the interior contents to the outside environment, and increases the rate of release of active ingredients contained within.Type: ApplicationFiled: October 8, 2020Publication date: March 14, 2024Applicants: Bayer HealthCare LLC, Ackley Machine CorporationInventors: Debanjan Das, Reinhard Walter, Javier Zumeta Perez, Alberto Prior Cabanillas, Gerard Meisel, Carlos Figueroa, Mark David Ford, Roland Norman Thurston, Jr.
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Patent number: 11918775Abstract: An assembly for retaining a pressure jacket (134) and a syringe (132) on a fluid injector, the assembly including a base plate (1902) comprising a body (1904); at least a first retaining arm (1910a) and a second retaining arm (1910b) operatively mounted on the body of the base plate, the first retaining arm having a first retaining surface at a distal end thereof and the second retaining arm having a second retaining surface at a distal end thereof, wherein the first retaining surface and the second retaining surface are configured for abutting a distal surface of at least one of the pressure jacket and the syringe; a linkage assembly operatively connected to at least one of the first retaining arm and the second retaining arm, wherein the linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position.Type: GrantFiled: September 9, 2020Date of Patent: March 5, 2024Assignee: BAYER HEALTHCARE LLCInventors: Michael Spohn, Kevin Cowan, Arthur Uber, III, Patrick Campbell, Andrew Osan, John Haury, James Dedig, Andrew Naples, Christopher Scutt, Michael Swantner, Nathaniel Payor
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Patent number: 11923060Abstract: A method is provided for authenticating, and establishing and tracking eligibility of a patient to purchase an over-the-counter (OTC) drug from a retailer, the patient using a client device or terminal and the retailer having a server. The server is configured to redirect the client device or terminal to a backend platform to authenticate the patient, access a storage to search for any information that indicates the patient is ineligible to purchase the OTC drug; and without any information that indicates the patient is ineligible, administer a questionnaire to the patient to assess the eligibility for the OTC drug. And the backend platform redirects the client device or terminal back to the server to complete the online sale of the OTC drug to the patient when the patient is eligible, or cancel the online sale of the OTC drug to the patient when the patient is ineligible.Type: GrantFiled: March 9, 2023Date of Patent: March 5, 2024Assignee: Bayer HealthCare LLCInventors: Rama Penta, Jeffrey Brittain, William Hanisak, Audrey Belkin, Steven Rusche
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Patent number: 11918407Abstract: Described is a method of providing an estimate of radiation dose received by a patient during an imaging scan performed by an imaging system. The method includes receiving patient information about the patient, receiving scan data generated during the imaging scan of the patient by the imaging system, creating a virtual dose model of the patient based upon the patient information and the scan data, receiving a selection of a region of interest of the patient, performing a dose simulation on the virtual dose model of the patient or a portion thereof, and determining, based upon an outcome of the dose simulation, an estimate of the radiation dose received within the region of interest. The imaging scan can be a partial imaging scan of a portion of the patient. Also provided is a system and software for carrying out this method.Type: GrantFiled: April 8, 2019Date of Patent: March 5, 2024Assignee: BAYER HEALTHCARE LLCInventors: David Griffiths, Arthur Uber, Jacob Agris, Ting Lu, Peter Thompson
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Patent number: 11911517Abstract: The present disclosure provides for suspension-based pharmaceutical formulations for cold and flu medications, specifically suspension formulations and soft gel capsule dosage forms having reduced size. The present disclosure also provides methods of preparing the suspensions and soft gel capsule dosage forms.Type: GrantFiled: May 13, 2019Date of Patent: February 27, 2024Assignee: BAYER HEALTHCARE LLCInventors: Javier Zumeta Perez, Blanca Alvarez Maluenda, Maria Pilar Sanz Saiz, Maria Elena Iglesias PiƱeiro, Anthony Bell, Reinhard Walter
