Abstract: The present invention relates to a method of reducing crop damage by treating the seed of the crop with the safener before sowing. This can be done in addition to the use of crop protection combinations/compositions, in particular herbicide/safener combinations and compositions comprising thereof, which are highly suitable to protect crops from herbicide damage in pre- and post-emergence treatments.

Abstract: The present invention relates to novel active compound combinations comprising at least one known compound of the formula (I) and at least one further active compound, which combinations are highly suitable for controlling animal and microbial pests such as unwanted insects and/or unwanted acarids and/or unwanted nematodes.

Abstract: A system for patient imaging is provided. The system includes an imaging system and a parameter generator to determine parameters of at least a first phase of an injection procedure. The imaging system includes a scanner that has at least one x-ray tube. The parameter generator is programmed to determine at least one of the parameters on the basis of a voltage to be applied to the at least one x-ray tube during an imaging procedure. A method of controlling an injector system is also provided, and the method includes determining injection parameters, at least one of which is determined on the basis of a voltage to be applied to an x-ray tube during the imaging procedure, as well as controlling the injector system at least in part on the basis of the determined injection parameters.

Abstract: The present invention relates to combinations of: component A: one or more 2,3-dihydroimidazo[1,2-c]quinazoline compounds of general formula (A1) or (A2) as defined herein, or a stereoisomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof; and component B: one or more ATR kinase inhibitor(s) as defined herein, or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof; and, optionally, component C: one or more further pharmaceutical agent(s); and, optionally, in which either or both of components A and B in any of the above-mentioned combinations are in the form of a pharmaceutical composition which is ready for use to be administered simultaneously, concurrently, separately or sequentially. The components may be administered independently of one another by the oral, intravenous, topical, local installations, intraperitoneal or nasal route.

Abstract: The present invention relates to: • combinations of: * a component A: which is a PI3K kinase inhibitor, such as copanlisib, or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, or a salt thereof, in particular a physiologically acceptable salt, or a mixture of same, for example; * a component B: which is an androgen receptor antagonist, such as darolutamide or enzalutamide for example; and, optionally, * one or more pharmaceutical agents C; in which optionally either or both of said components A and B are in the form of a pharmaceutical formulation which is ready for use to be administered simultaneously, concurrently, separately or sequentially; • use of such combinations: * in the treatment or prophylaxis of a cancer, particularly prostate cancer, or * for the preparation of a medicament for the treatment or prophylaxis of a cancer, particularly prostate cancer; • methods of treatment or prophylaxis of a cancer, particularly prostate cancer, in a subject, comprising administering to said subject

Abstract: The disclosure is generally directed to methods for screening, identifying, and producing microorganisms capable of imparting beneficial properties to plants. In some aspects, improved plant-associated soil microorganisms are generated by experimental evolution using a plant root exudate or root exudate compound.

Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

Abstract: The present invention relates to a method of treating seed, comprising applying at least one plant treatment agent to said seed; and applying a dry formulation comprising/consisting of spores of P. bilaii and talc powder to said seed. The invention furthermore relates to a formulation for use in seed treatment comprising spores of P. bilaii and talc powder, seed treated with such formulation and methods of improving applicability and quality of P. bilaii spores and methods of improving plant growth, plant health or plant vigor.

Abstract: The present invention relates to a method for preparing substituted 4-aminoindane derivatives of the general formula (I) by rearrangement of compounds of the formula (II) in HF, wherein R1, R2, R3, R4, and R5 have the definitions as specified in the description.

Abstract: The present invention relates to alkynyl-substituted N-phenylpyrrolidine-2,4-diones according to the general formula (I) or agrochemically acceptable salts thereof, where X=C1-C4-alkyl, C1-C4-haloalkyl or C3-C6-cycloalkyl, Y=C1-C4-alkyl or C3-C6-cycloalkyl, R1=hydrogen, C1-C6-alkyl, or C3-C6-cycloalkyl, R2=hydrogen or methyl, R3=C1-C6-alkyl or C1-C6-alkoxy-C2-C6-alkyl, G=hydrogen, a cleavable group L or a cation E. The invention further relates to a herbicidal composition comprising a compound of the general formula (I) and to the use of the compounds according to the invention for controlling weeds and weed grasses in crops of useful plants.

Abstract: The present invention relates to a product planning apparatus. A processing unit of the product planning apparatus is provided with a plurality of orders of a product, wherein the plurality of orders is formed from open orders and shipped orders. The processing unit is provided with a stock level of the product held in stock. The processing unit determines an open demand of the product to be received, wherein the determination comprises utilization of the shipped orders, open orders and a total forecast number of the product to be received. The processing unit determines a net demand of the product to be received, wherein the determination comprises utilization of the open orders, open demand and the stock level. The processing unit determines a production plan, wherein the determination comprises utilization of the net demand.

Abstract: The present invention includes name compounds of general formula (I): (I) in which R1, R2, R3 and R4 are as defined herein, methods for their preparation, pharmaceutical compositions and combinations comprising said compounds, and their use for the treatment of hyperproliferative diseases.

Abstract: The present disclosure relates to the sensor based observation of arthropods in a region where plants grow. The subject matter of the present disclosure is a device, system, method and computer program product for the sensor based observation of arthropods, by means of a camera.

Abstract: The present invention relates to novel substituted 1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.

Abstract: An apparatus for dispensing a foodstuff a heating block (59) having a top side (60) and a bottom side (61), the bottom side (61) being complementary to a portion of the cylinder (11), the heating block (59) being removable from the housing (16) and from the container (1).

Abstract: The present invention relates to stimulators and activators of soluble guanylate cyclase in combination with an inhibitor of neutral endopeptidase and/or angiotensin AII antagonists and the use thereof for the treatment and/or prophylaxis of cardiovascular disorders, for example heart failure with preserved ejection fraction or heart failure with reduced ejection fraction, renal disorders, for example chronic kidney failure, urological disorders, lung disorders, disorders of the central nervous system, for regulation of cerebral perfusion, for example in the event of vascular cerebral states of dementia, for the treatment and/or prophylaxis of fibrotic disorders and other disease symptoms (e.g. end organ damage affecting the brain, kidney or heart).

Abstract: Methods and compositions for controlling undesired vegetation in animal grazelands.

Abstract: The present invention relates to ?2-Adrenoceptor subtype C (alpha-2C) antagonists, in particular aryl piperazines of formula (I) for the use in a method for the treatment and/or prophylaxis of sleep-related breathing disorders, preferably obstructive and central sleep apneas and snoring.

Abstract: The present invention relates to a process for producing compounds of formula (I) in which R1, A, X and Z are as defined in the description by reaction of compounds of formula (II) or salts thereof with 2-chloro-5-chloromethylpyridine in a nonpolar aliphatic or aromatic solvent, preferably in the presence of a phase transfer catalyst.

Abstract: The use of specific active substances, alone or in combination, for controlling virus infections in plants and a method for using said specific active substances for controlling said virus infections in the field of plant protection and the protection of materials are disclosed.