Patents Assigned to Bayer
  • Patent number: 7045573
    Abstract: Isocyanate-functional polyurethane prepolymers and aqueous dispersions therefrom which are useful for the production of flat materials having excellent resistance to alcoholic solvents are described. The prepolymers are prepared by reacting: A) an isocyanate selected from the group consisting of i) an aliphatic and/or a cycloaliphatic isocyanate, ii) a mixture of an aromatic isocyanate and an aliphatic and/or a cycloaliphatic isocyanate, B) a di- or polyhydroxy compound having a number average molecular weight of from 700 to about 16,000, and C) optionally, a dihydroxy and/or polyhydroxyl compound having a number average molecular weight of less than 700, with the provisos that a) at least one of components A), B or C) has a functionality of more than 2 and b) if both component A) and component B) are difunctional, component C) cannot be a trihydroxy component of the formula: R—(OH)3 ?where R is a saturated straight chain or branched chain aliphatic group of from 2 to 8 carbon atoms.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: May 16, 2006
    Assignees: Bayer MaterialScience LLC, Bayer MaterialScience AG
    Inventors: Eduard Mayer, Thomas Muenzmay, Yuliya Berezkin, Poli C. Yu, Richard R. Roesler, Mary A. Crisci
  • Publication number: 20060100246
    Abstract: This invention is to provide a process for producing 2-amino-4,6-disubstituted nicotinic acid ester analogs and salts thereof, comprising the reaction shown by the following scheme. The ester analogs can be prepared in one pot, and in good yield by using tertiary alkyl cyanoacetate. Furthermore, the method is useful for preparing derivatives of various analogs of the ester, e.g. alkyl substituted and aryl substituted analogs.
    Type: Application
    Filed: September 30, 2005
    Publication date: May 11, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Toshiki Murata, Masaomi Umeda, Sachiko Sakakibara, Takashi Yoshino, Hiroki Sato, Tsutomu Masuda, Yuji Koriyama, Mitsuyuki Shimada, Takuya Shintani, Hiroshi Kadono, Timothy Lowinger, Karl Ziegelbauer, Kinji Fuchikami, Hiroshi Komura
  • Publication number: 20060100207
    Abstract: The invention relates to novel dihydropyridinone derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
    Type: Application
    Filed: August 18, 2003
    Publication date: May 11, 2006
    Applicant: Bayer Healthcare AG
    Inventors: Heike Gielen-Haertwig, Volkhart Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allerheiligen, Leila Telan, Lars Barfacker, Jorg Keldenich, Mary Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • Publication number: 20060099598
    Abstract: Encephalotoxin produced by activated mononuclear phagocytes is present in individuals having neurological disease including neurodegenerative and neuro-inflammatory diseases, such as Azlheimer's disease (AD), HIV-1-associated dementia (HAD), Creutzfeld-Jakob disease, Mild Cognitive Impairment, prion disease, mild congnitive/motor dysfunction, acute stroke, acute trauma, or neuro-AIDS. Biochemical detection of encephalotoxin according to the methods of the invention will allow diagnosis of neurological disease in early, presymptomatic stages, thereby allowing early intervention in disease progression as well as identification of subjects or populations at risk for developing neurodegenerative disease. The methods of the invention also provide a mechanism for monitoring progression and treatment of neurological disease.
    Type: Application
    Filed: January 27, 2004
    Publication date: May 11, 2006
    Applicant: Bayer College of Medicine
    Inventor: Dana Giulian
  • Publication number: 20060100222
    Abstract: The invention relates to the use of selective phosphodiesterase 9A (PDE9A) inhibitors for producing medicaments for improving perception, concentration, cognitive processes, learning and/or memory.
    Type: Application
    Filed: August 11, 2003
    Publication date: May 11, 2006
    Applicant: Bayer Healthcare AG
    Inventors: Frank-Gerhard Boss, Christina Erb, Martin Hendrix, Marja Kampen, Frank Wunder
  • Patent number: 7041725
    Abstract: Modified polyurethanes based on polyurethane reactive systems composed of at least one organic polyisocyanate and a polyol formulation, which additionally contains at least one polymer modifier and at least one filler are prepared. These modified polyurethanes are useful in the production of electroplated/metallized molded articles.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: May 9, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Detlef Arntz, Eduard Mayer, Helmut Meyer
  • Patent number: 7041781
    Abstract: Homo- and/or copolymers of one or more ethylenically unsaturated monomers, suitable for the preparation of molded articles that feature improved properties, especially improved fracture properties, heat stability and notched impact strength are disclosed. These homo- and/or copolymers are characterized in that they contain less than 400 particles per m2 of surface area with a diameter greater than 200 ?m.
