Patents Assigned to Becton Dickinson and Company
  • Apparatus and method for quantitative characterization of a light detector
    Patent number: 11781963
    Abstract: Aspects of the present disclosure include methods for determining a parameter of a photodetector (e.g., a photodetector in a particle analyzer). Methods according to certain embodiments include irradiating a photodetector positioned in a particle analyzer with a light source (e.g., a continuous wave light source) at a first intensity for a first predetermined time interval, irradiating the photodetector with the light source at a second intensity for a second predetermined time interval, integrating data signals from the photodetector over a period of time that includes the first predetermined interval and the second predetermined interval and determining one or more parameters of the photodetector based on the integrated data signals. Systems (e.g., particle analyzers) having light source and a photodetector for practicing the subject methods are also described.
    Type: Grant
    Filed: September 28, 2022
    Date of Patent: October 10, 2023
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Fedor Ilkov, Shreyas Bhaban
  • Catheter assembly
    Patent number: 11779734
    Abstract: A catheter assembly including a catheter carried by a catheter adapter, a needle having a sharp distal tip and disposed in the catheter such that in a first needle position, the needle extending beyond the catheter, a septum actuator having openings, the septum actuator disposed in the catheter adapter and configured to pierce a septum, and a spring clip disposed in the septum actuator and engaging the openings of the septum actuator in the first needle position.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: October 10, 2023
    Assignee: Becton, Dickinson and Company
    Inventor: S. Ray Isaacson
  • ROTATIONAL METERING PUMP FOR INSULIN PATCH
    Publication number: 20230310737
    Abstract: A rotary pump for a fluid metering system is provided. The rotary pump reciprocates, and is reversed by a signal from a limit switch that is deflected by an actuator arm on a rotating sleeve of the pump system.
    Type: Application
    Filed: December 3, 2021
    Publication date: October 5, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Alessandro Pizzochero, J. Richard Gyory, Kenneth Focht, Justin Fisk, Joseph Gordon, Matthew Perry, Ajit D'Souza, Christopher Petroff
  • Disinfection Device For Female Connectors
    Publication number: 20230310679
    Abstract: A device for connection to a female medical connector is disclosed, the device includes a cap, a scrubbing foam, an elastic sealing lip, and an absorbent material. The cap is configured to define a chamber to contain an absorbent material and disinfectant or antimicrobial agent. The cap may include one or more threads adapted to engage with a female luer connector. The device may also include a peelable seal to maintain sterility prior to use and to prevent the disinfectant or the antimicrobial agent from exiting the chamber prior to use. Also described are methods of disinfecting a medical connector.
    Type: Application
    Filed: March 30, 2022
    Publication date: October 5, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Manish Kumar, Hemant Vilas Belsare, Praveen Nalawade
  • ROTATIONAL METERING PUMP WITH CAM-DRIVEN VALVING SHUTTLE INTERLOCK
    Publication number: 20230313787
    Abstract: A rotary pump for a fluid metering system is provided. The rotary pump reciprocates, and is reversed by a signal from a limit switch that is deflected by an actuator arm on a rotating sleeve of the pump system. The rotary pump includes a plunger and optional stopper formed from a two-shot molding process, and including seals overmolded onto the head of the plunger and the head of the optional stopper.
    Type: Application
    Filed: September 28, 2021
    Publication date: October 5, 2023
    Applicant: Becton, Dickinson and Company
    Inventor: Alessandro E. PIZZOCHERO
  • Device for the attached flow of blood
    Patent number: 11771352
    Abstract: A collection device (10) which directs a flow of blood into a container (14) and provides a controlled blood flow path that ensures blood flow from a collection site to a collection container is disclosed.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: October 3, 2023
    Assignee: Becton, Dickinson and Company
    Inventors: Kishore K. Bokka Srinivasa Rao, Jayeon Kim, Milan Ivosevic
  • Cell sorting using a high throughput fluorescence flow cytometer
    Patent number: 11774343
    Abstract: In one aspect, a method of sorting cells in a flow cytometry system is disclosed, which includes illuminating a cell with radiation having at least two optical frequencies shifted from one another by a radiofrequency to elicit fluorescent radiation from the cell, detecting the fluorescent radiation to generate temporal fluorescence data, and processing the temporal fluorescence data to arrive at a sorting decision regarding the cell without generating an image (i.e., a pixel-by-pixel image) of the cell based on the fluorescence data. In some cases, the sorting decision can be made with a latency less than about 100 microseconds. In some embodiments, the above method of sorting cells can have a sub-cellular resolution. In some embodiments, a single radiofrequency shift is employed to separate the optical frequencies while in other such embodiments a plurality of different radiofrequency shifts are employed.
