Patents Assigned to Bayer HealthCare, LLC
  • Patent number: 12002560
    Abstract: A fluid injector system has a controller for operably controlling the injection of contrast and/or saline into a patient. The controller allows a user to program a diagnostic injection procedure having one or more phases according to which the contrast and/or saline will be injected into the patient so as to effect enhancement of a region thereof during an imaging procedure. It further allows the user to program a test injection procedure to be performed prior to the diagnostic injection procedure. The test injection procedure is implementable as: (a) a variable single phase test injection in which the rate at which the saline is to be delivered is selectable prior to and may be varied during performance thereof; and/or (b) a multi-phase test injection in which the rate at which the saline is to be delivered is selectable for each phase of the multi-phase test injection prior to performance thereof.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: June 4, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Corey Kemper, John Volkar, Michael Brooks, Leona Mulcahy
  • Patent number: 11999084
    Abstract: A syringe includes a barrel having a proximal end, a distal end, and a sidewall extending substantially circumferentially between the proximal end and the distal end along a longitudinal axis. The barrel is formed from an injection molding process including aligning a mold die defining an internal shape of the barrel in a molding cavity defining an external shape of the barrel, the molding cavity defined by first and second mold sections. Each mold section includes at least one gate adapted to control the flow of a molding material into the molding cavity. The gates of each mold section are opened to permit the first and second melt streams of molding material to fill the molding cavity surrounding the mold die, where the molding material takes the shape of the molding cavity.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: June 4, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Brian Cain, Matthew Schrauder, Theodore B. Lemke, Randy J. Krell
  • Patent number: 11998718
    Abstract: A plunger for use with a syringe includes a plunger body defining a central longitudinal axis and having a proximal end, a distal end, and a circumferential sidewall connecting the proximal end and the distal end. The plunger further includes at least one retaining member associated with and extending proximally from the plunger body. The at least one retaining member has a first end connected to the plunger body, a second end proximal to the first end and radially and resiliently deflectable relative to the first end, and at least one catch on the second end. A fluid injector system includes a piston having a plunger engagement mechanism configured for interacting with the at least one retaining element of the plunger to releasably engage the plunger for reciprocally driving the plunger within a barrel of the syringe.
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: June 4, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Kevin Cowan, James Dedig, Shahab Taheri, Abhinav Srivastava, Barry Tucker, Michael Swantner, Christopher Capone, Jaroslow Wlodarczyk, Andrew Osan
  • Patent number: 12002203
    Abstract: Described are systems and methods for assessing a likelihood of chronic thromboembolic pulmonary hypertension (CTEPH) within a subject patient based upon an analysis of characteristics indicative of chronic thromboembolic pulmonary hypertension within an imaging study of the subject patient. The systems and methods can identify characteristics of one or more anatomical structures within a cardiac region of the subject patient indicative of CTEPH, characteristics of a pulmonary vasculature of the subject patient indicative of CTEPH, and characteristics of a chronic abnormality in a lung of the subject patient indicative of CTEPH. The systems and methods can assess these characteristics to compute the likelihood of CTEPH within the subject patient.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: June 4, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Karym El Sayed, Henry Hernaez, Nivitha Mahesh, Wei Liao, Franco Fois, Daniel Rechsteiner, Jacob Agris, Mohammad Sedigh Ghamari, Xiangzhen Gao, Prahlad Menon Gopalakrishna
  • Publication number: 20240177820
    Abstract: A method is provided for authenticating, and establishing and tracking eligibility of a patient to purchase an over-the-counter (OTC) drug from a retailer, the patient using a client device or terminal and the retailer having a server. The server is configured to redirect the client device or terminal to a backend platform to authenticate the patient, access a storage to search for any information that indicates the patient is ineligible to purchase the OTC drug; and without any information that indicates the patient is ineligible, administer a questionnaire to the patient to assess the eligibility for the OTC drug. And the backend platform redirects the client device or terminal back to the server to complete the online sale of the OTC drug to the patient when the patient is eligible, or cancel the online sale of the OTC drug to the patient when the patient is ineligible.
    Type: Application
    Filed: February 5, 2024
    Publication date: May 30, 2024
    Applicant: Bayer HealthCare LLC
    Inventors: Rama PENTA, Jeffrey BRITTAIN, William HANISAK, Audrey BELKIN, Steven RUSCHE
  • Publication number: 20240165039
    Abstract: The present disclosure provides for suspension-based pharmaceutical formulations for cold and flu medications, specifically suspension formulations and soft gel capsule dosage forms having reduced size. The present disclosure also provides methods of preparing the suspensions and soft gel capsule dosage forms.