    Type: Grant
    Filed: May 21, 2001
    Date of Patent: May 9, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Alfred Eitel, Michael König, Dorothy Rose, Hans-Bernhard Hauertmann, Heinrich Alberts, Dieter Wittmann
  • Patent number: 7041776
    Abstract: The invention relates to a method of producing polyisocyanates of the diphenylmethane series including the steps of a) reacting aniline and formaldehyde in the presence of HCl to provide a product mixture containing polyamines of the diphenylmethane series, HCl, aniline and water; b) removing excess aniline and water by distillation to provide a product mixture comprising polyamines of the diphenylmethane series, HCl, no more than 10 wt. % aniline based on the polyamines, and no more than 5 wt. % water based on the polyamines; and c) phosgenating the product mixture in (b).
    Type: Grant
    Filed: September 26, 2003
    Date of Patent: May 9, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Daniel Koch, Hans-Georg Pirkl, Torsten Hagen, Stefan Wershofen
  • Patent number: 7041767
    Abstract: The invention pertains to polysiloxane polymers, methods for their production, and their use as wash resistant hydrophilic softeners.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: May 9, 2006
    Assignee: GE Bayer Silicones GmbH & Co. KG
    Inventors: Horst Lange, Roland Wagner, Anita Witossek, Karl-Heinz Stachulla, Siegfried Teuber, Albert Schnering, Annette Möller, Martin Kropfgans, Karl-Heinz Sockel, Don Firstenberg
  • Patent number: 7041760
    Abstract: The present invention relates to a process for producing polymers containing repeating units derived from at least one isoolefin monomer, optionally repeating units derived from at least one multiolefin monomer and optionally further copolymerizable monomers in the presence of a zinc compound and optionally an organic halide activator.
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: May 9, 2006
    Assignee: Bayer Inc.
    Inventors: Manfred Bochmann, Shaun Garratt
  • Patent number: 7041646
    Abstract: The invention provides polypeptides that act both as an agonist of the GLP-1 receptor and an antagonist of the glucagon receptor. Such polypeptides are useful for treating individuals with type 2 diabetes or other metabolic disorders.
    Type: Grant
    Filed: January 16, 2003
    Date of Patent: May 9, 2006
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Clark Pan, James Whelan, Kevin B. Clairmont
  • Patent number: 7041768
    Abstract: The present invention relates to novel one-component polyurethane systems including one or more organic and/or inorganic compounds of vanadium in which the vanadium has an oxidation state of at least +4, to their preparation and use for preparing paints, inks and adhesives.
    Type: Grant
    Filed: February 20, 2004
    Date of Patent: May 9, 2006
    Assignee: Bayer Materialscience AG
    Inventors: Christoph Gürtler, Jan Mazanek, Joachim Petzoldt, Heinz Schmidt, Stephan Nowak
  • Patent number: 7041858
    Abstract: The present invention is directed to a process for the isothermal nitration of aromatic organic compounds, wherein an aromatic organic compound is brought into contact and reacted with a mixture of sulfuric acid and nitric acid. The mixture of sulfuric acid and nitric acid, and the aromatic organic compound are brought into contact with each other through a mixing nozzle which comprises a substantially cylindrical tubular reactor and an annular gap which surrounds the tubular reactor. The aromatic organic compound flows through the tubular reactor, and the mixture of sulfuric acid and nitric acid flows through the annular gap, and they are mixed together upon emerging from the tubular reactor and the annular gap, wherein the ratio of the average rates of flow of the aromatic organic compound in the tubular reactor, and of the mixture of sulphuric acid and nitric acid in the annular gap ranges from 0.5:1 to 10:1.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: May 9, 2006
    Assignees: Bayer MaterialScience LLC, Bayer MaterialScience AG
    Inventors: Juergen Muennig, Bernd Pennemann, Dietmar Wastian, Volker Michele, Jesse Caravaggio, John F. Gisch, Jr.
  • Patent number: 7041852
    Abstract: The present invention relates to a process for preparing perfluoroalkylanilines and to their use for preparing active ingredients, in particular for agrochemicals.
