Abstract: A heat exchanger is provided that includes plate pairs stacked one above the other. A first flow chamber is formed between the two plates of a plate pair by conducting a first fluid therethrough, a second flow chamber for conducting a second fluid therethrough, wherein the second flow chamber is formed between two adjacent plate pairs, an inlet opening for introducing the first fluid, and an outlet opening for discharging the first fluid. The plates have at least one expansion opening, in particular at least one expansion slit, for reducing stress in the plates. The heat exchanger can withstand high thermal and mechanical loads even over a long time period, such as 10 years.

Abstract: The present invention relates to modified cDNA sequences coding for vitamin K-dependent polypeptides, in particular human Factor VII, human Factor VIIa, human Factor IX and human protein C and their derivatives with improved stability and extended plasma half life, recombinant expression vectors containing such cDNA sequences, host cells transformed with such recombinant expression vectors, recombinant polypeptides and derivatives which do have biological activities of the unmodified wild type protein but having improved stability and processes for the manufacture of such recombinant proteins and their derivatives. The invention also covers a transfer vector for use in human gene therapy, which comprises such modified DNA sequences.

Abstract: A heat exchanger assembly may include an intercooler and a housing which encloses said intercooler. The housing may be part of a charge air line. The housing may include a charge air inlet, a charge air outlet and an opening through which the intercooler can be inserted into the housing from one side. The housing may also include a recess on the side opposite the opening, into which recess the intercooler engages. The heat exchanger assembly may include an elastic seal arranged in the region of the recess between the intercooler and the housing. The seal may be configured to at least one of bridge the deformation of the housing occurring during pressure pulsations, bridge relative movements between the intercooler and the housing, and tightly connect the intercooler to the housing in all operating states preventing an undesirable bypass flow.

Abstract: The present invention relates to the field of modified therapeutic polypeptides with increased in vivo recovery compared to their non-modified parent polypeptide. For example, the invention relates to fusions of therapeutic polypeptides with recovery enhancing polypeptides connected directly or optionally connected by a linker peptide.

Abstract: A charge air duct for an internal combustion engine includes a housing with at least one entrance and at least one exit for charge air. A heat exchanger is arranged inside the housing to cool the charge air, a bypass is arranged on the housing to at least partially circumvent the heat exchanger and an actuator is arranged on the housing to influence the charge air flow. The charge air is guided from the entrance to the heat exchanger in a first position of the actuator and from the entrance to the bypass in a second position of the actuator, and the actuator at least partially reduces a cross-section of the charge air in a third position.

Abstract: A thermoelectric module may include a fluid-tight housing having at least one thermoelectrically active element arranged therein. The at least one thermoelectrically active element may have a coating. The housing may form an outer encapsulation and the coating may form an inner encapsulation for the at least one thermoelectrically active element.

Abstract: Heat pump comprising a number of hollow elements (2) with a first zone (2a), a second zone (2b) and a working medium which can be displaced in a reversible manner between the first and second zones, also comprising a number of plate elements (1) and a number of through-passage regions of a first type (4) arranged between the plate elements (1), further comprising a number of through-passage regions of a second type (5) arranged between the plate elements (1), and additionally comprising at least two distributing devices (7, 8) which are arranged at the ends of the plate elements (1) in each case, are provided for distributing a first fluid through the through-passage regions of the first type (4) and each have a fixed hollow cylinder and a distributor insert (7a, 8a) which can be rotated in the hollow cylinder, the distributor insert (7a, 8a) having partition walls (7b, 8b) which separate off at least four separate chambers (11) in each of the cylinders, and a flow path which comprises at least one through-pa

Abstract: The invention relates to a module for a heat pump, comprising an adsorption-desorption region, wherein in the region a bundle of pipes through which fluid can flow is arranged and a housing encloses the pipe bundle and a movable working medium in a sealing manner, wherein a supporting structure forms a mechanical support of a wall of the housing against the action of an external pressure.

Abstract: A thermal transfer device for generating a thermal transfer between an energy store and a temperature-control panel for the temperature-control of the energy store. The thermal transfer device has a thermal insulation layer made of an unevenly distributed insulation material and a tolerance compensating layer made of a compressible material for compensating different material strengths of the thermal insulation layer.

Abstract: An exhaust gas cooler for a motor vehicle is provided that includes a first collector box on an inlet side and a second collector box on an outlet side, and a plurality of exchanger tubes extending between the collector boxes for exhaust gas to flow through. Air can flow around the exchanger tubes so as to cool the exhaust gas. At least one supporting member is attached to at least one of the collector boxes, a force produced by the thermal expansion of the exchanger tubes being passed into the supporting member.

Abstract: The invention relates to a thermoelectric module, having an electric insulation, an electric conductor path, one surface of the electric conductor path being attached to a surface of the electrical insulation, and a thermoelectric material, one surface of the thermoelectric material being attached to another surface of the conductor path.