    Type: Application
    Filed: January 24, 2024
    Publication date: May 23, 2024
    Applicant: Bayer Healthcare LLC.
    Inventors: Javier ZUMETA PEREZ, Blanca ALVAREZ MALUENDA, Maria Pilar SANZ SAIZ, Maria Elena IGLESIAS PIÑEIRO, Anthony BELL, Reinhard WALTER
  • Patent number: 11986621
    Abstract: A method and system determine, with a computer system including one or more processors, a plurality of parameters associated with a volume in an object over time in a series of sequence blocks. In a sequence block in the series of sequence blocks, the plurality of parameters are determined as occurring simultaneously in the volume in the object. At least one parameter of the plurality of parameters varies from the sequence block to another sequence block in the series of sequence blocks, and the plurality of parameters include a contrast related parameter associated with a concentration of a contrast agent in the volume in the object over time in the series of sequence blocks. The computer system generates a signal evolution based on the plurality of parameters of the volume in the object over time in the series of sequence blocks, the signal evolution defining the contrast related parameter over time in the series of sequence blocks.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: May 21, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventor: Arthur E. Uber, III
  • Patent number: 11984213
    Abstract: A method, system, and computer program product for peer exchange of data between injection systems. A first injection system may store a plurality of injection control data sets, determine a first subset of the plurality of injection control data sets according to which the first injection system is configured to control delivery of fluid to a patient, provide the first subset of the plurality of injection control data sets for selection of an injection control data set for use in delivering fluid to the patient with the first injection system, and transmit the plurality of injection control data sets to at least one second injection system.
    Type: Grant
    Filed: June 15, 2022
    Date of Patent: May 14, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: John Volkar, Corey Kemper, Srikanth Mruthik, Michael Oklejewski
  • Patent number: 11975172
    Abstract: An engagement mechanism associated with a reciprocally movable piston of a fluid injector is configured for releasably engaging an engagement portion at a proximal end of a rolling diaphragm syringe having a flexible sidewall configured for rolling upon itself when acted upon by the piston. The engagement mechanism has a plurality of engagement elements reversibly and radially movable relative to the engagement portion of the syringe between a first position, where the plurality of engagement elements are disengaged from the engagement portion of the syringe, and a second position, where the plurality of engagement elements are engaged with the engagement portion of the syringe. The engagement mechanism further has a drive mechanism for moving the plurality of engagement elements between the first position and the second position.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: May 7, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Kevin Cowan, Michael Spohn, Adam Steege, Jessie Delgado, Keith Lipford, Chet Larrow, Mariano Mumpower, Danica Gordon
  • Patent number: 11969582
    Abstract: A plunger, a syringe, system, and a method for increasing a seal between a sidewall of a plunger and a sidewall of a syringe are disclosed. The plunger includes a support ring and a cover disposed over and coupled to the support ring. A cavity defining a predetermined volume is defined between the support ring and the cover. The syringe includes a barrel defining an inner wall and the plunger inserted therein.
    Type: Grant
    Filed: June 2, 2022
    Date of Patent: April 30, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Michael Swantner, Michael McDermott
  • Patent number: 11938093
    Abstract: A fluid path connector for a medical fluid delivery system, the fluid path connector including a first connector element comprising a body, a first lumen, a first flexible leg, and a second flexible leg, and a second connector element comprising a body defining an undercut, a second lumen, a channel defined in the body, and at least one sealing element positioned within the channel, in which the first flexible leg comprises a first flange and the second flexible leg comprises a second flange, and in which, upon engagement of the first connector element with the second connector element, the first flange and the second flange engage with the undercut of the body of the second connector element to prevent disengagement of the first connector element and the second connector element.
    Type: Grant
    Filed: February 18, 2021
    Date of Patent: March 26, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Michael Spohn, Kevin Cowan, James Dedig, John Haury
  • Publication number: 20240091158
    Abstract: The present disclosure relates generally to bilayer tablets comprising a combination of two active pharmaceutical ingredients, and more specifically to bilayer tablets comprising acetylsalicylic acid, pseudoephedrine, and a dissolution aid. The bilayer tablets utilize a combination of granulated and non-granulated acetylsalicylic acid along with a unique distribution of sodium carbonate as a dissolution aid that provide acetylsalicylic acid and pseudoephedrine in a single dosage form having rapid dissolution and long-term storage stability (low degradation). The present disclosure also provides methods of preparing and of using the bilayer tablets.