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Publication number: 20240058274Abstract: This disclosure is in the field of mini-softgel capsules, particularly softgel capsules containing naproxen salt as an active ingredient. It relates generally to softgel capsules containing high concentration formulations of naproxen sodium.Type: ApplicationFiled: January 10, 2022Publication date: February 22, 2024Applicant: Bayer Healthcare LLCInventors: Blanca ALVAREZ MALUENDA, Maria Elena IGLESIAS PINEIRO, Maria Pilar SANZ SAIZ, Anthony EKPE
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Patent number: 11896352Abstract: A system and method for promoting and safeguarding the wellbeing of patients in relation to a fluid injection may obtain patient data; determine, based on the patient data, an initial risk prediction for a patient for a fluid injection to be administered to the patient, the initial risk prediction including a probability that the patient experiences at least one adverse event in response to the fluid injection; provide, to a user device, before the fluid injection is administered to the patient, the initial risk prediction; determine, after the fluid injection is started, sensor data associated with the patient; determine, based on the sensor data determined after the fluid injection is started, a current risk prediction including a probability that the patient experiences the at least one adverse event in response to the fluid injection; and provide, to the user device, the current risk prediction.Type: GrantFiled: April 30, 2021Date of Patent: February 13, 2024Assignee: BAYER HEALTHCARE LLCInventors: Johannes Anton Thuering, Arthur Uber, III, David Griffiths, Michael McDermott, Charles Lang, Linda Van Roosmalen, Barry Skirble, Adam Czibur, Daniel Moore, Vincenzo Caruso, Brandon Clarke
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Publication number: 20240041778Abstract: This disclosure is in the field of mini-softgel capsules, particularly softgel capsules containing naproxen salt as an active ingredient. It relates generally to softgel capsules containing high concentration formulations of naproxen sodium.Type: ApplicationFiled: August 9, 2023Publication date: February 8, 2024Applicant: Bayer Healthcare LLCInventors: Blanca ALVAREZ MALUENDA, Maria Elena IGLESIAS PINEIRO, Maria Pilar SANZ SAIZ, Anthony EKPE
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Patent number: 11883636Abstract: A fluid injector system has at least one reciprocally operable piston having a piston head, and a plunger engagement mechanism associated with the piston head. The plunger engagement mechanism has a cam sleeve disposed within the piston head and movable relative to the piston head, the cam sleeve having one or more tracks defining a cam surface. The plunger engagement mechanism further has an actuator operatively connected to the cam sleeve for moving the cam sleeve relative to the piston head, and one or more pins disposed within the cam sleeve. The one or more pins are movable within the one or more tracks with movement of the cam sleeve between a first or withdrawn position, wherein the one or more pins are radially withdrawn into the piston head and a second or extended position, wherein the one or more pins protrude radially outward relative to an outer surface of the piston head.Type: GrantFiled: February 25, 2019Date of Patent: January 30, 2024Assignee: BAYER HEALTHCARE LLCInventors: Shahab Taheri, Timothy Newing, Grant Karsten, Aiden Salm, Han Min Thu
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Patent number: 11865323Abstract: A fluid injection system and a fluid verification system for confirming that a syringe, containing a fluid for injection, is fully filled with fluid and neither has free space (i.e., air) near the distal end thereof when the syringe is provided in an upright position nor contains air bubbles. Imaging processing techniques and systems are also provided to determine various injection parameters and to verify the type and certain properties of fluid that is present within a syringe.Type: GrantFiled: February 18, 2021Date of Patent: January 9, 2024Assignee: BAYER HEALTHCARE LLCInventors: Kevin Cowan, Michael Spohn, Michael McDermott
