Abstract: In a motor vehicle air conditioning system, comprising a housing, a fan and at least one heating device, the intention is for different heating devices to be able to be fastened to a housing in a technically simple manner with low production costs. This problem is solved in that the at least one heating device is fastened to the housing, in particular exclusively, by at least one adaptor cover.

Abstract: A device for restraining an energy store is provided that includes one or more cells disposed between a first side of the energy store and a second side of the energy store vertically opposite to the first side. The device has at least one first mounting device designed for transferring a first clamping force acting in the direction of the second side to the first side of the energy store, and at least one second mounting device designed for transferring a second clamping force acting in the direction of the first side to the second side o the energy store, and at least one elastic clamping device designed for providing the first and second clamping forces and further designed for adapting a distance between the at least one first mounting device and the at least one second mounting device to a permissible distance between the first and the second side.

Abstract: The invention relates to a heat exchanger housing (1) for at least one heat exchanger for exchanging heat between a first fluid, in particular an exhaust gas or charge air, and a second fluid, in particular a coolant (6). According to the concept of the invention, a bypass duct (40) is integrated in the heat exchanger housing (1), with the housing having a housing body (10) with a chamber which is designed to be traversed by the second fluid and to hold a number of flow ducts which can be traversed by the first fluid; a bypass duct (40) which is designed to be traversed by the first fluid; with the chamber and the bypass duct (40) being formed in one piece with the housing body (10).

Abstract: This application provides, inter alia, processes for producing an integral bond between a high-grade steel component and an aluminum or aluminum alloy component. In an exemplary embodiment, the process comprises coating the high-grade steel first with a nickel layer and second an aluminum layer, arranging the coated high-grade steel and the aluminum or aluminum alloy components in relation to one another in such a manner that partial regions of the first and of the second component are arranged parallel to one another and either bear areally against one another or are arranged with a gap of 0 mm to 5 mm in relation to one another, and integrally bonding the coated high-grade steel component to the aluminum or aluminum alloy component by using a cold metal transfer process.

Abstract: The present invention relates to a process for producing frame elements for a frame for holding and arranging electrochemical cells in an electrochemical energy-storage unit. The present invention also relates to the use of certain plastics mixtures for producing said frame elements. The frame elements or frames of the invention are particularly preferably used in electrochemical energy-storage units with high power density. Electrochemical energy-storage units of this type with high power density are more particularly used for the operation of motor vehicles with electrical drive, for example in vehicles which are driven on the “hybrid” principle (electrical drive and internal combustion engine), and are also preferably used for exclusively or primarily electrically operated vehicles. It is preferable here to use, as electrochemical energy-storage units with high power density, lithium-ion batteries or lithium-polymer batteries.

Abstract: A heat exchanger includes a tube with a heat-exchange passage and an end piece. The heat-exchange passage directs the flow of a first medium and includes a first flow section and a second flow section arranged in parallel. The end piece has a tube plate that includes a base plate, a diverter plate, and a cover plate. An end of the tube connects to the base plate. The diverter plate has a cutout that forms a diverter passage. The cover plate lies adjacent to the diverter plate and covers the diverter passage in a fluid-tight manner. A second medium flows exterior to the heat-exchange passage.

Abstract: The invention relates to a device for pressing a cooler against a battery, said cooler having at least one cooling surface for absorbing or dissipating thermal energy, and the battery having at least one contact surface for the cooling surface of the cooler to rest on. The device comprises a pressure part having at least one spring-elastic pressure element for transmitting a contact pressure onto a section of the surface of the cooler facing away from the battery. The device further comprises at least one suspension unit for suspending the pressure part on the battery, said suspension unit being designed such as to generate a suspension force which is counter to the contact force when the cooler is arranged on the battery and the suspension unit is suspended on the battery.

Abstract: The field of the invention is the treatment of acquired bleeding, a clinical condition associated with severe traumatic, peri- or post-operative bleeding. A novel treatment is proposed in which synergistic pro-coagulatory properties of Prothrombin Complex Concentrates (PCC) together with medicaments comprising FVIII and/or vWF are exploited.

Abstract: The invention relates to a heat exchanger for a motor vehicle, comprising a first flow path (1), a deflection region (13) located downstream of the first flow path (1) and a second flow path (2) that is located downstream of the deflection region (13). The first and second flow paths (1, 2) can be traversed by a fluid to be cooled and can be surrounded by a coolant to dissipate heat. The second flow path (2) has a flow resistance that differs from that of the first flow path (1).

Abstract: An exhaust gas recirculation system is provided that includes an internal combustion engine, which is supplied with exhaust gas, diverted at a removal point and returned via a return point and/or charge air, having a heat exchanger arranged between the removal point and the return point, for the returned exhaust gas and/or the charge air, and having an exhaust gas recirculation valve, by means of which the amount of returned exhaust gas and/or charge air can be regulated. To provide an exhaust gas recirculation system, which has a simple structure and can be manufactured cost-effectively, the exhaust gas recirculation valve is connectable between the removal point and the heat exchanger.