Abstract: A device for cooling a vehicle battery is provided that includes a plurality of electrical storage elements, and a cooling element having ducts for a fluid to flow through, wherein the electrical storage elements are in thermal contact with the cooling elements and heat can be transmitted from the storage elements to the fluid, and wherein the cooling element which comprises the ducts is embodied as at least one extruded profile.

Abstract: A heat transfer device for a motor vehicle may include a pump and a heat exchanger. The heat exchanger may have a first inlet and a first outlet for a refrigerant, and a second inlet and a second outlet for a coolant. The pump and the heat exchanger may be mounted to each other forming a common assembly.

Abstract: Disclosed herein is a heat exchanger with a housing casing, a first base and a second base with openings, pipes as a first flow channel for conducting a first fluid, the ends thereof being arranged in or on the openings of the first and second bases, the pipes and the first and/or the second base are arranged within the housing so that a second flow channel for conducting a second fluid is designed between the housing and the pipes, a first inlet opening for the first fluid, a first outlet opening for the first fluid, a second inlet opening for the second fluid, a second outlet opening for the second fluid, a first diffusor for directing the first fluid into the pipes, a second diffuser for directing the first fluid out of the pipes, which heat exchanger should be simple and cost-effective to produce and ensure reliable operation.

Abstract: A cooling device for a battery module and a battery device comprising said cooling device for a battery module are provided that includes a cooling element having at least one through hole extending from a first side of the cooling element facing the battery module to an opposite second side of the cooling element, at least one spring element disposed on the second side of the cooling element, in order to exert a contact force on the second side of the cooling element in a tensioned condition, and at least one clamping device coupled to the spring element and extending through the through hole, wherein a contact region of the clamping device extends beyond the second side of the cooling element when the spring element is in a relaxed condition.

Abstract: The present invention relates to the fields of Factor VII (FVII) and Factor VIIa (FVIIa) albumin linked polypeptides. More specifically, the invention relates to cDNA sequences coding for human Factor VII and Factor VIIa and derivatives genetically fused to a cDNA coding for human serum albumin which may be linked by oligonucleotides which code for intervening peptidic linkers such encoded derivatives exhibiting improved stability and extended functional plasma half-life, recombinant expression vectors containing such cDNA sequences, host cells transformed with such recombinant expression vectors, recombinant polypeptides and derivatives which do have biological activities of the unmodified wild type protein but having improved stability and prolonged shelf-life and processes for the manufacture of such recombinant proteins and their derivatives. The invention also covers a transfer vector for use in human gene therapy, which comprises such modified DNA sequences.

Abstract: A heat exchanger of a type with a collector plate which has a wall in which are formed rim holes which can receive the ends of tubes of a bundle, wherein the wall of the collector plate is designed such that, for the purpose of a soldered or welded connection to the tubes, it forms collars around the rim holes, and wherein the wall has a front side facing toward the tube bundle and a rear side facing toward the collecting tank. Each collar extends in the direction of the collecting tank from a straight base plane on the rear side of the wall.

Abstract: Disclosed herein is a heat exchanger, comprising at least one electric resistance heating element, at least two conductors which are connected to the at least one electric resistance heating element in an electrically conductive manner in order to conduct electric current through the at least one electric resistance heating element and thereby heat the electric resistance heating element, at least one thermally conductive element for transferring heat from the at least one electric resistance heating element to a fluid to be heated, at least one electrically insulating element, which electrically insulates the at least two conductors, and at least one pipe, wherein the at least two conductors and the at least one electric resistance heating element are arranged within a cavity bounded by the pipe and the pipe lies on the at least one electrically insulating element under a compressive force at at least one contact surface.

Abstract: The present invention relates to nucleic acid sequences coding for modified coagulation factors, preferably coagulation factor VIII, and their derivatives; recombinant expression vectors containing such nucleic acid sequences; host cells transformed with such recombinant expression vectors; and recombinant polypeptides and derivatives coded for by said nucleic acid sequences, whereby said recombinant polypeptides and derivatives have biological activities and prolonged in vivo half-lives compared to the unmodified wild-type proteins. The invention also relates to corresponding sequences that result in improved in vitro stability. The present invention further relates to processes for the manufacture of such recombinant proteins and their derivatives. The invention also relates to a transfer vector for use in human gene therapy, which comprises such nucleic acid sequences.

Abstract: The invention relates to an air-cooled exhaust gas heat exchanger, in particular exhaust gas cooler (1) for motor vehicles comprising channels (exhaust gas channels) which can be cross-flown by the exhaust gas of an internal combustion engine, between which ribs (4) for air cooling are arranged. According to the invention, the exhaust gas channels are embodied as tubes, in particular as flat tubes (3), which form the ribs (4) of a rib tube block (2) and the tube (3) has tube ends (3a) which are received in the collecting vessels (5) for the exhaust gas.