Patents Assigned to Baylor
  • SYSTEM AND METHOD FOR A MULTI-PRIMARY WIDE GAMUT COLOR SYSTEM
    Publication number: 20220223089
    Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Application
    Filed: March 25, 2022
    Publication date: July 14, 2022
    Applicant: Baylor University
    Inventors: Mitchell J. Bogdanowicz, Gary B. Mandle
  • SYSTEM AND METHOD FOR A MULTI-PRIMARY WIDE GAMUT COLOR SYSTEM
    Publication number: 20220215787
    Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Application
    Filed: March 24, 2022
    Publication date: July 7, 2022
    Applicant: Baylor University
    Inventors: Gary B. Mandle, James M. DeFilippis
  • SYSTEM AND METHOD FOR A SIX-PRIMARY WIDE GAMUT COLOR SYSTEM
    Publication number: 20220215788
    Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. A six-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Application
    Filed: March 25, 2022
    Publication date: July 7, 2022
    Applicant: Baylor University
    Inventor: Gary B. Mandle
  • Platform for enhanced targeted delivery
    Patent number: 11376332
    Abstract: Embodiments of the disclosure concern methods and compositions for delivering therapeutic, diagnostic or interventional moieties, such as complex and simple entities such as biologies, including at least cells, for example. The methods employ targeted delivery by employing at least one ALCAM-binding moiety on the therapeutic, diagnostic or interventional moiety to be delivered. In specific cases, the ALCAM-binding moiety is present on or with the therapeutic moiety in multiple iterations. In certain embodiments, the ALCAM-binding moiety comprises at least one SRCR domain from CD6 and a stalk, such as from CD6, of the secretable or molecular form thereof.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: July 5, 2022
    Assignee: Baylor College of Medicine
    Inventors: Nabil M. Ahmed, Hebatalla S. Samaha, Antonella Pignata, Kristen Fousek
  • System and method for a multi-primary wide gamut color system
    Patent number: 11373575
    Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: June 28, 2022
    Assignee: BAYLOR UNIVERSITY
    Inventors: Mitchell J. Bogdanowicz, Corey P. Carbonara, Michael F. Korpi, James M. DeFilippis, Gary B. Mandle
  • USES OF A2 DOMAIN OF VON WILLEBRAND FACTOR
    Publication number: 20220193204
    Abstract: Embodiments of the disclosure encompass methods and compositions for maintaining a healthy fibrin network in an individual. The disclosure includes methods of targeting fibrin in an individual for the purpose of restoring fibrin that is subject to a level of fibrinolysis that is deleterious, such as excessive or reduced with respect to the general population. Such modifications of fibrin in an individual may include direct targeting of fibrin with the A2 domain of von Willebrand factor or a functional derivative or fragment thereof. In specific embodiments, the methods restore to a normal level any imbalance between coagulation and inflammation.
    Type: Application
    Filed: May 14, 2020
    Publication date: June 23, 2022
    Applicant: BAYLOR COLLEGE OF MEDICINE
    Inventors: Miguel Angel CRUZ, Trung NGUYEN
  • Methods for Treating Osteogenesis Imperfecta
    Publication number: 20220195025
    Abstract: The present invention provides methods for treating and improving the symptoms of osteogenesis imperfecta (OI) in a subject by administering to the subject a therapeutically effective amount of a binding agent that binds to transforming growth factor beta (TGF?).
    Type: Application
    Filed: December 9, 2021
    Publication date: June 23, 2022
    Applicants: GENZYME CORPORATION, Baylor College of Medicine
    Inventors: Brendan Lee, Kuber T. Sampath
  • TROCARS
    Publication number: 20220192480
    Abstract: One aspect of the invention provides a trocar including: a central cylinder defining a central channel and having a distal end adapted and configured for insertion within a subject; one or more gas outlets located within the central cylinder proximate to the distal end of the trocar; and one or more liquid outlets located within the central cylinder on a proximal side of the one or more gas outlets. The one or more liquid outlets are adapted and configured to dispense a liquid when an endoscope is withdrawn from a fully extended position within the central channel of the trocar to a position proximate to the one or more liquid outlets. Distal advancement of the endoscope to a position adjacent to the one or more gas outlets removes liquid from a distal end of the endoscope.