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Patent number: 11865294Abstract: A fluid control valve for use in a fluid delivery system for delivering fluid to a patient includes a valve body defining an internal chamber, a first inlet port for receiving a first inlet tube, a second inlet port for receiving a second inlet tube, an outlet port, and a sliding valve member slidably disposed in the internal chamber. The first inlet tube defines a first inlet lumen axially aligned with the internal chamber. The second inlet tube defines a second inlet lumen axially aligned with the internal chamber. The sliding valve member includes a first sealing end and second sealing end. The sliding valve member is positionable in a first operating state, a second operating state, and a third operating state based on a flow differential between the first inlet lumen and the second inlet lumen.Type: GrantFiled: October 16, 2017Date of Patent: January 9, 2024Assignee: BAYER HEALTHCARE LLCInventors: Michael Spohn, Kevin Cowan, Brian Cain, David Berry, James Fentress, David Orenstein, James Dedig, Barry Tucker
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Patent number: 11857684Abstract: The present disclosure relates generally to bilayer tablets comprising a combination of two active pharmaceutical ingredients, and more specifically to bilayer tablets comprising acetylsalicylic acid, pseudoephedrine, and a dissolution aid. The bilayer tablets utilize a combination of granulated and non-granulated acetylsalicylic acid along with a unique distribution of sodium carbonate as a dissolution aid that provide acetylsalicylic acid and pseudoephedrine in a single dosage form having rapid dissolution and long-term storage stability (low degradation). The present disclosure also provides methods of preparing and of using the bilayer tablets.Type: GrantFiled: November 11, 2021Date of Patent: January 2, 2024Assignee: Bayer HealthCare LLCInventor: Harsh Mehta
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Patent number: 11839751Abstract: An apparatus (300) for suspending air bubbles in a fluid path of a fluid injector system includes an internal chamber (320) having a curved interior wall (322) defined within the housing (310), an inlet fluid pathway in fluid communication with the internal chamber, and an outlet fluid pathway in fluid communication with the internal chamber. The inlet fluid pathway extending into the chamber at a tangent to the curved interior wall, and the outlet fluid pathway spaced from the inlet fluid pathway such that fluid flowing into the internal chamber via the inlet fluid pathway is directed away from the outlet fluid pathway. The internal chamber is configured to create an internal fluid vortex in an injection fluid entering the internal chamber from the inlet fluid pathway, and wherein the internal fluid vortex at least temporarily suspends air bubbles in the fluid in the internal vortex and delays the passage of the air bubbles to the outlet fluid pathway.Type: GrantFiled: June 16, 2021Date of Patent: December 12, 2023Assignee: BAYER HEALTHCARE LLCInventors: Kevin Cowan, James Dedig, Michael Spohn, John Haury
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Patent number: 11826541Abstract: A cap for intake and delivery of a fluid from a syringe is described. The cap includes an outer cap assembly comprising a fluid inlet path and a fluid outlet path and an inner cap assembly configured for insertion into a fluid nozzle of the syringe and to provide selective fluid communication between an interior of a syringe and the fluid inlet path or the fluid outlet path. The outer cap assembly is slidable relative to the inner cap assembly between a first filling position, where the interior of the syringe is in fluid communication with the fluid inlet path, and a second delivery position, where the interior of the syringe is in fluid communication with the fluid outlet path. Syringes including the cap are also described.Type: GrantFiled: September 12, 2018Date of Patent: November 28, 2023Assignee: BAYER HEALTHCARE LLCInventors: Kevin Cowan, Michael Spohn, Barry Tucker, Matthew Walker, James Dedig, James Fentress, Joseph Ranaletta
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Patent number: 11826553Abstract: A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.Type: GrantFiled: September 28, 2021Date of Patent: November 28, 2023Assignee: BAYER HEALTHCARE LLCInventors: Arthur Uber, III, Chelsea Marsh, William Barone, Michael McDermott, Timothy Newing, Michael Spohn, Vince Delbrugge, Ralph Schriver, Kevin Cowan, David Griffiths
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Patent number: D1002840Type: GrantFiled: September 18, 2020Date of Patent: October 24, 2023Assignee: Bayer Healthcare LLCInventors: Kevin Cowan, John Haury
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Patent number: D1003729Type: GrantFiled: April 22, 2020Date of Patent: November 7, 2023Assignee: Bayer Healthcare LLCInventors: Mark Kansburg, Graham Hufton