Patents Assigned to Bayer
  • Seed treatment apparatus
    Patent number: 11291154
    Abstract: A seed treatment apparatus provides for minimal waste of products for treating seeds, in that it is precisely controllable and automatically adjustable. A volume of seeds to be treated and a flow rate of treatment product for treating the seeds can both be sensed. At least one of the flow rate of the treatment product and the volume of seeds can automatically be adjusted if it is determined that a ratio of the flow rate of treatment product to the volume of seeds is not the same as a predetermined flow rate to volume ratio.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: April 5, 2022
    Assignee: BAYER CROPSCIENCE LP
    Inventors: Greg A. Reineccius, Steven Schulz
  • Ternary herbicide combinations
    Patent number: 11291208
    Abstract: Herbicide combinations comprising an effective amount of components (A), (B) and (C) wherein (A) denotes one or more herbicides selected from the group of compounds of the formula (I) and salts thereof (B) denotes one or more herbicides selected from the group of the compounds of the formula (II) and their salts (C) denotes at least one compound selected from the group consisting of (C-1) thienecarbazone-methyl; (C-2) pyroxsulam; (C-3) halauxifen; (C-4) pinoxaden; (C-5) pyroxasulfone; and/or salts thereof.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: April 5, 2022
    Assignee: Bayer CropScience Aktiengesellschaft
    Inventors: Achim Zoellkau, Dominique Schreiber
  • THE MONOHYDRATE OF ROGARATINIB HYDROCHLORIDE AND SOLID STATES THEREOF
    Publication number: 20220098201
    Abstract: Compound (III) which is the crystalline form of [4-{[4-amino-6-(methoxymethyl)-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2, -f] [1,2,4]triazin-7-yl]methyl}piperazin-2-one hydrochloride] which is the monohydrate, processes for its preparation, pharmaceutical compositions comprising it and its use in the control of disorders, including cancer.
    Type: Application
    Filed: January 27, 2020
    Publication date: March 31, 2022
    Applicants: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft
    Inventors: Jörg GRIES, Johannes PLATZEK, Claus-Christian HÄSELHOFF, Kai LOVIS
  • System and method for syringe fluid fill verification and image recognition of power injector system features
    Patent number: 11285273
    Abstract: A fluid injection system and a fluid verification system for confirming that a syringe, containing a fluid for injection, is fully filled with fluid and neither has free space (i.e., air) near the distal end thereof when the syringe is provided in an upright position nor contains air bubbles. Imaging processing techniques and systems are also provided to determine various injection parameters and to verify the type and certain properties of fluid that is present within a syringe.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: March 29, 2022
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Kevin Cowan, Michael Spohn, Michael McDermott
  • Macrocyclic fluorine substituted indole derivatives
    Patent number: 11286263
    Abstract: The present invention relates to macrocyclic indole derivatives of general formula (I): in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: March 29, 2022
    Assignees: The Broad Institute, Inc., Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft
    Inventors: Steven James Ferrara, Michael H. Serrano-Wu, Chris Lemke, David McKinney, Mark Fitzgerald, Christopher Nasveschuk, Kiel Lazarski, Laura Furst, Guo Wei, Patrick Ryan McCarren, Kai Thede, Anne Mengel, Clara Christ, Joachim Kuhnke, Sarah Anna Liesa Johannes, Philipp Buchgraber, Ulrich Klar, Ulrike Sack, Stefan Kaulfuss, Amaury Ernesto Fernandez-Montalvan, Nicolas Werbeck, Ursula Mönning
  • PHARMACEUTICAL COMBINATION OF ANTI CEACAM6 AND TIM3 ANTIBODIES
    Publication number: 20220089721
    Abstract: The present disclosure relates to combinations of at least two components, component A and component B, component A being anti-CEACAM6 antibody TPP-3310 and component B being an anti-TIM-3 antibody, preferentially cobolimab, MBG-453, BMS-986258, Sym-023, LY-3321367 or INCAGN-2390.
    Type: Application
    Filed: December 12, 2019
    Publication date: March 24, 2022
    Applicants: Bayer Aktiengesellschaft, Deutsches Krebsforschungszentrum
    Inventors: Jrög WILLUDA, Mark TRAUTWEIN, Rienk OFFRINGA, Hans-Henning BÖHM, Philipp BECKHOVE
  • RECRUITING OF PATIENTS FOR MEDICAMENT STUDIES
    Publication number: 20220093219
    Abstract: The present invention relates to the recruiting of patients for one or more medicament studies. The subjects of the present invention are a method, a system and a computer program product for recruiting patients for one or more medicament studies with the aid of an individual identification feature that is applied to the packaging of a medicament.