    Type: Application
    Filed: March 11, 2022
    Publication date: June 23, 2022
    Applicants: Baylor College of Medicine, Texas Heart Institute
    Inventors: Bryan M. BURT, Mahmood KHAN, William COHN
  • UNIVERSALLY FRIENDLY OBTURATOR (UFO) FOR BRACHYTHERAPY TREATMENT OF CERVICAL CANCER
    Publication number: 20220184417
    Abstract: The present invention provides a brachytherapy applicator device having: an elongate body defining a plurality of brachytherapy needle channels, each adapted and configured to receive a brachytherapy needle; a proximal end defining a plurality of proximal openings, each in communication with one of the plurality of brachytherapy needle channels; and a distal end defining a plurality of distal openings, each in communication with one of the plurality of brachytherapy needle channels, wherein at least some of the plurality of brachytherapy needle channels are curved away from a central axis of the elongate body at the distal end such that a brachytherapy needle inserted therethrough will engage with tissue lateral to a cross-sectional profile of the distal end of the elongate body.
    Type: Application
    Filed: December 14, 2021
    Publication date: June 16, 2022
    Applicants: Baylor College of Medicine, William Marsh Rice University
    Inventors: Alexander Hanania, Michelle S. Ludwig, Elisa Arango, Susannah Dittmar, Krithika Kumar, Lauren Payne, Sanika Rane, Andrea Samantha Gobin
  • Combination therapies for treating infantile spasms and other treatment resistant epilepsies
    Patent number: 11351229
    Abstract: The present invention provides methods of treating infantile spasms in a subject in need thereof. In certain embodiments, the method comprises administering to the subject both vigabatrin (VGB) and insulin-like growth factor 1 (IGF-1), a biologically active fragment thereof, or any derivative thereof.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: June 7, 2022
    Assignee: Baylor College of Medicine
    Inventors: John W. Swann, Chong L. Lee, John T. Le, James D. Frost, Jr.
  • SYSTEM AND METHOD FOR A MULTI-PRIMARY WIDE GAMUT COLOR SYSTEM
    Publication number: 20220172663
    Abstract: The present invention includes systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Application
    Filed: February 11, 2022
    Publication date: June 2, 2022
    Applicant: Baylor University
    Inventors: Mitchell J. Bogdanowicz, Corey P. Carbonara, Michael F. Korpi, James M. DeFilippis, Gary B. Mandle
  • Structure of GII.4 norovirus protease—design of broad-spectrum protease inhibitors
    Patent number: 11344600
    Abstract: The present disclosure concerns inhibitors of Norovirus protease that are suitable for use against any genotype of Norovirus, including at least GII.4 Norovirus proteases. In particular embodiments, specific compositions are encompassed, including their use for prevention or treatment of Norovirus infection in an individual.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: May 31, 2022
    Assignee: Baylor College of Medicine
    Inventors: B. Venkataram Prasad, Mary K. Estes, Yongcheng Song
  • METHOD AND SYSTEM FOR DETECTION AND ANALYSIS OF THORACIC OUTLET SYNDROME (TOS)
    Publication number: 20220160259
    Abstract: Motion data collected by a sensing device attached to a patient's arm may be used to determine whether the arm is subject to thoracic outlet syndrome (TOS) Motion data regarding motion of an arm of a patient may be received from a sensing device. One or more extremity performance parameters for the arm may be determined based, at least in part, on the motion data. A determination may be made based, at least in part, on the one or more extremity performance parameters whether the arm is subject to TOS.