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: May 9, 2006
    Assignee: Bayer Chemicals AG
    Inventors: Albrecht Marhold, Axel Pleschke
  • Patent number: 7041354
    Abstract: Optical data carrier comprising a preferably transparent substrate which may, if desired, have previously been coated with one or more reflection layers and to whose surface a light-writeable information layer, if desired one or more reflection layers and if desired a protective layer or a further substrate or a covering layer have been applied, which can be written on or read by means of blue, red or infrared light, preferably laser light, where the information layer comprises a light-absorbent compound and, if desired, a binder, characterized in that at least one cyanine dye is used as light-absorbent compound.
    Type: Grant
    Filed: September 29, 2004
    Date of Patent: May 9, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Horst Berneth, Friedrich-Karl Bruder, Wilfried Haese, Rainer Hagen, Karin Hassenrück, Serguei Kostromine, Peter Landenberger, Rafael Oser, Thomas Sommermann, Josef-Walter Stawitz, Thomas Bieringer
  • Patent number: 7041732
    Abstract: A compatible blend of polycarbonate resin with a vinyl (co)polymer blending partner is disclosed. The preparation of inventive blend comprise reactive blending of polycarbonate, a vinyl (co)polymer and a novel compatibilizer in the presence of a transesterification catalyst and under conditions of time and temperature designed to promote transesterification. The compatibilizer is the polymerized reaction product of at least one vinyl monomer that contains no hydroxy groups and a hydroxyl containing monomer conforming to (I) where R denotes H or C1–C4 alkyl, R1 denotes H, Cl, Br, C1–C4 alkyl, cyclohexyl, or C1–C4 alkoxy, a is 0 or 1, b is 0 or 1, c is 0 or 1, n is an integer of 0 to 4 and X is an OH group. The compatible blends of the invention are characterized by their improved properties.
    Type: Grant
    Filed: December 8, 2003
    Date of Patent: May 9, 2006
    Assignee: Bayer MaterialScience LLC
    Inventors: Daniel H. Bolton, Pierre Moulinie, David M. Derikart, Nicanor Kohncke
  • Patent number: 7041708
    Abstract: Ultraviolet (UV)-curable polyurethane compositions are provided which are made by reacting an isocyanate with an ultraviolet (UV)-curable polyol that is made by co-polymerizing an alkylene oxide, an unsaturated carboxylic acid or anhydride and a hydroxy functional compound and which has an ultra-low level of unsaturation. The inventive ultraviolet (UV)-curable polyurethane compositions may find use in or as coatings, adhesives, sealants, elastomers and the like.
    Type: Grant
    Filed: October 29, 2004
    Date of Patent: May 9, 2006
    Assignee: Bayer MaterialScience LLC
    Inventors: Bi Le-Khac, Karl W. Haider, Ramesh Subramanian, Charles A. Gambino, James Edward Kassner
  • Publication number: 20060094714
    Abstract: The invention relates generally to compounds described herein. More specifically, the invention relates to compounds and pharmaceutical compositions containing such compounds. Methods of the invention comprise administration of a compound of the invention for the treatment of diabetes and related disorders.
    Type: Application
    Filed: March 26, 2004
    Publication date: May 4, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: William Bullock, Qingjie Liu
  • Publication number: 20060094769
    Abstract: The invention relates to compounds of formulae (II), (IV), and (VI) as shown below, wherein the several variable groups are as defined in the specification and claims. Processes for making these materials, and methods for using them in the synthesis of compounds for treatment of cardiovascular disorders and fibrotic disorders are also disclosed.
    Type: Application
    Filed: August 8, 2005
    Publication date: May 4, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Cristina Alonso-Alija, Markus Heil, Dietmar Flubacher, Paul Naab, Josef Pernerstorfer, Johannes-Peter Stasch, Frank Wunder, Klaus Dembowsky, Elizabeth Perzborn, Elke Stahl
  • Patent number: 7037982
    Abstract: This invention relates to a rubber mixture containing a carboxylated nitrile rubber, a metal salt of an acrylate, a liquid acrylate, a silane, optionally together with further additives, to a process for the production thereof and to use for moldings of all kinds, in particular roll coverings.
    Type: Grant
    Filed: January 15, 2002
    Date of Patent: May 2, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventor: Erich Fuchs