Abstract: An electrophoretic technique for assaying the relative distribution of lactate dehydrogenase (LD) isoenzymes characterized in that the electrophoretic and/or substrate buffer employed therein comprises a first and second moiety wherein the first moiety is selected from a group consisting of alkali metal 5,5-diethylbarbiturate, ammonium 5,5-diethylbarbiturate, and mixtures thereof, and wherein the second moiety is selected from a group consisting of bicine (N,N-bis(2-hydroxyethyl)glycine), tricine (N-tris(hydroxymethyl)methylglycine), and glycylglycine. The buffer has a pH of from about 7 to about 9 at 25.degree. C.Preferably, the buffer further comprises a solid organic water soluble acid and either 2-amino-2-methyl-1,3-propanediol (AMPD) or 2-amino-2-hydroxymethyl-1,3-propanediol (Tris) or mixtures thereof.Buffers within the scope of the instant invention, when compared to prior art buffers, increase the relative percentage of LD.sub.

Abstract: A sample vial guide for scintillation spectrometers or other sample handling systems in which sample vials are moved in a horizontal path to a first operating station, transferred vertically therefrom to a second station such as a radiation measuring chamber, and returned along the vertical path to the first station for continued movement along the horizontal path away from the first station. The sample vial guide includes first and second opposing jaws at the first station on opposite sides of the horizontal path and having opposing interior surfaces which surround and define a constrained area at the first station for a sample vial. The jaws are hinged to pivot laterally away from the horizontal path and include cam surfaces on each jaw for engaging a sample vial as it moves along the horizontal path to or from the first station to move the jaws to an open position to accommodate such horizontal movement of the vial.

Abstract: In a circuit for use with a multi-character alphanumeric gas discharge display tube in multiplex operation, each of the character locations is provided with a resistor between its keep-alive cathode and ground and an anode driver transistor connected in series circuit relation with each of the anodes. A switching transistor is connected to each of the resistors to shunt the resistors sequentially in response to receipt of multiplexed logic pulses. The shunting of a given resistor renders the anode driver transistor of an adjacent character conductive in response thereto.

Abstract: A method of clearing a polysaccharide ester membrane employing a clearing solvent comprising a first moiety selected from a group consisting of alcohols, ketones, ethers, esters, and mixtures thereof and a second moiety comprising a solvent selected from a group consisting of 2-ethoxyethanol, 2-ethoxyethyl acetate, methyl acetoacetate, ethyl acetoacetate, acetol, and mixtures thereof, the first moiety having a boiling point lower than the second moiety.The solvents employed as the second moiety of the instant invention's clearing solvent are much less toxic than solvents employed as the second moiety of prior art clearing solvents.

Abstract: Improved means for expelling sample carriers which have been automatically elevated to the sample measuring chamber of a radiation measuring apparatus, from the measuring chamber. The means are collapsible within the instrument housing, as to remain therein as a sample carrier is elevated toward the measuring chamber. Additionally, the means comprise a disposable contamination member which can be removed and discarded in the event of contamination.

Abstract: A multi-channel instrumentation system is provided wherein signals from selected electrode pairs are sequentially connected to the isolated input of a common signal amplifying path. The electrode pair selecting means is included in a portable head box which may be placed adjacent to the patient to be tested. Included in the head box are facilities for testing the impedance of any selected one of the patient electrodes and providing a visual indication of the magnitude of such impedance. The head box also includes facilities for selecting a group of patient electrodes which are connected together and used as an average or reference potential for one input of the common signal path. Facilities are also provided for calibrating the common signal path by applying a d.c. calibration signal to the input thereof by means isolated from system ground.

Abstract: The instant invention is a light field liquid crystal display cell with a seal and pattern layer applied to the cell substrates. Dark segments are displayed against a lighter background. Polymeric substances can be used to space and seal the cell substrates, and the light field background is created without masking the cell substrates.

