Abstract: This invention relates to novel phenylbenzamides of the formula (I) in which R1 represents trifluoromethyl, chlorine, bromine or iodine and R2 represents hydrogen, methyl or ethyl, to a process for preparing these substances and their use for controlling unwanted microorganisms, and to novel intermediates and their preparation.

Abstract: The application claims a method for treating hypertension by administering an effective amount of a compound of the formula (I) wherein the variable groups are as defined in the specification and claims. These 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.

Abstract: Reagents that regulate human transmembrane serine protease activity and reagents that bind to human transmembrane serine protease gene products can be used to regulate extracellular matrix degradation. Such regulation is particularly useful for treating COPD, metastasis of malignant cells, tumor angiogenesis, inflammation, atherosclerosis, neurodegenerative diseases, and pathogenic infections.

Abstract: A thermoplastic molding composition comprising polycarbonate and at least one aromatic formal is disclosed. The formal conforms to The composition that is characterized by its reduced water uptake, is useful especially for the production of optical data carriers, such as compact discs.

Abstract: A gasket (1) having a reversibly compressible lower portion (17), and an upper portion (14) having at least one upwardly extending extension, is described. The upper portion (14) of the gasket (1) includes a first (34) and optionally a second (37) upwardly extending extension, each having an exterior surface (43, 55). The first and second extensions of the upper portion each have a vertical center line (49, 58) that resides over (or extends through) an underlying exterior longitudinal groove (73, 76) of the lower portion, such that when the gasket is compressed along its vertical center axis (23) a force (79, 82) is exerted laterally outward along (or through) the exterior surfaces of the upwardly extending extensions. The force exerted laterally outward along the exterior surface of an upwardly extending extension serves to maintain a seal (214, 217) formed by abutment of the exterior surface of the extension with a separate surface (e.g.

Abstract: Novel benzenedicarboxamides of the formula (I) wherein X represents hydrogen, halogen atom, nitro, C1-6alkylsulfonyloxy, C1-6alkylsulfinyl, C1-6alkylsulfenyl or C1-6alkylsulfonyl, R1 represents C1-6alkyl, C1-6alkylthio-C1-6alkyl, or C1-6alkyl, m represents 0 or 1, A represents O, S, SO, SO2, CH2 or CH(CH3), and Q represents a 5- or 6-membered heterocyclic group that contains at least one hetero atom selected from the group consisting of N, O and S and can be optionally substituted; processes for their preparation, their intermediates and their use as insecticides.

Abstract: The invention relates to novel pyrimidothienoindazoles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.

Abstract: The invention provides a human KLK3 which is associated with the endocrine system and hormone disorders, cardiovascular disorders, metabolic diseases, cancer disorders, neurological disorders, urological disorders and reproduction disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of endocrine system and hormone disorders, cardiovascular disorders, metabolic diseases, cancer disorders, neurological disorders, urological disorders and reproduction disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of KLK3 as well as pharmaceutical compositions comprising such compounds.

Abstract: The invention relates to novel 2-ethyl-4,6-dimethylphenyl-substituted spirocyclic tetramic acid derivatives of the formula (I) in which A, B and G are as defined above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides, and also to selective herbicidal compositions comprising firstly the 2-ethyl-4,6-dimethylphenyl-substituted spirocyclic tetramic acid derivatives of the formula (I) (where G may also be hydrogen) and secondly at least one crop plant compatibility-improving compound.

Abstract: The invention relates to novel 2,4,6-phenyl-substituted cyclic ketoenols of the formula (I), in which CKE, W, X and Y are as defined above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides, and also to selective herbicidal compositions comprising firstly the 2,4,6-phenyl-substituted cyclic ketoenols and secondly at least one compound which improves crop plant tolerance.

Abstract: Stress tolerance in plants and plant cells is achieved by using nucleotide sequences encoding enzymes involved in the NAD salvage synthesis pathway and/or the NAD de novo synthesis pathway e.g. for overexpression in plants.

Abstract: The invention relates to the use of PDE 5 inhibitors, and especially of known 2-phenyl-substituted imidazotriazinone derivatives for producing medicaments for the treatment of symptoms that can be treated by increasing cGMP levels in certain tissues, such as acute myocardial infarction and damage caused by reperfusion, various symptoms in the female and male reproductive system and urogenital tract, gastrointestinal diseases, damage caused by diabetes, and liver failure.

Abstract: The present invention relates to insecticidal mixtures of chloronicotinyl insecticides of the formula (I) in which R1 represents C1-C5-alkyl, R2 represents hydrogen or C1-C5-alkyl or R1 and R2 together represent —CH2—CH2—; —CH2—CH2—CH2— or X represents an NH group, NCH3 group or represents sulphur, Y represents nitrogen or a CH group and Z represents cyano or nitro, with one or more of the synergists mentioned in the description.

Abstract: A description is given of 4-(4-trifluoromethylpyrazolyl)pyrimidines of the formula (I) and of their use as herbicides. In this general formula (I), R1, R2, R3 and R4 are various radicals and Y is an aromatic or heteroaromatic radical.

Abstract: The present invention relates to a process for the production of mixtures of di- and polyamines of the diphenylmethane series (MDA) containing less than 1,000 ppm of water and less than 200 ppm of aniline by reaction of aniline and formaldehyde in the presence of acid catalysts and subsequent separation of the acid catalyst and subsequent distillative separation of water and aniline in an at least a two-stage distillation including a flash evaporation and subsequent cooling.

Abstract: Macrocyclic pyrimidine derivatives of general formula I in which R1 to R5, X, Y, A, B, m and n have the meanings that are contained in the description, as inhibitors of the cyclin-dependent kinase, their processes for production as well as their use as medications for treating various diseases are described.

Abstract: The present invention relates to derivatives of 9-keto spinosyns, which are substituted by a ?N—(O, NH or NRx)—Ry moiety in the C-9 position, to methods for their manufacture, and to their use for controlling animal pests.

Abstract: A cotton cultivar designated Acala ULTIMA EF is disclosed. The invention relates to the seeds of cotton cultivar Acala ULTIMA EF, to the plants and plant parts of cotton Acala ULTIMA EF and to methods for producing a cotton plant produced by crossing the cultivar Acala ULTIMA EF with itself or another cotton variety. The invention further relates to hybrid cotton seeds and plants produced by crossing the cultivar Acala ULTIMA EF with itself or with another cotton cultivar.

Abstract: A device for determining the residual liquid content of solids cakes in a centrifuge basket. The device includes two electrodes protruding through a wall of the basket and into the solids cake; a conductivity or capacitance measuring device (13) measuring the conductivity of the solids cake between the electrodes; and evaluation and control units contactlessly receiving data from the measuring device to affect the operation of the centrifuge.

Abstract: This invention relates to triazolopyrimidines-of the formula in which R1, R2, R3, R4 and X are as defined in the disclosure, to a process for preparing these compounds and to their use for controlling unwanted microorganisms.