Patents Assigned to Bayer
  • Fluorescent creatinine assay
    Patent number: 6872573
    Abstract: A method of detecting creatinine in body fluids using an indicator which produces a fluorescent response when oxidized in the presence of a copperII/creatinine complex. A preferred indicator is 4-(1-methylhydrazino)-7-nitro benzooxadiazole (MNBDH).
    Type: Grant
    Filed: January 2, 2003
    Date of Patent: March 29, 2005
    Assignee: Bayer Corporation
    Inventors: James P. Albarella, Robert P. Hatch
  • Method and apparatus for controlling a stream of liquid test packages in a capsule chemistry analysis system
    Patent number: 6872571
    Abstract: A method and apparatus for controlling a stream of liquid and air segments wherein the liquid and air segments are selectively aspirated into a first fluid conduit in a plurality of cycles, each cycle beginning with the aspiration of a first air segment and ending with the aspiration of a final air segment. The liquid and air segments are then transferred from the first fluid conduit to a second fluid conduit. The volume of the final air segment of each cycle is then adjusted after the final air segment has moved into the second fluid conduit. Next, the liquid segments and the air segments of each cycle are transferred from the second fluid conduit to a third fluid conduit. The volume of the first air segment of each cycle is then adjusted after the first air segment has moved into the third fluid conduit.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: March 29, 2005
    Assignee: Bayer Corporation
    Inventors: Robert Adolfsen, Paul Gherson, David Lightbody
  • Stents
    Publication number: 20050064006
    Abstract: The invention concerns stents containing compounds of formula (I) and methods for making said stents as well as their use.
    Type: Application
    Filed: October 11, 2002
    Publication date: March 24, 2005
    Applicant: Bayer Aktiengesellschaft
    Inventors: Elisabeth Perzborn, Jochen Kalbe, Wolfram Ledwoch, Didier Meulien
  • Substituted dihydroquinazolines
    Publication number: 20050065160
    Abstract: The invention relates to substituted dihydroquinazolines and to processes for their preparation and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as antiviral agents, in particular against cytomegalo viruses.
    Type: Application
    Filed: April 26, 2004
    Publication date: March 24, 2005
    Applicant: Bayer HealthCare AG
    Inventors: Tobias Wunberg, Judith Baumeister, Ulrich Betz, Mario Jeske, Thomas Lampe, Susanne Nikolic, Jurgen Reefschlager, Rudolf Schohe-Loop, Frank Sussmeier, Holger Zimmermann, Rolf Grosser, Kerstin Henninger, Guy Hewlett, Jorg Keldenich, Dieter Lang, Peter Nell
  • Novel heterocycles 3
    Publication number: 20050065153
    Abstract: The invention relates to 7-(4-tert butyl-cyclohexyl)-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Application
    Filed: October 12, 2004
    Publication date: March 24, 2005
    Applicant: Bayer Aktiengesellschaft
    Inventors: Cristina Alonso-Alija, Heike Gielen, Martin Hendrix, Ulrich Niewohner, Dagmar Schauss, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary Fitzgerald, Graham Sturton, Maria Niewohner
  • Surfactant/solvent mixtures
    Publication number: 20050064004
    Abstract: The present invention relates to surfactant/solvent mixtures comprising a) one or more solvents of the formula (I): R—CO—N—R1R2??(I) in which R=H methyl, ethyl or propyl, where ?) if R=H or methyl, R1 and R2 are identical or different and are tert-butyl, (C5-C12)alkyl or (C1-C12)hydroxyalkyl, and ?) if R=ethyl or propyl, R1 and R2 are identical or different and are (C1-C12)alkyl or (C1-C12)hydroxyalkyl, and b) one or more surfactants. The surfactant/solvent mixture according to the invention is suitable for the preparation of active ingredient formulations.
    Type: Application
    Filed: September 17, 2004
    Publication date: March 24, 2005
    Applicant: Bayer CropScience GmbH
    Inventors: Gerhard Schnabel, Gerhard Frisch, Andreas Rochling
  • Methods for screening and identifying compounds
    Publication number: 20050064531
    Abstract: The present invention relates to methods for assessing enzyme activity utilizing a phase partition system. In addition, the present invention also relates to methods for screening and identifying compounds that may be used, for example, for the treatment of diabetes, diabetes-related disorders, obesity, cardiovascular disease, cancer, and other diseases or disorders, using this phase partition system.