    Type: Application
    Filed: April 2, 2020
    Publication date: May 26, 2022
    Applicant: Baylor College of Medicine
    Inventors: Bryan Burt, Bijan Najafi, Mohsen Zahiri, Changhong Wang
  • SYSTEM AND METHOD FOR A MULTI-PRIMARY WIDE GAMUT COLOR SYSTEM
    Publication number: 20220165198
    Abstract: The present invention includes systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Application
    Filed: February 11, 2022
    Publication date: May 26, 2022
    Applicant: Baylor University
    Inventors: Mitchell J. Bogdanowicz, Ph.D., Corey P. Carbonara, Ph.D., Michael F. Korpi, James M. DeFilippis, Gary B. Mandle
  • SYSTEM AND METHOD FOR A MULTI-PRIMARY WIDE GAMUT COLOR SYSTEM
    Publication number: 20220165199
    Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Application
    Filed: February 14, 2022
    Publication date: May 26, 2022
    Applicant: Baylor University
    Inventors: Gary B. Mandle, James M. DeFilippis, Mitchell J. Bogdanowicz, Ph.D., Corey P. Carbonara, Ph.D., Michael F. Korpi
  • System and method for a multi-primary wide gamut color system
    Patent number: 11341890
    Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: May 24, 2022
    Assignee: BAYLOR UNIVERSITY
    Inventors: Mitchell J. Bogdanowicz, Corey P. Carbonara, Michael F. Korpi, James M. DeFilippis, Gary B. Mandle
  • AGENTS THAT ENGAGE ANTIGEN-PRESENTING CELLS THROUGH DENDRITIC CELL ASIALOGLYCOPROTEIN RECEPTOR (DC-ASGPR)
    Publication number: 20220152192
    Abstract: The present invention includes compositions and methods for making and using anti DC-ASGPR antibodies that can, e.g., activate DCs and other cells.
    Type: Application
    Filed: November 9, 2021
    Publication date: May 19, 2022
    Applicant: BAYLOR RESEARCH INSTITUTE
    Inventors: SangKon OH, Dapeng LI
  • SERIALLY EXPANDING AN ARTIFICIAL HEART VALVE WITHIN A PEDIATRIC PATIENT
    Publication number: 20220125581
    Abstract: Some embodiments are directed to methods for serially expanding an artificial heart valve within a pediatric patient. For example, the artificial heart valve can be implanted into the pediatric patient during a first procedure, and then expanded during a second procedure to accommodate for the pediatric patient's growth. Some embodiments include introducing an expander into the implanted valve when the frame is expanded to a first working diameter, and then actuating the expander to expand the frame to a second working diameter greater than the first working diameter, to accommodate for the pediatric patient's growth.
    Type: Application
    Filed: September 17, 2021
    Publication date: April 28, 2022
    Applicants: Baylor College of Medicine, William Marsh Rice University
    Inventors: Henri JUSTINO, Daniel HARRINGTON, Kwonsoo CHUN
  • DEVICES AND METHODS FOR MEASURING BRAIN STATE
    Publication number: 20220125369
    Abstract: One aspect of the invention provides a method of measuring brain state. The method includes: receiving a first plurality of electrical signals from a contact lens placed on a surface of a subject's eye, the first plurality of electrical signals associated with a first plurality of electrodes lying adjacent to an iris dilator muscle of the subject's eye. Another aspect of the invention provides a contact lens including: an optically transparent or translucent substrate; and one or more pairs of electromyography electrodes arranged on or within the optically transparent or translucent substrate. At least one of the one or more pairs electromyography electrodes are arranged to lie adjacent to an iris dilator muscle of a subject's eye when the contact lens is placed on the eye.
    Type: Application
    Filed: February 26, 2020
    Publication date: April 28, 2022
    Applicants: Baylor College of Medicine, Wisconsin Alumni Research Foundation
    Inventors: Matthew McGinley, Justin Williams, Aaron Suminski
  • Small molecule stimulators of steroid receptor coactivator proteins and their use in the treatment of cancer
    Patent number: 11312676
    Abstract: Small molecule stimulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing cancer. Also provided are methods for stimulating SRC family proteins in a cell.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: April 26, 2022
    Assignee: BAYLOR COLLEGE OF MEDICINE
    Inventors: David Michael Lonard, Lei Wang, Bert W. O'Malley, Jianming Xu, Yongcheng Song, Xiaonan Li, Timothy Gerald Palzkill