Abstract: A light field liquid crystal display cell with a colored seal and pattern layer applied to the cell substrates. Dark segments are displayed against a lighter background. The light field background is created without masking the cell substrates, polymeric substances can be used to space and seal the cell substrates, and the cell is amenable for the construction of large displays.

Abstract: A secondary seal arrangement for use in a rotor to ensure the retention of the fluid sample within the test tube cavity of the rotor during high speed centrifugation in an ultracentrifuge. The secondary seal arrangement acts in cooperation with both a spacer member over the centrifuge tube and a sealing plug for the rotor cavity to provide a seal of the cavity over the test tube to reduce the possibility of escape of any fluid which may inadvertently exit the centrifuge tube itself. The secondary seal is positioned within the rotor tube cavity above the capping seal for the centrifuge tube to provide a closure of the rotor tube cavity above the centrifuge tube.

Abstract: A method and apparatus for removing moisture from a sample stream of gas while preventing dilution of the concentration of components of successive increments of the sample stream of gas.

Abstract: Titration apparatus for measuring chloride electrolyte in blood samples including a pair of coulometric generating electrodes (anode and cathode) for titrating the chloride with silver ions to precipitate silver chloride and a pair of amperometric detecting electrodes for detecting uncombined silver ions following complete titration of the chloride and hence for signaling the endpoint of the chloride titration. A predetermined potential difference is applied across the amperometric electrodes, and an operating condition of zero current flow is established through one of the amperometric electrodes. Current flow between the amperometric electrode and the coulometric anode is monitored to indicate the presence of uncombined silver ions and thereby the titration endpoint.

Abstract: Novel pentapeptides having the following amino acid sequenceX--Y--Z--E--G--J--Lwherein X is selected from a group consisting of --NH.sub.2, --NHCH.sub.3, and --N(CH.sub.3).sub.2 ; Y and G are independently selected from a group consisting of tyrosine, tryptophan, and phenylalanine, Z and E are independently selected from a group consisting of D-tyrosine, D-tryptophan, and D-phenylalanine; J is selected from a group consisting of natural amino acids and the D-configuration thereof; and L is a C-terminal functional group selected from a group consisting of amide, amide lower alkyl, amide di(lower alkyl), lower alkoxy, hydroxy, and carboxy and the lower ester derivatives thereof; and the pharmaceutically acceptable salts thereof. These peptides act directly on the pituitary to release growth hormone therefrom.

Abstract: In a digital test instrument such as a digital ohmmeter for measuring and digitally displaying the resistance of an unknown circuit element, there is included an electrical continuity tester coupled to the input of the digital ohmmeter for instantaneously and digitally indicating electrical continuity. Connection of the electrical continuity tester to the input of the digital ohmmeter is achieved in a manner such as to not overload or otherwise affect the accuracy of the resistance measurement.

Abstract: Photometric analysis apparatus in which a sample to be optically measured is stirred by a rotating magnetic stirring element within a container holding the sample. An optical path through the container and through the sample therein intersects the rotational path of the stirring element and is hence obstructed by the stirring element in one or more rotational positions. Rotation of the stirring element is controlled in a manner which stops rotation thereof in a position out of the optical path thereby allowing optical measurement of the sample material unobstructed by the stirring element.

Abstract: Novel tripeptides having the following amino acid sequenceX-Y-Z-E-Gwherein X is selected from a group consisting of --NH.sub.2, --NHCH.sub.3, and --N(CH.sub.3).sub.2 ; Y and Z are independently selected from a group consisting of D-tyrosine, D-tryptophan, and D-phenylalanine; E is selected from a group consisting of tyrosine, tryptohan, and phenylalanine; and G is a C-terminal functional group selected froma group consisting of amide, amide lower alkyl, amide di(lower alkyl), lower alkoxy, hydroxy, and carboxy and the lower ester derivatives thereof; and the pharmaceutically acceptable salts thereof. These peptides act directly on the pituitary to release growth hormone therefrom.

