Patents Assigned to Baylor
  • SYSTEM AND METHOD FOR DISPLAYING SUPER SATURATED COLOR
    Publication number: 20220392030
    Abstract: Systems and methods for displaying super saturated color. Image data for display on a display or viewing device with a potential white luminance in a standard system with a maximum luminance is processed such that colors near the white point are reduced to a limited luminance. As the chroma of the displayed color is increased, a luminance attenuation is decreased. The scaling of the reduction is operable to be a linear function, a non-linear function, or any other function.
    Type: Application
    Filed: May 19, 2022
    Publication date: December 8, 2022
    Applicant: Baylor University
    Inventors: Mitchell J. Bogdanowicz, Ph.D., James M. DeFilippis, Gary B. Mandle, Corey P. Carbonara, Ph.D., Michael F. Korpi
  • Combination therapy to treat urea cycle disorders
    Patent number: 11517547
    Abstract: Embodiments of the disclosure include certain formulations for methods of treating urea cycle disorders. The methods encompass compositions that comprise benzoate and phenylbutyrate that may be at certain doses and have certain ratios of the components. The benzoate and phenylbutyrate may act synergistically in treatment of the urea cycle disorders, in particular embodiments.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: December 6, 2022
    Assignee: Baylor College of Medicine
    Inventors: Juan C. Marini, Sandesh Chakravarthy Sreenath Nagamani
  • SYSTEM AND METHOD FOR A MULTI-PRIMARY WIDE GAMUT COLOR SYSTEM
    Publication number: 20220383795
    Abstract: The present invention includes systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Application
    Filed: August 3, 2022
    Publication date: December 1, 2022
    Applicant: Baylor University
    Inventors: Mitchell J. Bogdanowicz, Corey P. Carbonara, Michael F. Korpi, James M. DeFilippis, Gary B. Mandle
  • SYSTEM AND METHOD FOR A MULTI-PRIMARY WIDE GAMUT COLOR SYSTEM
    Publication number: 20220383796
    Abstract: The present invention includes systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Application
    Filed: August 1, 2022
    Publication date: December 1, 2022
    Applicant: Baylor University
    Inventors: Mitchell J. Bogdanowicz, Corey P. Carbonara, Michael F. Korpi, James M. DeFilippis, Gary B. Mandle
  • Multifunctional fluorescent and MRI-active nanostructure
    Patent number: 11504437
    Abstract: A Magnetic Resonance Imaging (MRI) enhancement agent includes a plurality of particles, each particle including: a metal core; a dielectric shell disposed on the metal core comprising at least one MRI contrast agent; and a metal shell disposed on the exterior surface of the dielectric shell that encapsulates the dielectric shell.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: November 22, 2022
    Assignees: WILLIAM MARSH RICE UNIVERSITY, BAYLOR COLLEGE OF MEDICINE
    Inventors: Nancy J. Halas, Ciceron Ayala-Orozco, Sandra Bishnoi, Luke Henderson, Oara Neumann, Robia Pautler, Peter Nordlander
  • GLUCOSE PREDICTION SYSTEMS AND ASSOCIATED METHODS
    Publication number: 20220361780
    Abstract: A method for predicting a hypoglycemic event or a hyperglycemic event includes (a) collecting one or more data streams, wherein at least one of the one or more data streams includes a glucose (GL) data stream corresponding to a user, (b) determining one or more features based on the one or more collected data streams, wherein at least one of the one or more features is distinct from each of the one or more data streams, (c) generating a prediction of whether or not a hypoglycemic event or a hyperglycemic event will occur by a prediction model based on the one or more features determined at (b), and (d) issuing an alert to the user in response to the prediction generated at (c) including a prediction that a hypoglycemic event or a hyperglycemic event will occur.
    Type: Application
    Filed: October 16, 2020
    Publication date: November 17, 2022
    Applicants: THE TEXAS A&M UNIVERSITY SYSTEM, BAYLOR COLLEGE OF MEDICINE
    Inventors: Madhav Erraguntla, Darpit K. Dave, Balakrishna Haridas, Daniel J. DeSalvo, Siripoom V. McKay, Mark Alan Lawley, Achu Geetha Byju
  • System and method for displaying super saturated color
    Patent number: 11501419
    Abstract: Systems and methods for displaying super saturated color. Image data for display on a display or viewing device with a potential white luminance in a standard system with a maximum luminance is processed such that colors near the white point are reduced to a limited luminance. As the chroma of the displayed color is increased, a luminance attenuation is decreased. The scaling of the reduction is operable to be a linear function, a non-linear function, or any other function.