Abstract: A cooling apparatus for a motor vehicle with an internal combustion engine is provided that includes at least one heat exchanger through which air can pass, at least one axial fan that is located behind the at least one heat exchanger in a direction of air flow and has a circumferential ring with which ring is associated a stationary baffle ring, and a fan shroud adjoining the at least one heat exchanger. At least one motion compensating element with a sealing function is provided between the baffle ring and the at least one fan shroud.

Abstract: The present invention relates to modified nucleic acid sequences coding for coagulation factor VIII (FVIII) and for von Willebrand factor (VWF) as well as complexes thereof and their derivatives, recombinant expression vectors containing such nucleic acid sequences, host cells transformed with such recombinant expression vectors, recombinant polypeptides and derivatives coded for by said nucleic acid sequences which recombinant polypeptides and derivatives do have biological activities together with prolonged in vivo half-life and/or improved in vivo recovery compared to the unmodified wild-type protein. The invention also relates to corresponding FVIII sequences that result in improved expression yield. The present invention further relates to processes for the manufacture of such recombinant proteins and their derivatives. The invention also relates to a transfer vector for use in human gene therapy, which comprises such modified nucleic acid sequences.

Abstract: This invention relates to protein separation and purification methods for both alpha-1-antitrypsin (AAT, also known as alpha-1 proteinase inhibitor, API, and A.sub.1-PI) and Apolipoprotein A-I (ApoA-1) from, for example, a fraction of human blood plasma. In certain embodiments, the invention provides methods for separating AAT from ApoA-1 at the initial stage of purification, so that the same starting material can be used as a source for both proteins. The methods further pertain to providing compositions of AAT and of ApoA-1 suitable for pharmaceutical use and are suitable for large-scale purification.

Abstract: Disclosed herein is a fan comprising fan blades, especially for a cooler of a motor vehicle, said fan blades being fixed to a fan hub. In spite of being made of only a small amount of material, said fan is highly resistant to the flow conditions in the motor vehicle, each fan blade being bent rearwards at an angle in the direction of a blade root, an angled region of the fan blade being at least partially bent downwards towards the fan hub.

Abstract: The present invention relates to a device for cooling charge air for an internal combustion engine of a vehicle. The device comprises a plurality of first coolant pipes for conducting a first coolant and a plurality of second coolant pipes for conducting a second coolant, wherein the first coolant pipes and the second coolant pipes extend in a longitudinal extension direction of the device and the plurality of first coolant pipes is arranged adjacent to the plurality of second coolant pipes in a transverse extension direction of the device.

Abstract: The invention relates to a method for operating a circuit having a heat accumulator, having a coolant circuit, having a heat accumulator in a line of the circuit and having at least one valve and one pump, wherein, when the valve is open, the heat accumulator can be charged with coolant from the coolant circuit by means of the pump, or coolant can be discharged from the heat accumulator into the coolant circuit, wherein the charging or discharging of the heat accumulator takes place in an open-loop-controlled or closed-loop-controlled manner as a function of a temperature difference of a temperature of the coolant in the circuit and a temperature of the coolant in the heat accumulator.

Abstract: The invention relates to a method for producing a metal part. Said method comprises the steps of supplying a strand of metal material and applying a coating from a fluxing agent composition to a surface of the strand of material by means of an application device (1), said fluxing agent composition being applied to only a defined portion of the surface of the strand of material by means of the application device (1).

Abstract: The invention relates to a cooler arrangement for a drive train (21) in a motor vehicle (23). Said cooler arrangement comprises a first coolant circuit (3) with a first coolant cooler (7) as well as a second coolant circuit (5) with a second coolant cooler (9). The invention is characterized in that there is a connection between the first coolant circuit (3) and the second coolant circuit (5).

Abstract: The aim of the invention is to provide a fluxing agent for soldering components, which creates one or more specific surface characteristics during the soldering process itself, thus obviating the need for the surface treatment process that is conventionally carried out after the soldering process. To achieve this, nanoparticles are added to a base substance.

Abstract: The invention relates to a plate-shaped heat exchanger for a cooling device comprising at least one heat exchanger package, in particular for a motor vehicle, consisting of a plurality of openings for accommodating a pipe conducting a coolant, wherein each opening is surrounded by an passage and a plurality of projections are distributed between the passages for the heat exchange with the medium to be cooled. In order to allow a high performance increase of a cooling device, yet a low increase in pressure loss of the charge air, a plurality of projections are arranged around an passage, wherein the projections have a shape that assures deliberate heat conduction from the projections to the passage.