    Type: Grant
    Filed: July 27, 2021
    Date of Patent: October 3, 2023
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Eric D. Diebold, Keegan Owsley, Jonathan Lin
  • Catheter adapters
    Patent number: 11771882
    Abstract: A catheter adapter may include a catheter adapter body and a catheter adapter channel formed within the catheter adapter body. The catheter adapter body may include a proximal end, a distal end, an inferior surface, and a superior surface. The inferior surface of the catheter adapter body may be configured to abut against a surface area of a patient's skin, and an angle formed between the surface area of the patient's skin and a longitudinal axis of the catheter adapter channel may be greater than 4 degrees.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: October 3, 2023
    Assignee: Becton, Dickinson and Company
    Inventor: Joseph Spataro
  • Force sensing resistor for liquid low-volume detection and occlusion sensing and methods and apparatuses for flow sensing along fluid path in fluid delivery device
    Patent number: 11771824
    Abstract: A system and method is provided for detecting fluid low-volume and occlusion in a device using force sensing resistor (FSR) sensor. One or more force sensing resistors are positioned in communication with a fluid channel at one or more of a pump intake and pump outlet to detect pressure in the fluid channel. The pressure is detected through communication with the force sensing resistor and indicates an irregular system condition including but not limited to, fluid low-volume level and occlusion. Also provided are a fluid flow sensor (e.g., FSR or MEMS sensor) disposed relative to an embedded fluid channel in the base of a wearable medicine delivery pump.
    Type: Grant
    Filed: August 20, 2021
    Date of Patent: October 3, 2023
    Assignee: Becton, Dickinson and Company
    Inventors: Alessandro Pizzochero, J. Richard Gyory, Joseph Iskandar
  • Method of sample preparation for maldi and automated system therefor
    Patent number: 11774332
    Abstract: Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).
    Type: Grant
    Filed: May 18, 2022
    Date of Patent: October 3, 2023
    Assignee: BECTON DICKINSON AND COMPANY
    Inventors: Timothy Wiles, John D. Mantlo
  • High throughput multiomics sample analysis
    Patent number: 11773441
    Abstract: Disclosed herein include systems, methods, compositions, and kits for sample analysis. Nucleic acid fragments comprising a capture sequence (or a complement thereof) can be generated from double-stranded genomic deoxyribonucleic acid (gDNA), barcoded to generate single-stranded DNA (ssDNA) fragments, and sequenced. Information relating to the gDNA (e.g., genome, chromatin accessibility, methylome) can be determined based on the sequences of the ssDNA fragments in the sequencing data obtained.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: October 3, 2023
    Assignee: Becton, Dickinson and Company
    Inventors: Christina Fan, Elisabeth Marie Walczak
  • Using random priming to obtain full-length V(D)J information for immune repertoire sequencing
    Patent number: 11773436
    Abstract: Disclosed herein include systems, methods, compositions, and kits for labeling nucleic acid targets in a sample. In some embodiments, nucleic acid targets (e.g., mRNAs) are initially barcoded on the 3? end and are subsequently barcoded on the 5? end following a template switching reaction and intermolecular and/or intramolecular hybridization and extension. 5?- and/or 3?-barcoded nucleic acid targets can serve as templates for amplification reactions and/or random priming and extension reactions to generate a sequencing library. The method can comprise generating a full-length sequence of the nucleic acid target by aligning a plurality of sequencing reads. Immune repertoire profiling methods are also provided in some embodiments.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: October 3, 2023
    Assignee: Becton, Dickinson and Company
    Inventors: Christina Chang, Margaret Nakamoto
  • Assay for by amplification and detection of AP65-1 gene
    Patent number: 11773457
    Abstract: A region of the Trichomonas vaginalis AP65-1 gene has been identified which is useful for performing amplification assays to determine specifically whether T. vaginalis is present in the sample being tested. Oligonucleotides useful for performing thermal Strand Displacement Assay (tSDA) reactions on this gene are disclosed. The disclosed oligonucleotides can be used in an assay which is specific for multiple strains of T. vaginalis and which does not show cross reactivity with the genomes of other microorganisms or with human DNA.
    Type: Grant
    Filed: August 21, 2021
    Date of Patent: October 3, 2023
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventor: Ray A. McMillian
  • Disinfection Cap
    Publication number: 20230293750
    Abstract: A disinfection cap for a male medical connector comprising a housing, a scrubbing foam having a plurality of slits disposed within a first cavity of the housing, a central post extending from the closed bottom of the housing and positioned within the first cavity of the housing, a foam jacket disposed on the central post and having a plurality of slits; and a central plug disposed in the center of the central post extending from the top wall of the central post and extending into the second cavity of the foam jacket. The inner surface of the foam jacket defines a second cavity.
    Type: Application
    Filed: March 17, 2022
    Publication date: September 21, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Balaji Kannan, Karthik MR, Prasad Govindaraj, Manish Kumar
  • SAFETY DEVICE WITH COLLAPSIBLE HOUSING AND TRIGGER ACTIVATION
    Publication number: 20230293824
    Abstract: Drug delivery safety devices having trigger activation systems activated by pressure against the skin of a patient and which automatically shield the needle after withdrawing the needle from the skin of the patient.