    Type: Application
    Filed: January 13, 2020
    Publication date: March 24, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventor: Christian Johannes MÜLLER
  • 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF
    Publication number: 20220089591
    Abstract: The present application relates to novel 7-substituted 1-arylnaphthyridine-3-carboxamides, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prevention of diseases, and to their use for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders and/or renal disorders.
    Type: Application
    Filed: January 28, 2021
    Publication date: March 24, 2022
    Applicants: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft
    Inventors: Henrik TELLER, Alexandros VAKALOPOULOS, Melissa BOULTADAKIS ARAPINIS, Alexander STRAUB, Hanna TINEL, Markus BRECHMANN, Matthias Beat WITTWER, Maximillian Andreas KULLMANN, Till FREUDENBERGER, Thomas MONDRITZKI, Tobias MARQUARDT
  • Method for controlling fluid accuracy and backflow compensation
    Patent number: 11278853
    Abstract: A method for controlling fluid ratio accuracy during a dual flow injection with a powered injection system is described.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: March 22, 2022
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Ralph H. Schriver, Andreas Maihoefer, James A. Dedig, Michael A. Spohn, Herbert M. Grubic, Michael J. Swantner, Adam Caruso
  • Process for preparing benzothiophen-2yl boronate
    Patent number: 11274110
    Abstract: A process for preparing the benzothiophen-2-yl boronate of formula (VI) which serves as an intermediate for production of medicaments and for production of medicaments for treatment and/or prophylaxis of proliferative disorders, such as cancer and tumor diseases.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: March 15, 2022
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Jörg Gries, Johannes Platzek
  • 2-(het)aryl-substituted condensed bicyclic heterocycle derivatives as pest control agents
    Patent number: 11274097
    Abstract: The invention relates to novel compounds of the formula (I) in which the R1, R2a, R2b, R3, A1, A2, A3, A4, A5 and n radicals are each as defined above, to the use thereof as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for preparation thereof.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: March 15, 2022
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Ruediger Fischer, Bernd Alig, Kerstin Ilg, Olga Malsam, Ulrich Goergens, Andreas Turberg, Jun Li, Sergey Zhersh, Alexander Arlt
  • AN ANIMAL CAPTURE SYSTEM
    Publication number: 20220071193
    Abstract: An animal trap system comprises a cage, a door, a switch system, a transmitter, a proximity signal sensor, and a proximity signal emitter. When the door is in a closed position, the door is configured to block the opening of the cage to prevent exit of the animal. When the door is in the open position the proximity signal emitter is at a position such that a magnitude of a proximity signal emitted by the proximity signal emitter and sensed by the proximity signal sensor is configured to maintain the transmitter in a non-transmitting mode. When the door is in the closed position the proximity signal emitter is at a position such that the magnitude of the proximity signal emitted by the proximity signal emitter and sensed by the proximity signal sensor is configured to cause the transmitter to transmit a signal that the cage is occupied.
    Type: Application
    Filed: February 6, 2020
    Publication date: March 10, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Gilbert SPICA, Renaud PAUMELIN
  • COMPOSITIONS AND METHODS FOR CANCER EXPRESSING PDE3A OR SLFN12
    Publication number: 20220071995
    Abstract: The present invention features improved methods of identifying patients having cancer (e.g., melanoma, adenocarcinoma, lung, cervical, liver or breast cancer) using biomarkers (e.g., PDE3A, SLFN12) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention (e.g., DNMDP, zardaverine, and anagrelide).
    Type: Application
    Filed: November 18, 2021
    Publication date: March 10, 2022
    Applicants: The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc., Bayer Pharma Aktiengesellschaft
    Inventors: Luc De Waal, Matthew Meyerson, Heidi Greulich, Monica Schenone, Alex Burgin, Xiaoyun Wu, Ulrike Sack
  • METHOD FOR TRANSFERRING A BATCH PRODUCTION PROCESS TO A CONTINUOUS PRODUCTION PROCESS
    Publication number: 20220073560
    Abstract: Described herein is a method for transferring of batch production process for a monoclonal antibody to a continuous production process for the same monoclonal antibody.