Abstract: Novel pentapeptides having the following amino acid sequenceX--Y--Z--E--G--J--Lwherein X is selected from a group consisting of --NH.sub.2, --NHCH.sub.3, and --N(CH.sub.3).sub.2 ; Y and G are independently selected from a group consisting of tyrosine, tryptophan, and phenylalanine; Z is selected from a group consisting of D-tyrosine, D-tryptophan, and D-phenylalanine; E is selected from a group consisting of glycine, alanine, valine, leucine, methionine, and isoleucine; J is selected from a group consisting of glycine, alanine, D-alanine, valine, D-valine, leucine, D-leucine, isoleucine, D-isoleucine, proline, D-proline, hydroxyproline, D-hydroxyproline, serine, D-serine, threonine, D-threonine, cysteine, D-cysteine, methionine, and D-methionine; and L is a C-terminal functional group selected from a group consisting of amide, amide lower alkyl, amide di(lower alkyl), lower alkoxy, hydroxy, and carboxy and the lower ester derivatives thereof; and the pharmaceutically acceptable salts thereof.

Abstract: Novel pentapeptides having the following amino acid sequenceX-Y-Z-E-G-J-Lwherein X is selected from a group consisting of --NH.sub.2, --NHCH.sub.3, and --N(CH.sub.3).sub.2 ; Y is selected from a group consisting of tyrosine, D-tyrosine, tryptophan, D-tryptophan, phenylalanine, and D-phenylalanine; Z and E are independently selected from a group consisting of D-tyrosine, D-tryptophan, and D-phenylalanine; G is selected from a group consisting of lysine and arginine; J is selected from a group consisting of glycine, alanine, valine, leucine, isoleucine, proline, hydroxyproline, serine, threonine, cysteine, and methionine; and L is a C-terminal functional group selected from a group consisting of amide, amide lower alkyl, amide di(lower alkyl), lower alkoxy, hydroxy, and carboxy and the lower ester derivatives thereof; and the pharmaceutically acceptable salts thereof. These peptides act directly on the pituitary to release growth hormone therefrom.

Abstract: Novel pentapeptides having the following amino acid sequenceX-Y-Z-E-G-J-Lwherein X is selected from a group consisting of --NH.sub.2, --NHCH.sub.3, and --N(CH.sub.3).sub.2 ; Y and G are independently selected from a group consisting of tyrosine, trytophan, and phenlalanine; Z and J are independently selected from a group consisting of D-tyrosine, D-tryptophan, an D-phenylalanine; E is selected from a group consisting of glycine, alanine, valine, leucine, isoleucine, proline, hydroxyproline, serine, threonine, cysteine, methionine, aspartic acid, glutamic acid, asparagine, glutamine, and histidine; and L is a C-terminal functional group selected from a group consisting of amide, amide lower alkyl, amide di(lower alkyl), lower alkoxy, hydroxy, and carboxy and the lower ester derivatives thereof; and the pharmaceutically acceptable salts thereof. These peptides act directly on the pituitary to release growth hormone therefrom.

Abstract: A direct drive system for a high speed ultracentrifuge. The drive spindle assembly is removable through the rotor chamber without disturbing any vacuum seals that are present to isolate the requisite vacuum environment in the rotor chamber for high speed rotation. All of the high speed bearings are connected to the spindle assembly for removal as a unit. An induction motor provides the direct drive with the motor armature mounted on the drive spindle assembly.

Abstract: A system for continuous monitoring for open circuits in multiple lead EEG systems during patient testing. Means are provided for repetitively applying a low current signal, having a distinctive waveform and frequency, to each electrode of the system. In the event an electrode is detached from the patient's scalp or otherwise open, the distinctive signal is apparent in the recorded output. Otherwise the distinctive signal is of such low magnitude that it is below the signal-to-noise ratio of the EEG amplifier. In systems including multiple leads, the test signal is successively applied to each electrode in the system in a time-controlled sequence. In one preferred embodiment a distinctive signal is used comprising a four pulse burst of 25 Hz frequency.