    Type: Application
    Filed: August 4, 2004
    Publication date: March 24, 2005
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: James Landro, David Osterman, Walter Pickett
  • Electrophosphorescent arrangement comprising conductive polymers
    Patent number: 6869697
    Abstract: The invention relates to layer arrangement having (i) at least one transparent substrate containing an electrically conductive layer, (ii) an electro-optically active layer, and (iii) a further substrate containing an electrically conductive layer, wherein at least one of the two electrically conductive substrates is additionally coated with an organic conductive polymer system and the electro-optically active layer contains an electrophosphorescent compound.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: March 22, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Helmut-Werner Heuer, Rolf Wehrmann
  • Amine-initiated polyether polyols and a process for their production
    Patent number: 6869543
    Abstract: Clear, amine-initiated polyether polyols are made by epoxidizing an amine in the presence of an alkali metal hydroxide catalyst. By reducing the amount of catalyst used during the polyol synthesis and by adding the catalyst after between 5 and 30% of the total amount of at least one alkylene oxide has been added, after lactic acid neutralization, gives a short chain polyol that has foam processing characteristics similar to the conventional sulfuric acid neutralized polyol. The polyols produced in this manner are particularly useful for the production of polyurethane and polyisocyanurate foams.
    Type: Grant
    Filed: February 21, 2003
    Date of Patent: March 22, 2005
    Assignee: Bayer Polymers LLC
    Inventors: Nathan L. Anderson, Karl W. Haider, Keith J. Headley, Kerry A. Ingold, Herman P. Doerge
  • Process for the preparation of thermoplastic, non-tacky polyurethanes
    Patent number: 6869999
    Abstract: Thermoplastic polyurethanes (TPU) with a low tendency towards surface tackiness of the granules are prepared by applying at least one wetting agent satisfying specified criteria and at least one solid powdering agent to the TPU before and/or after comminution of the TPU.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: March 22, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kaufhold, Eva Gestermann, Wolfgang Röhrig
  • Immunogenic peptides of foot-and-mouth disease viruses
    Publication number: 20050058656
    Abstract: The present invention relates to FMDC vaccine based on peptides having a sequence of at least 8 amino acids, which corresponds to a partial sequence of the non-structural protein region of FMDV, which was selected by immunoreactivity with FMDV-specific antibodies or by immunoreactivity with FMDV-specific T lymphocytes, and to their production and their use.
    Type: Application
    Filed: November 9, 2004
    Publication date: March 17, 2005
    Applicant: Bayer Aktiengesellschaft
    Inventors: Roberto Correa, Hans-Robert Hehnen, Eberhard Pfaff, Armin Saalmuller, Thomas Pauly, Bettina Hohlich, Bernadette Glatthaar-Saalmuller, Karl-Heinz Wiesmuller
  • Method for the electolysis of an aqueous solution of hydrogen chloride or alkali metal chloride
    Publication number: 20050056549
    Abstract: A method is described for the electrolysis of an aqueous solution of hydrogen chloride or alkali metal chloride in an electrolysis cell. The cell includes at least of an anode half-element and an anode, a cathode half-element and a gas diffusion electrode as the cathode, and a cation exchange membrane for separating the anode half-element and the cathode half-element. A gas containing oxygen is supplied to the cathode half-element and excess gas containing oxygen is discharged from the cathode half-element. Excess gas containing oxygen discharged from the cathode half-element is subjected to catalytic oxidation of hydrogen.
    Type: Application
    Filed: September 10, 2004
    Publication date: March 17, 2005
    Applicant: Bayer MaterialScience AG
    Inventors: Fritz Gestermann, Richard Malchow, Walter Hansen, Gaby Sengstock
  • Modified IL-4 mutein receptor antagonists
    Publication number: 20050059590
    Abstract: This invention relates to modified IL-4 mutein receptor antagonists comprising an IL-4 mutein receptor antagonist coupled to polyethylene glycol. Related formulations and dosages and methods of administration thereof for therapeutic purposes are also provided. These modified IL-4 mutein receptor antagonists, compositions and methods provide a treatment option for those individuals afflicted with a respiratory disorder such as asthma by inhibiting IL-4 and IL-13-mediated airway hyperresponsiveness and eosinophilia. More particularly, these antagonists have an increased duration of effect versus unmodified IL-4RA by virtue of a greater plasma half-life.
    Type: Application
    Filed: April 8, 2004
    Publication date: March 17, 2005
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Clark Pan, Steve Roczniak, Jeffrey Greve, Stephanie Yung, Malinda Longphre, Teresa Wong, Adrian Tomkinson
  • In-line process for monitoring binder dosage and distribution on a surface and apparatus useful therefor
    Patent number: 6867421
    Abstract: A method and apparatus for determining binder dosage and distribution on a substrate. The apparatus employed is made up of: a) a source of long wave ultraviolet light positioned so that ultraviolet waves emitted therefrom will come into contact with a substrate to which binder has been applied, b) a filter which blocks ultraviolet waves emitted from the UV source and reflected by the substrate but which allows visible light waves emitted by fluorescence of the binder to pass, c) a lens for imaging visible light onto a focal plane, d) a video camera positioned at the focal plane of the lens which converts the visible light waves that have passed through the filter and the lens into an electrical signal, and e) a device capable of correlating images received by the video camera to binder dosage and distribution on the substrate contacted by the ultraviolet waves emitted by the UV source.