    Type: Application
    Filed: January 8, 2020
    Publication date: March 10, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Bastian BUDDE, Peter SCHWAN, Sven-Oliver BORCHERT, Benjamin MAISER, Sven CLASSEN, Jürgen LENZ, Laura DAVID, Martin LOBEDANN
  • INFORMATION PROCESSING DEVICE, AND INFORMATION PROCESSING SYSTEM
    Publication number: 20220076014
    Abstract: The present disclosure makes it possible to more accurately estimate information relating to crop infection, on the basis of more appropriate cultivation information. Provided is an information processing device comprising: a feature quantity conversion unit that generates a feature quantity by performing a feature quantity conversion of at least one of piece of information among information pieces relating to three factors causing disease in crops, namely a primary cause, a predisposition and an inducement; and an estimation unit that estimates crop infection information on the basis of an infection estimation model which is used to estimate infection information relating to infection of the crop, which is generated on the basis of a machine-learning algorithm, and which uses as input the information relating to the three factors, including the feature quantity.
    Type: Application
    Filed: October 10, 2019
    Publication date: March 10, 2022
    Applicant: Bayer CropScience K.K.
    Inventor: Satoshi ITO
  • Fungicidal oxadiazoles
    Patent number: 11266147
    Abstract: The present invention relates to heterocyclylaminophenyloxadiazole and derivatives thereof that may be used and as fungicides.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: March 8, 2022
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Anne-Sophie Rebstock, Sebastien Naud, Stephane Brunet, Mathieu Gourgues, Harald Jakobi, Andreas Goertz, Emmanuelle Hilt, Sophie Ducerf
  • Use of chymase inhibitors for the treatment of endometriosis, post operative fibrosis and diseases which are characterized by fibrosis formation
    Patent number: 11266646
    Abstract: The present application relates to the use of bicyclic-substituted uracil derivatives, alone or in combinations with other active ingredients for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of inflammatory and fibrotic disorders, for the treatment of endometriosis, of endometriosis-associated fibrosis, of adenomyosis and of pain associated with an endometriosis disorder and also of postoperative peritoneal fibrosis and adhesion formation.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: March 8, 2022
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Michaele Peters, Markus Koch, Thomas Zollner
  • AN AERIAL VEHICLE
    Publication number: 20220061303
    Abstract: An aerial vehicle includes a liquid chemical tank, at least one spray unit, a plurality of sensors, a processing unit, and an output unit. The processing unit is configured to generate a spray record for an environment within which the aerial vehicle is operating, the spray record comprising: information over a time period of at least one spray condition relating to one or more of the at least one spray unit for the aerial vehicle operating within the environment over the time period, the determined air movement direction relative to the projection of the fore-aft axis onto the ground over the time period, and the determined air movement speed relative to the ground over the time period. The output unit is configured to output the spray record.
    Type: Application
    Filed: January 15, 2020
    Publication date: March 3, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventor: Andrew Charles CHAPPLE
  • SYSTEM AND METHOD FOR PREDICTING QUALITY OF A CHEMICAL COMPOUND AND/OR OF A FORMULATION THEREOF AS A PRODUCT OF A PRODUCTION PROCESS
    Publication number: 20220068440
    Abstract: The present disclosure generally relates to the field of model-based quality prediction of a chemical compound-and/or of a formulation thereof as the outcome of a production process comprising more than one sub-process. It further relates to a solution for root cause analysis of variations of one or more quality attributes of said product or formulation thereof.
    Type: Application
    Filed: September 17, 2019
    Publication date: March 3, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Thomas MRZIGLOD, Lynn WÜRTH, Tom MAES, Kai Christopher WELLNER, Stephan TOSCH, Christian BOCK
  • AN AERIAL VEHICLE
    Publication number: 20220066470
    Abstract: An aerial vehicle includes a liquid chemical tank, at least one spray unit, at least one actuator, a plurality of sensors, and a processing unit. The processing unit is configured to determine an air movement direction relative to a projection of the fore-aft axis onto the ground and determine an air movement speed relative to the ground, the determination comprising utilization of the speed of the aerial vehicle, the air movement direction relative to the aerial vehicle with respect to the fore-aft axis of the aerial vehicle and the air movement speed relative to the aerial vehicle. The processing unit is configured to control at least one flying operation of the aerial vehicle and/or control the at least one actuator.
    Type: Application
    Filed: January 15, 2020
    Publication date: March 3, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventor: Andrew Charles CHAPPLE