    Type: Grant
    Filed: May 19, 2022
    Date of Patent: November 15, 2022
    Assignee: BAYLOR UNIVERSITY
    Inventors: Mitchell J. Bogdanowicz, James M. DeFilippis, Gary B. Mandle, Corey P. Carbonara, Michael F. Korpi
  • Targeting of SRC-3 in immune cells as an immunomodulatory therapeutic for the treatment of cancer
    Patent number: 11497772
    Abstract: The present disclosure concerns methods and compositions related to cancer treatment comprising targeting of SRC-3 in immune cells, including T cells such as T regulatory cells. The targeting of SRC-3 in T regulatory cells in particular is effective to eradicate tumors in mammals. In specific cases, the T regulatory cells are subjected to CRISPR ex vivo to produce cells suitable for adoptive cell transfer. In some cases, one or more agents that target SRC-3 are also administered to the individual and/or are exposed to the cells prior to administration.
    Type: Grant
    Filed: August 27, 2021
    Date of Patent: November 15, 2022
    Assignee: Baylor College of Medicine
    Inventors: Bert W. O'Malley, Sang Jun Han, David M. Lonard, Bryan Nikolai, Prashi Jain, Yosef Gilad, Clifford Dacso
  • System and method for a six-primary wide gamut color system
    Patent number: 11495161
    Abstract: Systems and methods for a six-primary color system for display. A six-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. The six-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Grant
    Filed: November 8, 2021
    Date of Patent: November 8, 2022
    Assignee: BAYLOR UNIVERSITY
    Inventor: Gary B. Mandle
  • System and method for a multi-primary wide gamut color system
    Patent number: 11495160
    Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Grant
    Filed: November 8, 2021
    Date of Patent: November 8, 2022
    Assignee: BAYLOR UNIVERSITY
    Inventors: Mitchell J. Bogdanowicz, James M. DeFilippis, Gary B. Mandle
  • CAR NKTs Expressing Artificial Micro RNA-Embedded shRNA for Downregulation of MHC Class I & II Expression
    Publication number: 20220348930
    Abstract: The present disclosure provides methods and compositions related to Natural Killer T cells that are engineered to knock down the expression of one or more endogenous major histocompatibility complex (MHC) gene. The present disclosure also provides engineered CAR NKT cells that resist rejection by allogeneic immune cells both in vitro and in vivo.
    Type: Application
    Filed: April 22, 2022
    Publication date: November 3, 2022
    Applicant: Baylor College of Medicine
    Inventors: Andras HECZEY, Bin LIU, Leonid METELITSA
  • Dominant active yap, a hippo effector, induces chromatin accessibility and cardiomyocyte renewal
    Patent number: 11484553
    Abstract: The present disclosure encompasses methods for generating cells or tissue from existing cells with one or more mutated variants of Yap. In specific embodiments, the disclosure regards treatment of existing cardiomyocytes with one or more mutated variants of Yap that causes them to divide and generate new cardiomyocytes. In specific cases, the mutated variant of Yap has serine-to-alanine substitutions at 1, 2, 3, 4, 5, 6, or more serines of Yap.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: November 1, 2022
    Assignee: Baylor College of Medicine
    Inventors: Tanner Monroe, John Leach, James F. Martin
  • System and method for a multi-primary wide gamut color system
    Patent number: 11488510
    Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Grant
    Filed: April 22, 2022
    Date of Patent: November 1, 2022
    Assignee: BAYLOR UNIVERSITY
    Inventors: Gary B. Mandle, James M. DeFilippis, Mitchell J. Bogdanowicz, Corey P. Carbonara, Michael F. Korpi
  • USE OF ELECTRICALLY CONDUCTIVE MATERIALS FOR ELECTROPHYSIOLOGY
    Publication number: 20220339436
    Abstract: A method of improving electrical conduction across an impaired region of a tissue (e.g., myocardial tissue), includes applying an electrically conductive wiring carbon nanotube fibers) across the impaired region. The electrically conductive wiring can become associated with non-impaired regions of the tissue on opposite sides of the impaired region by suturing. The method can also be utilized to treat or prevent cardiac arrhythmia in a subject (e.g., ventricular arrhythmia). The electrically conductive wiring includes carbon nanotubes, such as carbon nanotube fibers, Such electrically conductive wiring can be used to transmit electrical signals to a tissue or sense electrical signals from the tissue. Suture threads including carbon nanotubes, such as carbon nanotube fibers, are provided.