    Type: Grant
    Filed: December 29, 1998
    Date of Patent: March 15, 2005
    Assignee: Bayer Materialscience LLC
    Inventors: Robert N. Hunt, Terry L. Thiem
  • 6-carboxyphenyldihydropyridazinone derivatives and use thereof
    Patent number: 6867206
    Abstract: The present invention relates to 6-carboxyphenyldihydropyridazinone derivatives having the formula wherein R1, R2, R3, A, D, G, and E are as defined in the specification and claims, a process for preparing these materials, pharmaceutical compositions containing them, and a method for using them in the treatment of anemias.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: March 15, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Gabriele Bräunlich, Michael Lögers, Carsten Schmeck, Ulrich Nielsch, Martin Bechem, Christoph Gerdes, Michael Sperzel, Klemens Lustig, Werner Stürmer
  • Double-metal cyanide catalysts which can be used to prepare polyols and the processes related thereto
    Patent number: 6867162
    Abstract: The present invention is directed to double metal cyanide catalysts (“DMC”) which are prepared by combining i) at least one metal salt; ii) at least one metal cyanide salt; iii) at least one organic complexing ligand; iv) at least one alkali metal salt; and, optionally, v) at least one functionalized polymer under conditions sufficient to form a catalyst; and adding a sufficient amount of the at least one alkali metal salt to the catalyst so formed in an amount such that the catalyst includes the at least one alkali metal salt in an amount of from about 0.4 to about 6 wt. % based on the total weight of the catalyst. The polyols produced in the presence of the catalysts of the present invention have reduced levels of high molecular weight tail.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: March 15, 2005
    Assignees: Bayer MaterialScience LLC, Bayer Antwerpen, J.V.
    Inventors: Bi Le-Khac, Wie Wang
  • Fluidics circuit of hematology analyzer with heated reaction chamber
    Publication number: 20050054114
    Abstract: The fluid circuit for a hematology analyzer includes a block-like plastic member with passageways for fluid, and a reaction chamber recess that communicates with one or more of the fluid passageways. A detachable metallic heat transfer cover member is positioned across the reaction chamber recess to close the reaction chamber recess and establish a confined reaction chamber. A heater is placed in conductive contact with the metallic heat transfer cover member to heat the cover member and thereby conduct heat to the reaction chamber. The metallic heat transfer cover member is detachably secured to the block-like plastic member and can thus be removed and replaced as needed.
    Type: Application
    Filed: September 9, 2003
    Publication date: March 10, 2005
    Applicant: BAYER CORPORATION
    Inventors: Joseph Raneri, Joseph Carlucci, Bruce Behringer, Michael Peets, Terry Goodsell
  • Polyorganosiloxane compositions which can be painted or coated over
    Publication number: 20050054765
    Abstract: The invention relates to a polyorganosiloxane composition, which is obtained by means of a method comprising the mixing and reacting of given components, a vulcanized elastic polyorganosiloxane composition, which is obtained by reacting the polyorganosiloxane compositions through contact with water or water vapor and the use of the vulcanized polyorganosiloxane compositions as joint sealings, adhesives, profiles, coatings or formed-in-place gaskets.
    Type: Application
    Filed: November 20, 2002
    Publication date: March 10, 2005
    Applicant: GE Bayer Silicones GmbH & Co KG
    Inventor: Markus Putzer
  • Substituted aryl ketones
    Patent number: 6864219
    Abstract: The invention relates to novel substituted aryl ketones of the general formula (I) wherein all variables are as defined in the specification, and to processes for their preparation, to intermediates and to the use of these compounds as herbicides.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: March 8, 2005
    Assignees: Bayer Aktiengesellschaft, Nihon Bayer Agrochem, K.K.
    Inventors: Otto Schallner, Stefan Lehr, Hans-Georg Schwarz, Klaus-Helmut Müller, Dorothee Hoischen, Mark Wilhelm Drewes, Peter Dahmen, Dieter Feucht, Rolf Pontzen, Akihiko Yanagi, Shinichi Narabu, Toshio Goto
  • Active substance combinations having insecticidal and acaricidal properties
    Patent number: 6864276
    Abstract: The invention relates to insecticidal mixtures for protecting plants against attack by pests comprising (a) compounds of the formula (I) ?in which W, X, Y, Z, A, B, D and G are each as defined in the disclosure, and (b) agonists or antagonists of nicotinic acetylcholine receptors.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: March 8, 2005
    Assignee: Bayer Cropscience AG
    Inventors: Reiner Fischer, Christoph Erdelen