Abstract: The invention relates generally to naphthyridine derivatives of the formula wherein one of U, X, Y and Z is nitrogen and the others are C—R, where R is hydrogen or a substituent. More specifically, the invention relates to 1,8-naphthyridine derivatives and pharmaceutical compositions containing such derivatives. Methods of the invention comprise administration of a naphthyridine derivative of the invention for the treatment of diabetes and related disorders.
Type:
Grant
Filed:
September 23, 2002
Date of Patent:
May 31, 2005
Assignee:
Bayer Pharmaceuticals Corporation
Inventors:
Yamin Wang, William H. Bullock, David E. Gunn, Qingjie Liu, Sidney X. Liang, Donglei Liu, Steven R. Magnuson, Tindy Li, Eric S. Mull, Jill E. Wood, Ning Qi
Abstract: The invention relates to a method for detecting one or more analytes by a recognition reaction, using a device with an electrolyte-filled electrolyte space, having at least one measurement electrode, optionally with an insulating region (insulator layer) next to the measurement electrode, and recognition molecules which are immobilized on the measurement electrode and/or on the insulating region next to the measurement electrode, and a counterelectrode. The electrical conductance or the resistance between the measurement electrode/s and the counterelectrode is measured as a function of the development time, and the time profile of the conductance or the resistance is analyzed. The invention also relates to a device with which the method according to the invention can be carried out.
Abstract: The invention relates to a process for manufacturing chlorosilanes, in which methyl-rich disilane, polysilane and siloxane residues from the Müller-Rochow synthesis or a chlorosilane synthesis are reduced in quantity. It comprises the steps: a) reaction of silicon with alkyl halogenides, aryl halogenides or hydrogen chloride, b) reaction of at least one high-boiling product fraction from step a) with at least one halogenide and c) reaction of at least one high-boiling product fraction resulting from step b) with alkyl halogenides, aryl halogenides and/or chlorosilanes.
Type:
Application
Filed:
August 4, 2004
Publication date:
May 26, 2005
Applicant:
GE Bayer Silicones GmbH & Co.
Inventors:
Roland Wagner, Ralf Maecker, Hubertus Eversheim, Horst Lange
Abstract: A herbicidally active composition, comprising (A) one or more sulfonylureas from the group consisting of metsulfuron, thifensulfuron, tribenuron, chlorsulfuron and their salts and esters, and (B) one or more safeners from the group consisting of mefenpyr, isoxadifen, cloquintocet, fenchlorazole and their salts and esters.
Type:
Application
Filed:
October 28, 2004
Publication date:
May 26, 2005
Applicant:
Bayer CropScience GmbH
Inventors:
Frank Ziemer, Gerhard Schnabel, Detlev Haase, Roland Deckwer, Chrisopher Rosinger, David Feist
Abstract: The tetrahydroquinolines can be prepared by condensing appropriately substituted tetrahydroquinoline aldehydes with suitable substances and subsequently varying the substituents present by customary methods. The tetrahydroquinolines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of arteriosclerosis and dyslipidaemias.
Type:
Grant
Filed:
March 31, 2003
Date of Patent:
May 24, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Gunter Schmidt, Jürgen Stoltefuss, Michael Lögers, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt
Abstract: The invention relates to novel mixtures of sulfuric esters and specific sulfuric esters that are useful as leveling agents for the dyeing of nitrogenous fiber materials and to a process for their preparation by reacting sulfuryl chloride with specific alcohols.
Abstract: The present invention relates to a novel process for preparing 8-methoxy-3-quinolonecarboxylic acids which are antibiotics having potent antibacterial action.
Type:
Grant
Filed:
April 3, 2003
Date of Patent:
May 24, 2005
Assignee:
Bayer HealthCare Aktiengesellschaft
Inventors:
Reinhold Gehring, Klaus Mohrs, Werner Heilmann, Herbert Diehl
Abstract: The invention relates to an optical data carrier having a preferably transparent substrate that has optionally previously been coated with one or more reflection layers and to the surface of which has been applied a light-writeable information layer, optionally one or more reflection layers, and optionally a protective layer or a further substrate or a covering layer, such that the optical data carrier can be written on or read by means of blue light (preferably laser light having a specified wavelength) or by means of infrared light (preferably laser light having a specified wavelength), wherein the information layer contains (i) light-absorbent phthalocyanine dyes of the formula (I) where Me is a doubly axially substituted Si, Ge, and Sn atom, Pc is an unsubstituted phthalocyanine, and X1 and X2 are each independently halogen, and (ii) optionally, a binder.
Type:
Grant
Filed:
August 16, 2002
Date of Patent:
May 24, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Horst Berneth, Friedrich-Karl Bruder, Wilfried Haese, Rainer Hagen, Karin Hassenrück, Serguei Kostromine, Peter Landenberger, Rafael Oser, Thomas Sommermann, Josef-Walter Stawitz
Abstract: The invention relates to nucleic acid molecules which code for enzymes and which are involved in the synthesis of starch in plants. These enzymes concern isoamylases derived from wheat. The invention also relates to vectors and host cells which contain the described nucleic acid molecules, especially transformed plant cells and plants which can be regenerated therefrom, which exhibit an increased or reduced activity of the inventive isoamylases.
Abstract: Use of agonists and antagonists of the nicotinergic acetylcholine receptors of insects for the non-systemic control of parasitic insects, such as fleas, lice and flies, on humans and on animals.
Abstract: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases and to pharmaceutical compositions containing these compounds.
Abstract: A method for determining the concentration of catalyst material in suspension in a hydrogenation reaction mixture on-line by determining the potential difference between a measuring electrode which dips into the reaction mixture and a reference electrode.