    Type: Application
    Filed: July 11, 2022
    Publication date: October 27, 2022
    Applicants: William Marsh Rice University, Baylor College of Medicine, Texas Heart Institute
    Inventors: Matteo Pasquali, Mehdi Razavi, Flavia Vitale, Colin Christopher Young, Mark David McCauley
  • SYSTEMS AND METHODS FOR GENERATING BACTERIOPHAGES ADAPTED TO INFECT A TARGET BACTERIAL STRAIN
    Publication number: 20220340882
    Abstract: One aspect of the invention provides a method of generating bacteriophages adapted to infect a target bacterial strain. The method comprises: providing host bacteria that are susceptible to phage as input to a host chemostat containing phage; providing target bacteria that are related to the host bacteria, but not susceptible to phage as input to a target chemostat containing phage; filtering outflows from the host chemostat and the target chemostat to isolate phage from the populations of the host bacteria, the target bacteria, and macromolecules; combining the outflows; and introducing the combined outflow into each of the host chemostat and the target chemostat.
    Type: Application
    Filed: June 25, 2020
    Publication date: October 27, 2022
    Applicant: Baylor College of Medicine
    Inventors: Justin Clark, Sabrina Green, Keiko Salazar, Austen Terwilliger, Anthony Maresso
  • SYSTEM AND METHOD FOR A MULTI-PRIMARY WIDE GAMUT COLOR SYSTEM
    Publication number: 20220343822
    Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Application
    Filed: June 24, 2022
    Publication date: October 27, 2022
    Applicant: Baylor University
    Inventors: Mitchell J. Bogdanowicz, Ph.D., Corey P. Carbonara, Ph.D., Michael F. Korpi, James M. DeFilippis, Gary B. Mandle
  • Targeted mosquitocidal toxins
    Patent number: 11479583
    Abstract: Insecticidal toxins described herein are fused toxin peptides made up of a targeting domain fused to a toxin domain. The targeting peptide generates a specific association with mosquitoes by causing the fused toxin peptide to bind mosquitoes in a way that leads to the insecticidal activity. Transgenic plants described herein are mosquitocidal by expressing an insecticidal toxin protein in nectar that includes a targeting peptide to ensure specificity against mosquitoes. These transgenic plants serve as role models for safety, since they are non-crop plants and specific to one mosquito species.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: October 25, 2022
    Assignee: BAYLOR UNIVERSITY
    Inventors: Christopher Michel Kearney, Grace Pruett
  • System and method for a multi-primary wide gamut color system
    Patent number: 11482153
    Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Grant
    Filed: June 3, 2021
    Date of Patent: October 25, 2022
    Assignee: BAYLOR UNIVERSITY
    Inventors: Gary B. Mandle, James M. DeFilippis, Mitchell J. Bogdanowicz, Corey P. Carbonara, Michael F. Korpi
  • System and method for a multi-primary wide gamut color system
    Patent number: 11475819
    Abstract: The present invention includes systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Grant
    Filed: February 11, 2022
    Date of Patent: October 18, 2022
    Assignee: BAYLOR UNIVERSITY
    Inventors: Mitchell J. Bogdanowicz, Corey P. Carbonara, Michael F. Korpi, James M. DeFilippis, Gary B. Mandle
  • Transcatheter and serially-expandable artificial heart valve
    Patent number: 11464632
    Abstract: Some embodiments are directed to a transcatheter and serially-expandable artificial heart valve, e.g., to be minimally-invasively implanted into a pediatric patient during a first procedure, and then expanded during a second procedure to accommodate for the pediatric patient's growth. Some embodiments include an expandable frame having a compressed, delivery configuration, and an expanded, deployed configuration, in which the valve is implantable within the patient. The valve can have a first working condition when the frame is expanded to a first diameter and a second working condition when the frame is expanded to a second diameter greater than the first diameter. The valve can include a plurality of leaflets configured to accommodate the expansion of the frame and growth of the patient.
    Type: Grant
    Filed: September 13, 2021
    Date of Patent: October 11, 2022
    Assignees: Baylor College of Medicine, William Marsh Rice University
    Inventors: Henri Justino, Daniel Harrington, Kwonsoo Chun