    Type: Application
    Filed: March 31, 2023
    Publication date: September 21, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Edward P. Browka, Laurie Sanders, Eli B. Nichols, Philip C. McNeill, Robert Henson
  • Skin Preparation Applicator
    Publication number: 20230293749
    Abstract: Fluid applicators with precise volume dispensing control for dispensing fluids such as a disinfectant in a controlled manner are described herein. Such fluid applicators may include a barrel including a sidewall having an inside surface defining a chamber for retaining a fluid, an end press, a push rod disposed within the chamber, the push rod having a push button and a piercing tip, a cap attached to a port via a hinge to cover a hydrophobic filter disposed on the sidewall of the chamber, a one-way valve disposed on the outlet on a distal end of the barrel, a disinfectant disposed within the chamber; a housing having a base and an open proximal end; and a fluid applicator sponge disposed in the base of the housing. An alternate fluid may include a deformable end press, a plurality of volume scale markings on an outer surface of the barrel, a push rod, a one-way valve and applicator sponge.
    Type: Application
    Filed: March 17, 2022
    Publication date: September 21, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Manish Kumar, Karthik MR, Balaji Kannan, Prasad Govindaraj, Shishir Prasad, Kevin M. Ryan
  • Positive dispense verification sensor
    Patent number: 11759776
    Abstract: Systems and methods for positive dispense verification. In one aspect, a system has a plurality of light emitters. The light from the emitters is directed toward a plurality of light detectors across a proximately horizontal plane. The liquid dispense device is positioned above the horizontal plane of light emission from the plurality of light emitters to the plurality of light detectors such that the dispensed liquid will travel through the horizontal plane defined by the emitted light and onto the container being inoculated. Each of the plurality of detectors is coupled to an amplifier. The amplifier generates a signal in response to an interrupt in the transmission of light from the light emitters to the light detectors when the light path is disrupted by the dispense of liquid confirming the liquid was dispensed onto the container.
    Type: Grant
    Filed: October 7, 2022
    Date of Patent: September 19, 2023
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Timothy Roy Hansen, Tong Zhou
  • System and method for preparing a pharmaceutical compound
    Patent number: 11763448
    Abstract: A system for preparing a pharmaceutical compound comprises: a computing device comprising a user interface providing an operator with instructions for preparing the pharmaceutical compound and at least one processor operatively connected to the user interface; a scale operatively connected to the at least one processor; and an image capture device operatively connected to the at least one processor and the scale and positioned to capture an image of at least one of a component used in preparing the pharmaceutical compound and the pharmaceutical compound.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: September 19, 2023
    Assignee: Becton, Dickinson and Company
    Inventors: Christian Sandmann, Matt Thomas, Chris Murray, Christian Hanke, Helmut Hoerner, Robert Tannen, Mathieu Turpault, Erik Kurt Witt
  • Method for processing and displaying multi-channel spectral histograms and systems for same
    Patent number: 11761879
    Abstract: Aspects of the present disclosure include methods for processing and displaying multi-channel spectral histograms. Methods according to certain embodiments include obtaining a histogram of cytometric data for a sample, wherein the cytometric data comprises measurements from particles irradiated in the sample flowing in a flow stream, generating the representation of the histogram by encoding the histogram, the encoding comprising: assigning a color to each histogram value in the representation of the histogram, and duplicating each color corresponding to each histogram value in the representation of the histogram a predetermined number of times, and using the representation of the histogram for displaying the histogram. Systems for practicing the subject methods are also provided. Non-transitory computer readable storage mediums are also described.
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: September 19, 2023
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Christopher J. Wolf, David A. Roberts
  • DISPLACEMENT PUMP MECHANISM WITH FRANGIBLE RESERVOIR, MEDICAMENT DELIVERY SYSTEM, PATCH PUMP AND MEDICAMENT DELIVERY DEVICE
    Publication number: 20230285663
    Abstract: Medication delivery system including a container, reservoir, or chamber for medium or fluid, and a mechanism or driving components configurable outside of medium or fluid chamber for advancing a plunger to dispense medium or fluid. The system can include syringe-style drug container, reservoir, or chamber, containing medium or fluid dispensable by advancing plunger disposed inside the container, where the container includes a sliceable portion and where a cutter or slicer is configurable on plunger holder or pusher behind plunger such that cutter cuts through sliceable portion of container as plunger is advanced dispensing medium out of container. The present disclosure is further directed to a patch pump comprising the system as described above. The present disclosure is further directed to a medicament delivery device comprising the system as described above.
    Type: Application
    Filed: August 5, 2021
    Publication date: September 14, 2023
    Applicant: Becton, Dickinson and Company
    Inventors: Nitish Kumar Varma Kunaparaju, Mark Wood, Dan Yasevac, Khodabakhsh Saeedi