Abstract: The invention relates to insecticidal and acaricidal mixtures comprising certain cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors for protecting plants against attack by pests.
Abstract: The invention provides fungicidal compounds of formula (I) and salts thereof wherein: R1 is alkyl, alkenyl, alkynyl, carbocyclyl or heterocyclyl, each of which may be substituted, or hydrogen; R2 and R3, which may be the same or different, are any group defined for R1; cyano; acyl; —ORa or —SRa, where Ra is alkyl, alkenyl, alkynyl, carbocyclyl or heterocyclyl, each of which may be substituted; or R2 and R3, or R2 and R1, together with their interconnecting atoms may form a ring, which may be substituted; R4 is alkyl, alkenyl, alkynyl, carbocyclyl or heterocyclyl, each of which may be substituted; hydroxy; mercapto; azido; nitro; halogen; cyano; acyl; optionally substituted amino; cyanato; thiocyanato; —SF5; —ORa; —SRa or —Si(Ra)3; m is 0 to 3; when present R5, which may be the same or different to any other R5, is any group defined for R4; R6 is optionally substituted carbo- or heterocylclyl; and A is a defined linking group, or —A—R6 and R5 together with benzene ring M form an optionally substituted fused ri
Type:
Grant
Filed:
February 4, 2000
Date of Patent:
May 17, 2005
Assignee:
Bayer Cropscience GmbH
Inventors:
Mark David Charles, Wilfried Franke, David Eric Green, Thomas Lawley Hough, Dale Robert Mitchell, Donald James Simpson, John Frederick Atherall
Abstract: The present invention relates to aliphatic oligocarbonate polyols prepared by the transesterification of organic carbonates with aliphatic polyols in the presence of at least one catalyst which contains i) at least one rare earth metal or compounds thereof or ii) at least one metal of group III B of the periodic table of the elements or compounds thereof or iii) mixtures of i) and ii) and to a process for preparing the same.
Type:
Grant
Filed:
November 18, 2002
Date of Patent:
May 17, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Steffen Hofacker, Christoph Gürtler, Jörg Tillack
Abstract: A process of preparing a branched (co)polycarbonate resin is disclosed. The process entails using at least one compound conforming to formulae 1a or 1b in which R1, R2 and R3 independently denote linear or branched C1-C10-alkyl, R4 and R5 independently denote hydrogen or linear or branched C1-C10-alkyl, p1 and p2 independently of one another denote a whole number between 3 and 10, as a branching agent.
Type:
Grant
Filed:
April 1, 2004
Date of Patent:
May 17, 2005
Assignee:
Bayer Materialscience AG
Inventors:
Helmut-Werner Heuer, Rolf Wehrmann, Michael Erkelenz
Abstract: A transparent heat-absorbent multi-layer structure comprising, (A) a first layer, and (B) a second layer is described. The first layer (A) contains at least one organic infrared absorber (e.g., a phthalocyanine) and at least one ultraviolet absorber (e.g., a benzotriazole), and the second layer (B) contains at least one ultraviolet absorber and is substantially free of organic infrared absorbers. The first layer (A) is the only layer in the multi-layer structure that contains an organic infrared absorber. Also described is a method of preparing the multi-layer structure. Molded articles that may comprise the multi-layer structure of the present invention include glazings, such as automotive glazings.
Type:
Grant
Filed:
April 4, 2002
Date of Patent:
May 17, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Martin Döbler, Peter Bier, Rüdiger Gorny, Monika Stihler
Abstract: A description is given of derivatives of benzoylpyrazoles of the formula (I) and of their use as herbicides. In this formula (I) R1a, R1b, R1c, R2, R3, R4 and R5 stand for various radicals, X for a bridging atom, L for a carbon chain and Y for a chalcogen atom.
Type:
Grant
Filed:
August 5, 2003
Date of Patent:
May 17, 2005
Assignee:
Bayer CropScience GmbH
Inventors:
Thomas Seitz, Andreas van Almsick, Lothar Willms, Thomas Auler, Hermann Bieringer, Hubert Menne
Abstract: The present invention is directed to a blocked polyisocyanate based on nonane triisocyanate. More particularly, the invention is directed to a blocked polyisocyanate useful in solvent borne coating compositions and comprising the reaction product of: a) nonane triisocyanate; b) a pyrazole blocking agent; and c) a diol or polyol.
Type:
Grant
Filed:
November 26, 2003
Date of Patent:
May 17, 2005
Assignee:
Bayer MaterialScience LLC
Inventors:
Richard R. Roesler, Patricia B. Jacobs, Dinesh Pethiyagoda, Tabitha H. Riggio, Marianne M. Salek, Emery Yuhas
Abstract: The invention relates to a process for the continuous preparation of oleum of a concentration of 10 to 45% by weight of SO3 and/or sulphuric acid of a concentration of 94 to 100% by weight of H2SO4 by combustion of sulphur with atmospheric oxygen according to the principle of superstoichiometric combustion, cooling the resultant sulphur-dioxide-containing gases to 350° C. to 500° C., catalytic conversion of these cooled gases to give sulphur-trioxide-containing gases in the presence of a vanadium-containing catalyst using single or double contact catalysis, absorption of the sulphur-trioxide-containing gases after cooling, if appropriate removal of liquids from the gases after absorption and energy recovery, with liquid sulphur being injected into the hot combustion gas stream perpendicular to the main direction of flow in the form of a fan using one or more bimodal fan-type nozzles.
Type:
Grant
Filed:
August 29, 2002
Date of Patent:
May 17, 2005
Assignee:
Bayer Aktiengesellschaft
Inventors:
Kurt-Wilhelm Eichenhofer, Klaus-Peter Grabowski, Günter Dräger, Martin Kürten, Martin Schweitzer