    Type: Application
    Filed: June 22, 2023
    Publication date: March 21, 2024
    Applicant: Bayer HealthCare LLC
    Inventor: Harsh MEHTA
  • Patent number: 11931555
    Abstract: A power injector system having a power injector for enabling delivery of fluid in an injection procedure to be performed on a patient may include one or more processors; a first user interface; and a second user interface. The first user interface and the second user interface may be configured to accept a plurality of user inputs associated with control of a plurality of operations of the power injector system and display information associated with the plurality of operations. One of the first user interface and the second user interface may be proximate to the power injector and the other may be remote from the power injector. The one or more processors may be programmed and/or configured to independently control the first user interface and the second user interface based on a first user input and a next user input received from the first user interface and/or the second user interface.
    Type: Grant
    Filed: July 28, 2021
    Date of Patent: March 19, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: John Volkar, Corey Kemper, Samantha Parker, James Hoon Yoo, Leona Mulcahy, Michael Brooks, Richard Sokolov
  • Publication number: 20240082958
    Abstract: The present disclosure is directed to capsules, for example, softgel capsules for oral administration that have on their surface laser etching that penetrates at least partially into the surface of the capsule, reduces the structural integrity of the capsule while preventing exposure of the interior contents to the outside environment, and increases the rate of release of active ingredients contained within.
    Type: Application
    Filed: October 8, 2020
    Publication date: March 14, 2024
    Applicants: Bayer HealthCare LLC, Ackley Machine Corporation
    Inventors: Debanjan Das, Reinhard Walter, Javier Zumeta Perez, Alberto Prior Cabanillas, Gerard Meisel, Carlos Figueroa, Mark David Ford, Roland Norman Thurston, Jr.
  • Patent number: 11918775
    Abstract: An assembly for retaining a pressure jacket (134) and a syringe (132) on a fluid injector, the assembly including a base plate (1902) comprising a body (1904); at least a first retaining arm (1910a) and a second retaining arm (1910b) operatively mounted on the body of the base plate, the first retaining arm having a first retaining surface at a distal end thereof and the second retaining arm having a second retaining surface at a distal end thereof, wherein the first retaining surface and the second retaining surface are configured for abutting a distal surface of at least one of the pressure jacket and the syringe; a linkage assembly operatively connected to at least one of the first retaining arm and the second retaining arm, wherein the linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: March 5, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Michael Spohn, Kevin Cowan, Arthur Uber, III, Patrick Campbell, Andrew Osan, John Haury, James Dedig, Andrew Naples, Christopher Scutt, Michael Swantner, Nathaniel Payor
  • Patent number: 11923060
    Abstract: A method is provided for authenticating, and establishing and tracking eligibility of a patient to purchase an over-the-counter (OTC) drug from a retailer, the patient using a client device or terminal and the retailer having a server. The server is configured to redirect the client device or terminal to a backend platform to authenticate the patient, access a storage to search for any information that indicates the patient is ineligible to purchase the OTC drug; and without any information that indicates the patient is ineligible, administer a questionnaire to the patient to assess the eligibility for the OTC drug. And the backend platform redirects the client device or terminal back to the server to complete the online sale of the OTC drug to the patient when the patient is eligible, or cancel the online sale of the OTC drug to the patient when the patient is ineligible.
    Type: Grant
    Filed: March 9, 2023
    Date of Patent: March 5, 2024
    Assignee: Bayer HealthCare LLC
    Inventors: Rama Penta, Jeffrey Brittain, William Hanisak, Audrey Belkin, Steven Rusche
  • Patent number: 11918407
    Abstract: Described is a method of providing an estimate of radiation dose received by a patient during an imaging scan performed by an imaging system. The method includes receiving patient information about the patient, receiving scan data generated during the imaging scan of the patient by the imaging system, creating a virtual dose model of the patient based upon the patient information and the scan data, receiving a selection of a region of interest of the patient, performing a dose simulation on the virtual dose model of the patient or a portion thereof, and determining, based upon an outcome of the dose simulation, an estimate of the radiation dose received within the region of interest. The imaging scan can be a partial imaging scan of a portion of the patient. Also provided is a system and software for carrying out this method.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: March 5, 2024
    Assignee: BAYER HEALTHCARE LLC
    Inventors: David Griffiths, Arthur Uber, Jacob Agris, Ting Lu, Peter Thompson
  • Patent number: D1030051
    Type: Grant
    Filed: September 8, 2023
    Date of Patent: June 4, 2024
    Assignee: Bayer Healthcare LLC
    Inventors: Kevin Cowan, John Haury
  • Patent number: D1030052
    Type: Grant
    Filed: September 8, 2023
    Date of Patent: June 4, 2024
    Assignee: Bayer Healthcare LLC
    Inventors: Kevin Cowan, John Haury
  • Patent number: D1031029
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: June 11, 2024
    Assignee: Bayer Healthcare LLC
    Inventors: Michael Swantner, Richard Seman, Kevin Cowan, Arthur Uber, III